| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q6BRY2 | 330 | PHO85_DEBHA Negative regulator of the PHO sys... | 309 | 4e-26 | 116 | 26 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 392 | P22216 | 821 | RAD53_YEAST Serine/threonine-protein kinase R... | 280 | 4e-26 | 120 | 31 | 51 | GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009202; P:deoxyribonucleoside triphosphate biosynthetic process; IMP:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD. | 393 | P31938 | 393 | MP2K1_MOUSE Dual specificity mitogen-activate... | 309 | 4e-26 | 116 | 30 | 47 | GO:0005829; C:cytosol; TAS:UniProtKB.::GO:0005769; C:early endosome; TAS:UniProtKB.::GO:0005925; C:focal adhesion; TAS:UniProtKB.::GO:0005794; C:Golgi apparatus; TAS:UniProtKB.::GO:0005770; C:late endosome; TAS:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; IMP:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; IMP:MGI. | | | | | | | | | | GO:0048870; P:cell motility; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060711; P:labyrinthine layer development; IMP:MGI.::GO:0060674; P:placenta blood vessel development; IMP:MGI.::GO:0045597; P:positive regulation of cell differentiation; IDA:MGI.::GO:2000641; P:regulation of early endosome to late endosome transport; TAS:UniProtKB.::GO:0090170; P:regulation of Golgi inheritance; TAS:UniProtKB.::GO:0032872; P:regulation of stress-activated MAPK cascade; TAS:UniProtKB. | 394 | Q28GW8 | 652 | MELK_XENTR Maternal embryonic leucine zipper ... | 268 | 4e-26 | 119 | 28 | 52 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 395 | Q69ZM6 | 1316 | STK36_MOUSE Serine/threonine-protein kinase 3... | 294 | 5e-26 | 120 | 29 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0042384; P:cilium assembly; IDA:UniProtKB.::GO:0007228; P:positive regulation of hh target transcription factor activity; IDA:UniProtKB.::GO:0045880; P:positive regulation of smoothened signaling pathway; IDA:UniProtKB.::GO:0009791; P:post-embryonic development; IMP:UniProtKB. | 396 | Q9JM01 | 593 | CDKL3_RAT Cyclin-dependent kinase-like 3 OS=R... | 293 | 5e-26 | 118 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 397 | P31749 | 480 | AKT1_HUMAN RAC-alpha serine/threonine-protein... | 276 | 5e-26 | 117 | 32 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0030235; F:nitric-oxide synthase regulator activity; IMP:BHF-UCL.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008633; P:activation of pro-apoptotic gene products; TAS:Reactome.::GO:0006924; P:activation-induced cell death of T cells; IMP:MGI.::GO:0008283; P:cell proliferation; TAS:UniProtKB.::GO:0031018; P:endocrine pancreas development; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008629; P:induction of apoptosis by intracellular signals; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; IMP:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0031999; P:negative regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006809; P:nitric oxide biosynthetic process; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0031659; P:positive regulation of cyclin-dependent protein kinase activity involved in G1/S; IDA:BHF-UCL.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0045600; P:positive regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:BHF-UCL.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:BHF-UCL.::GO:0051000; P:positive regulation of nitric-oxide synthase activity; IMP:BHF-UCL.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0000060; P:protein import into nucleus, translocation; IMP:UniProtKB.::GO:2001047; P:regulation of G1/S transition checkpoint; TAS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0034405; P:response to fluid shear stress; IMP:BHF-UCL.::GO:0009408; P:response to heat; TAS:ProtInc.::GO:0070141; P:response to UV-A; IDA:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome. | 398 | P34556 | 332 | CDK1_CAEEL Cyclin-dependent kinase 1 OS=Caeno... | 245 | 5e-26 | 115 | 30 | 54 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:WormBase.