rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q6P3L6 | 319 | DH12A_DANRE Estradiol 17-beta-dehydrogenase 1... | 175 | 0.0000000003 | 63.2 | 32 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 242 | Q6QA33 | 311 | DH12B_DANRE Estradiol 17-beta-dehydrogenase 1... | 175 | 0.0000000003 | 63.2 | 32 | 53 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 243 | Q5M875 | 300 | DHB13_RAT 17-beta-hydroxysteroid dehydrogenas... | 156 | 0.0000000003 | 62.8 | 32 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 244 | Q5E9H7 | 312 | DHB12_BOVIN Estradiol 17-beta-dehydrogenase 1... | 193 | 0.0000000004 | 62.8 | 28 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 245 | A4QTE3 | 331 | MKAR_MAGO7 3-ketoacyl-CoA reductase OS=blast ... | 180 | 0.0000000004 | 62.8 | 31 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 246 | P39831 | 248 | YDFG_ECOLI NADP-dependent 3-hydroxy acid dehy... | 181 | 0.0000000004 | 62 | 29 | 45 | | | | | | | | | | | GO:0035527; F:3-hydroxypropionate dehydrogenase (NADP+) activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IDA:EcoCyc. | | | | | | | | | | GO:0006212; P:uracil catabolic process; IMP:EcoCyc. | 247 | B2B3L4 | 340 | MKAR_PODAN 3-ketoacyl-CoA reductase OS=(Pleur... | 181 | 0.0000000004 | 62.8 | 30 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 248 | Q8U8I2 | 249 | SDH_AGRT5 Serine 3-dehydrogenase OS=Agrobacte... | 189 | 0.0000000004 | 62 | 31 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 249 | Q92EK7 | 248 | Y452_LISIN Uncharacterized oxidoreductase Lin... | 192 | 0.0000000005 | 62 | 28 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 250 | P25145 | 248 | Y432_LISMO Uncharacterized oxidoreductase Lmo... | 192 | 0.0000000005 | 62 | 28 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 251 | Q7TS56 | 236 | CBR4_RAT Carbonyl reductase family member 4 O... | 261 | 0.0000000005 | 61.6 | 25 | 43 | GO:0005759; C:mitochondrial matrix; ISS:UniProtKB. | | | | | | | | | | GO:0070402; F:NADPH binding; ISS:UniProtKB.::GO:0008753; F:NADPH dehydrogenase (quinone) activity; ISS:UniProtKB.::GO:0048038; F:quinone binding; ISS:UniProtKB. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 252 | Q8X505 | 248 | YDFG_ECO57 NADP-dependent L-serine/L-allo-thr... | 181 | 0.0000000006 | 61.6 | 28 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 253 | Q83RE8 | 248 | YDFG_SHIFL NADP-dependent L-serine/L-allo-thr... | 181 | 0.0000000006 | 61.6 | 29 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 254 | Q6NUE2 | 236 | CBR4_XENLA Carbonyl reductase family member 4... | 179 | 0.0000000007 | 61.2 | 27 | 47 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 255 | Q7Q732 | 317 | DHRS7_ANOGA Dehydrogenase/reductase SDR famil... | 182 | 0.0000000007 | 62 | 27 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 256 | Q9N126 | 312 | RDH8_BOVIN Retinol dehydrogenase 8 OS=Bos tau... | 181 | 0.0000000007 | 62 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:InterPro.::GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; IEA:InterPro.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; IEA:UniProtKB-KW. | 257 | Q4R5G7 | 312 | DHB12_MACFA Estradiol 17-beta-dehydrogenase 1... | 193 | 0.0000000007 | 62 | 30 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 258 | Q8FHD2 | 248 | YDFG_ECOL6 NADP-dependent L-serine/L-allo-thr... | 181 | 0.0000000007 | 61.2 | 28 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 259 | Q2H1V7 | 342 | MKAR_CHAGB 3-ketoacyl-CoA reductase OS=6347 /... | 180 | 0.0000000008 | 62 | 31 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 260 | Q920N9 | 244 | DCXR_CAVPO L-xylulose reductase OS=Cavia porc... | 280 | 0.0000000008 | 61.2 | 26 | 41 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IDA:UniProtKB.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0005997; P:xylulose metabolic process; IDA:UniProtKB. | 261 | P08074 | 244 | CBR2_MOUSE Carbonyl reductase [NADPH] 2 OS=Mu... | 181 | 0.0000000008 | 61.2 | 30 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0043621; F:protein self-association; IDA:MGI. | | | | | | | | | | GO:0006116; P:NADH oxidation; TAS:MGI.::GO:0051262; P:protein tetramerization; IDA:MGI. | 262 | O00058 | 256 | MTDH_UROFA Probable NADP-dependent mannitol d... | 185 | 0.0000000008 | 61.2 | 28 | 47 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 263 | Q0IH28 | 323 | DRS7B_XENLA Dehydrogenase/reductase SDR famil... | 182 | 0.000000001 | 61.6 | 29 | 45 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 264 | Q7Z9I3 | 253 | YCP8_SCHPO Uncharacterized oxidoreductase C66... | 196 | 0.000000001 | 60.8 | 29 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase. | 265 | P51659 | 736 | DHB4_HUMAN Peroxisomal multifunctional enzyme... | 181 | 0.000000001 | 62.4 | 27 | 47 | GO:0005782; C:peroxisomal matrix; TAS:Reactome. | | | | | | | | | | GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; TAS:Reactome.::GO:0033989; F:3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.::GO:0016508; F:long-chain-enoyl-CoA hydratase activity; TAS:Reactome.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | GO:0008209; P:androgen metabolic process; IDA:UniProtKB.::GO:0006699; P:bile acid biosynthetic process; TAS:Reactome.::GO:0008210; P:estrogen metabolic process; IDA:UniProtKB.::GO:0033540; P:fatty acid beta-oxidation using acyl-CoA oxidase; TAS:Reactome. | 266 | O67505 | 270 | FABI_AQUAE Enoyl-[acyl-carrier-protein] reduc... | 280 | 0.000000001 | 61.2 | 24 | 42 | | | | | | | | | | | GO:0004318; F:enoyl-[acyl-carrier-protein reductase (NADH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.] | 267 | Q7FAE1 | 274 | MOMAS_ORYSJ Momilactone A synthase OS=Oryza s... | 276 | 0.000000001 | 60.8 | 26 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 268 | P66777 | 592 | EPHD_MYCTU Probable oxidoreductase ephD OS=My... | 185 | 0.000000001 | 61.6 | 30 | 45 | GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005887; C:integral to plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 269 | P66778 | 592 | EPHD_MYCBO Probable oxidoreductase ephD OS=My... | 185 | 0.000000001 | 61.6 | 30 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 270 | P00335 | 249 | RIDH_ENTAE Ribitol 2-dehydrogenase OS=Enterob... | 185 | 0.000000002 | 60.5 | 25 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050255; F:ribitol 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 271 | Q9KWN1 | 249 | SDH_RHIRD Serine 3-dehydrogenase OS=radiobact... | 189 | 0.000000002 | 60.1 | 30 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031132; F:serine 3-dehydrogenase activity; IEA:EC. | | | | | | | | | | |