| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
601 | Q63531 | 735 | KS6A1_RAT Ribosomal protein S6 kinase alpha-1... | 272 | 0.000000000004 | 74.7 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004711; F:ribosomal protein S6 kinase activity; TAS:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:RGD. | 602 | Q9GN62 | 617 | PAR4_CAEEL Serine/threonine-protein kinase pa... | 289 | 1e-23 | 111 | 29 | 47 | GO:0005938; C:cell cortex; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IPI:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:WormBase. | | | | | | | | | | GO:0008356; P:asymmetric cell division; IMP:WormBase.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IGI:WormBase.::GO:0030010; P:establishment of cell polarity; IMP:WormBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IMP:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase. | 603 | P97820 | 1233 | M4K4_MOUSE Mitogen-activated protein kinase k... | 304 | 1e-23 | 112 | 31 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0046328; P:regulation of JNK cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; IDA:UniProtKB. | 604 | Q13237 | 762 | KGP2_HUMAN cGMP-dependent protein kinase 2 OS... | 272 | 1e-23 | 112 | 29 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 605 | P41279 | 467 | M3K8_HUMAN Mitogen-activated protein kinase k... | 277 | 1e-23 | 109 | 32 | 45 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:InterPro.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 606 | P05132 | 351 | KAPCA_MOUSE cAMP-dependent protein kinase cat... | 290 | 1e-23 | 108 | 29 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0031594; C:neuromuscular junction; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0071374; P:cellular response to parathyroid hormone stimulus; IMP:MGI.::GO:0001707; P:mesoderm formation; IGI:MGI.::GO:0071158; P:positive regulation of cell cycle arrest; IDA:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IMP:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0048240; P:sperm capacitation; IDA:UniProtKB. | 607 | P22987 | 891 | KIN1_SCHPO Protein kinase kin1 OS=Schizosacch... | 291 | 1e-23 | 112 | 28 | 46 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0015630; C:microtubule cytoskeleton; TAS:PomBase.::GO:0035839; C:non-growing cell tip; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0060632; P:regulation of microtubule-based movement; IMP:PomBase.::GO:0010687; P:site selection involved in cell cycle cytokinesis; IMP:PomBase. | 608 | Q63553 | 746 | SNRK_RAT SNF-related serine/threonine-protein... | 276 | 1e-23 | 111 | 27 | 51 | GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0043523; P:regulation of neuron apoptotic process; TAS:UniProtKB. | 609 | Q62101 | 918 | KPCD1_MOUSE Serine/threonine-protein kinase D... | 271 | 1e-23 | 112 | 29 | 51 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; IMP:UniProtKB. | 610 | Q9WTQ1 | 918 | KPCD1_RAT Serine/threonine-protein kinase D1 ... | 271 | 1e-23 | 112 | 29 | 51 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; ISS:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0060548; P:negative regulation of cell death; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB. | 611 | P0C431 | 357 | HOG1_GIBZE Mitogen-activated protein kinase H... | 322 | 1e-23 | 108 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 612 | P22694 | 351 | KAPCB_HUMAN cAMP-dependent protein kinase cat... | 329 | 2e-23 | 108 | 27 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; TAS:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IDA:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0034199; P:activation of protein kinase A activity; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0071377; P:cellular response to glucagon stimulus; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007188; P:G-protein signaling, coupled to cAMP nucleotide second messenger; TAS:UniProtKB.::GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0007243; P:intracellular protein kinase cascade; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0019433; P:triglyceride catabolic process; TAS:Reactome.::GO:0006833; P:water transport; TAS:Reactome. | 613 | P06244 | 397 | KAPA_YEAST cAMP-dependent protein kinase type... | 276 | 2e-23 | 108 | 29 | 46 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007265; P:Ras protein signal transduction; IMP:SGD. | 614 | P18652 | 752 | KS6AA_CHICK Ribosomal protein S6 kinase 2 alp... | 281 | 0.000000000008 | 73.9 | 27 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 615 | P05131 | 351 | KAPCB_BOVIN cAMP-dependent protein kinase cat... | 329 | 2e-23 | 108 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 616 | Q91604 | 432 | STK11_XENLA Serine/threonine-protein kinase s... | 295 | 2e-23 | 108 | 26 | 47 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016020; C:membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0030295; F:protein kinase activator activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030010; P:establishment of cell polarity; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0072332; P:signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0001944; P:vasculature development; ISS:UniProtKB. | 617 | Q9WV60 | 420 | GSK3B_MOUSE Glycogen synthase kinase-3 beta O... | 214 | 2e-23 | 108 | 32 | 51 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:MGI.::GO:0005829; C:cytosol; IDA:MGI.::GO:0043198; C:dendritic shaft; IDA:MGI.::GO:0030426; C:growth cone; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.::GO:0005625; C:soluble fraction; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:MGI. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0007409; P:axonogenesis; IGI:MGI.::GO:0044337; P:canonical Wnt receptor signaling pathway involved in positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0016477; P:cell migration; IGI:MGI.::GO:0008283; P:cell proliferation; TAS:MGI.::GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0001837; P:epithelial to mesenchymal transition; ISS:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0045444; P:fat cell differentiation; IDA:MGI.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0044027; P:hypermethylation of CpG island; IMP:BHF-UCL.::GO:0007520; P:myoblast fusion; IDA:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; ISS:UniProtKB.::GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:MGI.::GO:0010800; P:positive regulation of peptidyl-threonine phosphorylation; IDA:MGI.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0006611; P:protein export from nucleus; IDA:MGI.::GO:0035372; P:protein localization to microtubule; IGI:MGI.::GO:0000320; P:re-entry into mitotic cell cycle; IDA:MGI.::GO:0006349; P:regulation of gene expression by genetic imprinting; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IDA:UniProtKB. | 618 | Q60EY8 | 466 | CIPKK_ORYSJ CBL-interacting protein kinase 20... | 282 | 2e-23 | 109 | 32 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 619 | P34208 | 496 | CHK1_SCHPO Serine/threonine-protein kinase ch... | 276 | 2e-23 | 109 | 27 | 47 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005654; C:nucleoplasm; TAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000077; P:DNA damage checkpoint; IGI:PomBase. | 620 | Q90321 | 397 | MP2K2_CYPCA Dual specificity mitogen-activate... | 208 | 2e-23 | 108 | 35 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 621 | P52497 | 620 | SNF1_CANAX Carbon catabolite-derepressing pro... | 309 | 2e-23 | 110 | 27 | 47 | GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW. | 622 | P49841 | 420 | GSK3B_HUMAN Glycogen synthase kinase-3 beta O... | 214 | 2e-23 | 108 | 32 | 51 | GO:0034747; C:Axin-APC-beta-catenin-GSK3B complex; IDA:BHF-UCL.::GO:0030877; C:beta-catenin destruction complex; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008013; F:beta-catenin binding; IPI:BHF-UCL.::GO:0051059; F:NF-kappaB binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IDA:MGI.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:UniProtKB.::GO:0050321; F:tau-protein kinase activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060070; P:canonical Wnt receptor signaling pathway; IC:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0001837; P:epithelial to mesenchymal transition; IMP:UniProtKB.::GO:0006983; P:ER overload response; IDA:MGI.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IDA:BHF-UCL.::GO:0021766; P:hippocampus development; IMP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:UniProtKB.::GO:0032091; P:negative regulation of protein binding; IDA:BHF-UCL.::GO:0031333; P:negative regulation of protein complex assembly; IMP:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0001954; P:positive regulation of cell-matrix adhesion; IMP:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IC:BHF-UCL.::GO:0031334; P:positive regulation of protein complex assembly; IDA:BHF-UCL.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0032855; P:positive regulation of Rac GTPase activity; IMP:BHF-UCL.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0071109; P:superior temporal gyrus development; IMP:BHF-UCL. | 623 | O09110 | 347 | MP2K3_MOUSE Dual specificity mitogen-activate... | 277 | 2e-23 | 108 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060048; P:cardiac muscle contraction; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0042035; P:regulation of cytokine biosynthetic process; IMP:MGI. | 624 | Q0D0P5 | 364 | HOG1_ASPTN Mitogen-activated protein kinase h... | 322 | 2e-23 | 108 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 625 | Q15139 | 912 | KPCD1_HUMAN Serine/threonine-protein kinase D... | 271 | 2e-23 | 111 | 29 | 51 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0035924; P:cellular response to vascular endothelial growth factor stimulus; IMP:UniProtKB.::GO:0007030; P:Golgi organization; IMP:UniProtKB.::GO:0048193; P:Golgi vesicle transport; ISS:UniProtKB.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0007243; P:intracellular protein kinase cascade; IMP:BHF-UCL.::GO:0060548; P:negative regulation of cell death; IMP:UniProtKB.::GO:0045806; P:negative regulation of endocytosis; TAS:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IMP:BHF-UCL.::GO:0032793; P:positive regulation of CREB transcription factor activity; IGI:BHF-UCL.::GO:2001028; P:positive regulation of endothelial cell chemotaxis; IMP:BHF-UCL.::GO:0001938; P:positive regulation of endothelial cell proliferation; IGI:BHF-UCL.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0045669; P:positive regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:BHF-UCL.::GO:2001044; P:regulation of integrin-mediated signaling pathway; TAS:BHF-UCL.::GO:0010837; P:regulation of keratinocyte proliferation; ISS:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 626 | O55099 | 343 | AURKB_RAT Aurora kinase B OS=Rattus norvegicu... | 221 | 2e-23 | 107 | 32 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:RGD.::GO:0005819; C:spindle; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0008283; P:cell proliferation; IEP:RGD.::GO:0000910; P:cytokinesis; IDA:RGD.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 627 | A4IFM7 | 623 | MYLK2_BOVIN Myosin light chain kinase 2, skel... | 279 | 2e-23 | 110 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | | 628 | Q6A1A2 | 396 | PDPK2_HUMAN Putative 3-phosphoinositide-depen... | 263 | 2e-23 | 108 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 629 | O43283 | 966 | M3K13_HUMAN Mitogen-activated protein kinase ... | 243 | 2e-23 | 111 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB. | | | | | | | | | | GO:0007254; P:JNK cascade; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB. | 630 | P05383 | 351 | KAPCB_PIG cAMP-dependent protein kinase catal... | 329 | 2e-23 | 107 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB. | | | | | | | | | | | 631 | P68182 | 351 | KAPCB_RAT cAMP-dependent protein kinase catal... | 334 | 2e-23 | 107 | 27 | 44 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:RGD.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; IC:RGD. | | | | | | | | | | GO:0051447; P:negative regulation of meiotic cell cycle; IDA:RGD. |
