| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9FE17 | 473 | SIR1_ARATH NAD-dependent protein deacetylase ... | 173 | 0.00000003 | 60.5 | 31 | 45 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 92 | C6A243 | 255 | NPD_THESM NAD-dependent protein deacylase OS=... | 235 | 0.00000003 | 58.9 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 93 | Q9YB13 | 245 | NPD_AERPE NAD-dependent protein deacylase OS=... | 233 | 0.00000004 | 58.2 | 27 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 94 | Q9KEE5 | 237 | NPD_BACHD NAD-dependent protein deacetylase O... | 230 | 0.00000005 | 58.2 | 27 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 95 | Q8CJM9 | 241 | NPD2_STRCO NAD-dependent protein deacetylase ... | 225 | 0.00000005 | 57.8 | 25 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 96 | Q8ELR0 | 236 | NPD_OCEIH NAD-dependent protein deacetylase O... | 226 | 0.00000006 | 57.8 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 97 | Q9NRC8 | 400 | SIR7_HUMAN NAD-dependent protein deacetylase ... | 328 | 0.00000007 | 58.9 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; IDA:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007072; P:positive regulation of transcription on exit from mitosis; IMP:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; IMP:UniProtKB. | 98 | E2RDZ6 | 310 | SIR5_CANFA NAD-dependent protein deacylase si... | 240 | 0.00000008 | 58.2 | 28 | 42 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 99 | Q89EA6 | 273 | NPD2_BRAJA NAD-dependent protein deacetylase ... | 267 | 0.00000008 | 57.8 | 24 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 100 | P0CS88 | 354 | HST22_EMENI NAD-dependent protein deacetylase... | 230 | 0.00000009 | 58.5 | 29 | 45 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 101 | P66816 | 243 | NPD_STAAN NAD-dependent protein deacetylase O... | 235 | 0.0000001 | 57 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 102 | P66815 | 243 | NPD_STAAM NAD-dependent protein deacetylase O... | 235 | 0.0000001 | 57 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 103 | Q8F3Z6 | 246 | NPD_LEPIN NAD-dependent protein deacylase OS=... | 227 | 0.0000001 | 57 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 104 | Q72RR0 | 246 | NPD_LEPIC NAD-dependent protein deacylase OS=... | 227 | 0.0000001 | 57 | 24 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 105 | Q6GEN2 | 243 | NPD_STAAR NAD-dependent protein deacetylase O... | 235 | 0.0000002 | 56.6 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 106 | O28597 | 245 | NPD1_ARCFU NAD-dependent protein deacylase 1 ... | 230 | 0.0000002 | 56.6 | 26 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 107 | Q94AQ6 | 373 | SIR4_ARATH NAD-dependent protein deacetylase ... | 160 | 0.0000002 | 57.4 | 27 | 43 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042742; P:defense response to bacterium; IMP:TAIR.::GO:0031348; P:negative regulation of defense response; IMP:TAIR.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 108 | Q1JQC6 | 315 | SIR4_BOVIN NAD-dependent protein deacetylase ... | 159 | 0.0000002 | 57 | 29 | 46 | GO:0005759; C:mitochondrial matrix; IDA:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 109 | Q5HE07 | 243 | NPD_STAAC NAD-dependent protein deacetylase O... | 235 | 0.0000002 | 56.2 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 110 | Q3ZBQ0 | 310 | SIR5_BOVIN NAD-dependent protein deacylase si... | 234 | 0.0000002 | 56.6 | 28 | 41 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 111 | Q8NVC8 | 243 | NPD_STAAW NAD-dependent protein deacetylase O... | 235 | 0.0000003 | 55.8 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 112 | Q6G7B7 | 243 | NPD_STAAS NAD-dependent protein deacetylase O... | 235 | 0.0000003 | 55.8 | 25 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 113 | Q53700 | 243 | NPD_STAA8 NAD-dependent protein deacetylase O... | 235 | 0.0000003 | 55.8 | 26 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 114 | Q6N6U0 | 253 | NPD_RHOPA NAD-dependent protein deacetylase O... | 178 | 0.0000004 | 55.5 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 115 | Q8R216 | 333 | SIR4_MOUSE NAD-dependent protein deacetylase ... | 266 | 0.0000005 | 56.2 | 25 | 42 | GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro. | 116 | Q8BKJ9 | 402 | SIR7_MOUSE NAD-dependent protein deacetylase ... | 328 | 0.0000006 | 56.2 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005731; C:nucleolus organizer region; ISS:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007072; P:positive regulation of transcription on exit from mitosis; ISS:UniProtKB.::GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0009303; P:rRNA transcription; ISS:UniProtKB. | 117 | A9A0B2 | 273 | NPD_DESOH NAD-dependent protein deacylase OS=... | 243 | 0.0000006 | 55.5 | 27 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 118 | Q9UZE7 | 250 | NPD_PYRAB NAD-dependent protein deacylase OS=... | 244 | 0.0000008 | 54.7 | 24 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0017136; F:NAD-dependent histone deacetylase activity; IEA:HAMAP.::GO:0008270; F:zinc ion binding; IEA:HAMAP. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 119 | E1BRE2 | 309 | SIR5_CHICK NAD-dependent protein deacylase si... | 243 | 0.0000009 | 55.1 | 26 | 40 | | | | | | | | | | | GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0036054; F:protein-malonyllysine demalonylase activity; ISS:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | | 120 | Q8K2C6 | 310 | SIR5_MOUSE NAD-dependent protein deacylase si... | 235 | 0.0000009 | 55.1 | 27 | 40 | GO:0005758; C:mitochondrial intermembrane space; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0036054; F:protein-malonyllysine demalonylase activity; IMP:UniProtKB.::GO:0036055; F:protein-succinyllysine desuccinylase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; ISS:UniProtKB. | 121 | F7EZ75 | 310 | SIR5_MACMU NAD-dependent protein deacylase si... | 237 | 0.000001 | 54.3 | 27 | 41 | | | | | | | | | | | GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. |
