| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q9UTM0 | 249 | YIV2_SCHPO Zinc finger protein C144.02 OS=Sch... | 274 | 5e-46 | 164 | 41 | 53 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031011; C:Ino80 complex; IDA:PomBase. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006357; P:regulation of transcription from RNA polymerase II promoter; NAS:PomBase. | 2 | P55878 | 556 | GLI1_CHICK Zinc finger protein GLI1 OS=Gallus... | 142 | 1e-19 | 94 | 33 | 55 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 3 | Q61602 | 1583 | GLI3_MOUSE Transcriptional activator GLI3 OS=... | 91 | 5e-19 | 92.8 | 41 | 62 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IGI:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060873; P:anterior semicircular canal development; IMP:MGI.::GO:0009952; P:anterior/posterior pattern specification; IMP:MGI.::GO:0060840; P:artery development; IGI:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:MGI.::GO:0048593; P:camera-type eye morphogenesis; IMP:MGI.::GO:0061005; P:cell differentiation involved in kidney development; IGI:MGI.::GO:0021801; P:cerebral cortex radial glia guided migration; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048557; P:embryonic digestive tract morphogenesis; IMP:MGI.::GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.::GO:0048704; P:embryonic skeletal system morphogenesis; IGI:MGI.::GO:0021798; P:forebrain dorsal/ventral pattern formation; IMP:MGI.::GO:0021861; P:forebrain radial glial cell differentiation; IMP:MGI.::GO:0060364; P:frontal suture morphogenesis; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0007442; P:hindgut morphogenesis; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0060366; P:lambdoid suture morphogenesis; IMP:MGI.::GO:0022018; P:lateral ganglionic eminence cell proliferation; IMP:MGI.::GO:0060875; P:lateral semicircular canal development; IMP:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0060594; P:mammary gland specification; IGI:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0001656; P:metanephros development; IGI:MGI.::GO:0046639; P:negative regulation of alpha-beta T cell differentiation; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:BHF-UCL.::GO:0045060; P:negative thymic T cell selection; IMP:BHF-UCL.::GO:0042475; P:odontogenesis of dentin-containing tooth; IGI:MGI.::GO:0048709; P:oligodendrocyte differentiation; IGI:MGI.::GO:0021631; P:optic nerve morphogenesis; IMP:MGI.::GO:0060021; P:palate development; IMP:MGI.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; IMP:BHF-UCL.::GO:0032332; P:positive regulation of chondrocyte differentiation; IMP:MGI.::GO:0002052; P:positive regulation of neuroblast proliferation; IMP:MGI.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:MGI.::GO:0042307; P:positive regulation of protein import into nucleus; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0016485; P:protein processing; IDA:MGI.::GO:0009954; P:proximal/distal pattern formation; IMP:MGI.::GO:0060367; P:sagittal suture morphogenesis; IMP:MGI.::GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IGI:MGI.::GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IGI:MGI.::GO:0070242; P:thymocyte apoptotic process; IMP:BHF-UCL.::GO:0043586; P:tongue development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 4 | P10071 | 1580 | GLI3_HUMAN Transcriptional activator GLI3 OS=... | 91 | 7e-19 | 92.4 | 41 | 63 | GO:0005929; C:cilium; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0035035; F:histone acetyltransferase binding; IPI:UniProtKB.::GO:0042826; F:histone deacetylase binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042733; P:embryonic digit morphogenesis; TAS:BHF-UCL.::GO:0046639; P:negative regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045060; P:negative thymic T cell selection; ISS:BHF-UCL.::GO:0043585; P:nose morphogenesis; TAS:BHF-UCL.::GO:0046638; P:positive regulation of alpha-beta T cell differentiation; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070242; P:thymocyte apoptotic process; ISS:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 5 | Q5IS56 | 1580 | GLI3_PANTR Transcriptional activator GLI3 OS=... | 91 | 7e-19 | 92.4 | 41 | 63 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 6 | Q91660 | 1569 | GLI3_XENLA Zinc finger protein GLI3 OS=Xenopu... | 91 | 9e-19 | 92 | 40 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 7 | Q9IA31 | 1544 | GLI3_CHICK Transcriptional activator GLI3 OS=... | 91 | 1e-18 | 91.7 | 40 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0060173; P:limb development; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 8 | Q91661 | 1361 | GLI4_XENLA Zinc finger protein GLI4 OS=Xenopu... | 91 | 5e-18 | 89.7 | 40 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | P55879 | 663 | GLI2_CHICK Zinc finger protein GLI2 OS=Gallus... | 91 | 1e-17 | 88.2 | 40 