| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q13191 | 982 | CBLB_HUMAN E3 ubiquitin-protein ligase CBL-B ... | 82 | 0.54 | 33.1 | 27 | 37 | | | | | | | | | | | | | | | | | | | | | | 2 | Q3TTA7 | 982 | CBLB_MOUSE E3 ubiquitin-protein ligase CBL-B ... | 82 | 0.57 | 33.1 | 27 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006955; P:immune response; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0046642; P:negative regulation of alpha-beta T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045732; P:positive regulation of protein catabolic process; IMP:MGI.::GO:0002669; P:positive regulation of T cell anergy; IMP:MGI.::GO:0042110; P:T cell activation; IMP:MGI. | 3 | Q6GQL0 | 918 | CBLBA_XENLA E3 ubiquitin-protein ligase CBL-B... | 82 | 0.6 | 33.1 | 27 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro. | 4 | Q8K4S7 | 938 | CBLB_RAT E3 ubiquitin-protein ligase CBL-B OS... | 82 | 0.6 | 33.1 | 27 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0023051; P:regulation of signaling; IEA:InterPro.::GO:0009629; P:response to gravity; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD. | 5 | P22681 | 906 | CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=... | 82 | 1.5 | 32 | 27 | 38 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC. | 6 | P22682 | 913 | CBL_MOUSE E3 ubiquitin-protein ligase CBL OS=... | 82 | 1.7 | 32 | 27 | 38 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045453; P:bone resorption; ISS:UniProtKB.::GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0006468; P:protein phosphorylation; ISS:UniProtKB. | 7 | Q9QUK0 | 568 | CDKL2_MOUSE Cyclin-dependent kinase-like 2 OS... | 38 | 3.1 | 31.2 | 42 | 55 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 8 | P31052 | 478 | DLDH2_PSEPU Dihydrolipoamide dehydrogenase OS... | 28 | 6.8 | 30 | 43 | 61 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004148; F:dihydrolipoyl dehydrogenase activity; IEA:EC.::GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW. | 9 | Q01085 | 375 | TIAR_HUMAN Nucleolysin TIAR OS=Homo sapiens (... | 50 | 7.7 | 29.6 | 40 | 56 | GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; TAS:ProtInc. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006952; P:defense response; TAS:ProtInc.::GO:0006917; P:induction of apoptosis; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc. |