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IMP:UniProtKB.::GO:0040002; P:collagen and cuticulin-based cuticle development; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0045836; P:positive regulation of meiosis; IMP:WormBase.::GO:0051446; P:positive regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0035046; P:pronuclear migration; IMP:WormBase. | 399 | Q6BVA0 | 412 | IPL1_DEBHA Spindle assembly checkpoint kinase... | 288 | 5e-26 | 116 | 30 | 47 | GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW. | 400 | P39951 | 297 | CDK1_RAT Cyclin-dependent kinase 1 OS=Rattus ... | 302 | 6e-26 | 115 | 27 | 48 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030332; F:cyclin binding; IPI:RGD.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0035173; F:histone kinase activity; IDA:RGD.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007569; P:cell aging; IDA:RGD.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0070301; P:cellular response to hydrogen peroxide; IEP:RGD.::GO:0030261; P:chromosome condensation; IMP:RGD.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:RGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0031100; P:organ regeneration; IMP:RGD.::GO:0060045; P:positive regulation of cardiac muscle cell proliferation; IMP:RGD.::GO:0045740; P:positive regulation of DNA replication; IMP:RGD.::GO:0010628; P:positive regulation of gene expression; IMP:RGD.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:RGD.::GO:0033160; P:positive regulation of protein import into nucleus, translocation; IMP:RGD.::GO:0006461; P:protein complex assembly; IDA:RGD.::GO:0014823; P:response to activity; IEP:RGD.::GO:0014075; P:response to amine stimulus; IEP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0046688; P:response to copper ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IDA:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:RGD. | 401 | Q6X4A2 | 449 | CIPKV_ORYSJ CBL-interacting protein kinase 31... | 289 | 6e-26 | 116 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 402 | Q55FT4 | 2247 | TSUA_DICDI Probable serine/threonine-protein ... | 265 | 6e-26 | 120 | 29 | 50 | GO:0005881; C:cytoplasmic microtubule; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043326; P:chemotaxis to folate; IMP:dictyBase.::GO:0030010; P:establishment of cell polarity; IMP:dictyBase.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:dictyBase.::GO:0060176; P:regulation of aggregation involved in sorocarp development; IMP:dictyBase.::GO:0031272; P:regulation of pseudopodium assembly; IMP:dictyBase. | 403 | Q6GPL3 | 368 | AUKBB_XENLA Aurora kinase B-B OS=Xenopus laev... | 245 | 6e-26 | 115 | 32 | 49 | GO:0000785; C:chromatin; ISS:UniProtKB.::GO:0032133; C:chromosome passenger complex; ISS:UniProtKB.::GO:0000775; C:chromosome, centromeric region; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035175; F:histone kinase activity (H3-S10 specific); ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 404 | Q8K0D0 | 523 | CDK17_MOUSE Cyclin-dependent kinase 17 OS=Mus... | 295 | 6e-26 | 117 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 405 | Q9XT09 | 393 | MP2K1_PANTR Dual specificity mitogen-activate... | 309 | 7e-26 | 116 | 30 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 406 | Q9Z265 | 546 | CHK2_MOUSE Serine/threonine-protein kinase Ch... | 330 | 7e-26 | 117 | 27 | 46 | GO:0016605; C:PML body; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:UniProtKB.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0042176; P:regulation of protein catabolic process; ISS:UniProtKB.::GO:0010332; P:response to gamma radiation; IDA:MGI.::GO:0072428; P:signal transduction involved in intra-S DNA damage checkpoint; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 407 | Q8BRK8 | 552 | AAPK2_MOUSE 5'-AMP-activated protein kinase c... | 293 | 7e-26 | 117 | 30 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004679; F:AMP-activated protein kinase activity; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0035174; F:histone serine kinase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0006695; P:cholesterol biosynthetic process; IEA:UniProtKB-KW.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0055089; P:fatty acid homeostasis; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0032007; P:negative regulation of TOR signaling cascade; IMP:UniProtKB.