| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40961 | 287 | PHB1_YEAST Prohibitin-1 OS=Saccharomyces cere... | 269 | 3e-138 | 398 | 73 | 86 | GO:0005743; C:mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007007; P:inner mitochondrial membrane organization; IMP:SGD.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0070584; P:mitochondrion morphogenesis; IMP:SGD.::GO:0045861; P:negative regulation of proteolysis; IPI:SGD.::GO:0006457; P:protein folding; IPI:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD. | 2 | Q9P7H3 | 282 | PHB1_SCHPO Prohibitin-1 OS=Schizosaccharomyce... | 264 | 2e-129 | 375 | 69 | 84 | GO:0005743; C:mitochondrial inner membrane; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0007007; P:inner mitochondrial membrane organization; ISS:PomBase.::GO:0000001; P:mitochondrion inheritance; ISS:PomBase.::GO:0006457; P:protein folding; ISS:PomBase. | 3 | P84173 | 272 | PHB_CHICK Prohibitin OS=Gallus gallus (Chicke... | 264 | 4e-106 | 316 | 58 | 77 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 4 | P24156 | 276 | L2CC_DROME Protein l(2)37Cc OS=Drosophila mel... | 260 | 8e-106 | 315 | 58 | 79 | GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0016020; C:membrane; IEA:InterPro.::GO:0005875; C:microtubule associated complex; IDA:FlyBase. | | | | | | | | | | | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 5 | Q54GI9 | 271 | PHB1_DICDI Prohibitin-1, mitochondrial OS=Dic... | 260 | 5e-105 | 313 | 56 | 77 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 6 | P67779 | 272 | PHB_RAT Prohibitin OS=Rattus norvegicus (Rat)... | 249 | 9e-105 | 312 | 58 | 80 | GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0008285; P:negative regulation of cell proliferation; IMP:RGD.::GO:0031100; P:organ regeneration; IEP:RGD.::GO:0001552; P:ovarian follicle atresia; IEP:RGD.::GO:0001541; P:ovarian follicle development; IEP:RGD.::GO:0034097; P:response to cytokine stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0006950; P:response to stress; IEP:RGD. | 7 | P67778 | 272 | PHB_MOUSE Prohibitin OS=Mus musculus (Mouse).... | 249 | 9e-105 | 312 | 58 | 80 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI. | | | | | | | | | | GO:0000981; F:sequence-specific DNA binding RNA polymerase II transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0071897; P:DNA biosynthetic process; IMP:MGI.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. | 8 | P35232 | 272 | PHB_HUMAN Prohibitin OS=Homo sapiens (Human).... | 249 | 4e-104 | 311 | 58 | 80 | GO:0005887; C:integral to plasma membrane; IDA:HGNC.::GO:0005743; C:mitochondrial inner membrane; TAS:UniProtKB.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL. | | | | | | | | | | GO:0071354; P:cellular response to interleukin-6; IDA:BHF-UCL.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0016575; P:histone deacetylation; IDA:UniProtKB.::GO:0060766; P:negative regulation of androgen receptor signaling pathway; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IMP:BHF-UCL.::GO:2000323; P:negative regulation of glucocorticoid receptor signaling pathway; IDA:BHF-UCL.::GO:0010944; P:negative regulation of transcription by competitive promoter binding; IDA:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0050847; P:progesterone receptor signaling pathway; IDA:BHF-UCL.::GO:0042981; P:regulation of apoptotic process; TAS:UniProtKB. | 9 | Q3T165 | 272 | PHB_BOVIN Prohibitin OS=Bos taurus (Bovine). ... | 249 | 4e-104 | 311 | 58 | 80 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 10 | Q9BKU4 | 275 | PHB1_CAEEL Mitochondrial prohibitin complex p... | 260 | 6e-103 | 308 | 58 | 78 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0030421; P:defecation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0070584; P:mitochondrion morphogenesis; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0002082; P:regulation of oxidative phosphorylation; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. | 11 | Q54Q31 | 293 | PHB2_DICDI Prohibitin-2 OS=Dictyostelium disc... | 248 | 9e-97 | 293 | 57 | 78 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 12 | P50085 | 310 | PHB2_YEAST Prohibitin-2 OS=Saccharomyces cere... | 234 | 4e-96 | 292 | 59 | 80 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0045861; P:negative regulation of proteolysis; IPI:SGD.::GO:0006457; P:protein folding; IDA:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD. | 13 | Q5XIH7 | 299 | PHB2_RAT Prohibitin-2 OS=Rattus norvegicus (R... | 271 | 8e-94 | 285 | 51 | 77 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 14 | O35129 | 299 | PHB2_MOUSE Prohibitin-2 OS=Mus musculus (Mous... | 271 | 9e-94 | 285 | 51 | 77 | GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060749; P:mammary gland alveolus development; IMP:MGI.::GO:0060744; P:mammary gland branching involved in thelarche; IMP:MGI.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:MGI.::GO:0033600; P:negative regulation of mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0060762; P:regulation of branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 15 | Q99623 | 299 | PHB2_HUMAN Prohibitin-2 OS=Homo sapiens (Huma... | 271 | 9e-94 | 285 | 51 | 77 | GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0030331; F:estrogen receptor binding; NAS:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 16 | Q5RB19 | 299 | PHB2_PONAB Prohibitin-2 OS=Pongo abelii (Suma... | 271 | 4e-93 | 284 | 51 | 76 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 17 | Q2HJ97 | 299 | PHB2_BOVIN Prohibitin-2 OS=Bos taurus (Bovine... | 271 | 6e-93 | 283 | 51 | 76 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 18 | A9UMS3 | 301 | PHB2_XENTR Prohibitin-2 OS=Xenopus tropicalis... | 258 | 8e-93 | 283 | 53 | 78 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 19 | O94550 | 288 | PHB2_SCHPO Prohibitin-2 OS=Schizosaccharomyce... | 234 | 2e-91 | 279 | 57 | 76 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0006457; P:protein folding; ISS:PomBase. | 20 | Q5ZMN3 | 301 | PHB2_CHICK Prohibitin-2 OS=Gallus gallus (Chi... | 266 | 5e-86 | 265 | 48 | 74 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004872; F:receptor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 21 | P50093 | 294 | PHB2_CAEEL Mitochondrial prohibitin complex p... | 238 | 3e-80 | 250 | 49 | 75 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030421; P:defecation; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0070584; P:mitochondrion morphogenesis; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0002082; P:regulation of oxidative phosphorylation; IMP:WormBase.::GO:0043051; P:regulation of pharyngeal pumping; IMP:WormBase.::GO:0006979; P:response to oxidative stress; IMP:WormBase.::GO:0007283; P:spermatogenesis; IMP:WormBase. | 22 | P86220 | 87 | PHB_MESAU Prohibitin OS=Mesocricetus auratus ... | 114 | 6e-16 | 75.1 | 42 | 54 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006260; P:DNA replication; IEA:UniProtKB-KW. | 23 | O28852 | 249 | Y1420_ARCFU Uncharacterized protein AF_1420 O... | 226 | 0.0008 | 43.5 | 24 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 24 | P44545 | 295 | HFLC_HAEIN Protein HflC OS=Haemophilus influe... | 271 | 0.009 | 40.4 | 23 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 25 | Q9FM19 | 286 | HIR1_ARATH Hypersensitive-induced response pr... | 181 | 0.074 | 37.7 | 23 | 43 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR. | | | | | | | | | | GO:0043424; F:protein histidine kinase binding; IPI:UniProtKB. | | | | | | | | | | | 26 | P02469 | 1786 | LAMB1_MOUSE Laminin subunit beta-1 OS=Mus mus... | 150 | 0.4 | 35.8 | 27 | 43 | GO:0005606; C:laminin-1 complex; IDA:MGI.::GO:0043259; C:laminin-10 complex; IPI:MGI.::GO:0005607; C:laminin-2 complex; ISS:HGNC.::GO:0043257; C:laminin-8 complex; ISS:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019899; F:enzyme binding; IPI:MGI.::GO:0005201; F:extracellular matrix structural constituent; ISS:HGNC.::GO:0043208; F:glycosphingolipid binding; IDA:MGI.::GO:0005178; F:integrin binding; IMP:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:MGI.::GO:0007566; P:embryo implantation; IMP:MGI.::GO:0007611; P:learning or memory; NAS:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0031175; P:neuron projection development; IDA:MGI.::GO:0042476; P:odontogenesis; ISS:HGNC.::GO:0030335; P:positive regulation of cell migration; ISS:HGNC. | 27 | P0ABC6 | 334 | HFLC_SHIFL Protein HflC OS=Shigella flexneri.... | 104 | 0.76 | 34.7 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 28 | P0ABC3 | 334 | HFLC_ECOLI Modulator of FtsH protease HflC OS... | 104 | 0.76 | 34.7 | 29 | 48 | GO:0071575; C:integral to external side of plasma membrane; IDA:EcoCyc. | | | | | | | | | | GO:0008233; F:peptidase activity; IEA:InterPro. | | | | | | | | | | GO:0048553; P:negative regulation of metalloenzyme activity; IGI:EcoCyc.::GO:0009408; P:response to heat; IEP:EcoCyc. | 29 | P0ABC4 | 334 | HFLC_ECOL6 Protein HflC OS=Escherichia coli O... | 104 | 0.76 | 34.7 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 30 | P0ABC5 | 334 | HFLC_ECO57 Protein HflC OS=Escherichia coli O... | 104 | 0.76 | 34.7 | 29 | 48 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008236; F:serine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 31 | B2A2I8 | 926 | SYI_NATTJ Isoleucine--tRNA ligase OS=JW/NM-WN... | 75 | 1.6 | 33.9 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004822; F:isoleucine-tRNA ligase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006428; P:isoleucyl-tRNA aminoacylation; IEA:InterPro. |
