rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | B0M0P8 | 2356 | GEFL_DICDI Ras guanine nucleotide exchange fa... | 116 | 0.002 | 44.3 | 28 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.::GO:0017048; F:Rho GTPase binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.::GO:0046956; P:positive phototaxis; IMP:dictyBase.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0043052; P:thermotaxis; IMP:dictyBase. | 2 | Q3TX51 | 367 | LRC28_MOUSE Leucine-rich repeat-containing pr... | 178 | 4e-17 | 86.3 | 34 | 50 | | | | | | | | | | | | | | | | | | | | | | 3 | Q6GLE8 | 367 | LRC28_XENTR Leucine-rich repeat-containing pr... | 128 | 3.8 | 33.5 | 30 | 49 | | | | | | | | | | | | | | | | | | | | | | 4 | Q32KX5 | 367 | LRC28_BOVIN Leucine-rich repeat-containing pr... | 231 | 0.000000000000001 | 81.6 | 32 | 47 | | | | | | | | | | | | | | | | | | | | | | 5 | Q86X40 | 367 | LRC28_HUMAN Leucine-rich repeat-containing pr... | 231 | 0.000000000000005 | 80.1 | 31 | 47 | | | | | | | | | | | | | | | | | | | | | | 6 | Q9Y4C4 | 1052 | MFHA1_HUMAN Malignant fibrous histiocytoma-am... | 183 | 0.000009 | 52 | 27 | 40 | | | | | | | | | | | | | | | | | | | | | | 7 | Q5E9C0 | 277 | RSU1_BOVIN Ras suppressor protein 1 OS=Bos ta... | 75 | 0.00004 | 48.9 | 36 | 52 | | | | | | | | | | | | | | | | | | | | | | 8 | Q15404 | 277 | RSU1_HUMAN Ras suppressor protein 1 OS=Homo s... | 82 | 0.0001 | 47.8 | 33 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome. | 9 | Q01730 | 277 | RSU1_MOUSE Ras suppressor protein 1 OS=Mus mu... | 184 | 0.000000000002 | 71.2 | 32 | 46 | | | | | | | | | | | | | | | | | | | | | | 10 | Q6GPJ5 | 605 | LRC40_XENLA Leucine-rich repeat-containing pr... | 80 | 0.41 | 37 | 28 | 53 | | | | | | | | | | | | | | | | | | | | | | 11 | Q3V1N1 | 1048 | MFHA1_MOUSE Malignant fibrous histiocytoma-am... | 159 | 0.00003 | 50.1 | 29 | 45 | | | | | | | | | | | | | | | | | | | | | | 12 | Q6DHL5 | 238 | LRC57_DANRE Leucine-rich repeat-containing pr... | 165 | 0.0009 | 44.3 | 27 | 44 | | | | | | | | | | | | | | | | | | | | | | 13 | Q5M8G4 | 605 | LRC40_XENTR Leucine-rich repeat-containing pr... | 136 | 0.015 | 41.6 | 26 | 43 | | | | | | | | | | | | | | | | | | | | | | 14 | Q96DD0 | 335 | LRC39_HUMAN Leucine-rich repeat-containing pr... | 144 | 0.00007 | 48.5 | 28 | 47 | | | | | | | | | | | | | | | | | | | | | | 15 | Q7L1W4 | 858 | LRC8D_HUMAN Leucine-rich repeat-containing pr... | 132 | 0.0002 | 47.8 | 30 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 16 | Q8BGR2 | 859 | LRC8D_MOUSE Leucine-rich repeat-containing pr... | 202 | 2.4 | 34.7 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 17 | Q5U308 | 858 | LRC8D_RAT Leucine-rich repeat-containing prot... | 202 | 5.2 | 33.5 | 23 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 18 | Q8IWT6 | 810 | LRC8A_HUMAN Leucine-rich repeat-containing pr... | 127 | 0.38 | 37 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0002329; P:pre-B cell differentiation; ISS:UniProtKB. | 19 | Q8BXA7 | 1320 | PHLP2_MOUSE PH domain leucine-rich repeat-con... | 107 | 3.1 | 34.3 | 26 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 20 | O61967 | 699 | LAP1_CAEEL Protein lap1 OS=Caenorhabditis ele... | 130 | 1.7 | 35 | 28 | 41 | GO:0005912; C:adherens junction; IDA:UniProtKB.::GO:0016323; C:basolateral plasma membrane; IDA:WormBase. | | | | | | | | | | | | | | | | | | | | GO:0030029; P:actin filament-based process; IMP:WormBase.::GO:0007155; P:cell adhesion; IMP:WormBase.::GO:0007043; P:cell-cell junction assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IEP:UniProtKB.