rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q6NS38 | 261 | ALKB2_HUMAN Alpha-ketoglutarate-dependent dio... | 162 | 0.00000000000003 | 77.8 | 31 | 44 | GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; IDA:UniProtKB.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.::GO:0008198; F:ferrous iron binding; IDA:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0035511; P:oxidative DNA demethylation; IDA:UniProtKB. | 2 | Q6P6J4 | 239 | ALKB2_MOUSE Alpha-ketoglutarate-dependent dio... | 162 | 0.00000000000003 | 77.8 | 30 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; ISS:UniProtKB.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035511; P:oxidative DNA demethylation; ISS:UniProtKB. | 3 | Q58DM4 | 278 | ALKB2_BOVIN Alpha-ketoglutarate-dependent dio... | 162 | 0.00000000000008 | 76.6 | 30 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; ISS:UniProtKB.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035511; P:oxidative DNA demethylation; ISS:UniProtKB. | 4 | Q32L00 | 286 | ALKB3_BOVIN Alpha-ketoglutarate-dependent dio... | 237 | 0.00000004 | 59.3 | 27 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; ISS:UniProtKB. | 5 | Q5XIC8 | 295 | ALKB3_RAT Alpha-ketoglutarate-dependent dioxy... | 217 | 0.0000001 | 58.2 | 26 | 39 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; ISS:UniProtKB. | 6 | Q5UQK2 | 191 | YR406_MIMIV Uncharacterized protein R406 OS=A... | 73 | 0.0000006 | 54.3 | 38 | 60 | | | | | | | | | | | GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro. | | | | | | | | | | | 7 | Q8K1E6 | 286 | ALKB3_MOUSE Alpha-ketoglutarate-dependent dio... | 218 | 0.000003 | 53.9 | 26 | 37 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051747; F:cytosine C-5 DNA demethylase activity; IDA:MGI.::GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; ISS:UniProtKB.::GO:0008198; F:ferrous iron binding; ISS:UniProtKB.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; ISS:UniProtKB. | 8 | Q96Q83 | 286 | ALKB3_HUMAN Alpha-ketoglutarate-dependent dio... | 218 | 0.000003 | 53.5 | 26 | 39 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0043734; F:DNA-N1-methyladenine dioxygenase activity; IDA:UniProtKB.::GO:0008198; F:ferrous iron binding; IDA:UniProtKB.::GO:0031418; F:L-ascorbic acid binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0035552; P:oxidative single-stranded DNA demethylation; IDA:UniProtKB. | 9 | P0ADI7 | 188 | YECD_ECOLI Isochorismatase family protein yec... | 104 | 0.000007 | 51.2 | 31 | 44 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 10 | P0ADI8 | 188 | YECD_ECO57 Uncharacterized isochorismatase fa... | 104 | 0.000007 | 51.2 | 31 | 44 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | P53184 | 216 | PNC1_YEAST Nicotinamidase OS=Saccharomyces ce... | 216 | 0.00004 | 49.3 | 27 | 39 | GO:0005634; C:nucleus; IDA:SGD.::GO:0005777; C:peroxisome; IDA:SGD. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008936; F:nicotinamidase activity; IMP:SGD. | | | | | | | | | | GO:0000183; P:chromatin silencing at rDNA; IMP:SGD.::GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0019363; P:pyridine nucleotide biosynthetic process; IEA:UniProtKB-KW.::GO:0001302; P:replicative cell aging; IEP:SGD. | 12 | Q51518 | 207 | PHZA_PSECL Probable isochorismatase OS=Pseudo... | 73 | 0.001 | 45.1 | 33 | 51 | | | | | | | | | | | GO:0008908; F:isochorismatase activity; IEA:EC. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 13 | P0C6D3 | 293 | VIBB_VIBCH Vibriobactin-specific isochorismat... | 88 | 0.002 | 44.7 | 33 | 47 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0008908; F:isochorismatase activity; IEA:EC. | | | | | | | | | | | 14 | A5F3F4 | 293 | VIBB_VIBC3 Vibriobactin-specific isochorismat... | 88 | 0.002 | 44.7 | 33 | 47 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0008908; F:isochorismatase activity; IEA:EC. | | | | | | | | | | | 15 | Q32KX0 | 204 | ISOC2_BOVIN Isochorismatase domain-containing... | 68 | 0.005 | 43.1 | 38 | 51 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro. | | | | | | | | | | | 16 | Q51790 | 207 | PHZD_PSEFL Probable isochorismatase OS=Pseudo... | 73 | 0.008 | 42.7 | 32 | 51 | | | | | | | | | | | GO:0008908; F:isochorismatase activity; IEA:EC. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. | 17 | P94573 | 189 | YWOC_BACSU Uncharacterized isochorismatase fa... | 126 | 0.014 | 41.6 | 26 | 39 | | | | | | | | | | | GO:0008908; F:isochorismatase activity; IEA:InterPro. | | | | | | | | | | | 18 | Q9A4N5 | 225 | RUTB_CAUCR Peroxyureidoacrylate/ureidoacrylat... | 255 | 0.016 | 42 | 25 | 37 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:EC. | | | | | | | | | | | 19 | B8H1Q1 | 238 | RUTB_CAUCN Peroxyureidoacrylate/ureidoacrylat... | 255 | 0.017 | 42 | 25 | 37 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:EC. | | | | | | | | | | | 20 | A8IAC9 | 227 | RUTB_AZOC5 Peroxyureidoacrylate/ureidoacrylat... | 89 | 0.064 | 40 | 30 | 45 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:EC. | | | | | | | | | | | 21 | P45743 | 312 | DHBB_BACSU Isochorismatase OS=Bacillus subtil... | 106 | 0.092 | 40 | 27 | 42 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0008908; F:isochorismatase activity; IEA:EC. | | | | | | | | | | | 22 | P85094 | 206 | ISC2A_MOUSE Isochorismatase domain-containing... | 67 | 0.16 | 38.5 | 36 | 49 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro. | | | | | | | | | | | 23 | B0SW60 | 233 | RUTB_CAUSK Peroxyureidoacrylate/ureidoacrylat... | 88 | 0.16 | 38.9 | 32 | 43 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:EC. | | | | | | | | | | | 24 | Q5RC03 | 205 | ISOC2_PONAB Isochorismatase domain-containing... | 68 | 0.27 | 37.7 | 34 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro. | | | | | | | | | | | 25 | Q6DF67 | 205 | ISOC2_XENTR Isochorismatase domain-containing... | 69 | 0.28 | 37.7 | 32 | 51 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro. | | | | | | | | | | | 26 | Q5PQ71 | 205 | ISOC2_XENLA Isochorismatase domain-containing... | 68 | 0.28 | 37.7 | 32 | 50 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro. | | | | | | | | | | | 27 | P96654 | 180 | YDDQ_BACSU Uncharacterized isochorismatase fa... | 63 | 2.3 | 34.7 | 27 | 49 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | D5VGV1 | 239 | RUTB_CAUST Peroxyureidoacrylate/ureidoacrylat... | 88 | 0.33 | 37.7 | 32 | 42 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:EC. | | | | | | | | | | | 29 | B1M6B8 | 258 | RUTB_METRJ Peroxyureidoacrylate/ureidoacrylat... | 108 | 0.37 | 37.7 | 31 | 41 | | | | | | | | | | | GO:0016811; F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; IEA:EC. | | | | | | | | | | | 30 | P74965 | 295 | VENB_VIBVU Probable isochorismatase OS=Vibrio... | 85 | 0.37 | 37.7 | 29 | 44 | | | | | | | | | | | GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0008908; F:isochorismatase activity; IEA:EC. | | | | | | | | | | | 31 | Q96AB3 | 205 | ISOC2_HUMAN Isochorismatase domain-containing... | 68 | 0.39 | 37.4 | 34 | 49 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0003824; F:catalytic activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:BHF-UCL. | | | | | | | | | | GO:0031648; P:protein destabilization; IMP:BHF-UCL. |