rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
511 | P16152 | 277 | CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Ho... | 253 | 0.0002 | 45.8 | 28 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:UniProtKB.::GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB. | 512 | O16925 | 314 | STDH4_CAEEL Putative steroid dehydrogenase 4 ... | 181 | 0.0002 | 45.8 | 26 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 513 | P29147 | 343 | BDH_RAT D-beta-hydroxybutyrate dehydrogenase,... | 180 | 0.0002 | 45.8 | 28 | 48 | GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:RGD. | | | | | | | | | | GO:0060612; P:adipose tissue development; IEP:RGD.::GO:0007420; P:brain development; IEP:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0046686; P:response to cadmium ion; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0060416; P:response to growth hormone stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0042594; P:response to starvation; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 514 | Q8MI29 | 277 | CBR1_MACFA Carbonyl reductase [NADPH] 1 OS=Ma... | 203 | 0.0002 | 45.4 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 515 | Q6CHP1 | 389 | MKAR_YARLI 3-ketoacyl-CoA reductase OS=lipoly... | 192 | 0.0002 | 45.8 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 516 | Q6UX07 | 377 | DHR13_HUMAN Dehydrogenase/reductase SDR famil... | 128 | 0.0003 | 45.4 | 33 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 517 | P50172 | 292 | DHI1_MOUSE Corticosteroid 11-beta-dehydrogena... | 187 | 0.0003 | 45.1 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030324; P:lung development; IMP:MGI.::GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 518 | P59837 | 316 | RDH12_BOVIN Retinol dehydrogenase 12 OS=Bos t... | 156 | 0.0003 | 45.1 | 32 | 46 | GO:0005622; C:intracellular; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 519 | P55006 | 317 | RDH7_RAT Retinol dehydrogenase 7 OS=Rattus no... | 184 | 0.0003 | 45.1 | 28 | 44 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IEA:EC. | | | | | | | | | | | 520 | P38286 | 347 | MKAR_YEAST 3-ketoacyl-CoA reductase OS=Saccha... | 191 | 0.0003 | 45.1 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0045703; F:ketoreductase activity; IPI:SGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; IPI:SGD. | 521 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 151 | 0.0003 | 45.4 | 29 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 522 | A7TMJ2 | 347 | MKAR_VANPO 3-ketoacyl-CoA reductase OS=(Kluyv... | 190 | 0.0003 | 45.1 | 26 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 523 | P51976 | 406 | DHI2_RABIT Corticosteroid 11-beta-dehydrogena... | 185 | 0.0003 | 45.1 | 28 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 524 | Q03326 | 298 | OXIR_STRAT Probable oxidoreductase OS=Strepto... | 149 | 0.0004 | 44.7 | 33 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 525 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 187 | 0.0004 | 44.7 | 29 | 46 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 526 | Q320W2 | 240 | FOLM_SHIBS Dihydrofolate reductase folM OS=Sh... | 179 | 0.0004 | 44.7 | 25 | 44 | | | | | | | | | | | GO:0004146; F:dihydrofolate reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW. | 527 | Q5XGF7 | 341 | RDH10_XENTR Retinol dehydrogenase 10 OS=Xenop... | 203 | 0.0004 | 44.7 | 22 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 528 | Q8TC12 | 318 | RDH11_HUMAN Retinol dehydrogenase 11 OS=Homo ... | 235 | 0.0004 | 44.7 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:MGI.::GO:0042572; P:retinol metabolic process; ISS:UniProtKB.::GO:0008202; P:steroid metabolic process; TAS:Reactome. | 529 | Q5BL28 | 318 | DS7CB_DANRE Dehydrogenase/reductase SDR famil... | 182 | 0.0005 | 44.7 | 22 | 42 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 530 | O74959 | 339 | YJCD_SCHPO Uncharacterized oxidoreductase C73... | 161 | 0.0005 | 44.3 | 30 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 531 | P43066 | 281 | ARDH_CANAW D-arabinitol 2-dehydrogenase [ribu... | 191 | 0.0005 | 44.3 | 26 | 44 | | | | | | | | | | | GO:0047038; F:D-arabinitol 2-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; ISS:UniProtKB. | 532 | Q17QU7 | 377 | DHR13_BOVIN Dehydrogenase/reductase SDR famil... | 151 | 0.0005 | 44.3 | 33 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 533 | Q6DCT3 | 341 | RD10A_XENLA Retinol dehydrogenase 10-A OS=Xen... | 169 | 0.0005 | 44.3 | 24 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 534 | Q6P7J1 | 291 | DHI1A_XENLA Hydroxysteroid 11-beta-dehydrogen... | 178 | 0.0006 | 44.3 | 26 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 535 | O08699 | 266 | PGDH_RAT 15-hydroxyprostaglandin dehydrogenas... | 120 | 0.0006 | 43.9 | 29 | 50 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; IEP:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 536 | Q58NB6 | 319 | DHRS9_MOUSE Dehydrogenase/reductase SDR famil... | 180 | 0.0006 | 44.3 | 26 | 44 | GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005792; C:microsome; ISS:UniProtKB. | | | | | | | | | | GO:0004022; F:alcohol dehydrogenase (NAD) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; ISS:UniProtKB.::GO:0047035; F:testosterone dehydrogenase (NAD+) activity; ISS:UniProtKB. | | | | | | | | | | GO:0042904; P:9-cis-retinoic acid biosynthetic process; ISS:UniProtKB. | 537 | P37059 | 387 | DHB2_HUMAN Estradiol 17-beta-dehydrogenase 2 ... | 188 | 0.0006 | 44.3 | 28 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047006; F:17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity; TAS:BHF-UCL.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IDA:UniProtKB. | | | | | | | | | | GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. | 538 | Q6FRM0 | 352 | MKAR_CANGA 3-ketoacyl-CoA reductase OS=NRRL Y... | 104 | 0.0007 | 44.3 | 35 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 539 | Q5SS80 | 376 | DHR13_MOUSE Dehydrogenase/reductase SDR famil... | 128 | 0.0007 | 44.3 | 32 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 540 | A5WWC6 | 319 | HSDL1_DANRE Inactive hydroxysteroid dehydroge... | 174 | 0.0007 | 43.9 | 25 | 44 | GO:0005739; C:mitochondrion; IDA:ZFIN. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 541 | P51975 | 292 | DHI1_SHEEP Corticosteroid 11-beta-dehydrogena... | 142 | 0.0007 | 43.9 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. |