rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | Q17941 | 541 | AKT1_CAEEL Serine/threonine-protein kinase ak... | 54 | 0.000001 | 56.2 | 48 | 69 | GO:0005622; C:intracellular; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IDA:WormBase.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:WormBase. | | | | | | | | | | GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; IMP:WormBase. | 242 | Q98TY9 | 481 | AKT1_XENLA RAC-alpha serine/threonine-protein... | 46 | 0.00001 | 52.4 | 41 | 63 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 243 | P93025 | 915 | PHOT2_ARATH Phototropin-2 OS=Arabidopsis thal... | 97 | 0.0000000000005 | 77 | 41 | 61 | GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IMP:TAIR.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009902; P:chloroplast relocation; TAS:TAIR.::GO:0010362; P:negative regulation of anion channel activity by blue light; IMP:TAIR.::GO:0009638; P:phototropism; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; TAS:TAIR.::GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0010118; P:stomatal movement; IMP:TAIR. | 244 | P49673 | 337 | KAPC_ASCSU cAMP-dependent protein kinase cata... | 68 | 0.000001 | 55.1 | 37 | 59 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 245 | Q19266 | 597 | KPC3_CAEEL Protein kinase C-like 3 OS=Caenorh... | 43 | 0.000006 | 53.9 | 42 | 72 | GO:0016324; C:apical plasma membrane; IDA:WormBase.::GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB.::GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007163; P:establishment or maintenance of cell polarity; IGI:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW. | 246 | A8WUG4 | 597 | KPC3_CAEBR Protein kinase C-like 3 OS=Caenorh... | 108 | 0.000005 | 53.9 | 29 | 52 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007163; P:establishment or maintenance of cell polarity; ISS:UniProtKB.::GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007506; P:gonadal mesoderm development; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007338; P:single fertilization; IEA:UniProtKB-KW. | 247 | Q9Z2A0 | 559 | PDPK1_MOUSE 3-phosphoinositide-dependent prot... | 44 | 0.033 | 41.6 | 39 | 64 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006972; P:hyperosmotic response; IDA:MGI.::GO:0010667; P:negative regulation of cardiac muscle cell apoptotic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0010594; P:regulation of endothelial cell migration; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0003323; P:type B pancreatic cell development; IMP:UniProtKB. | 248 | Q753D9 | 726 | PKH3_ASHGO Serine/threonine-protein kinase PK... | 70 | 0.0005 | 47.8 | 34 | 57 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 249 | O55173 | 559 | PDPK1_RAT 3-phosphoinositide-dependent protei... | 44 | 0.033 | 41.6 | 39 | 64 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:RGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0019901; F:protein kinase binding; IDA:RGD. | | | | | | | | | | GO:0048041; P:focal adhesion assembly; IMP:RGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 250 | P24723 | 683 | KPCL_HUMAN Protein kinase C eta type OS=Homo ... | 54 | 0.000003 | 54.7 | 46 | 63 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; IMP:UniProtKB. | 251 | O15530 | 556 | PDPK1_HUMAN 3-phosphoinositide-dependent prot... | 44 | 0.041 | 41.2 | 39 | 64 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0032148; P:activation of protein kinase B activity; IDA:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0006469; P:negative regulation of protein kinase activity; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046777; P:protein autophosphorylation; TAS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 252 | P16911 | 376 | KDC1_DROME Protein kinase DC1 OS=Drosophila m... | 44 | 0.00003 | 50.8 | 39 | 70 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase. | | | | | | | | | | | 253 | O77676 | 671 | KGP1_RABIT cGMP-dependent protein kinase 1 OS... | 145 | 0.0000003 | 58.2 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB. | 254 | Q13976 | 671 | KGP1_HUMAN cGMP-dependent protein kinase 1 OS... | 107 | 0.0000004 | 57.8 | 32 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; IDA:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0090331; P:negative regulation of platelet aggregation; IMP:UniProtKB.::GO:0043087; P:regulation of GTPase activity; IMP:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc. | 255 | P00516 | 671 | KGP1_BOVIN cGMP-dependent protein kinase 1 OS... | 107 | 0.0000004 | 57.8 | 32 | 52 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB. | 256 | P0C605 | 671 | KGP1_MOUSE cGMP-dependent protein kinase 1 OS... | 107 | 0.0000004 | 57.8 | 32 | 52 | GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IMP:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; ISS:UniProtKB.::GO:0030553; F:cGMP binding; IDA:UniProtKB.::GO:0004692; F:cGMP-dependent protein kinase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0016358; P:dendrite development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0043087; P:regulation of GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:UniProtKB. | 257 | Q6A1A2 | 396 | PDPK2_HUMAN Putative 3-phosphoinositide-depen... | 91 | 0.038 | 41.2 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 258 | P05126 | 671 | KPCB_BOVIN Protein kinase C beta type OS=Bos ... | 81 | 0.0000004 | 57.8 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 259 | P10102 | 672 | KPCA_RABIT Protein kinase C alpha type OS=Ory... | 62 | 0.000003 | 55.1 | 39 | 60 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB. | 260 | P05772 | 671 | KPCB_RABIT Protein kinase C beta type OS=Oryc... | 81 | 0.0000004 | 57.8 | 36 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 261 | P68403 | 671 | KPCB_RAT Protein kinase C beta type OS=Rattus... | 81 | 0.0000004 | 57.8 | 36 | 52 | GO:0031526; C:brush border membrane; IDA:RGD.::GO:0005813; C:centrosome; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0042488; P:positive regulation of odontogenesis of dentin-containing tooth; IEP:RGD.