| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | O88501 | 641 | CAN6_RAT Calpain-6 OS=Rattus norvegicus (Rat)... | 300 | 0.000002 | 55.5 | 25 | 40 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008017; F:microtubule binding; ISS:UniProtKB. | | | | | | | | | | GO:0001578; P:microtubule bundle formation; ISS:UniProtKB.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0051493; P:regulation of cytoskeleton organization; ISS:UniProtKB. | 62 | O35646 | 641 | CAN6_MOUSE Calpain-6 OS=Mus musculus (Mouse).... | 300 | 0.000002 | 55.1 | 25 | 40 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008017; F:microtubule binding; IDA:UniProtKB. | | | | | | | | | | GO:0001578; P:microtubule bundle formation; IMP:UniProtKB.::GO:0006508; P:proteolysis; IEA:InterPro.::GO:0051493; P:regulation of cytoskeleton organization; IMP:UniProtKB. | 63 | Q9GLG7 | 815 | CAN3_MACFA Calpain-3 OS=Macaca fascicularis (... | 396 | 0.000004 | 54.3 | 23 | 36 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0030315; C:T-tubule; ISS:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0055103; F:ligase regulator activity; ISS:UniProtKB.::GO:0032947; F:protein complex scaffold; ISS:UniProtKB.::GO:0031402; F:sodium ion binding; ISS:UniProtKB.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB.::GO:0031432; F:titin binding; ISS:UniProtKB. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071472; P:cellular response to salt stress; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0033234; P:negative regulation of protein sumoylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0014718; P:positive regulation of satellite cell activation involved in skeletal muscle regeneration; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0014850; P:response to muscle activity; ISS:UniProtKB.::GO:0045214; P:sarcomere organization; ISS:UniProtKB.::GO:0097264; P:self proteolysis; ISS:UniProtKB. | 64 | Q95LP4 | 653 | CAN10_MACFA Calpain-10 OS=Macaca fascicularis... | 202 | 0.000005 | 53.9 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 65 | P20807 | 821 | CAN3_HUMAN Calpain-3 OS=Homo sapiens (Human).... | 435 | 0.000008 | 53.5 | 23 | 35 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0030315; C:T-tubule; ISS:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0055103; F:ligase regulator activity; IDA:UniProtKB.::GO:0032947; F:protein complex scaffold; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; TAS:ProtInc.::GO:0031402; F:sodium ion binding; ISS:UniProtKB.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB.::GO:0031432; F:titin binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071472; P:cellular response to salt stress; ISS:UniProtKB.::GO:0046716; P:muscle cell homeostasis; TAS:UniProtKB.::GO:0007517; P:muscle organ development; TAS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0033234; P:negative regulation of protein sumoylation; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0014718; P:positive regulation of satellite cell activation involved in skeletal muscle regeneration; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0014850; P:response to muscle activity; ISS:UniProtKB.::GO:0045214; P:sarcomere organization; ISS:UniProtKB.::GO:0097264; P:self proteolysis; IDA:UniProtKB. | 66 | Q9TTH8 | 822 | CAN3_SHEEP Calpain-3 OS=Ovis aries (Sheep). G... | 400 | 0.00001 | 53.1 | 24 | 37 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; ISS:UniProtKB.::GO:0030315; C:T-tubule; ISS:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; ISS:UniProtKB.::GO:0055103; F:ligase regulator activity; ISS:UniProtKB.::GO:0032947; F:protein complex scaffold; ISS:UniProtKB.::GO:0031402; F:sodium ion binding; ISS:UniProtKB.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB.::GO:0031432; F:titin binding; ISS:UniProtKB. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; ISS:UniProtKB.::GO:0071472; P:cellular response to salt stress; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0033234; P:negative regulation of protein sumoylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0051281; P:positive regulation of release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0014718; P:positive regulation of satellite cell activation involved in skeletal muscle regeneration; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006461; P:protein complex assembly; ISS:UniProtKB.::GO:0072657; P:protein localization in membrane; ISS:UniProtKB.