rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8K3Z0 | 1020 | NOD2_MOUSE Nucleotide-binding oligomerization... | 131 | 0.076 | 39.3 | 29 | 47 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005829; C:cytosol; ISS:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC.::GO:0031982; C:vesicle; ISS:HGNC. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050700; F:CARD domain binding; ISS:HGNC.::GO:0016888; F:endodeoxyribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0032500; F:muramyl dipeptide binding; ISS:HGNC.::GO:0019901; F:protein kinase binding; ISS:HGNC. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; IDA:BHF-UCL.::GO:0071224; P:cellular response to peptidoglycan; IMP:MGI.::GO:0002367; P:cytokine production involved in immune response; ISS:UniProtKB.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:MGI.::GO:0016045; P:detection of bacterium; ISS:HGNC.::GO:0032498; P:detection of muramyl dipeptide; ISS:HGNC.::GO:0002381; P:immunoglobulin production involved in immunoglobulin mediated immune response; IMP:MGI.::GO:0006954; P:inflammatory response; TAS:HGNC.::GO:0002227; P:innate immune response in mucosa; IMP:MGI.::GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.::GO:0071608; P:macrophage inflammatory protein-1 alpha production; IMP:MGI.::GO:0044130; P:negative regulation of growth of symbiont in host; IMP:MGI.::GO:0002862; P:negative regulation of inflammatory response to antigenic stimulus; IMP:MGI.::GO:0032689; P:negative regulation of interferon-gamma production; IMP:MGI.::GO:0032695; P:negative regulation of interleukin-12 production; IDA:MGI.::GO:0032701; P:negative regulation of interleukin-18 production; IMP:MGI.::GO:0032703; P:negative regulation of interleukin-2 production; IMP:MGI.::GO:2000110; P:negative regulation of macrophage apoptotic process; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:MGI.::GO:0002710; P:negative regulation of T cell mediated immunity; IMP:MGI.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; IMP:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:MGI.::GO:0006965; P:positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria; IMP:MGI.::GO:0002606; P:positive regulation of dendritic cell antigen processing and presentation; IMP:BHF-UCL.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0002925; P:positive regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:MGI.::GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:UniProtKB.::GO:0032733; P:positive regulation of interleukin-10 production; IMP:BHF-UCL.::GO:0032735; P:positive regulation of interleukin-12 production; IDA:MGI.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; IDA:MGI.::GO:0046330; P:positive regulation of JNK cascade; IDA:MGI.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:MGI.::GO:0051770; P:positive regulation of nitric-oxide synthase biosynthetic process; IMP:BHF-UCL.::GO:0045747; P:positive regulation of Notch signaling pathway; IDA:BHF-UCL.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0050766; P:positive regulation of phagocytosis; IMP:MGI.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:BHF-UCL.::GO:2000363; P:positive regulation of prostaglandin-E synthase activity; IDA:BHF-UCL.::GO:0060585; P:positive regulation of prostaglandin-endoperoxide synthase activity; IDA:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0032760; P:positive regulation of tumor necrosis factor production; IDA:MGI.::GO:0002830; P:positive regulation of type 2 immune response; ISS:BHF-UCL.::GO:0051259; P:protein oligomerization; TAS:HGNC.::GO:0090022; P:regulation of neutrophil chemotaxis; IMP:MGI.::GO:0043330; P:response to exogenous dsRNA; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI. | 32 | A0JPI9 | 479 | CN16B_RAT Uncharacterized protein C14orf166B ... | 233 | 0.087 | 38.9 | 22 | 42 | | | | | | | | | | | | | | | | | | | | | | 33 | A2VDH3 | 298 | LRC38_MOUSE Leucine-rich repeat-containing pr... | 157 | 0.12 | 37.7 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 34 | Q53B88 | 1040 | NOD2_HYLLA Nucleotide-binding oligomerization... | 112 | 0.15 | 38.1 | 31 | 46 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031982; C:vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050700; F:CARD domain binding; ISS:UniProtKB.::GO:0032500; F:muramyl dipeptide binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0002367; P:cytokine production involved in immune response; ISS:UniProtKB.::GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0016045; P:detection of bacterium; ISS:UniProtKB.::GO:0032498; P:detection of muramyl dipeptide; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0050718; P:positive regulation of interleukin-1 beta secretion; ISS:UniProtKB.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 35 | Q5ZI11 | 670 | LRC45_CHICK Leucine-rich repeat-containing pr... | 74 | 8.8 | 32.3 | 28 | 45 | | | | | | | | | | | | | | | | | | | | | | 36 | Q5JU00 | 501 | TCTE1_HUMAN T-complex-associated testis-expre... | 144 | 0.39 | 36.6 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 37 | Q5R1V9 | 359 | PGS2_PANTR Decorin OS=Pan troglodytes (Chimpa... | 233 | 0.32 | 36.6 | 27 | 43 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 38 | P07585 | 359 | PGS2_HUMAN Decorin OS=Homo sapiens (Human). G... | 233 | 0.32 | 36.6 | 27 | 43 | GO:0005615; C:extracellular space; IDA:BHF-UCL. | | | | | | | | | | | | | | | | | | | | GO:0009887; P:organ morphogenesis; TAS:ProtInc. | 39 | P28675 | 357 | PGS2_CHICK Decorin OS=Gallus gallus (Chicken)... | 135 | 0.44 | 36.2 | 30 | 48 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 40 | Q6E804 | 1013 | NOD2_BOVIN Nucleotide-binding oligomerization... | 103 | 0.46 | 36.6 | 33 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046645; P:positive regulation of gamma-delta T cell activation; IMP:BHF-UCL.::GO:0002830; P:positive regulation of type 2 immune response; ISS:BHF-UCL. | 41 | Q3TL44 | 975 | NLRX1_MOUSE NLR family member X1 OS=Mus muscu... | 114 | 0.47 | 36.6 | 32 | 51 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW. | 42 | Q9DE68 | 356 | PGS2_COTJA Decorin OS=Coturnix coturnix japon... | 145 | 0.48 | 36.2 | 29 | 47 | GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 43 | Q4R642 | 501 | TCTE1_MACFA T-complex-associated testis-expre... | 144 | 1.2 | 35 | 27 | 43 | | | | | | | | | | | | | | | | | | | | | | 44 | P0CD60 | 1489 | FRMC_DICDI FERM domain-containing protein C O... | 80 | 6.8 | 32.7 | 28 | 49 | GO:0005856; C:cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | | 45 | Q6ZQY2 | 391 | YV012_HUMAN Leucine-rich repeat-containing pr... | 247 | 0.61 | 35.8 | 22 | 45 | | | | | | | | | | | | | | | | | | | | | | 46 | B0FPE9 | 1035 | NALP3_MACMU NACHT, LRR and PYD domains-contai... | 231 | 2.8 | 34.3 | 24 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 47 | C0LGR3 | 1091 | Y4265_ARATH Probable LRR receptor-like serine... | 86 | 1.1 | 35.4 | 31 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 48 | Q54Q39 | 336 | PP1R7_DICDI Protein phosphatase 1 regulatory ... | 90 | 1.1 | 35 | 31 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 49 | A6QLE5 | 1031 | NALP3_BOVIN NACHT, LRR and PYD domains-contai... | 112 | 9.8 | 32.3 | 26 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 50 | Q86YC3 | 692 | LRC33_HUMAN Leucine-rich repeat-containing pr... | 61 | 1.4 | 35 | 43 | 56 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 51 | Q288C4 | 996 | NALP9_BOVIN NACHT, LRR and PYD domains-contai... | 115 | 1.4 | 35 | 30 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 52 | Q96HA7 | 1378 | TONSL_HUMAN Tonsoku-like protein OS=Homo sapi... | 115 | 1.5 | 35 | 27 | 44 | GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0043596; C:nuclear replication fork; IDA:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc. | | | | | | | | | | GO:0042994; P:cytoplasmic sequestering of transcription factor; TAS:ProtInc.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:UniProtKB.::GO:0031297; P:replication fork processing; IMP:UniProtKB. | 53 | Q8BKR5 | 712 | PPR37_MOUSE Protein phosphatase 1 regulatory ... | 216 | 2.1 | 34.3 | 25 | 41 | | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 54 | Q5PP26 | 424 | PII2_ARATH Piriformospora indica-insensitive ... | 123 | 2.1 | 34.3 | 29 | 49 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | GO:0009610; P:response to symbiotic fungus; IMP:TAIR.::GO:0044403; P:symbiosis, encompassing mutualism through parasitism; IMP:TAIR. | 55 | B2RYF1 | 710 | PPR37_RAT Protein phosphatase 1 regulatory su... | 213 | 8.9 | 32.3 | 25 | 41 | | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 56 | P49606 | 2493 | CYAA_USTMA Adenylate cyclase OS=Ustilago mayd... | 86 | 2.3 | 34.3 | 36 | 51 | | | | | | | | | | | GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 57 | P93194 | 1109 | RPK1_IPONI Receptor-like protein kinase OS=Ip... | 99 | 2.6 | 34.3 | 31 | 42 | GO:0005576; C:extracellular region; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0019199; F:transmembrane receptor protein kinase activity; NAS:UniProtKB. | | | | | | | | | | | 58 | Q86UT6 | 975 | NLRX1_HUMAN NLR family member X1 OS=Homo sapi... | 166 | 2.6 | 34.3 | 27 | 39 | GO:0005741; C:mitochondrial outer membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome. | 59 | Q86W24 | 1093 | NAL14_HUMAN NACHT, LRR and PYD domains-contai... | 179 | 2.7 | 34.3 | 25 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IMP:UniProtKB. | 60 | P12024 | 1315 | CHAO_DROME Chaoptin OS=Drosophila melanogaste... | 111 | 2.7 | 34.3 | 28 | 45 | GO:0005886; C:plasma membrane; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0007156; P:homophilic cell adhesion; IDA:FlyBase.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042052; P:rhabdomere development; IGI:FlyBase.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 61 | A7Z026 | 699 | PPR37_BOVIN Protein phosphatase 1 regulatory ... | 88 | 2.8 | 33.9 | 33 | 49 | | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. |