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0014059; P:regulation of dopamine secretion; IMP:RGD.::GO:0040008; P:regulation of growth; IMP:RGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0042493; P:response to drug; IMP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0033280; P:response to vitamin D; IEP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 262 | P68404 | 671 | KPCB_MOUSE Protein kinase C beta type OS=Mus ... | 81 | 0.0000004 | 57.8 | 36 | 52 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005246; F:calcium channel regulator activity; IDA:MGI.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); ISS:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0006816; P:calcium ion transport; IDA:MGI.::GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0010829; P:negative regulation of glucose transport; IMP:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 263 | P05771 | 671 | KPCB_HUMAN Protein kinase C beta type OS=Homo... | 81 | 0.0000004 | 57.8 | 36 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0050681; F:androgen receptor binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.::GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0005080; F:protein kinase C binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042113; P:B cell activation; ISS:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0042953; P:lipoprotein transport; TAS:BHF-UCL.::GO:0010829; P:negative regulation of glucose transport; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0030949; P:positive regulation of vascular endothelial growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 264 | O48963 | 996 | PHOT1_ARATH Phototropin-1 OS=Arabidopsis thal... | 92 | 0.00000000003 | 71.2 | 37 | 59 | GO:0009986; C:cell surface; IDA:TAIR.::GO:0009898; C:internal side of plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009882; F:blue light photoreceptor activity; IDA:TAIR.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0000155; F:two-component sensor activity; IEA:InterPro. | | | | | | | | | | GO:0009904; P:chloroplast accumulation movement; IMP:TAIR.::GO:0009903; P:chloroplast avoidance movement; IMP:TAIR.::GO:0010362; P:negative regulation of anion channel activity by blue light; IMP:TAIR.::GO:0009638; P:phototropism; IMP:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0018298; P:protein-chromophore linkage; IEA:UniProtKB-KW.::GO:0010155; P:regulation of proton transport; IGI:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. | 265 | P17252 | 672 | KPCA_HUMAN Protein kinase C alpha type OS=Hom... | 62 | 0.000002 | 55.1 | 39 | 60 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:BHF-UCL.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:BHF-UCL.::GO:0035403; F:histone kinase activity (H3-T6 specific); IDA:UniProtKB.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0045766; P:positive regulation of angiogenesis; IMP:UniProtKB.::GO:0043536; P:positive regulation of blood vessel endothelial cell migration; IDA:DFLAT.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; IMP:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0090330; P:regulation of platelet aggregation; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 266 | P04409 | 672 | KPCA_BOVIN Protein kinase C alpha type OS=Bos... | 62 | 0.000002 | 55.1 | 39 | 60 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0010595; P:positive regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB. | 267 | P05696 | 672 | KPCA_RAT Protein kinase C alpha type OS=Rattu... | 62 | 0.000003 | 55.1 | 39 | 60 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0021955; P:central nervous system neuron axonogenesis; IMP:RGD.::GO:0045184; P:establishment of protein localization; TAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0007611; P:learning or memory; IMP:RGD.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0045822; P:negative regulation of heart contraction; IMP:RGD.::GO:0017148; P:negative regulation of translation; IMP:RGD.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:RGD.::GO:0045766; P:positive regulation of angiogenesis; ISS:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IDA:UniProtKB.::GO:0045785; P:positive regulation of cell adhesion; ISS:UniProtKB.::GO:2000707; P:positive regulation of dense core granule biogenesis; ISS:UniProtKB.::GO:0001938; P:positive regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:RGD.::GO:0031666; P:positive regulation of lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0045651; P:positive regulation of macrophage differentiation; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0051965; P:positive regulation of synapse assembly; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0048259; P:regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0046677; P:response to antibiotic; IEP:RGD.::GO:0051412; P:response to corticosterone stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IMP:RGD.::GO:0045471; P:response to ethanol; IMP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; IMP:RGD.::GO:0009636; P:response to toxin; IEP:RGD. | 268 | Q64617 | 683 | KPCL_RAT Protein kinase C eta type OS=Rattus ... | 54 | 0.000003 | 54.7 | 46 | 63 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; ISS:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070528; P:protein kinase C signaling cascade; IMP:RGD.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB. | 269 | P24583 | 1151 | KPC1_YEAST Protein kinase C-like 1 OS=Sacchar... | 53 | 0.0000007 | 57.4 | 42 | 66 | GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005856; C:cytoskeleton; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.::GO:0030427; C:site of polarized growth; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:SGD. | | | | | | | | | | GO:0007015; P:actin filament organization; IGI:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0007243; P:intracellular protein kinase cascade; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:SGD. | 270 | P23298 | 683 | KPCL_MOUSE Protein kinase C eta type OS=Mus m... | 54 | 0.000003 | 54.7 | 46 | 63 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0050861; P:positive regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:UniProtKB.::GO:0010744; P:positive regulation of macrophage derived foam cell differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:2000810; P:regulation of tight junction assembly; ISS:UniProtKB. | 271 | P43057 | 1097 | KPC1_CANAX Protein kinase C-like 1 OS=Candida... | 58 | 0.000001 | 56.6 | 38 | 59 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. |