| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | A7Z026 | 699 | PPR37_BOVIN Protein phosphatase 1 regulatory ... | 88 | 2.8 | 33.9 | 33 | 49 | | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 62 | P59047 | 1200 | NALP5_HUMAN NACHT, LRR and PYD domains-contai... | 151 | 3.3 | 33.9 | 23 | 44 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 63 | Q5FVQ8 | 973 | NLRX1_RAT NLR family member X1 OS=Rattus norv... | 135 | 3.7 | 33.9 | 27 | 37 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 64 | P59046 | 1061 | NAL12_HUMAN NACHT, LRR and PYD domains-contai... | 68 | 3.7 | 33.9 | 35 | 59 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008656; F:cysteine-type endopeptidase activator activity involved in apoptotic process; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:HGNC.::GO:0050711; P:negative regulation of interleukin-1 secretion; IDA:HGNC.::GO:0045409; P:negative regulation of interleukin-6 biosynthetic process; IDA:HGNC.::GO:0031953; P:negative regulation of protein autophosphorylation; IDA:HGNC.::GO:0045751; P:negative regulation of Toll signaling pathway; IDA:HGNC.::GO:0050729; P:positive regulation of inflammatory response; NAS:UniProtKB.::GO:0050718; P:positive regulation of interleukin-1 beta secretion; NAS:UniProtKB.::GO:0045381; P:regulation of interleukin-18 biosynthetic process; NAS:UniProtKB.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB. | 65 | Q9NR96 | 1032 | TLR9_HUMAN Toll-like receptor 9 OS=Homo sapie... | 123 | 3.9 | 33.5 | 28 | 45 | GO:0016324; C:apical plasma membrane; IDA:BHF-UCL.::GO:0016323; C:basolateral plasma membrane; IDA:BHF-UCL.::GO:0032009; C:early phagosome; ISS:UniProtKB.::GO:0036020; C:endolysosome membrane; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0000139; C:Golgi membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005149; F:interleukin-1 receptor binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0035197; F:siRNA binding; IMP:UniProtKB. | | | | | | | | | | GO:0042742; P:defense response to bacterium; NAS:UniProtKB.::GO:0007252; P:I-kappaB phosphorylation; IDA:BHF-UCL.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0030277; P:maintenance of gastrointestinal epithelium; ISS:BHF-UCL.::GO:0032715; P:negative regulation of interleukin-6 production; ISS:BHF-UCL.::GO:0032717; P:negative regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.::GO:0032722; P:positive regulation of chemokine production; IDA:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0050729; P:positive regulation of inflammatory response; IC:BHF-UCL.::GO:0045356; P:positive regulation of interferon-alpha biosynthetic process; IDA:UniProtKB.::GO:0045359; P:positive regulation of interferon-beta biosynthetic process; IDA:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; ISS:BHF-UCL.::GO:0045078; P:positive regulation of interferon-gamma biosynthetic process; IDA:UniProtKB.::GO:0032733; P:positive regulation of interleukin-10 production; ISS:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; ISS:BHF-UCL.::GO:0032741; P:positive regulation of interleukin-18 production; ISS:BHF-UCL.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:BHF-UCL.::GO:0032757; P:positive regulation of interleukin-8 production; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IC:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; ISS:BHF-UCL.::GO:0034123; P:positive regulation of toll-like receptor signaling pathway; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:BHF-UCL.::GO:0032760; P:positive regulation of tumor necrosis factor production; ISS:BHF-UCL.::GO:0002237; P:response to molecule of bacterial origin; TAS:BHF-UCL. | 66 | C6FG12 | 1726 | NLRC5_ICTPU Protein NLRC5 OS=Ictalurus puncta... | 187 | 4.5 | 33.5 | 22 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW. | 67 | Q0P5G1 | 1374 | TONSL_BOVIN Tonsoku-like protein OS=Bos tauru... | 103 | 4.6 | 33.5 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0031297; P:replication fork processing; ISS:UniProtKB. | 68 | Q647I9 | 1098 | NALP5_BOVIN NACHT, LRR and PYD domains-contai... | 258 | 5.3 | 33.1 | 23 | 39 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. | | | | | | | | | | | 69 | Q8CIM1 | 670 | LRC45_MOUSE Leucine-rich repeat-containing pr... | 197 | 6.9 | 32.7 | 24 | 43 | | | | | | | | | | | | | | | | | | | | | | 70 | Q640Z9 | 509 | LRC14_XENLA Leucine-rich repeat-containing pr... | 187 | 7.8 | 32.3 | 27 | 43 | | | | | | | | | | | | | | | | | | | | | | 71 | Q9R1M5 | 1163 | NALP5_MOUSE NACHT, LRR and PYD domains-contai... | 212 | 7.9 | 32.7 | 25 | 41 | GO:0045179; C:apical cortex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0043623; P:cellular protein complex assembly; IMP:MGI.::GO:0007566; P:embryo implantation; IMP:MGI.::GO:0009566; P:fertilization; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0031647; P:regulation of protein stability; IMP:MGI.::GO:0043487; P:regulation of RNA stability; IMP:MGI. | 72 | Q5TCX8 | 1036 | M3KL4_HUMAN Mitogen-activated protein kinase ... | 66 | 8.5 | 32.7 | 32 | 56 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. |
