| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | O08696 | 760 | FOXM1_MOUSE Forkhead box protein M1 OS=Mus mu... | 155 | 0.0000000000004 | 76.6 | 34 | 46 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:2000781; P:positive regulation of double-strand break repair; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 182 | Q66J77 | 430 | FOXN2_XENLA Forkhead box protein N2 OS=Xenopu... | 93 | 0.0000000000005 | 75.5 | 41 | 62 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 183 | Q498D1 | 711 | FOXP1_RAT Forkhead box protein P1 OS=Rattus n... | 83 | 0.0000000000005 | 76.3 | 40 | 65 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; IBA:RefGenome.::GO:0033152; P:immunoglobulin V(D)J recombination; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002639; P:positive regulation of immunoglobulin production; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0002329; P:pre-B cell differentiation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome. | 184 | P58462 | 705 | FOXP1_MOUSE Forkhead box protein P1 OS=Mus mu... | 83 | 0.0000000000005 | 75.9 | 40 | 65 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:MGI.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0042803; F:protein homodimerization activity; IPI:MGI.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; IMP:MGI.::GO:0033152; P:immunoglobulin V(D)J recombination; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:2000727; P:positive regulation of cardiac muscle cell differentiation; IMP:MGI.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002639; P:positive regulation of immunoglobulin production; IMP:MGI.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0002329; P:pre-B cell differentiation; IMP:MGI.::GO:0060043; P:regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0045214; P:sarcomere organization; IGI:MGI.::GO:0007519; P:skeletal muscle tissue development; IGI:MGI.::GO:0048745; P:smooth muscle tissue development; IGI:MGI.::GO:0021517; P:ventral spinal cord development; IEP:UniProtKB. | 185 | A4IFD2 | 674 | FOXP1_BOVIN Forkhead box protein P1 OS=Bos ta... | 83 | 0.0000000000005 | 75.9 | 40 | 65 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; IBA:RefGenome.::GO:0033152; P:immunoglobulin V(D)J recombination; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002639; P:positive regulation of immunoglobulin production; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0002329; P:pre-B cell differentiation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome. | 186 | Q9H334 | 677 | FOXP1_HUMAN Forkhead box protein P1 OS=Homo s... | 83 | 0.0000000000006 | 75.9 | 40 | 65 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; IBA:RefGenome.::GO:0033152; P:immunoglobulin V(D)J recombination; IBA:RefGenome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002639; P:positive regulation of immunoglobulin production; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0002329; P:pre-B cell differentiation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome. | 187 | Q58NQ4 | 686 | FOXP1_CHICK Forkhead box protein P1 OS=Gallus... | 83 | 0.0000000000007 | 75.5 | 40 | 65 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003682; F:chromatin binding; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0046982; F:protein heterodimerization activity; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055007; P:cardiac muscle cell differentiation; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0033152; P:immunoglobulin V(D)J recombination; IBA:RefGenome.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0060501; P:positive regulation of epithelial cell proliferation involved in lung morphogenesis; IBA:RefGenome.::GO:0002639; P:positive regulation of immunoglobulin production; IBA:RefGenome.::GO:0002053; P:positive regulation of mesenchymal cell proliferation; IBA:RefGenome.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002329; P:pre-B cell differentiation; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0007519; P:skeletal muscle tissue development; IBA:RefGenome.::GO:0048745; P:smooth muscle tissue development; IBA:RefGenome.::GO:0021517; P:ventral spinal cord development; IEP:UniProtKB. | 188 | Q4VYS1 | 706 | FOXP2_XENLA Forkhead box protein P2 OS=Xenopu... | 83 | 0.0000000000007 | 75.5 | 41 | 65 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021757; P:caudate nucleus development; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0021758; P:putamen development; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 189 | Q2LE08 | 659 | FXP1B_DANRE Forkhead box protein P1-B OS=Dani... | 82 | 0.000000000001 | 75.1 | 40 | 65 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 190 | Q5W1J5 | 578 | FOXP1_XENLA Forkhead box protein P1 OS=Xenopu... | 91 | 0.000000000001 | 74.7 | 38 | 62 | GO:0005634; C:nucleus; NAS:UniProtKB. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 191 | O15353 | 648 | FOXN1_HUMAN Forkhead box protein N1 OS=Homo s... | 96 | 0.000000000001 | 74.7 | 40 | 56 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006952; P:defense response; TAS:ProtInc.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0050673; P:epithelial cell proliferation; IBA:RefGenome.::GO:0030216; P:keratinocyte differentiation; IBA:RefGenome.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0048538; P:thymus development; IBA:RefGenome. | 192 | Q61575 | 648 | FOXN1_MOUSE Forkhead box protein N1 OS=Mus mu... | 96 | 0.000000000002 | 74.3 | 40 | 56 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IBA:RefGenome.::GO:0050673; P:epithelial cell proliferation; IDA:UniProtKB.::GO:0030216; P:keratinocyte differentiation; IDA:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0033081; P:regulation of T cell differentiation in thymus; IMP:MGI.::GO:0048538; P:thymus development; IMP:MGI. | 193 | P97691 | 759 | FOXM1_RAT Forkhead box protein M1 OS=Rattus n... | 155 | 0.000000000002 | 74.3 | 33 | 46 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:RGD.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000086; P:G2/M transition of mitotic cell cycle; ISS:UniProtKB.::GO:0001889; P:liver development; IBA:RefGenome.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0008284; P:positive regulation of cell proliferation; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0071156; P:regulation of cell cycle arrest; IBA:RefGenome.::GO:0080010; P:regulation of oxygen and reactive oxygen species metabolic process; IBA:RefGenome.::GO:0046578; P:regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0009888; P:tissue development; IBA:RefGenome.::GO:0001570; P:vasculogenesis; IBA:RefGenome. | 194 | Q3BJS1 | 506 | FOXN4_XENLA Forkhead box protein N4 OS=Xenopu... | 96 | 0.000000000003 | 73.2 | 40 | 57 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 195 | Q08050 | 763 | FOXM1_HUMAN Forkhead box protein M1 OS=Homo s... | 87 | 0.000000000006 | 72.8 | 41 | 55 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0003677; F:DNA binding; TAS:UniProtKB.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0019904; F:protein domain specific binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007049; P:cell cycle; TAS:UniProtKB.::GO:0006978; P:DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; IMP:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000086; P:G2/M transition of mitotic cell cycle; IDA:UniProtKB.::GO:0001889; P:liver development; IBA:RefGenome.::GO:0090344; P:negative regulation of cell aging; IMP:UniProtKB.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:2000781; P:positive regulation of double-strand break repair; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0071156; P:regulation of cell cycle arrest; IMP:BHF-UCL.::GO:0001558; P:regulation of cell growth; TAS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; NAS:UniProtKB.::GO:0080010; P:regulation of oxygen and reactive oxygen species metabolic process; IBA:RefGenome.::GO:0046578; P:regulation of Ras protein signal transduction; IMP:BHF-UCL.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:BHF-UCL.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0001570; P:vasculogenesis; IBA:RefGenome. | 196 | Q9WVH3 | 505 | FOXO4_MOUSE Forkhead box protein O4 OS=Mus mu... | 123 | 0.00000000001 | 71.6 | 35 | 54 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; ISS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0000080; P:G1 phase of mitotic cell cycle; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IDA:MGI.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 197 | O16850 | 541 | FOXO_CAEEL Forkhead box protein O OS=Caenorha... | 83 | 0.00000000002 | 70.9 | 41 | 63 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0033613; F:activating transcription factor binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB. | | | | | | | | | | GO:0034605; P:cellular response to heat; IDA:UniProtKB.::GO:0008340; P:determination of adult lifespan; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060537; P:muscle tissue development; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:UniProtKB.::GO:0002821; P:positive regulation of adaptive immune response; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0010564; P:regulation of cell cycle process; IEP:UniProtKB.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; IMP:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0046890; P:regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0009411; P:response to UV; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 198 | Q5W1J6 | 759 | FOXM1_XENLA Forkhead box protein M1 OS=Xenopu... | 87 | 0.00000000002 | 71.2 | 39 | 57 | GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 199 | B4MB78 | 609 | FOXO_DROVI Forkhead box protein O OS=Drosophi... | 83 | 0.00000000002 | 70.9 | 42 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 200 | B4KBF6 | 563 | FOXO_DROMO Forkhead box protein O OS=Drosophi... | 83 | 0.00000000002 | 70.5 | 42 | 61 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 201 | P98177 | 505 | FOXO4_HUMAN Forkhead box protein O4 OS=Homo s... | 81 | 0.00000000005 | 69.3 | 41 | 62 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0000080; P:G1 phase of mitotic cell cycle; IDA:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IDA:UniProtKB.