| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q8NF91 | 8797 | SYNE1_HUMAN Nesprin-1 OS=Homo sapiens (Human)... | 130 | 0.056 | 40.4 | 25 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.::GO:0030017; C:sarcomere; IDA:MGI.::GO:0034993; C:SUN-KASH complex; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0005521; F:lamin binding; IPI:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.::GO:0007030; P:Golgi organization; IDA:UniProtKB.::GO:0042692; P:muscle cell differentiation; IDA:UniProtKB.::GO:0090292; P:nuclear matrix anchoring at nuclear membrane; IDA:UniProtKB. | 32 | Q03001 | 7570 | DYST_HUMAN Dystonin OS=Homo sapiens (Human). ... | 227 | 0.61 | 37.4 | 20 | 41 | GO:0015629; C:actin cytoskeleton; IDA:UniProtKB.::GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0033267; C:axon part; IDA:UniProtKB.::GO:0005604; C:basement membrane; TAS:ProtInc.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0031673; C:H zone; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; TAS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.::GO:0045111; C:intermediate filament cytoskeleton; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:UniProtKB.::GO:0035371; C:microtubule plus end; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005178; F:integrin binding; IPI:UniProtKB.::GO:0051010; F:microtubule plus-end binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0048870; P:cell motility; IMP:UniProtKB.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB.::GO:0007229; P:integrin-mediated signaling pathway; NAS:UniProtKB.::GO:0045104; P:intermediate filament cytoskeleton organization; IEP:UniProtKB.::GO:0030011; P:maintenance of cell polarity; IMP:UniProtKB.::GO:0000226; P:microtubule cytoskeleton organization; IDA:UniProtKB.::GO:0009611; P:response to wounding; IDA:UniProtKB. | 33 | Q91ZU6 | 7389 | DYST_MOUSE Dystonin OS=Mus musculus (Mouse). ... | 227 | 0.36 | 38.1 | 20 | 41 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0031673; C:H zone; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0014704; C:intercalated disc; IDA:UniProtKB.::GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:UniProtKB.::GO:0035371; C:microtubule plus end; ISS:UniProtKB.::GO:0060053; C:neurofilament cytoskeleton; IDA:MGI.::GO:0005635; C:nuclear envelope; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:UniProtKB.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; IDA:UniProtKB.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051010; F:microtubule plus-end binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0007409; P:axonogenesis; IMP:MGI.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0031122; P:cytoplasmic microtubule organization; IMP:MGI.::GO:0045104; P:intermediate filament cytoskeleton organization; ISS:UniProtKB.::GO:0046907; P:intracellular transport; IDA:UniProtKB.::GO:0031110; P:regulation of microtubule polymerization or depolymerization; IMP:MGI.::GO:0008090; P:retrograde axon cargo transport; IMP:MGI. | 34 | Q5GN48 | 3674 | DMD_PIG Dystrophin OS=Sus scrofa (Pig). GN=DM... | 282 | 0.0001 | 49.3 | 25 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 35 | Q15149 | 4684 | PLEC_HUMAN Plectin OS=Homo sapiens (Human). G... | 230 | 0.84 | 36.6 | 22 | 41 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0030056; C:hemidesmosome; IDA:UniProtKB.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0042383; C:sarcolemma; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0031581; P:hemidesmosome assembly; IDA:UniProtKB. | 36 | Q6ZWR6 | 8799 | SYNE1_MOUSE Nesprin-1 OS=Mus musculus (Mouse)... | 112 | 0.22 | 38.5 | 28 | 49 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040023; P:establishment of nucleus localization; IMP:MGI. | 37 | Q8C5W0 | 1052 | CLMN_MOUSE Calmin OS=Mus musculus (Mouse). GN... | 122 | 0.00001 | 52 | 32 | 48 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; IDA:MGI.::GO:0031175; P:neuron projection development; IMP:MGI. | 38 | O13728 | 621 | AIN1_SCHPO Alpha-actinin-like protein 1 OS=Sc... | 50 | 0.037 | 40.8 | 42 | 56 | GO:0005826; C:actomyosin contractile ring; IDA:PomBase. | | | | | | | | | | GO:0003779; F:actin binding; TAS:PomBase.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; TAS:PomBase. | | | | | | | | | | GO:0051764; P:actin crosslink formation; TAS:PomBase.::GO:0051017; P:actin filament bundle assembly; TAS:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase. | 39 | P11277 | 2137 | SPTB1_HUMAN Spectrin beta chain, erythrocyte ... | 189 | 0.0002 | 48.5 | 26 | 47 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031235; C:intrinsic to internal side of plasma membrane; TAS:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0008091; C:spectrin; TAS:ProtInc.::GO:0014731; C:spectrin-associated cytoskeleton; IDA:BHF-UCL. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome. | 40 | Q7PKQ5 | 922 | ACTN_ANOGA Alpha-actinin, sarcomeric OS=Anoph... | 94 | 9.2 | 33.1 | 24 | 47 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 41 | P15508 | 2128 | SPTB1_MOUSE Spectrin beta chain, erythrocyte ... | 189 | 0.00004 | 50.8 | 25 | 46 | GO:0008091; C:spectrin; IEA:InterPro. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW. | 42 | P18091 | 924 | ACTN_DROME Alpha-actinin, sarcomeric OS=Droso... | 186 | 0.00003 | 50.8 | 26 | 42 | GO:0030018; C:Z disc; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IPI:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:FlyBase.::GO:0007629; P:flight behavior; IMP:FlyBase.::GO:0045214; P:sarcomere organization; IMP:FlyBase. | 43 | Q9QXS1 | 4691 | PLEC_MOUSE Plectin OS=Mus musculus (Mouse). G... | 230 | 1.3 | 36.2 | 21 | 41 | GO:0043292; C:contractile fiber; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:MGI.::GO:0042383; C:sarcolemma; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB. | 44 | Q96JQ2 | 1002 | CLMN_HUMAN Calmin OS=Homo sapiens (Human). GN... | 102 | 5.2 | 33.9 | 24 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 45 | P30427 | 4687 | PLEC_RAT Plectin OS=Rattus norvegicus (Rat). ... | 230 | 1.2 | 36.2 | 21 | 41 | GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030056; C:hemidesmosome; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; IDA:RGD.::GO:0005200; F:structural constituent of cytoskeleton; IMP:RGD. | | | | | | | | | | GO:0030855; P:epithelial cell differentiation; IEP:RGD.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0031581; P:hemidesmosome assembly; ISS:UniProtKB.::GO:0007584; P:response to nutrient; IDA:RGD. | 46 | Q00963 | 2291 | SPTCB_DROME Spectrin beta chain OS=Drosophila... | 129 | 9.6 | 33.1 | 26 | 45 | GO:0016327; C:apicolateral plasma membrane; TAS:FlyBase.::GO:0030424; C:axon; IDA:FlyBase.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0016328; C:lateral plasma membrane; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0008091; C:spectrin; IEA:InterPro.::GO:0045170; C:spectrosome; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0030506; F:ankyrin binding; IDA:FlyBase.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:FlyBase.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:FlyBase.::GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0016199; P:axon midline choice point recognition; IMP:FlyBase.::GO:0045478; P:fusome organization; TAS:FlyBase.::GO:0042062; P:long-term strengthening of neuromuscular junction; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IDA:FlyBase.::GO:0007026; P:negative regulation of microtubule depolymerization; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IMP:FlyBase.::GO:0072499; P:photoreceptor cell axon guidance; IMP:FlyBase.::GO:0007009; P:plasma membrane organization; TAS:FlyBase.::GO:0030721; P:spectrosome organization; TAS:FlyBase. | 47 | Q6ZWQ0 | 6874 | SYNE2_MOUSE Nesprin-2 OS=Mus musculus (Mouse)... | 116 | 0.69 | 37 | 28 | 43 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IDA:UniProtKB. | | | | | | | | | | GO:0051642; P:centrosome localization; IMP:UniProtKB.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0010761; P:fibroblast migration; IMP:MGI.::GO:0006998; P:nuclear envelope organization; IMP:MGI.::GO:0031022; P:nuclear migration along microfilament; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0034504; P:protein localization to nucleus; IMP:MGI. | 48 | Q08043 | 901 | ACTN3_HUMAN Alpha-actinin-3 OS=Homo sapiens (... | 117 | 0.0002 | 48.1 | 31 | 45 | GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IMP:UniProtKB.::GO:0031143; C:pseudopodium; TAS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005178; F:integrin binding; TAS:UniProtKB.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB. | 49 | Q9JI91 | 894 | ACTN2_MOUSE Alpha-actinin-2 OS=Mus musculus (... | 117 | 0.0002 | 48.1 | 31 | 45 | GO:0005865; C:striated muscle thin filament; TAS:MGI.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; TAS:MGI.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB.::GO:0030375; F:thyroid hormone receptor coactivator activity; IDA:MGI.::GO:0051370; F:ZASP binding; IDA:UniProtKB. | | | | | | | | | | GO:0006936; P:muscle contraction; IPI:MGI. | 50 | Q3ZC55 | 894 | ACTN2_BOVIN Alpha-actinin-2 OS=Bos taurus (Bo... | 117 | 0.0002 | 48.1 | 31 | 45 | GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 51 | P13466 | 857 | GELA_DICDI Gelation factor OS=Dictyostelium d... | 147 | 0.0005 | 47 | 28 | 44 | GO:0030864; C:cortical actin cytoskeleton; IDA:dictyBase.::GO:0005624; C:membrane fraction; IDA:dictyBase.::GO:0001891; C:phagocytic cup; IDA:dictyBase. | | | | | | | | | | GO:0051015; F:actin filament binding; TAS:dictyBase.::GO:0042803; F:protein homodimerization activity; TAS:dictyBase. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:dictyBase.::GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0042331; P:phototaxis; IMP:dictyBase.::GO:0030587; P:sorocarp development; IMP:dictyBase.::GO:0043052; P:thermotaxis; IMP:dictyBase. | 52 | P35609 | 894 | ACTN2_HUMAN Alpha-actinin-2 OS=Homo sapiens (... | 117 | 0.0002 | 48.1 | 31 | 45 | GO:0005884; C:actin filament; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; TAS:UniProtKB.::GO:0005576; C:extracellular region; TAS:Reactome.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IMP:UniProtKB.::GO:0031093; C:platelet alpha granule lumen; TAS:Reactome.::GO:0031143; C:pseudopodium; TAS:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0051373; F:FATZ binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0005178; F:integrin binding; TAS:UniProtKB.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0046983; F:protein dimerization activity; IDA:UniProtKB.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.::GO:0031432; F:titin binding; IDA:BHF-UCL.::GO:0070080; F:titin Z domain binding; IPI:BHF-UCL.::GO:0051370; F:ZASP binding; IDA:UniProtKB. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:UniProtKB.::GO:0030035; P:microspike assembly; IDA:UniProtKB.::GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.::GO:0051289; P:protein homotetramerization; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; NAS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 53 | P20111 | 897 | ACTN2_CHICK Alpha-actinin-2 OS=Gallus gallus ... | 117 | 0.0003 | 48.1 | 31 | 45 | GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0030035; P:microspike assembly; IDA:UniProtKB. | 54 | Q0III9 | 901 | ACTN3_BOVIN Alpha-actinin-3 OS=Bos taurus (Bo... | 117 | 0.0003 | 47.8 | 31 | 45 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 55 | Q9H254 | 2564 | SPTN4_HUMAN Spectrin beta chain, brain 3 OS=H... | 189 | 0.002 | 45.1 | 23 | 44 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0008091; C:spectrin; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; TAS:UniProtKB.::GO:0030506; F:ankyrin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007016; P:cytoskeletal anchoring at plasma membrane; TAS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB. | 56 | O88990 | 900 | ACTN3_MOUSE Alpha-actinin-3 OS=Mus musculus (... | 117 | 0.0003 | 47.8 | 31 | 45 | GO:0005865; C:striated muscle thin filament; TAS:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; TAS:MGI.::GO:0042803; F:protein homodimerization activity; TAS:UniProtKB. | | | | | | | | | | GO:0006936; P:muscle contraction; IPI:MGI. | 57 | Q8WXH0 | 6885 | SYNE2_HUMAN Nesprin-2 OS=Homo sapiens (Human)... | 116 | 2.6 | 35 | 28 | 43 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031527; C:filopodium membrane; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031258; C:lamellipodium membrane; IDA:UniProtKB.::GO:0044429; C:mitochondrial part; IDA:UniProtKB.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0034993; C:SUN-KASH complex; IDA:UniProtKB.::GO:0030018; C:Z disc; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051642; P:centrosome localization; IMP:UniProtKB.::GO:0090286; P:cytoskeletal anchoring at nuclear membrane; IDA:UniProtKB.::GO:0031022; P:nuclear migration along microfilament; ISS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB. | 58 | Q9VDW6 | 3598 | DMDA_DROME Dystrophin, isoforms A/C/F/G/H OS=... | 105 | 0.0009 | 46.6 | 32 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:UniProtKB.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 59 | Q8VHX6 | 2726 | FLNC_MOUSE Filamin-C OS=Mus musculus (Mouse).... | 51 | 9.9 | 33.1 | 35 | 53 | GO:0015629; C:actin cytoskeleton; TAS:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; TAS:MGI. | | | | | | | | | | GO:0030029; P:actin filament-based process; TAS:MGI.::GO:0048747; P:muscle fiber development; IDA:UniProtKB. | 60 | Q9N4M4 | 8545 | ANC1_CAEEL Nuclear anchorage protein 1 OS=Cae... | 107 | 0.002 | 45.4 | 27 | 48 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005640; C:nuclear outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0051179; P:localization; TAS:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase. | 61 | Q14315 | 2725 | FLNC_HUMAN Filamin-C OS=Homo sapiens (Human).... | 51 | 9.8 | 33.1 | 35 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034329; P:cell junction assembly; TAS:Reactome. |