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0045821; P:positive regulation of glycolysis; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:2000505; P:regulation of energy homeostasis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 408 | P54644 | 444 | KRAC_DICDI RAC family serine/threonine-protei... | 323 | 8e-26 | 116 | 28 | 49 | GO:0005938; C:cell cortex; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0019887; F:protein kinase regulator activity; TAS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; TAS:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:dictyBase.::GO:0031036; P:myosin II filament assembly; TAS:dictyBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:dictyBase.::GO:0045859; P:regulation of protein kinase activity; TAS:dictyBase. | 409 | Q98TY9 | 481 | AKT1_XENLA RAC-alpha serine/threonine-protein... | 276 | 8e-26 | 116 | 32 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 410 | Q55BN8 | 418 | NEK2_DICDI Probable serine/threonine-protein ... | 274 | 8e-26 | 116 | 33 | 49 | GO:0005813; C:centrosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase. | | | | | | | | | | GO:0007098; P:centrosome cycle; IMP:dictyBase. | 411 | Q94C40 | 432 | CIPKH_ARATH CBL-interacting serine/threonine-... | 274 | 8e-26 | 116 | 29 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 412 | Q04899 | 451 | CDK18_MOUSE Cyclin-dependent kinase 18 OS=Mus... | 302 | 9e-26 | 116 | 28 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 413 | Q6DE08 | 361 | AUKBA_XENLA Aurora kinase B-A OS=Xenopus laev... | 245 | 9e-26 | 115 | 32 | 49 | | | | | | | | | | | | | | | | | | | | | | 414 | Q922R0 | 355 | PRKX_MOUSE cAMP-dependent protein kinase cata... | 312 | 9e-26 | 115 | 30 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0001525; P:angiogenesis; IMP:UniProtKB.::GO:0031589; P:cell-substrate adhesion; ISS:UniProtKB.::GO:0043542; P:endothelial cell migration; ISS:UniProtKB.::GO:0001935; P:endothelial cell proliferation; IMP:UniProtKB.::GO:0060562; P:epithelial tube morphogenesis; ISS:UniProtKB.::GO:0060993; P:kidney morphogenesis; ISS:UniProtKB.::GO:0030099; P:myeloid cell differentiation; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB.::GO:2000696; P:regulation of epithelial cell differentiation involved in kidney development; ISS:UniProtKB. | 415 | A8XA58 | 326 | CDK1_CAEBR Cyclin-dependent kinase 1 OS=Caeno... | 245 | 9e-26 | 114 | 30 | 52 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051446; P:positive regulation of meiotic cell cycle; ISS:UniProtKB. | 416 | A2BD05 | 313 | NEK6_PIG Serine/threonine-protein kinase Nek6... | 259 | 1e-25 | 114 | 30 | 51 | GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0031572; P:G2/M transition DNA damage checkpoint; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 417 | P06493 | 297 | CDK1_HUMAN Cyclin-dependent kinase 1 OS=Homo ... | 302 | 1e-25 | 114 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005739; C:mitochondrion; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005876; C:spindle microtubule; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0007098; P:centrosome cycle; TAS:UniProtKB.::GO:0006281; P:DNA repair; TAS:UniProtKB.::GO:0006260; P:DNA replication; TAS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0007344; P:pronuclear fusion; TAS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0045995; P:regulation of embryonic development; TAS:UniProtKB.::GO:0014038; P:regulation of Schwann cell differentiation; TAS:UniProtKB.::GO:0000083; P:regulation of transcription involved in G1/S phase of mitotic cell cycle; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 418 | Q8SRF5 | 265 | Y823_ENCCU Probable cell division protein kin... | 213 | 1e-25 | 113 | 33 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 419 | Q8W490 | 470 | PEPK2_ARATH Serine/threonine-protein kinase P... | 304 | 1e-25 | 116 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 420 | P06245 | 380 | KAPB_YEAST cAMP-dependent protein kinase type... | 258 | 1e-25 | 115 | 30 | 48 | GO:0005952; C:cAMP-dependent protein kinase complex; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0001403; P:invasive growth in response to glucose limitation; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; ISS:SGD. | 421 | Q63796 | 888 | M3K12_RAT Mitogen-activated protein kinase ki... | 266 | 1e-25 | 119 | 29 | 50 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0016572; P:histone phosphorylation; ISS:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. |
