| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
151 | B1AUC7 | 590 | RHG36_MOUSE Rho GTPase-activating protein 36 ... | 133 | 0.000000001 | 65.9 | 32 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 152 | Q54WY8 | 611 | GACN_DICDI Rho GTPase-activating protein gacN... | 173 | 0.000000002 | 65.5 | 27 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 153 | Q71FD7 | 375 | FBLI1_MOUSE Filamin-binding LIM protein 1 OS=... | 160 | 0.000000002 | 64.7 | 29 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 154 | Q6GPD0 | 1940 | RHG32_XENLA Rho GTPase-activating protein 32 ... | 206 | 0.000000002 | 65.9 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 155 | Q28FG2 | 833 | PRIC1_XENTR Prickle-like protein 1 OS=Xenopus... | 156 | 0.000000002 | 65.5 | 31 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB.::GO:0001736; P:establishment of planar polarity; ISS:UniProtKB. | 156 | Q5VT97 | 1194 | SYDE2_HUMAN Rho GTPase-activating protein SYD... | 191 | 0.000000002 | 65.9 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 157 | P53670 | 638 | LIMK2_RAT LIM domain kinase 2 OS=Rattus norve... | 92 | 0.0003 | 48.5 | 33 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007286; P:spermatid development; TAS:RGD. | 158 | Q8WUP2 | 373 | FBLI1_HUMAN Filamin-binding LIM protein 1 OS=... | 144 | 0.000000002 | 64.3 | 31 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0016337; P:cell-cell adhesion; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; IMP:UniProtKB. | 159 | B5DFQ4 | 759 | RHG26_XENTR Rho GTPase-activating protein 26 ... | 133 | 0.000000002 | 65.1 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 160 | O14559 | 1287 | RHG33_HUMAN Rho GTPase-activating protein 33 ... | 243 | 0.000000002 | 65.5 | 26 | 43 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 161 | A6X8Z5 | 1425 | RHG31_MOUSE Rho GTPase-activating protein 31 ... | 223 | 0.000000003 | 65.5 | 26 | 44 | GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0030027; C:lamellipodium; IDA:MGI. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI. | 162 | Q04584 | 542 | ZYX_CHICK Zyxin OS=Gallus gallus (Chicken). G... | 65 | 1.9 | 36.2 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 163 | Q2M1Z3 | 1444 | RHG31_HUMAN Rho GTPase-activating protein 31 ... | 271 | 0.000000003 | 65.1 | 25 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 164 | Q80YF9 | 1305 | RHG33_MOUSE Rho GTPase-activating protein 33 ... | 244 | 0.000000003 | 65.1 | 25 | 43 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro. | 165 | O54785 | 638 | LIMK2_MOUSE LIM domain kinase 2 OS=Mus muscul... | 92 | 0.003 | 45.4 | 32 | 46 | GO:0005801; C:cis-Golgi network; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007283; P:spermatogenesis; IMP:MGI. | 166 | Q80W90 | 388 | LHX9_RAT LIM/homeobox protein Lhx9 OS=Rattus ... | 92 | 0.001 | 46.2 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 167 | Q1JQB5 | 378 | FBLI1_BOVIN Filamin-binding LIM protein 1 OS=... | 144 | 0.000000004 | 63.5 | 31 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 168 | Q9NQ69 | 397 | LHX9_HUMAN LIM/homeobox protein Lhx9 OS=Homo ... | 92 | 0.001 | 46.2 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 169 | Q90WV2 | 832 | PRI1B_XENLA Prickle-like protein 1-B OS=Xenop... | 156 | 0.000000004 | 64.3 | 31 | 46 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; ISS:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; ISS:UniProtKB. | 170 | Q90Z06 | 835 | PRI1A_XENLA Prickle-like protein 1-A OS=Xenop... | 156 | 0.000000005 | 64.3 | 30 | 44 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009948; P:anterior/posterior axis specification; IMP:UniProtKB.::GO:0060027; P:convergent extension involved in gastrulation; IMP:UniProtKB.::GO:0001736; P:establishment of planar polarity; IMP:UniProtKB. | 171 | Q8R5G7 | 1538 | ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ... | 158 | 0.000000005 | 64.7 | 30 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro. | 172 | Q96P48 | 1450 | ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 178 | 0.000000005 | 64.7 | 31 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 173 | P85298 | 464 | RHG08_HUMAN Rho GTPase-activating protein 8 O... | 214 | 0.000000005 | 63.5 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 174 | Q9WUH2 | 397 | LHX9_MOUSE LIM/homeobox protein Lhx9 OS=Mus m... | 92 | 0.001 | 46.2 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:MGI.::GO:0008585; P:female gonad development; IMP:MGI.::GO:0035262; P:gonad morphogenesis; IMP:MGI.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 175 | Q5REN1 | 375 | FBLI1_PONAB Filamin-binding LIM protein 1 OS=... | 144 | 0.000000005 | 63.2 | 31 | 44 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 176 | O74360 | 933 | RGA4_SCHPO Probable Rho-type GTPase-activatin... | 152 | 0.000000006 | 64.3 | 22 | 50 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0070650; P:actin filament bundle distribution; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IMP:PomBase.::GO:0032231; P:regulation of actin filament bundle assembly; IMP:PomBase.::GO:0060305; P:regulation of cell diameter; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 177 | A0JNI8 | 397 | LHX9_BOVIN LIM/homeobox protein Lhx9 OS=Bos t... | 92 | 0.001 | 46.2 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 178 | E9Q6X9 | 672 | RHG40_MOUSE Rho GTPase-activating protein 40 ... | 187 | 0.000000006 | 63.9 | 30 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 179 | Q5U4T3 | 771 | RHG26_XENLA Rho GTPase-activating protein 26 ... | 130 | 0.000000006 | 63.9 | 33 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 180 | Q1LWV4 | 396 | LHX9_DANRE LIM/homeobox protein Lhx9 OS=Danio... | 92 | 0.002 | 45.8 | 26 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB. | 181 | Q9BE31 | 847 | RHG12_MACFA Rho GTPase-activating protein 12 ... | 186 | 0.000000007 | 63.9 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |
