| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P12461 | 315 | TYSY_CANAL Thymidylate synthase OS=Candida al... | 338 | 4e-135 | 394 | 57 | 70 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 2 | P06785 | 304 | TYSY_YEAST Thymidylate synthase OS=Saccharomy... | 332 | 1e-133 | 390 | 57 | 69 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IDA:SGD. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 3 | P0CS12 | 317 | TYSY_CRYNJ Thymidylate synthase OS=ATCC MYA-5... | 332 | 8e-133 | 389 | 60 | 69 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 4 | P0CS13 | 317 | TYSY_CRYNB Thymidylate synthase OS=(Filobasid... | 332 | 8e-133 | 389 | 60 | 69 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 5 | P13100 | 297 | TYSY_PNECA Thymidylate synthase OS=Pneumocyst... | 332 | 3e-132 | 387 | 57 | 69 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 6 | Q9UTI7 | 625 | TYSY_SCHPO Probable thymidylate synthase OS=S... | 332 | 1e-125 | 381 | 56 | 69 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; ISS:PomBase. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; ISS:PomBase. | 7 | Q9P4T7 | 296 | TYSY_AGABI Thymidylate synthase OS=Agaricus b... | 333 | 2e-124 | 367 | 56 | 68 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 8 | Q05763 | 565 | DRTS2_ARATH Bifunctional dihydrofolate reduct... | 334 | 3e-123 | 373 | 56 | 67 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 9 | O81395 | 521 | DRTS_MAIZE Bifunctional dihydrofolate reducta... | 334 | 5e-122 | 369 | 54 | 67 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 10 | Q05762 | 519 | DRTS1_ARATH Bifunctional dihydrofolate reduct... | 334 | 4e-119 | 361 | 54 | 65 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 11 | P07607 | 307 | TYSY_MOUSE Thymidylate synthase OS=Mus muscul... | 339 | 2e-118 | 352 | 53 | 65 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | | 12 | Q2QRX6 | 494 | DRTS_ORYSJ Putative bifunctional dihydrofolat... | 334 | 3e-118 | 358 | 54 | 65 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 13 | P45352 | 307 | TYSY_RAT Thymidylate synthase OS=Rattus norve... | 345 | 1e-117 | 350 | 51 | 64 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.::GO:0005730; C:nucleolus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0048037; F:cofactor binding; IDA:RGD.::GO:0008144; F:drug binding; IPI:RGD.::GO:0005542; F:folic acid binding; IDA:RGD.::GO:0003729; F:mRNA binding; IPI:RGD.::GO:0000166; F:nucleotide binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0004799; F:thymidylate synthase activity; IDA:RGD. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0051216; P:cartilage development; IEP:RGD.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0048589; P:developmental growth; IEP:RGD.::GO:0006231; P:dTMP biosynthetic process; IDA:RGD.::GO:0046078; P:dUMP metabolic process; IDA:RGD.::GO:0019088; P:immortalization of host cell by virus; IEP:RGD.::GO:0060574; P:intestinal epithelial cell maturation; IEP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0005976; P:polysaccharide metabolic process; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0051593; P:response to folic acid; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033189; P:response to vitamin A; IEP:RGD.::GO:0046653; P:tetrahydrofolate metabolic process; IEP:RGD.::GO:0019860; P:uracil metabolic process; IEP:RGD. | 14 | P51820 | 530 | DRTS_SOYBN Bifunctional dihydrofolate reducta... | 336 | 1e-116 | 355 | 53 | 66 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 15 | P04818 | 313 | TYSY_HUMAN Thymidylate synthase OS=Homo sapie... | 333 | 3e-114 | 341 | 52 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; TAS:Reactome. | | | | | | | | | | GO:0006281; P:DNA repair; NAS:UniProtKB.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:UniProtKB.::GO:0006206; P:pyrimidine base metabolic process; TAS:Reactome.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0046683; P:response to organophosphorus; IEP:UniProtKB. | 16 | P45350 | 528 | DRTS_DAUCA Bifunctional dihydrofolate reducta... | 339 | 8e-114 | 348 | 52 | 63 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 17 | Q89940 | 289 | TYSY_EHV2 Thymidylate synthase OS=Equine herp... | 333 | 2e-113 | 338 | 53 | 64 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 18 | O76511 | 321 | TYSY_DROME Thymidylate synthase OS=Drosophila... | 350 | 9e-113 | 338 | 50 | 60 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 19 | P06854 | 294 | TYSY_SHV21 Thymidylate synthase OS=Saimiriine... | 334 | 3e-112 | 335 | 51 | 62 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 20 | Q27828 | 462 | DRTS_PARTE Bifunctional dihydrofolate reducta... | 333 | 3e-111 | 339 | 49 | 65 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 21 | P12462 | 290 | TYSY_HSVAT Thymidylate synthase OS=Herpesviru... | 333 | 1e-109 | 328 | 50 | 62 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 22 | Q07422 | 610 | DRTS_TOXGO Bifunctional dihydrofolate reducta... | 333 | 2e-108 | 337 | 51 | 64 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 23 | P90463 | 337 | TYSY_HHV8P Thymidylate synthase OS=sarcoma-as... | 353 | 2e-108 | 327 | 52 | 60 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 24 | O96650 | 294 | TYSY_ASCSU Thymidylate synthase OS=Ascaris su... | 337 | 7e-108 | 324 | 50 | 63 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 25 | Q2TA32 | 354 | TYSY_BOVIN Thymidylate synthase OS=Bos taurus... | 371 | 1e-107 | 326 | 47 | 58 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 26 | P20712 | 583 | DRTS_PLACH Bifunctional dihydrofolate reducta... | 332 | 2e-101 | 317 | 46 | 60 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 27 | P16126 | 520 | DRTS_LEIAM Bifunctional dihydrofolate reducta... | 333 | 3e-101 | 315 | 50 | 61 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 28 | P13922 | 608 | DRTS_PLAFK Bifunctional dihydrofolate reducta... | 332 | 2e-100 | 316 | 45 | 60 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 29 | P07382 | 520 | DRTS_LEIMA Bifunctional dihydrofolate reducta... | 333 | 3e-100 | 312 | 50 | 62 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro.::GO:0006545; P:glycine biosynthetic process; IEA:InterPro.::GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 30 | Q4JQW2 | 301 | TYSY_VZVO Thymidylate synthase OS=3). GN=ORF1... | 331 | 6e-100 | 304 | 47 | 62 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. | 31 | P09249 | 301 | TYSY_VZVD Thymidylate synthase OS=Varicella-z... | 331 | 6e-100 | 304 | 47 | 62 | | | | | | | | | | | GO:0004799; F:thymidylate synthase activity; IEA:EC. | | | | | | | | | | GO:0006231; P:dTMP biosynthetic process; IEA:InterPro. |