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | P47806 | 1111 | GLI1_MOUSE Zinc finger protein GLI1 OS=Mus mu... | 102 | 4e-17 | 87 | 36 | 62 | GO:0005929; C:cilium; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0008017; F:microtubule binding; IDA:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0021696; P:cerebellar cortex morphogenesis; IGI:MGI.::GO:0009953; P:dorsal/ventral pattern formation; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0060032; P:notochord regression; IGI:MGI.::GO:0021983; P:pituitary gland development; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009954; P:proximal/distal pattern formation; IGI:MGI.::GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IGI:MGI.::GO:0007283; P:spermatogenesis; IDA:MGI.::GO:0007418; P:ventral midline development; IGI:MGI. | 11 | P19538 | 1397 | CI_DROME Transcriptional activator cubitus in... | 119 | 5e-17 | 86.7 | 34 | 53 | GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0035301; C:Hedgehog signaling complex; IPI:FlyBase.::GO:0016020; C:membrane; IDA:FlyBase.::GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035017; P:cuticle pattern formation; IMP:FlyBase.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0008544; P:epidermis development; IMP:FlyBase.::GO:0048592; P:eye morphogenesis; IMP:FlyBase.::GO:0035224; P:genital disc anterior/posterior pattern formation; IEP:FlyBase.::GO:0060914; P:heart formation; IMP:FlyBase.::GO:0035217; P:labial disc development; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0030858; P:positive regulation of epithelial cell differentiation; IMP:FlyBase.::GO:0045750; P:positive regulation of S phase of mitotic cell cycle; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0007367; P:segment polarity determination; IMP:UniProtKB.::GO:0007224; P:smoothened signaling pathway; IMP:FlyBase.::GO:0035277; P:spiracle morphogenesis, open tracheal system; IMP:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048100; P:wing disc anterior/posterior pattern formation; IMP:FlyBase. | 12 | P08151 | 1106 | GLI1_HUMAN Zinc finger protein GLI1 OS=Homo s... | 91 | 1e-16 | 85.5 | 38 | 63 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048546; P:digestive tract morphogenesis; TAS:BHF-UCL.::GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB. | 13 | P10070 | 1586 | GLI2_HUMAN Zinc finger protein GLI2 OS=Homo s... | 106 | 1e-16 | 85.5 | 35 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0021696; P:cerebellar cortex morphogenesis; ISS:UniProtKB.::GO:0048589; P:developmental growth; ISS:UniProtKB.::GO:0048566; P:embryonic digestive tract development; ISS:UniProtKB.::GO:0009913; P:epidermal cell differentiation; IDA:UniProtKB.::GO:0021508; P:floor plate formation; ISS:UniProtKB.::GO:0007507; P:heart development; ISS:UniProtKB.::GO:0007442; P:hindgut morphogenesis; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0042475; P:odontogenesis of dentin-containing tooth; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IDA:UniProtKB.::GO:0021983; P:pituitary gland development; ISS:UniProtKB.::GO:0045740; P:positive regulation of DNA replication; IDA:UniProtKB.::GO:0033089; P:positive regulation of T cell differentiation in thymus; ISS:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0009954; P:proximal/distal pattern formation; ISS:UniProtKB.::GO:0001501; P:skeletal system development; ISS:UniProtKB.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; ISS:UniProtKB.::GO:0021965; P:spinal cord ventral commissure morphogenesis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | Q91690 | 1360 | GLI1_XENLA Zinc finger protein GLI1 OS=Xenopu... | 144 | 3e-16 | 84.3 | 34 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q0VGT2 | 1544 | GLI2_MOUSE Zinc finger protein GLI2 OS=Mus mu... | 106 | 7e-16 | 83.2 | 34 | 55 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0031512; C:motile primary cilium; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IGI:MGI.::GO:0007411; P:axon guidance; IMP:MGI.::GO:0048754; P:branching morphogenesis of a tube; IMP:MGI.::GO:0008283; P:cell proliferation; IGI:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0021696; P:cerebellar cortex morphogenesis; IMP:MGI.::GO:0090103; P:cochlea morphogenesis; IMP:MGI.::GO:0048589; P:developmental growth; IMP:MGI.::GO:0048566; P:embryonic digestive tract development; IMP:MGI.::GO:0042733; P:embryonic digit morphogenesis; IMP:MGI.::GO:0021508; P:floor plate formation; IMP:MGI.::GO:0060322; P:head development; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0007442; P:hindgut morphogenesis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001822; P:kidney development; IGI:MGI.::GO:0030324; P:lung development; IMP:MGI.::GO:0060603; P:mammary gland duct morphogenesis; IMP:MGI.::GO:0032331; P:negative regulation of chondrocyte differentiation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0060032; P:notochord