| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
901 | P16879 | 822 | FES_MOUSE Tyrosine-protein kinase Fes/Fps OS=... | 260 | 4e-24 | 112 | 31 | 46 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031234; C:extrinsic to internal side of plasma membrane; ISS:UniProtKB.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034987; F:immunoglobulin receptor binding; ISS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0035091; F:phosphatidylinositol binding; ISS:UniProtKB. | | | | | | | | | | GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:UniProtKB.::GO:2000251; P:positive regulation of actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031116; P:positive regulation of microtubule polymerization; ISS:UniProtKB.::GO:0045639; P:positive regulation of myeloid cell differentiation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:2000145; P:regulation of cell motility; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB. | 902 | Q7YRC6 | 344 | AURKB_BOVIN Aurora kinase B OS=Bos taurus (Bo... | 268 | 4e-24 | 109 | 25 | 49 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 903 | Q86AD7 | 392 | MYLKB_DICDI Probable myosin light chain kinas... | 275 | 4e-24 | 109 | 28 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0007165; P:signal transduction; ISS:dictyBase. | 904 | Q9LYQ8 | 456 | CIPK2_ARATH CBL-interacting serine/threonine-... | 269 | 4e-24 | 110 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 905 | Q9H4A3 | 2382 | WNK1_HUMAN Serine/threonine-protein kinase WN... | 320 | 4e-24 | 113 | 28 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0019902; F:phosphatase binding; IDA:UniProtKB.::GO:0004860; F:protein kinase inhibitor activity; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006811; P:ion transport; ISS:UniProtKB.::GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0048666; P:neuron development; NAS:UniProtKB. | 906 | Q9QYZ4 | 484 | SMOK1_MOUSE Sperm motility kinase 1 OS=Mus mu... | 268 | 4e-24 | 110 | 29 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 907 | Q16539 | 360 | MK14_HUMAN Mitogen-activated protein kinase 1... | 262 | 4e-24 | 109 | 28 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0051525; F:NFAT protein binding; ISS:BHF-UCL. | | | | | | | | | | GO:0070935; P:3'-UTR-mediated mRNA stabilization; TAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006928; P:cellular component movement; TAS:ProtInc.::GO:0071363; P:cellular response to growth factor stimulus; IMP:BHF-UCL.::GO:0071479; P:cellular response to ionizing radiation; IMP:BHF-UCL.::GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0042692; P:muscle cell differentiation; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030316; P:osteoclast differentiation; ISS:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051149; P:positive regulation of muscle cell differentiation; TAS:Reactome.::GO:2000379; P:positive regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; TAS:Reactome.::GO:0042770; P:signal transduction in response to DNA damage; IMP:BHF-UCL.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0090400; P:stress-induced premature senescence; IMP:BHF-UCL.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IMP:BHF-UCL. | 908 | Q04859 | 622 | MAK_MOUSE Serine/threonine-protein kinase MAK... | 298 | 4e-24 | 112 | 25 | 46 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0072686; C:mitotic spindle; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0001917; C:photoreceptor inner segment; ISS:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB. | | | | | | | | | | GO:0045494; P:photoreceptor cell maintenance; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 909 | Q7XKA8 | 370 | SAPK5_ORYSJ Serine/threonine-protein kinase S... | 273 | 4e-24 | 109 | 32 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW. | 910 | Q8N568 | 766 | DCLK2_HUMAN Serine/threonine-protein kinase D... | 281 | 4e-24 | 112 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 911 | Q9H093 | 628 | NUAK2_HUMAN NUAK family SNF1-like kinase 2 OS... | 236 | 4e-24 | 112 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB. | 912 | O43293 | 454 | DAPK3_HUMAN Death-associated protein kinase 3... | 230 | 4e-24 | 110 | 30 | 51 