rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q9H1R2 | 295 | DUS15_HUMAN Dual specificity protein phosphat... | 140 | 0.0000003 | 56.6 | 31 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 62 | Q8TE77 | 659 | SSH3_HUMAN Protein phosphatase Slingshot homo... | 152 | 0.0000003 | 57.4 | 30 | 49 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0008064; P:regulation of actin polymerization or depolymerization; IBA:RefGenome.::GO:0050770; P:regulation of axonogenesis; IBA:RefGenome.::GO:0010591; P:regulation of lamellipodium assembly; IBA:RefGenome. | 63 | Q5RD73 | 185 | DUS3_PONAB Dual specificity protein phosphata... | 146 | 0.0000003 | 54.7 | 32 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 64 | P51452 | 185 | DUS3_HUMAN Dual specificity protein phosphata... | 146 | 0.0000003 | 54.7 | 32 | 48 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0001772; C:immunological synapse; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IMP:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0050868; P:negative regulation of T cell activation; IDA:UniProtKB.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 65 | Q60969 | 223 | STYX_MOUSE Serine/threonine/tyrosine-interact... | 116 | 0.0000005 | 54.7 | 27 | 52 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 66 | Q9NRW4 | 184 | DUS22_HUMAN Dual specificity protein phosphat... | 161 | 0.0000005 | 53.9 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000188; P:inactivation of MAPK activity; TAS:ProtInc.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 67 | Q55CS7 | 834 | MPL1_DICDI MAP kinase phosphatase with leucin... | 148 | 0.0000005 | 57 | 31 | 45 | GO:0005576; C:extracellular region; IC:dictyBase. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IMP:dictyBase. | | | | | | | | | | GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase. | 68 | Q75QN6 | 929 | PHS1_ARATH Dual specificity protein phosphata... | 50 | 2.5 | 35 | 36 | 52 | GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043622; P:cortical microtubule organization; IMP:TAIR.::GO:0010468; P:regulation of gene expression; IMP:TAIR.::GO:0010119; P:regulation of stomatal movement; IMP:TAIR.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR. | 69 | Q9D7X3 | 185 | DUS3_MOUSE Dual specificity protein phosphata... | 123 | 0.0000008 | 53.5 | 33 | 49 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005654; C:nucleoplasm; IBA:RefGenome. | | | | | | | | | | GO:0033549; F:MAP kinase phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IDA:MGI. | | | | | | | | | | GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IBA:RefGenome.::GO:0046329; P:negative regulation of JNK cascade; IBA:RefGenome.::GO:0050868; P:negative regulation of T cell activation; IBA:RefGenome.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IBA:RefGenome.::GO:0045931; P:positive regulation of mitotic cell cycle; IBA:RefGenome. | 70 | Q55CS8 | 695 | MPL2_DICDI MAP kinase phosphatase with leucin... | 145 | 0.0000008 | 56.2 | 30 | 46 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 71 | Q8VE01 | 188 | DUS18_MOUSE Dual specificity protein phosphat... | 155 | 0.000002 | 52.4 | 28 | 50 | GO:0031314; C:extrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0031304; C:intrinsic to mitochondrial inner membrane; ISS:MGI.::GO:0005758; C:mitochondrial intermembrane space; ISS:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006612; P:protein targeting to membrane; ISS:MGI.::GO:0006626; P:protein targeting to mitochondrion; ISS:MGI.::GO:0046677; P:response to antibiotic; ISS:MGI. | 72 | Q17QJ3 | 211 | DUS26_BOVIN Dual specificity protein phosphat... | 149 | 0.000005 | 51.6 | 31 | 46 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 73 | Q9UNI6 | 340 | DUS12_HUMAN Dual specificity protein phosphat... | 53 | 0.000006 | 52.8 | 47 | 60 | GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0033133; P:positive regulation of glucokinase activity; IBA:RefGenome. | 74 | Q9BV47 | 211 | DUS26_HUMAN Dual specificity protein phosphat... | 149 | 0.000006 | 51.2 | 31 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 75 | Q5R6H6 | 211 | DUS26_PONAB Dual specificity protein phosphat... | 149 | 0.000007 | 51.2 | 31 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 76 | Q566R7 | 183 | DS22B_DANRE Dual specificity protein phosphat... | 128 | 0.000007 | 50.4 | 29 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 77 | Q8K4T5 | 220 | DUS19_MOUSE Dual specificity protein phosphat... | 119 | 0.000008 | 51.2 | 29 | 49 | | | | | | | | | | | GO:0005078; F:MAP-kinase scaffold activity; IDA:BHF-UCL.