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IBA:RefGenome.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051151; P:negative regulation of smooth muscle cell differentiation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009888; P:tissue development; IBA:RefGenome. | 202 | B4HF64 | 609 | FOXO_DROSE Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.6 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 203 | B4PTD3 | 628 | FOXO_DROYA Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 204 | B3P0K6 | 615 | FOXO_DROER Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 205 | Q95V55 | 613 | FOXO_DROME Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0010843; F:promoter binding; IBA:RefGenome.::GO:0019901; F:protein kinase binding; IBA:RefGenome.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:FlyBase.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0003704; F:specific RNA polymerase II transcription factor activity; IBA:RefGenome.::GO:0016566; F:specific transcriptional repressor activity; IBA:RefGenome.::GO:0016563; F:transcription activator activity; IBA:RefGenome.::GO:0008134; F:transcription factor binding; IBA:RefGenome. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034599; P:cellular response to oxidative stress; IMP:FlyBase.::GO:0009267; P:cellular response to starvation; IMP:FlyBase.::GO:0001745; P:compound eye morphogenesis; IMP:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0042593; P:glucose homeostasis; IMP:UniProtKB.::GO:0005977; P:glycogen metabolic process; IMP:FlyBase.::GO:0008286; P:insulin receptor signaling pathway; IGI:FlyBase.::GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0045792; P:negative regulation of cell size; IMP:FlyBase.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:FlyBase.::GO:0040027; P:negative regulation of vulval development; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0019216; P:regulation of lipid metabolic process; IMP:UniProtKB.::GO:0016241; P:regulation of macroautophagy; IMP:FlyBase.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0009617; P:response to bacterium; IMP:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0009888; P:tissue development; IBA:RefGenome. | 206 | Q6EUW1 | 657 | FOXO3_XENLA Forkhead box protein O3 OS=Xenopu... | 97 | 0.0000000001 | 68.2 | 39 | 58 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0019901; F:protein kinase binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 207 | B4G4S8 | 629 | FOXO_DROPE Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 208 | B3LYS5 | 600 | FOXO_DROAN Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 209 | O70220 | 400 | FOXQ1_MOUSE Forkhead box protein Q1 OS=Mus mu... | 81 | 0.0000000001 | 67.4 | 40 | 56 | GO:0005667; C:transcription factor complex; IBA:RefGenome. | | | | | | | | | | GO:0043028; F:cysteine-type endopeptidase regulator activity involved in apoptotic process; IBA:RefGenome.::GO:0008301; F:DNA binding, bending; IBA:RefGenome.::GO:0003690; F:double-stranded DNA binding; IBA:RefGenome.::GO:0030331; F:estrogen receptor binding; IBA:RefGenome.::GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IBA:RefGenome.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0008134; F:transcription factor binding; IBA:RefGenome.::GO:0031624; F:ubiquitin conjugating enzyme binding; IBA:RefGenome. | | | | | | | | | | GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; IBA:RefGenome.::GO:0009790; P:embryo development; IBA:RefGenome.::GO:0031069; P:hair follicle morphogenesis; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0007389; P:pattern specification process; IBA:RefGenome.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; IBA:RefGenome.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IBA:RefGenome.::GO:0051090; P:regulation of sequence-specific DNA binding transcription factor activity; IBA:RefGenome. | 210 | B4NFR1 | 628 | FOXO_DROWI Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 211 | Q298W7 | 644 | FOXO_DROPS Forkhead box protein O OS=Drosophi... | 83 | 0.0000000001 | 68.2 | 41 | 60 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0042593; P:glucose homeostasis; ISS:UniProtKB.::GO:0010259; P:multicellular organismal aging; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0019216; P:regulation of lipid metabolic process; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