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0043522; F:leucine zipper domain binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; TAS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:2000249; P:regulation of actin cytoskeleton reorganization; TAS:UniProtKB.::GO:0010506; P:regulation of autophagy; TAS:UniProtKB.::GO:2000145; P:regulation of cell motility; TAS:UniProtKB.::GO:0007088; P:regulation of mitosis; TAS:UniProtKB.::GO:0006940; P:regulation of smooth muscle contraction; TAS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 913 | P35567 | 302 | CDK1A_XENLA Cyclin-dependent kinase 1-A OS=Xe... | 239 | 4e-24 | 108 | 28 | 53 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 914 | Q2QYM3 | 439 | CIPKE_ORYSJ CBL-interacting protein kinase 14... | 229 | 4e-24 | 109 | 29 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 915 | P11802 | 303 | CDK4_HUMAN Cyclin-dependent kinase 4 OS=Homo ... | 262 | 4e-24 | 108 | 29 | 49 | GO:0000785; C:chromatin; IDA:UniProtKB.::GO:0000307; C:cyclin-dependent protein kinase holoenzyme complex; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:BHF-UCL.::GO:0048146; P:positive regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0010468; P:regulation of gene expression; IMP:BHF-UCL.::GO:0042493; P:response to drug; IGI:UniProtKB.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome. | 916 | O88445 | 282 | AURKC_MOUSE Aurora kinase C OS=Mus musculus (... | 268 | 4e-24 | 108 | 25 | 47 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000793; C:condensed chromosome; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 917 | P49840 | 483 | GSK3A_HUMAN Glycogen synthase kinase-3 alpha ... | 241 | 4e-24 | 110 | 34 | 51 | GO:0030877; C:beta-catenin destruction complex; TAS:UniProtKB.::GO:0005829; C:cytosol; TAS:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0050321; F:tau-protein kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0003214; P:cardiac left ventricle morphogenesis; ISS:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; TAS:UniProtKB.::GO:0061052; P:negative regulation of cell growth involved in cardiac muscle cell development; ISS:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IMP:BHF-UCL.::GO:2000466; P:negative regulation of glycogen (starch) synthase activity; TAS:UniProtKB.::GO:0045719; P:negative regulation of glycogen biosynthetic process; TAS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0032007; P:negative regulation of TOR signaling cascade; ISS:BHF-UCL.::GO:2000077; P:negative regulation of type B pancreatic cell development; TAS:UniProtKB.::GO:0010905; P:negative regulation of UDP-glucose catabolic process; IC:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0071879; P:positive regulation of adrenergic receptor signaling pathway; ISS:BHF-UCL.::GO:0030819; P:positive regulation of cAMP biosynthetic process; ISS:BHF-UCL.::GO:2000467; P:positive regulation of glycogen (starch) synthase activity; ISS:BHF-UCL.::GO:0045823; P:positive regulation of heart contraction; ISS:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; NAS:BHF-UCL.::GO:0003073; P:regulation of systemic arterial blood pressure; ISS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 918 | Q9XIW0 | 429 | CIPK7_ARATH CBL-interacting serine/threonine-... | 274 | 4e-24 | 109 | 31 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009409; P:response to cold; IEP:TAIR.::GO:0007165; P:signal transduction; IEA:InterPro. | 919 | Q90336 | 361 | MK14A_CYPCA Mitogen-activated protein kinase ... | 306 | 4e-24 | 109 | 27 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 920 | B7XHR6 | 595 | KIN1_ENTBH Probable serine/threonine-protein ... | 212 | 4e-24 | 111 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006887; P:exocytosis; IEA:UniProtKB-KW. | 921 | P09216 | 737 | KPCE_RAT Protein kinase C epsilon type OS=Rat... | 210 | 4e-24 | 112 | 33 | 52 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; ISS:UniProtKB. | 922 | P52304 | 576 | POLO_DROME Serine/threonine-protein kinase po... | 266 | 4e-24 | 111 | 26 | 48 | GO:0005813; C:centrosome; IDA:FlyBase.::GO:0000940; C:condensed chromosome outer kinetochore; IDA:FlyBase.::GO:0005874; C:microtubule; IDA:FlyBase.::GO:0030496; C:midbody; IDA:FlyBase.::GO:0005635; C:nuclear envelope; IDA:FlyBase.::GO:0000922; C:spindle pole; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; TAS:FlyBase.::GO:0007060; P:male meiosis chromosome segregation; TAS:FlyBase.::GO:0007067; P:mitosis; IMP:FlyBase.::GO:0007052; P:mitotic spindle organization; IMP:FlyBase.