| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q94125 | 1182 | AGE1_CAEEL Phosphatidylinositol 3-kinase age-... | 530 | 1e-19 | 100 | 24 | 43 | GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:InterPro. | | | | | | | | | | GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007611; P:learning or memory; IMP:WormBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0050920; P:regulation of chemotaxis; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase. | 62 | Q92213 | 1020 | VPS34_CANAX Phosphatidylinositol 3-kinase VPS... | 300 | 3e-18 | 95.5 | 25 | 43 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 63 | P0C5E7 | 1159 | AGE1_CAEBR Phosphatidylinositol 3-kinase age-... | 429 | 2e-17 | 93.2 | 24 | 42 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046934; F:phosphatidylinositol-4,5-bisphosphate 3-kinase activity; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; ISS:UniProtKB.::GO:0040024; P:dauer larval development; ISS:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 64 | Q6CAD2 | 2282 | ATM_YARLI Serine/threonine-protein kinase TEL... | 223 | 0.00000000006 | 72 | 28 | 42 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 65 | Q9VK45 | 2470 | TOR_DROME Target of rapamycin OS=Drosophila m... | 73 | 0.0000000002 | 70.1 | 44 | 67 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; NAS:FlyBase.::GO:0043621; F:protein self-association; IDA:FlyBase. | | | | | | | | | | GO:0006914; P:autophagy; IMP:FlyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0009594; P:detection of nutrient; TAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0032456; P:endocytic recycling; IDA:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0035264; P:multicellular organism growth; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; NAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; TAS:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0090070; P:positive regulation of ribosome biogenesis; IMP:FlyBase.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IGI:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. | 66 | Q86C65 | 2380 | TOR_DICDI Target of rapamycin OS=Dictyosteliu... | 96 | 0.0000000004 | 69.3 | 38 | 58 | GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 67 | Q5UR69 | 701 | YL615_MIMIV Putative phosphatidylinositol kin... | 245 | 0.0000000007 | 67.8 | 25 | 47 | | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 68 | Q8N8J0 | 262 | PI4P1_HUMAN Putative phosphatidylinositol 4-k... | 169 | 0.007 | 44.3 | 26 | 43 | | | | | | | | | | | | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 69 | Q0DJS1 | 2465 | TOR_ORYSJ Serine/threonine-protein kinase TOR... | 84 | 0.000000002 | 67.4 | 39 | 61 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 70 | Q02099 | 2386 | RAD3_SCHPO Protein kinase rad3 OS=Schizosacch... | 174 | 0.000000002 | 67 | 26 | 46 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0000228; C:nuclear chromosome; IDA:PomBase.::GO:0043234; C:protein complex; NAS:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0031573; P:intra-S DNA damage checkpoint; IDA:PomBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; NAS:PomBase. | 71 | O14356 | 2335 | TOR1_SCHPO Phosphatidylinositol 3-kinase tor1... | 105 | 0.000000002 | 67 | 35 | 58 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007569; P:cell aging; TAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0031142; P:induction of conjugation upon nitrogen starvation; IMP:PomBase.::GO:0043091; P:L-arginine import; IMP:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; NAS:PomBase.::GO:0060357; P:regulation of leucine import; IMP:PomBase.::GO:0009266; P:response to temperature stimulus; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 72 | Q9FR53 | 2481 | TOR_ARATH Serine/threonine-protein kinase TOR... | 214 | 0.000000003 | 66.6 | 25 | 42 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0043621; F:protein self-association; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000975; F:regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IGI:UniProtKB.::GO:0040019; P:positive regulation of embryonic development; IMP:UniProtKB.::GO:2000234; P:positive regulation of rRNA processing; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0009303; P:rRNA transcription; IMP:TAIR. | 73 | P42346 | 2549 | MTOR_RAT Serine/threonine-protein kinase mTOR... | 71 | 0.000000003 | 66.2 | 44 | 65 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0070438; C:mTOR-FKBP12-rapamycin complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031931; C:TORC1 complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:RGD.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:RGD.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IMP:RGD.::GO:0043610; P:regulation of carbohydrate utilization; IDA:RGD.::GO:0031998; P:regulation of fatty acid beta-oxidation; IDA:RGD.::GO:0005979; P:regulation of glycogen biosynthetic process; IDA:RGD.::GO:0032095; P:regulation of response to food; IDA:RGD. | 74 | Q9JLN9 | 2549 | MTOR_MOUSE Serine/threonine-protein kinase mT... | 71 | 0.000000003 | 66.2 | 44 | 65 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; IDA:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0045792; P:negative regulation of cell size; IGI:MGI.::GO:0016242; P:negative regulation of macroautophagy; IMP:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.::GO:0043200; P:response to amino acid stimulus; IDA:MGI.::GO:0032868; P:response to insulin stimulus; IDA:MGI.::GO:0031529; P:ruffle organization; IDA:MGI. | 75 | P42345 | 2549 | MTOR_HUMAN Serine/threonine-protein kinase mT... | 71 | 0.000000004 | 65.9 | 44 | 65 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0031931; C:TORC1 complex; IDA:UniProtKB.::GO:0031932; C:TORC2 complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.::GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.::GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.::GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; TAS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:UniProtKB.::GO:0007584; P:response to nutrient; NAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB. | 76 | Q95Q95 | 2697 | TOR_CAEEL Target of rapamycin homolog OS=Caen... | 71 | 0.000000005 | 65.9 | 42 | 65 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0000492; P:box C/D snoRNP assembly; IMP:WormBase.::GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006629; P:lipid metabolic process; IMP:WormBase.::GO:0045727; P:positive regulation of translation; IMP:WormBase.::GO:0009408; P:response to heat; IMP:WormBase.::GO:0031929; P:TOR signaling cascade; IMP:WormBase.::GO:0006412; P:translation; IMP:WormBase. | 77 | Q9Y7K2 | 2337 | TOR2_SCHPO Phosphatidylinositol 3-kinase tor2... | 81 | 0.00000001 | 64.3 | 38 | 62 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0034064; C:Tor2-Mei2-Ste11 complex; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:PomBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0030996; P:cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0031670; P:cellular response to nutrient; NAS:PomBase.::GO:0010507; P:negative regulation of autophagy; IMP:PomBase.::GO:0010503; P:negative regulation of cell cycle arrest in response to nitrogen starvation; IMP:PomBase.::GO:0010515; P:negative regulation of induction of conjugation with cellular fusion; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 78 | Q75DB8 | 2324 | ATR_ASHGO Serine/threonine-protein kinase MEC... | 109 | 0.00000003 | 62.8 | 32 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 79 | P0CP61 | 2968 | ATM_CRYNB Serine/threonine-protein kinase TEL... | 109 | 0.00000005 | 62.4 | 30 | 54 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 80 | P0CP60 | 2967 | ATM_CRYNJ Serine/threonine-protein kinase TEL... | 109 | 0.00000005 | 62.4 | 30 | 54 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008565; F:protein transporter activity; IEA:InterPro. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro. | 81 | Q70PP2 | 3218 | SMG1_DROME Serine/threonine-protein kinase Sm... | 136 | 0.00000007 | 62 | 27 | 49 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IMP:UniProtKB.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0050808; P:synapse organization; IDA:FlyBase.::GO:0048489; P:synaptic vesicle transport; IDA:FlyBase. | 82 | P32600 | 2474 | TOR2_YEAST Serine/threonine-protein kinase TO... | 215 | 0.00000008 | 61.6 | 25 | 40 | GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD. | | | | | | | | | | GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD. | | | | | | | | | | GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:SGD.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:SGD.::GO:0010507; P:negative regulation of autophagy; IGI:SGD.::GO:0045807; P:positive regulation of endocytosis; IMP:SGD.::GO:0051726; P:regulation of cell cycle; TAS:SGD.::GO:0001558; P:regulation of cell growth; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; IMP:SGD.::GO:0042254; P:ribosome biogenesis; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD. | 83 | O01510 | 2322 | SMG1_CAEEL Serine/threonine-protein kinase sm... | 118 | 0.0000001 | 60.8 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0030539; P:male genitalia development; IMP:WormBase.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IGI:WormBase. | 84 | Q5BHE2 | 2793 | ATM_EMENI Serine/threonine-protein kinase tel... | 223 | 0.0000002 | 60.1 | 24 | 41 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 85 | P35169 | 2470 | TOR1_YEAST Serine/threonine-protein kinase TO... | 239 | 0.0000002 | 60.1 | 24 | 39 | GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0010507; P:negative regulation of autophagy; IGI:SGD.::GO:0051726; P:regulation of cell cycle; IMP:SGD.::GO:0001558; P:regulation of cell growth; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.::GO:0042254; P:ribosome biogenesis; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:SGD. | 86 | P38110 | 2787 | ATM_YEAST Serine/threonine-protein kinase TEL... | 270 | 0.0000002 | 60.1 | 23 | 40 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0042162; F:telomeric DNA binding; IDA:SGD. | | | | | | | | | | GO:0006975; P:DNA damage induced protein phosphorylation; IMP:SGD.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0016572; P:histone phosphorylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 87 | P38111 | 2368 | ATR_YEAST Serine/threonine-protein kinase MEC... | 239 | 0.0000005 | 58.9 | 22 | 40 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; TAS:SGD.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:SGD.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IMP:SGD.::GO:0016572; P:histone phosphorylation; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0000722; P:telomere maintenance via recombination; IGI:SGD. | 88 | Q61CW2 | 2313 | SMG1_CAEBR Serine/threonine-protein kinase sm... | 118 | 0.0000008 | 58.5 | 29 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW. | 89 | Q22258 | 2531 | ATR_CAEEL Serine/threonine-protein kinase ATR... | 99 | 0.0000008 | 58.5 | 31 | 46 | GO:0000794; C:condensed nuclear chromosome; TAS:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase. | 90 | Q2U639 | 2925 | ATM_ASPOR Serine/threonine-protein kinase tel... | 107 | 0.000002 | 57 | 30 | 50 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 91 | Q4WVM7 | 2796 | ATM_ASPFU Serine/threonine-protein kinase tel... | 107 | 0.000004 | 56.2 | 30 | 51 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. |