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; ISS:UniProtKB.::GO:0014850; P:response to muscle activity; ISS:UniProtKB.::GO:0045214; P:sarcomere organization; ISS:UniProtKB.::GO:0097264; P:self proteolysis; ISS:UniProtKB. | 67 | Q6FJ28 | 713 | PALB_CANGA Calpain-like protease palB/RIM13 O... | 307 | 0.00001 | 53.1 | 22 | 41 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 68 | Q9HC96 | 672 | CAN10_HUMAN Calpain-10 OS=Homo sapiens (Human... | 202 | 0.00002 | 51.6 | 26 | 45 | GO:0005829; C:cytosol; ISS:BHF-UCL.::GO:0005886; C:plasma membrane; ISS:BHF-UCL. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IMP:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; ISS:BHF-UCL.::GO:0000149; F:SNARE binding; ISS:BHF-UCL. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:BHF-UCL.::GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0032024; P:positive regulation of insulin secretion; IMP:BHF-UCL.::GO:0032388; P:positive regulation of intracellular transport; ISS:BHF-UCL.::GO:0006508; P:proteolysis; IMP:BHF-UCL. | 69 | Q9ER56 | 720 | CAN12_MOUSE Calpain-12 OS=Mus musculus (Mouse... | 264 | 0.00006 | 50.4 | 23 | 41 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 70 | Q9ES66 | 666 | CAN10_RAT Calpain-10 OS=Rattus norvegicus (Ra... | 191 | 0.00006 | 50.4 | 27 | 45 | GO:0005938; C:cell cortex; IDA:RGD.::GO:0005856; C:cytoskeleton; IDA:RGD.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005792; C:microsome; IDA:RGD.::GO:0005743; C:mitochondrial inner membrane; IDA:RGD.::GO:0005758; C:mitochondrial intermembrane space; IDA:RGD.::GO:0005759; C:mitochondrial matrix; IDA:RGD.::GO:0005741; C:mitochondrial outer membrane; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:BHF-UCL. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; NAS:BHF-UCL.::GO:0008092; F:cytoskeletal protein binding; IDA:BHF-UCL.::GO:0000149; F:SNARE binding; IDA:BHF-UCL. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:RGD.::GO:0007568; P:aging; IDA:RGD.::GO:0006508; P:proteolysis; IDA:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0031667; P:response to nutrient levels; IDA:RGD. | 71 | Q9ESK3 | 666 | CAN10_MOUSE Calpain-10 OS=Mus musculus (Mouse... | 202 | 0.00006 | 50.4 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IMP:BHF-UCL.::GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0032388; P:positive regulation of intracellular transport; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 72 | Q9VXH6 | 681 | CANC_DROME Calpain-C OS=Drosophila melanogast... | 308 | 0.0007 | 47 | 24 | 43 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | | 73 | Q759K3 | 694 | PALB_ASHGO Calpain-like protease palB/RIM13 O... | 260 | 0.002 | 45.4 | 24 | 38 | | | | | | | | | | | GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 74 | Q8MUF9 | 649 | CPLA_DICDI Putative calpain-like cysteine pro... | 63 | 0.69 | 37.4 | 37 | 54 | GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:dictyBase. | | | | | | | | | | GO:0004198; F:calcium-dependent cysteine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 75 | Q55FS2 | 1105 | STK4L_DICDI Serine/threonine-protein kinase 4... | 79 | 2 | 35.8 | 29 | 46 | GO:0005737; C:cytoplasm; ISS:dictyBase.::GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:dictyBase.::GO:0008283; P:cell proliferation; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase. | 76 | A4VNX4 | 382 | RLMN_PSEU5 Ribosomal RNA large subunit methyl... | 82 | 3.4 | 34.7 | 37 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070040; F:rRNA (adenine-C2-)-methyltransferase activity; IEA:EC. | | | | | | | | | | | 77 | Q51385 | 379 | RLMN_PSEAE Ribosomal RNA large subunit methyl... | 82 | 4.3 | 34.3 | 37 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070040; F:rRNA (adenine-C2-)-methyltransferase activity; IEA:EC. | | | | | | | | | | | 78 | Q02RW0 | 379 | RLMN_PSEAB Ribosomal RNA large subunit methyl... | 82 | 4.3 | 34.3 | 37 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0070040; F:rRNA (adenine-C2-)-methyltransferase activity; IEA:EC. | | | | | | | | | | | 79 | O70022 | 1092 | FBE_STAEP Fibrinogen-binding protein OS=Staph... | 53 | 4.3 | 34.7 | 38 | 53 | GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW. |