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0007344; P:pronuclear fusion; IMP:FlyBase.::GO:0035046; P:pronuclear migration; IMP:FlyBase.::GO:0008104; P:protein localization; NAS:FlyBase.::GO:0035044; P:sperm aster formation; IMP:FlyBase.::GO:0007058; P:spindle assembly involved in female meiosis II; IMP:FlyBase. | 923 | O02812 | 360 | MK14_CANFA Mitogen-activated protein kinase 1... | 262 | 5e-24 | 108 | 28 | 50 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 924 | P50526 | 652 | SSP1_SCHPO Serine/threonine-protein kinase ss... | 275 | 5e-24 | 112 | 30 | 48 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0030428; C:cell septum; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030042; P:actin filament depolymerization; IGI:PomBase.::GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0033554; P:cellular response to stress; IMP:PomBase.::GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:PomBase.::GO:0070317; P:negative regulation of G0 to G1 transition; IMP:PomBase.::GO:0007165; P:signal transduction; IC:PomBase. | 925 | Q09147 | 1052 | FGFR2_DROME Fibroblast growth factor receptor... | 297 | 5e-24 | 112 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IC:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005007; F:fibroblast growth factor-activated receptor activity; ISS:FlyBase. | | | | | | | | | | GO:0000187; P:activation of MAPK activity; IEP:FlyBase.::GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0035153; P:epithelial cell type specification, open tracheal system; IMP:FlyBase.::GO:0046847; P:filopodium assembly; IMP:FlyBase.::GO:0035215; P:genital disc development; IEP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0030517; P:negative regulation of axon extension; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0007435; P:salivary gland morphogenesis; NAS:FlyBase.::GO:0007429; P:secondary branching, open tracheal system; IMP:FlyBase.::GO:0007430; P:terminal branching, open tracheal system; IMP:FlyBase.::GO:0007426; P:tracheal outgrowth, open tracheal system; IMP:FlyBase. | 926 | P23458 | 1154 | JAK1_HUMAN Tyrosine-protein kinase JAK1 OS=Ho... | 287 | 0.0000001 | 59.7 | 24 | 43 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005131; F:growth hormone receptor binding; ISS:BHF-UCL.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0046677; P:response to antibiotic; IDA:MGI.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome. | 927 | O70126 | 345 | AURKB_MOUSE Aurora kinase B OS=Mus musculus (... | 212 | 5e-24 | 108 | 29 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 928 | Q6BS08 | 875 | ATG1_DEBHA Serine/threonine-protein kinase AT... | 312 | 5e-24 | 112 | 25 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 929 | Q5R7G9 | 628 | NUAK2_PONAB NUAK family SNF1-like kinase 2 OS... | 236 | 5e-24 | 111 | 30 | 49 | | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB. | 930 | P34331 | 649 | PLK1_CAEEL Serine/threonine-protein kinase pl... | 273 | 5e-24 | 111 | 26 | 48 | GO:0005813; C:centrosome; IDA:WormBase.::GO:0000793; C:condensed chromosome; IDA:WormBase.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0007417; P:central nervous system development; IMP:UniProtKB.::GO:0007098; P:centrosome cycle; IMP:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0045132; P:meiotic chromosome segregation; IMP:WormBase.::GO:0007067; P:mitosis; IMP:WormBase.::GO:0007077; P:mitotic nuclear envelope disassembly; IMP:UniProtKB.::GO:0007052; P:mitotic spindle organization; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048477; P:oogenesis; IMP:WormBase.::GO:0040038; P:polar body extrusion after meiotic divisions; IMP:WormBase.::GO:0051726; P:regulation of cell cycle; IMP:WormBase. | 931 | A8XA58 | 326 | CDK1_CAEBR Cyclin-dependent kinase 1 OS=Caeno... | 241 | 5e-24 | 108 | 29 | 51 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051446; P:positive regulation of meiotic cell cycle; ISS:UniProtKB. |