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0030728; P:ovulation; IMP:WormBase.::GO:0060465; P:pharynx development; IMP:WormBase.::GO:0015031; P:protein transport; IEP:UniProtKB.::GO:0045108; P:regulation of intermediate filament polymerization or depolymerization; IMP:UniProtKB. | 21 | Q8BGI7 | 337 | LRC39_MOUSE Leucine-rich repeat-containing pr... | 151 | 0.00000000006 | 67.4 | 31 | 49 | | | | | | | | | | | | | | | | | | | | | | 22 | Q4V8I7 | 810 | LRC8A_RAT Leucine-rich repeat-containing prot... | 127 | 1.7 | 35 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0002329; P:pre-B cell differentiation; ISS:UniProtKB. | 23 | Q80WG5 | 810 | LRC8A_MOUSE Leucine-rich repeat-containing pr... | 127 | 2.2 | 34.7 | 28 | 43 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0002329; P:pre-B cell differentiation; IMP:UniProtKB. | 24 | Q7KRY7 | 1851 | LAP4_DROME Protein lap4 OS=Drosophila melanog... | 74 | 0.004 | 43.5 | 32 | 53 | GO:0016323; C:basolateral plasma membrane; IDA:FlyBase.::GO:0005576; C:extracellular region; IDA:UniProtKB.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0016328; C:lateral plasma membrane; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0005918; C:septate junction; IDA:FlyBase.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005179; F:hormone activity; IDA:UniProtKB. | | | | | | | | | | GO:0030714; P:anterior/posterior axis specification, follicular epithelium; IMP:BHF-UCL.::GO:0022402; P:cell cycle process; IMP:FlyBase.::GO:0060581; P:cell fate commitment involved in pattern specification; IMP:BHF-UCL.::GO:0001708; P:cell fate specification; IMP:BHF-UCL.::GO:0000902; P:cell morphogenesis; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0045198; P:establishment of epithelial cell apical/basal polarity; IMP:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; TAS:FlyBase.::GO:0016336; P:establishment or maintenance of polarity of larval imaginal disc epithelium; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:FlyBase.::GO:0045571; P:negative regulation of imaginal disc growth; IMP:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0042048; P:olfactory behavior; IMP:FlyBase.::GO:0007318; P:pole plasm protein localization; IMP:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; IDA:UniProtKB.::GO:0007464; P:R3/R4 cell fate commitment; IMP:FlyBase.::GO:0051726; P:regulation of cell cycle; NAS:FlyBase.::GO:0030100; P:regulation of endocytosis; IMP:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:BHF-UCL.::GO:0046425; P:regulation of JAK-STAT cascade; IMP:BHF-UCL.::GO:0008593; P:regulation of Notch signaling pathway; IMP:BHF-UCL.::GO:0050803; P:regulation of synapse structure and activity; IMP:FlyBase.::GO:0007608; P:sensory perception of smell; IEA:UniProtKB-KW.::GO:0019991; P:septate junction assembly; IMP:FlyBase.::GO:0048863; P:stem cell differentiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase.::GO:0045186; P:zonula adherens assembly; IMP:FlyBase. | 25 | Q9V780 | 849 | LAP1_DROME Protein lap1 OS=Drosophila melanog... | 187 | 0.007 | 42.7 | 26 | 45 | GO:0005912; C:adherens junction; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0015031; P:protein transport; ISS:UniProtKB. | 26 | Q80VQ1 | 524 | LRRC1_MOUSE Leucine-rich repeat-containing pr... | 103 | 0.051 | 39.7 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 27 | A6H6A4 | 596 | LRIQ4_MOUSE Leucine-rich repeat and IQ domain... | 212 | 0.004 | 43.5 | 24 | 41 | | | | | | | | | | | | | | | | | | | | | | 28 | Q22875 | 559 | SHOC2_CAEEL Leucine-rich repeat protein soc-2... | 168 | 0.23 | 37.7 | 21 | 38 | | | | | | | | | | | | | | | | | | | | | GO:0008543; P:fibroblast growth factor receptor signaling pathway; IGI:WormBase.::GO:0007517; P:muscle organ development; IMP:WormBase.::GO:0046579; P:positive regulation of Ras protein signal transduction; IMP:UniProtKB.::GO:0031344; P:regulation of cell projection organization; IMP:WormBase.::GO:0040025; P:vulval development; IMP:UniProtKB. | 29 | Q8C0R9 | 853 | LRRD1_MOUSE Leucine-rich repeat and death dom... | 161 | 0.38 | 37 | 29 | 45 | | | | | | | | | | | | | | | | | | | | | | 30 | Q9BTT6 | 524 | LRRC1_HUMAN Leucine-rich repeat-containing pr... | 103 | 0.041 | 40 | 28 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 31 | Q6INV3 | 238 | LRC57_XENLA Leucine-rich repeat-containing pr... | 180 | 0.0000000004 | 63.5 | 27 | 48 | | | | | | | | | | | | | | | | | | | | | |