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.::GO:0030295; F:protein kinase activator activity; IDA:BHF-UCL.::GO:0004860; F:protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0046329; P:negative regulation of JNK cascade; IDA:BHF-UCL.::GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL.::GO:0046330; P:positive regulation of JNK cascade; IDA:BHF-UCL.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:BHF-UCL. | 78 | P38590 | 489 | MSG5_YEAST Tyrosine-protein phosphatase MSG5 ... | 82 | 0.000008 | 52.8 | 30 | 52 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IMP:SGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0060237; P:regulation of fungal-type cell wall organization; IMP:SGD.::GO:0071701; P:regulation of MAPK export from nucleus; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome. | 79 | Q5XHB2 | 209 | DUS22_XENTR Dual specificity protein phosphat... | 143 | 0.000009 | 50.8 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0046330; P:positive regulation of JNK cascade; IBA:RefGenome.::GO:0042127; P:regulation of cell proliferation; IBA:RefGenome.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; IBA:RefGenome. | 80 | Q9D700 | 211 | DUS26_MOUSE Dual specificity protein phosphat... | 149 | 0.000009 | 50.8 | 30 | 44 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; ISS:MGI. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 81 | Q5RDP3 | 223 | STYX_PONAB Serine/threonine/tyrosine-interact... | 92 | 0.00001 | 50.8 | 29 | 52 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 82 | Q8WUJ0 | 223 | STYX_HUMAN Serine/threonine/tyrosine-interact... | 92 | 0.00001 | 50.8 | 29 | 52 | GO:0005737; C:cytoplasm; IBA:RefGenome. | | | | | | | | | | GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007283; P:spermatogenesis; IBA:RefGenome. | 83 | Q4V7N3 | 223 | STYXA_XENLA Serine/threonine/tyrosine-interac... | 92 | 0.00001 | 50.4 | 28 | 53 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 84 | Q5FVI9 | 211 | DUS26_RAT Dual specificity protein phosphatas... | 149 | 0.00001 | 50.1 | 30 | 44 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | | 85 | Q5U593 | 223 | STYXB_XENLA Serine/threonine/tyrosine-interac... | 92 | 0.00001 | 50.4 | 28 | 53 | | | | | | | | | | | GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006470; P:protein dephosphorylation; IEA:InterPro. | 86 | Q39491 | 276 | PTP3_CHLMO Dual specificity protein phosphata... | 130 | 0.00001 | 50.8 | 28 | 47 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 87 | Q6GQJ8 | 209 | DUS22_XENLA Dual specificity protein phosphat... | 143 | 0.00002 | 50.1 | 30 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 88 | P43078 | 597 | PTPX_CANAW Probable tyrosine-protein phosphat... | 114 | 0.00002 | 51.2 | 25 | 48 | | | | | | | | | | | GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro. | | | | | | | | | | | 89 | Q9H596 | 190 | DUS21_HUMAN Dual specificity protein phosphat... | 58 | 0.00002 | 48.9 | 40 | 69 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB. | | | | | | | | | | | 90 | Q5BIP9 | 188 | DUS18_BOVIN Dual specificity protein phosphat... | 155 | 0.00004 | 48.5 | 28 | 47 | GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC. | | | | | | | | | | | 91 | P40479 | 209 | SDP1_YEAST Dual-specificity protein phosphata... | 63 | 0.00005 | 48.5 | 35 | 60 | GO:0005829; C:cytosol; IBA:RefGenome.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0033550; F:MAP kinase tyrosine phosphatase activity; IDA:SGD.::GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome. | | | | | | | | | | GO:0000754; P:adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion; IBA:RefGenome.::GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IBA:RefGenome. |