rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q99698 | 3801 | LYST_HUMAN Lysosomal-trafficking regulator OS... | 90 | 0.22 | 39.7 | 26 | 49 | GO:0015630; C:microtubule cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0042742; P:defense response to bacterium; ISS:UniProtKB.::GO:0042832; P:defense response to protozoan; ISS:UniProtKB.::GO:0051607; P:defense response to virus; ISS:UniProtKB.::GO:0032510; P:endosome to lysosome transport via multivesicular body sorting pathway; IMP:UniProtKB.::GO:0030595; P:leukocyte chemotaxis; ISS:UniProtKB.::GO:0033364; P:mast cell secretory granule organization; ISS:UniProtKB.::GO:0032438; P:melanosome organization; ISS:UniProtKB.::GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:UniProtKB. | 2 | P49918 | 316 | CDN1C_HUMAN Cyclin-dependent kinase inhibitor... | 52 | 7.3 | 33.9 | 38 | 54 | GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; TAS:ProtInc.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:ProtInc.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IMP:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc. |