rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q7Z6E9 | 1792 | RBBP6_HUMAN E3 ubiquitin-protein ligase RBBP6... | 70 | 0.000008 | 53.5 | 33 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB. | 2 | P97868 | 1790 | RBBP6_MOUSE E3 ubiquitin-protein ligase RBBP6... | 70 | 0.000008 | 53.1 | 33 | 47 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 3 | O94264 | 482 | YORF_SCHPO Uncharacterized RING finger protei... | 70 | 0.00001 | 52 | 37 | 51 | GO:0005847; C:mRNA cleavage and polyadenylation specificity factor complex; ISS:PomBase. | | | | | | | | | | GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006379; P:mRNA cleavage; ISS:PomBase.::GO:0006378; P:mRNA polyadenylation; ISS:PomBase.::GO:0016567; P:protein ubiquitination; NAS:PomBase. | 4 | Q99728 | 777 | BARD1_HUMAN BRCA1-associated RING domain prot... | 229 | 0.016 | 42.4 | 23 | 38 | GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB. | 5 | Q197D9 | 206 | VF193_IIV3 Putative apoptosis inhibitor 021L ... | 64 | 0.11 | 38.5 | 31 | 44 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 6 | O01761 | 8081 | UNC89_CAEEL Muscle M-line assembly protein un... | 161 | 0.53 | 37.7 | 24 | 39 | GO:0005887; C:integral to plasma membrane; IEA:InterPro.::GO:0031430; C:M band; IDA:WormBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0019902; F:phosphatase binding; IPI:WormBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017048; F:Rho GTPase binding; IPI:WormBase.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:WormBase.::GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro. | | | | | | | | | | GO:0040011; P:locomotion; IMP:WormBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030241; P:skeletal muscle myosin thick filament assembly; IMP:WormBase.::GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. | 7 | Q9QZH2 | 768 | BARD1_RAT BRCA1-associated RING domain protei... | 66 | 0.76 | 37 | 33 | 50 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; IEP:RGD. | 8 | Q803C1 | 485 | RNF8_DANRE E3 ubiquitin-protein ligase RNF8 O... | 58 | 0.8 | 36.6 | 34 | 52 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 9 | Q7M3S9 | 943 | RNGB_DICDI RING finger protein B OS=Dictyoste... | 36 | 1.2 | 36.2 | 42 | 53 | GO:0005737; C:cytoplasm; TAS:dictyBase. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 10 | Q54DH8 | 2310 | TAF1_DICDI Transcription initiation factor TF... | 116 | 5.5 | 34.3 | 24 | 33 | GO:0005669; C:transcription factor TFIID complex; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004402; F:histone acetyltransferase activity; ISS:dictyBase. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:dictyBase.::GO:0006461; P:protein complex assembly; ISS:dictyBase.::GO:0006468; P:protein phosphorylation; ISS:dictyBase.::GO:0000114; P:regulation of transcription involved in G1 phase of mitotic cell cycle; ISS:dictyBase. | 11 | P09560 | 638 | RAF1_XENLA RAF proto-oncogene serine/threonin... | 33 | 1.4 | 35.8 | 39 | 52 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 12 | Q94AY3 | 420 | DRIP2_ARATH E3 ubiquitin protein ligase DRIP2... | 93 | 2.5 | 35 | 28 | 46 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0009414; P:response to water deprivation; IGI:TAIR. | 13 | Q8IWZ5 | 723 | TRI42_HUMAN Tripartite motif-containing prote... | 70 | 3.6 | 34.7 | 30 | 50 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 14 | D3ZDI6 | 445 | MYLIP_RAT E3 ubiquitin-protein ligase MYLIP O... | 38 | 3.8 | 34.3 | 42 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0019898; C:extrinsic to membrane; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 15 | Q5ZIJ9 | 954 | MIB2_CHICK E3 ubiquitin-protein ligase MIB2 O... | 51 | 3.8 | 34.7 | 27 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IEA:UniProtKB-KW. | 16 | Q63HN8 | 5207 | RN213_HUMAN E3 ubiquitin-protein ligase RNF21... | 168 | 4.5 | 34.7 | 23 | 35 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0051865; P:protein autoubiquitination; IDA:UniProtKB. | 17 | Q8WY64 | 445 | MYLIP_HUMAN E3 ubiquitin-protein ligase MYLIP... | 38 | 4.9 | 34.3 | 42 | 55 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0019898; C:extrinsic to membrane; IEA:InterPro. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006928; P:cellular component movement; IMP:UniProtKB.::GO:0007399; P:nervous system development; IMP:UniProtKB. | 18 | Q99N57 | 648 | RAF1_MOUSE RAF proto-oncogene serine/threonin... | 33 | 6.4 | 33.9 | 36 | 48 | GO:0005829; C:cytosol; TAS:MGI.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0031143; C:pseudopodium; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017016; F:Ras GTPase binding; IPI:MGI. | | | | | | | | | | GO:0006915; P:apoptotic process; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI. | 19 | O23212 | 573 | U2A2A_ARATH Splicing factor U2af large subuni... | 101 | 8.2 | 33.5 | 32 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0042742; P:defense response to bacterium; IEP:TAIR.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 20 | O70445 | 765 | BARD1_MOUSE BRCA1-associated RING domain prot... | 77 | 8.5 | 33.5 | 31 | 47 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB. | 21 | Q9H9P5 | 680 | UNKL_HUMAN Putative E3 ubiquitin-protein liga... | 53 | 9.3 | 33.5 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 22 | B2RWS6 | 2415 | EP300_MOUSE Histone acetyltransferase p300 OS... | 100 | 9.7 | 33.5 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000123; C:histone acetyltransferase complex; IEA:InterPro.::GO:0005667; C:transcription factor complex; IDA:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0004402; F:histone acetyltransferase activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IMP:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0051216; P:cartilage development; NAS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0043967; P:histone H4 acetylation; ISS:UniProtKB.::GO:0018076; P:N-terminal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043627; P:response to estrogen stimulus; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |