rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
361 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 150 | 0.0000003 | 54.7 | 31 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 362 | Q4JK73 | 300 | DHB11_MACFA Estradiol 17-beta-dehydrogenase 1... | 150 | 0.0000003 | 54.3 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 363 | P37058 | 310 | DHB3_HUMAN Testosterone 17-beta-dehydrogenase... | 180 | 0.0000003 | 54.3 | 27 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IEA:EC. | | | | | | | | | | GO:0006702; P:androgen biosynthetic process; TAS:Reactome.::GO:0030539; P:male genitalia development; TAS:ProtInc. | 364 | Q09517 | 316 | LE767_CAEEL Putative steroid dehydrogenase le... | 191 | 0.0000003 | 54.3 | 27 | 47 | GO:0045179; C:apical cortex; IDA:WormBase.::GO:0005783; C:endoplasmic reticulum; IDA:WormBase. | | | | | | | | | | GO:0050062; F:long-chain-fatty-acyl-CoA reductase activity; IDA:WormBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008210; P:estrogen metabolic process; IMP:WormBase.::GO:0030540; P:female genitalia development; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0032350; P:regulation of hormone metabolic process; IMP:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IDA:WormBase. | 365 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 177 | 0.0000003 | 53.9 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 366 | Q4X117 | 345 | MKAR_ASPFU 3-ketoacyl-CoA reductase OS=A1100)... | 187 | 0.0000003 | 54.3 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 367 | B0XSI3 | 345 | MKAR_ASPFC 3-ketoacyl-CoA reductase OS=(Asper... | 187 | 0.0000003 | 54.3 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 368 | P72220 | 277 | BPHB_PSEPU Cis-2,3-dihydrobiphenyl-2,3-diol d... | 275 | 0.0000003 | 53.9 | 27 | 43 | | | | | | | | | | | GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 369 | Q6QLL4 | 300 | DHI1_CAVPO Corticosteroid 11-beta-dehydrogena... | 186 | 0.0000003 | 53.9 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 370 | Q7M3I4 | 292 | DHI1_RABIT Corticosteroid 11-beta-dehydrogena... | 183 | 0.0000004 | 53.9 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; NAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:UniProtKB. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008211; P:glucocorticoid metabolic process; NAS:UniProtKB.] | 371 | Q556J2 | 334 | KDSR_DICDI 3-ketodihydrosphingosine reductase... | 192 | 0.0000004 | 53.9 | 28 | 43 | GO:0042406; C:extrinsic to endoplasmic reticulum membrane; ISS:dictyBase. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; ISS:dictyBase.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase. | 372 | P18297 | 262 | SPRE_RAT Sepiapterin reductase OS=Rattus norv... | 189 | 0.0000004 | 53.5 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010033; P:response to organic substance; IMP:RGD.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; IMP:RGD. | 373 | Q7Z5P4 | 300 | DHB13_HUMAN 17-beta-hydroxysteroid dehydrogen... | 158 | 0.0000004 | 53.9 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 374 | Q4P622 | 350 | MKAR_USTMA 3-ketoacyl-CoA reductase OS=Ustila... | 182 | 0.0000004 | 53.9 | 30 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 375 | P39644 | 259 | YWFH_BACSU Bacilysin biosynthesis oxidoreduct... | 270 | 0.0000005 | 53.5 | 21 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 376 | Q8NBQ5 | 300 | DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1... | 182 | 0.0000005 | 53.5 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 377 | Q59V93 | 349 | MKAR_CANAL 3-ketoacyl-CoA reductase OS=Candid... | 227 | 0.0000005 | 53.9 | 29 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 378 | P36086 | 256 | YKH1_YEAST Uncharacterized oxidoreductase YKL... | 192 | 0.0000005 | 53.1 | 30 | 46 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 379 | Q7RYE5 | 332 | MKAR_NEUCR 3-ketoacyl-CoA reductase OS=1257 /... | 182 | 0.0000005 | 53.5 | 27 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 380 | A4IFM3 | 313 | DR9C7_BOVIN Short-chain dehydrogenase/reducta... | 180 | 0.0000005 | 53.5 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 381 | Q9Z2M4 | 292 | DECR2_RAT Peroxisomal 2,4-dienoyl-CoA reducta... | 270 | 0.0000005 | 53.5 | 27 | 42 | GO:0005777; C:peroxisome; IDA:HGNC. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 382 | Q5NVG2 | 300 | DHB11_PONAB Estradiol 17-beta-dehydrogenase 1... | 182 | 0.0000006 | 53.5 | 27 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 383 | Q8KWS9 | 254 | BACC_BACAM Bacilysin biosynthesis oxidoreduct... | 270 | 0.0000006 | 53.1 | 21 | 42 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 384 | Q9Y394 | 339 | DHRS7_HUMAN Dehydrogenase/reductase SDR famil... | 149 | 0.0000006 | 53.5 | 29 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 385 | Q60V51 | 316 | LE767_CAEBR Putative steroid dehydrogenase le... | 191 | 0.0000006 | 53.1 | 26 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0030540; P:female genitalia development; ISS:UniProtKB.::GO:0042303; P:molting cycle; ISS:UniProtKB.::GO:0032350; P:regulation of hormone metabolic process; ISS:UniProtKB.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 386 | Q8BTX9 | 330 | HSDL1_MOUSE Inactive hydroxysteroid dehydroge... | 227 | 0.0000007 | 53.1 | 26 | 44 | GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 387 | Q5R9W5 | 414 | WWOX_PONAB WW domain-containing oxidoreductas... | 243 | 0.0000007 | 53.5 | 26 | 41 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 388 | Q6PUF4 | 287 | DHI1L_CHICK Hydroxysteroid 11-beta-dehydrogen... | 181 | 0.0000008 | 53.1 | 27 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 389 | A6SG70 | 331 | MKAR_BOTFB 3-ketoacyl-CoA reductase OS=cinere... | 180 | 0.0000008 | 53.1 | 28 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 390 | A8E5C5 | 324 | DS7CA_DANRE Dehydrogenase/reductase SDR famil... | 183 | 0.0000008 | 53.1 | 25 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 391 | A0R518 | 279 | Y6031_MYCS2 Putative short-chain type dehydro... | 208 | 0.0000009 | 52.8 | 28 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |