| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P38225 | 669 | FAT1_YEAST Very long-chain fatty acid transpo... | 602 | 3e-124 | 389 | 37 | 54 | GO:0005783; C:endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031235; C:intrinsic to internal side of plasma membrane; IDA:SGD.::GO:0005811; C:lipid particle; IDA:SGD.::GO:0005777; C:peroxisome; IMP:SGD. | | | | | | | | | | GO:0005324; F:long-chain fatty acid transporter activity; IMP:SGD.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IMP:SGD. | | | | | | | | | | GO:0000038; P:very long-chain fatty acid metabolic process; IMP:SGD. | 2 | O42633 | 643 | FAT1_COCHE Fatty acid transporter protein OS=... | 630 | 1e-112 | 358 | 35 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro. | | | | | | | | | | GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 3 | O14975 | 620 | S27A2_HUMAN Very long-chain acyl-CoA syntheta... | 587 | 2e-104 | 336 | 35 | 54 | GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005779; C:integral to peroxisomal membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0050197; F:phytanate-CoA ligase activity; IDA:UniProtKB.::GO:0070251; F:pristanate-CoA ligase activity; IDA:UniProtKB.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0001561; P:fatty acid alpha-oxidation; IDA:UniProtKB.::GO:0006635; P:fatty acid beta-oxidation; IDA:UniProtKB.::GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.::GO:0097089; P:methyl-branched fatty acid metabolic process; IDA:UniProtKB. | 4 | Q9Y2P4 | 619 | S27A6_HUMAN Long-chain fatty acid transport p... | 658 | 4e-102 | 330 | 34 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.::GO:0055085; P:transmembrane transport; TAS:Reactome.::GO:0000038; P:very long-chain fatty acid metabolic process; TAS:ProtInc. | 5 | O35488 | 620 | S27A2_MOUSE Very long-chain acyl-CoA syntheta... | 588 | 8e-101 | 327 | 35 | 52 | GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005792; C:microsome; IMP:MGI.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015245; F:fatty acid transporter activity; IDA:MGI.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:MGI. | | | | | | | | | | GO:0042760; P:very long-chain fatty acid catabolic process; IMP:MGI. | 6 | Q4R3Y4 | 643 | S27A4_MACFA Long-chain fatty acid transport p... | 661 | 3e-99 | 323 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 7 | P97524 | 620 | S27A2_RAT Very long-chain acyl-CoA synthetase... | 583 | 8e-99 | 321 | 35 | 53 | GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005779; C:integral to peroxisomal membrane; ISS:UniProtKB.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 8 | Q6P1M0 | 643 | S27A4_HUMAN Long-chain fatty acid transport p... | 661 | 4e-98 | 320 | 34 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015245; F:fatty acid transporter activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0044539; P:long-chain fatty acid import; IDA:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 9 | Q5RDY4 | 643 | S27A4_PONAB Long-chain fatty acid transport p... | 653 | 1e-97 | 318 | 34 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 10 | Q91VE0 | 643 | S27A4_MOUSE Long-chain fatty acid transport p... | 572 | 7e-95 | 311 | 36 | 51 | GO:0031526; C:brush border membrane; IDA:MGI.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005902; C:microvillus; IDA:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:MGI. | | | | | | | | | | GO:0015909; P:long-chain fatty acid transport; IMP:MGI.::GO:0001579; P:medium-chain fatty acid transport; IDA:MGI.::GO:0043588; P:skin development; IMP:MGI.::GO:0042760; P:very long-chain fatty acid catabolic process; IDA:MGI. | 11 | Q5K4L6 | 730 | S27A3_HUMAN Long-chain fatty acid transport p... | 544 | 2e-92 | 307 | 36 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 12 | Q60714 | 646 | S27A1_MOUSE Long-chain fatty acid transport p... | 568 | 4e-91 | 301 | 37 | 54 | GO:0031410; C:cytoplasmic vesicle; TAS:MGI.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015245; F:fatty acid transporter activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:MGI. | | | | | | | | | | GO:0033211; P:adiponectin-mediated signaling pathway; IMP:MGI.::GO:0001676; P:long-chain fatty acid metabolic process; TAS:MGI.::GO:0015909; P:long-chain fatty acid transport; IMP:MGI.::GO:0031652; P:positive regulation of heat generation; IMP:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; IMP:MGI.::GO:0009409; P:response to cold; IMP:MGI.::GO:0032868; P:response to insulin stimulus; IMP:MGI. | 13 | O88561 | 667 | S27A3_MOUSE Long-chain fatty acid transport p... | 546 | 1e-89 | 298 | 37 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI. | | | | | | | | | | GO:0004321; F:fatty-acyl-CoA synthase activity; IMP:MGI.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:MGI.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006637; P:acyl-CoA metabolic process; IC:MGI.::GO:0001676; P:long-chain fatty acid metabolic process; TAS:MGI. | 14 | P97849 | 646 | S27A1_RAT Long-chain fatty acid transport pro... | 552 | 8e-89 | 295 | 37 | 53 | GO:0005901; C:caveola; IDA:RGD.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD. | | | | | | | | | | GO:0015245; F:fatty acid transporter activity; NAS:RGD.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 15 | Q6PCB7 | 646 | S27A1_HUMAN Long-chain fatty acid transport p... | 551 | 9e-88 | 293 | 36 | 53 | GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032049; P:cardiolipin biosynthetic process; IMP:UniProtKB.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0015909; P:long-chain fatty acid transport; TAS:Reactome.::GO:0071072; P:negative regulation of phospholipid biosynthetic process; IMP:UniProtKB.::GO:0006654; P:phosphatidic acid biosynthetic process; IMP:UniProtKB.::GO:0006656; P:phosphatidylcholine biosynthetic process; IMP:UniProtKB.::GO:0006646; P:phosphatidylethanolamine biosynthetic process; IMP:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IMP:UniProtKB.::GO:0006659; P:phosphatidylserine biosynthetic process; IMP:UniProtKB.::GO:0055085; P:transmembrane transport; TAS:Reactome. | 16 | Q3ZKN0 | 646 | S27A1_BOVIN Long-chain fatty acid transport p... | 561 | 5e-87 | 291 | 37 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0006869; P:lipid transport; IEA:UniProtKB-KW. | 17 | Q4LDG0 | 689 | S27A5_MOUSE Bile acyl-CoA synthetase OS=Mus m... | 520 | 2e-82 | 280 | 35 | 50 | GO:0009925; C:basal plasma membrane; IDA:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047747; F:cholate-CoA ligase activity; IEA:EC.::GO:0015245; F:fatty acid transporter activity; IDA:MGI.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; TAS:MGI. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; IMP:MGI.::GO:0046951; P:ketone body biosynthetic process; IMP:MGI.::GO:0001676; P:long-chain fatty acid metabolic process; TAS:MGI.::GO:0015911; P:plasma membrane long-chain fatty acid transport; IMP:MGI.::GO:0006642; P:triglyceride mobilization; IMP:MGI. | 18 | Q9ES38 | 690 | S27A5_RAT Bile acyl-CoA synthetase OS=Rattus ... | 505 | 1e-81 | 277 | 35 | 50 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047747; F:cholate-CoA ligase activity; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD. | | | | | | | | | | GO:0008206; P:bile acid metabolic process; IMP:RGD.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 19 | Q9Y2P5 | 690 | S27A5_HUMAN Bile acyl-CoA synthetase OS=Homo ... | 547 | 9e-81 | 275 | 36 | 50 | GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047747; F:cholate-CoA ligase activity; IEA:EC.::GO:0031957; F:very long-chain fatty acid-CoA ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.::GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0000038; P:very long-chain fatty acid metabolic process; IDA:UniProtKB. | 20 | B2HHZ8 | 503 | FAC17_MYCMM Long-chain-fatty-acid--CoA ligase... | 543 | 1e-35 | 144 | 27 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:EC. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 21 | O53551 | 502 | FAC17_MYCTU Long-chain-fatty-acid--CoA ligase... | 437 | 4e-32 | 133 | 30 | 42 | GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; IDA:MTBBASE. | | | | | | | | | | GO:0042759; P:long-chain fatty acid biosynthetic process; IDA:MTBBASE. | 22 | Q7TWC5 | 502 | FAC17_MYCBO Long-chain-fatty-acid--CoA ligase... | 437 | 4e-32 | 133 | 30 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004467; F:long-chain fatty acid-CoA ligase activity; IEA:EC. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW. | 23 | Q8Z9L4 | 517 | CAIC_SALTI Probable crotonobetaine/carnitine-... | 514 | 7e-32 | 133 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 24 | B4T6J6 | 517 | CAIC_SALNS Probable crotonobetaine/carnitine-... | 514 | 8e-32 | 133 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 25 | B4TWR4 | 517 | CAIC_SALSV Probable crotonobetaine/carnitine-... | 514 | 8e-32 | 132 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 26 | B5FHG5 | 517 | CAIC_SALDC Probable crotonobetaine/carnitine-... | 514 | 9e-32 | 132 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 27 | Q8ZRX4 | 517 | CAIC_SALTY Probable crotonobetaine/carnitine-... | 514 | 3e-31 | 131 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 28 | B4TIH0 | 517 | CAIC_SALHS Probable crotonobetaine/carnitine-... | 514 | 3e-31 | 131 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 29 | A9MYJ6 | 517 | CAIC_SALPB Probable crotonobetaine/carnitine-... | 514 | 6e-31 | 130 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 30 | B5R1R0 | 517 | CAIC_SALEP Probable crotonobetaine/carnitine-... | 514 | 6e-31 | 130 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | | 31 | Q57TJ0 | 517 | CAIC_SALCH Probable crotonobetaine/carnitine-... | 514 | 6e-31 | 130 | 25 | 41 | | | | | | | | | | | GO:0016878; F:acid-thiol ligase activity; IEA:InterPro. | | | | | | | | | | |
