rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P47125 | 453 | I23O_YEAST Indoleamine 2,3-dioxygenase family... | 294 | 1e-74 | 243 | 48 | 61 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; NAS:SGD.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; NAS:SGD. | | | | | | | | | | GO:0034354; P:de novo NAD biosynthetic process from tryptophan; IGI:SGD. | 2 | P28776 | 407 | I23O1_MOUSE Indoleamine 2,3-dioxygenase 1 OS=... | 289 | 2e-42 | 156 | 36 | 54 | GO:0030485; C:smooth muscle contractile fiber; IDA:MGI.::GO:0032421; C:stereocilium bundle; IDA:MGI. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; IDA:MGI. | | | | | | | | | | GO:0007610; P:behavior; IMP:MGI.::GO:0002534; P:cytokine production involved in inflammatory response; IMP:MGI.::GO:0034276; P:kynurenic acid biosynthetic process; IMP:MGI.::GO:0033555; P:multicellular organismal response to stress; IMP:MGI.::GO:0046007; P:negative regulation of activated T cell proliferation; IMP:MGI.::GO:0032693; P:negative regulation of interleukin-10 production; IMP:MGI.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0002678; P:positive regulation of chronic inflammatory response; IMP:MGI.::GO:0032735; P:positive regulation of interleukin-12 production; IMP:MGI.::GO:0002666; P:positive regulation of T cell tolerance induction; IMP:MGI.::GO:0002830; P:positive regulation of type 2 immune response; IMP:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.::GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:MGI. | 3 | Q9ERD9 | 407 | I23O1_RAT Indoleamine 2,3-dioxygenase 1 OS=Ra... | 280 | 7e-41 | 152 | 36 | 54 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0016597; F:amino acid binding; IDA:RGD.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:RGD.::GO:0019825; F:oxygen binding; IDA:RGD. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:RGD. | 4 | Q8R0V5 | 398 | I23O2_MOUSE Indoleamine 2,3-dioxygenase 2 OS=... | 278 | 9e-41 | 152 | 35 | 55 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW. | | | | | | | | | | | 5 | Q6ZQW0 | 407 | I23O2_HUMAN Indoleamine 2,3-dioxygenase 2 OS=... | 286 | 4e-40 | 150 | 35 | 55 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IDA:UniProtKB.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0019441; P:tryptophan catabolic process to kynurenine; IDA:UniProtKB. | 6 | P14902 | 403 | I23O1_HUMAN Indoleamine 2,3-dioxygenase 1 OS=... | 287 | 4e-37 | 142 | 32 | 53 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0033754; F:indoleamine 2,3-dioxygenase activity; IEA:EC.::GO:0004833; F:tryptophan 2,3-dioxygenase activity; EXP:Reactome. | | | | | | | | | | GO:0007565; P:female pregnancy; TAS:ProtInc.::GO:0006569; P:tryptophan catabolic process; TAS:Reactome. | 7 | Q01966 | 378 | MYG_HALDV Myoglobin OS=Haliotis diversicolor ... | 282 | 4e-29 | 119 | 33 | 48 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 8 | P51537 | 378 | MYG_HALMK Myoglobin OS=Haliotis madaka (Giant... | 279 | 8e-29 | 118 | 31 | 46 | | | | | | | | | | | GO:0020037; F:heme binding; IEA:InterPro.::GO:0005344; F:oxygen transporter activity; IEA:UniProtKB-KW. | | | | | | | | | | | 9 | B8FLU0 | 369 | MTNA_DESAA Methylthioribose-1-phosphate isome... | 91 | 1 | 34.7 | 26 | 42 | | | | | | | | | | | GO:0046523; F:S-methyl-5-thioribose-1-phosphate isomerase activity; IEA:EC. | | | | | | | | | | GO:0009086; P:methionine biosynthetic process; IEA:UniProtKB-KW. | 10 | Q47K02 | 281 | Y070_DECAR UPF0042 nucleotide-binding protein... | 73 | 1.5 | 33.9 | 32 | 45 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 11 | B3A0N5 | 554 | APY_TABYA Apyrase OS=Tabanus yao (Horsefly). ... | 65 | 2.2 | 33.9 | 35 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009166; P:nucleotide catabolic process; IEA:InterPro. |