regression; IGI:MGI.::GO:0042475; P:odontogenesis of dentin-containing tooth; IMP:MGI.::GO:0002076; P:osteoblast development; IDA:MGI.::GO:0021983; P:pituitary gland development; IGI:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0060513; P:prostatic bud formation; IMP:MGI.::GO:0008589; P:regulation of smoothened signaling pathway; IMP:MGI.::GO:0001501; P:skeletal system development; IMP:MGI.::GO:0060831; P:smoothened signaling pathway involved in dorsal/ventral neural tube patterning; IGI:MGI.::GO:0021938; P:smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation; IMP:MGI.::GO:0021776; P:smoothened signaling pathway involved in spinal cord motor neuron cell fate specification; IGI:MGI.::GO:0021775; P:smoothened signaling pathway involved in ventral spinal cord interneuron specification; IGI:MGI.::GO:0021965; P:spinal cord ventral commissure morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q17308 | 1165 | TRA1_CAEBR Sex-determining transformer protei... | 109 | 0.00004 | 49.7 | 30 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0019099; P:female germ-line sex determination; TAS:UniProtKB.::GO:0019101; P:female somatic sex determination; TAS:UniProtKB.::GO:0007548; P:sex differentiation; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 17 | Q8VDL9 | 521 | GLIS2_MOUSE Zinc finger protein GLIS2 OS=Mus ... | 68 | 0.00003 | 49.3 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 18 | Q8K1M4 | 789 | GLIS1_MOUSE Zinc finger protein GLIS1 OS=Mus ... | 93 | 0.00004 | 49.7 | 30 | 52 | GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | Q8NBF1 | 620 | GLIS1_HUMAN Zinc finger protein GLIS1 OS=Homo... | 93 | 0.00007 | 48.5 | 30 | 52 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB. | 20 | Q7TQ40 | 622 | ZIC5_MOUSE Zinc finger protein ZIC 5 OS=Mus m... | 136 | 0.000000005 | 61.6 | 32 | 48 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI. | 21 | Q62521 | 466 | ZIC3_MOUSE Zinc finger protein ZIC 3 OS=Mus m... | 118 | 0.0000008 | 54.3 | 35 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; IGI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0035545; P:determination of left/right asymmetry in nervous system; IMP:UniProtKB.::GO:0001947; P:heart looping; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 22 | O60481 | 467 | ZIC3_HUMAN Zinc finger protein ZIC 3 OS=Homo ... | 118 | 0.0000007 | 54.7 | 35 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 23 | P34708 | 1110 | TRA1_CAEEL Sex-determining transformer protei... | 109 | 0.0000002 | 56.6 | 31 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019099; P:female germ-line sex determination; TAS:UniProtKB.::GO:0019101; P:female somatic sex determination; TAS:UniProtKB.::GO:0008406; P:gonad development; IGI:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040039; P:inductive cell migration; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0043525; P:positive regulation of neuron apoptotic process; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 24 | Q9IB89 | 515 | ZIC5_XENLA Zinc finger protein ZIC 5 OS=Xenop... | 124 | 0.000005 | 52 | 33 | 46 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0014029; P:neural crest formation; IMP:UniProtKB. | 25 | Q96T25 | 663 | ZIC5_HUMAN Zinc finger protein ZIC 5 OS=Homo ... | 88 | 0.000001 | 54.3 | 36 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW. | 26 | Q9YIB7 | 497 | ZIC2B_XENLA Zinc finger protein ZIC 2-B OS=Xe... | 89 | 0.0000001 | 56.6 | 38 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009952; P:anterior/posterior pattern specification; ISS:UniProtKB.::GO:0042074; P:cell migration involved in gastrulation; ISS:UniProtKB.::GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0014034; P:neural crest cell fate commitment; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB. | 27 | Q98T94 | 492 | GLIS2_XENLA Zinc finger protein GLIS2 OS=Xeno... | 68 | 0.00003 | 49.7 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 28 | Q8NEA6 | 775 | GLIS3_HUMAN Zinc finger protein GLIS3 OS=Homo... | 93 | 0.00002 | 50.1 | 30 | 52 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB. | 29 | Q9BZE0 | 524 | GLIS2_HUMAN Zinc finger protein GLIS2 OS=Homo... | 68 | 0.00004 | 49.3 | 32 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB. | | | | | | | | | | GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; ISS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW. | 30 | Q6XP49 | 780 | GLIS3_MOUSE Zinc finger protein GLIS3 OS=Mus ... | 93 | 0.000007 | 51.6 | 30 | 53 | GO:0044428; C:nuclear part; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB. | 31 | O95409 | 532 | ZIC2_HUMAN Zinc finger protein ZIC 2 OS=Homo ... | 91 | 0.0000002 | 56.6 | 37 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0031490; F:chromatin DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007420; P:brain development; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; ISS:UniProtKB. |
