| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | A4QPH2 | 592 | PI4P2_HUMAN Putative phosphatidylinositol 4-k... | 259 | 2e-22 | 107 | 28 | 47 | | | | | | | | | | | GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 62 | Q9UW20 | 977 | PIK1_CANAL Phosphatidylinositol 4-kinase PIK1... | 217 | 2e-22 | 107 | 31 | 48 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 63 | Q9UW24 | 956 | PIK1A_CANAL Phosphatidylinositol 4-kinase PIK... | 210 | 5e-21 | 103 | 31 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004430; F:1-phosphatidylinositol 4-kinase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro.::GO:0044011; P:single-species biofilm formation on inanimate substrate; IMP:CGD. | 64 | Q9C680 | 525 | P4KA2_ARATH Phosphatidylinositol 4-kinase alp... | 261 | 1e-18 | 94.4 | 31 | 46 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004430; F:1-phosphatidylinositol 4-kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 65 | P38110 | 2787 | ATM_YEAST Serine/threonine-protein kinase TEL... | 242 | 0.000000000000004 | 84.3 | 29 | 44 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0042162; F:telomeric DNA binding; IDA:SGD. | | | | | | | | | | GO:0006975; P:DNA damage induced protein phosphorylation; IMP:SGD.::GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0016572; P:histone phosphorylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD. | 66 | Q54ER4 | 3157 | ATR1_DICDI Probable serine/threonine-protein ... | 278 | 0.00000000000009 | 80.1 | 23 | 43 | GO:0005634; C:nucleus; ISS:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000075; P:cell cycle checkpoint; ISS:dictyBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0042770; P:signal transduction in response to DNA damage; ISS:dictyBase. | 67 | Q9VXG8 | 2517 | ATR_DROME Serine/threonine-protein kinase ATR... | 264 | 0.0000000000008 | 76.6 | 24 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007349; P:cellularization; TAS:FlyBase.::GO:0030261; P:chromosome condensation; IGI:FlyBase.::GO:0000076; P:DNA replication checkpoint; IMP:FlyBase.::GO:0045002; P:double-strand break repair via single-strand annealing; IMP:FlyBase.::GO:0045003; P:double-strand break repair via synthesis-dependent strand annealing; IMP:FlyBase.::GO:0001700; P:embryonic development via the syncytial blastoderm; TAS:FlyBase.::GO:0016321; P:female meiosis chromosome segregation; IMP:FlyBase.::GO:0007444; P:imaginal disc development; TAS:FlyBase.::GO:0007133; P:meiotic anaphase I; IMP:FlyBase.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IMP:FlyBase.::GO:0048477; P:oogenesis; TAS:FlyBase.::GO:0007131; P:reciprocal meiotic recombination; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0007348; P:regulation of syncytial blastoderm mitotic cell cycle; TAS:FlyBase.::GO:0009314; P:response to radiation; TAS:FlyBase.::GO:0000723; P:telomere maintenance; IGI:FlyBase. | 68 | Q86C65 | 2380 | TOR_DICDI Target of rapamycin OS=Dictyosteliu... | 285 | 0.000000000002 | 75.1 | 25 | 43 | GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; IEA:UniProtKB-KW. | 69 | Q2U639 | 2925 | ATM_ASPOR Serine/threonine-protein kinase tel... | 279 | 0.000000000003 | 75.1 | 27 | 42 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 70 | Q4WVM7 | 2796 | ATM_ASPFU Serine/threonine-protein kinase tel... | 263 | 0.000000000003 | 75.1 | 28 | 42 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 71 | Q5BHE2 | 2793 | ATM_EMENI Serine/threonine-protein kinase tel... | 267 | 0.000000000006 | 73.9 | 26 | 43 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 72 | Q6PQD5 | 3057 | ATM_PIG Serine-protein kinase ATM OS=Sus scro... | 320 | 0.000000000006 | 73.9 | 21 | 39 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005840; C:ribosome; IEA:InterPro. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.::GO:0006412; P:translation; IEA:InterPro. | 73 | Q10366 | 851 | YDBG_SCHPO Uncharacterized PI3/PI4-kinase fam... | 216 | 0.000000000006 | 73.6 | 25 | 48 | GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0005634; C:nucleus; ISS:PomBase. | | | | | | | | | | GO:0004430; F:1-phosphatidylinositol 4-kinase activity; ISS:PomBase.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:PomBase.::GO:0048015; P:phosphatidylinositol-mediated signaling; IEA:InterPro. | 74 | P42346 | 2549 | MTOR_RAT Serine/threonine-protein kinase mTOR... | 305 | 0.000000000008 | 73.6 | 24 | 40 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0070438; C:mTOR-FKBP12-rapamycin complex; IDA:RGD.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0031931; C:TORC1 complex; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:RGD.::GO:0045792; P:negative regulation of cell size; IMP:MGI.::GO:0001938; P:positive regulation of endothelial cell proliferation; IMP:RGD.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0051897; P:positive regulation of protein kinase B signaling cascade; IMP:RGD.::GO:0045727; P:positive regulation of translation; IMP:RGD.::GO:0046777; P:protein autophosphorylation; IMP:RGD.::GO:0043610; P:regulation of carbohydrate utilization; IDA:RGD.::GO:0031998; P:regulation of fatty acid beta-oxidation; IDA:RGD.::GO:0005979; P:regulation of glycogen biosynthetic process; IDA:RGD.::GO:0032095; P:regulation of response to food; IDA:RGD. | 75 | Q62388 | 3066 | ATM_MOUSE Serine-protein kinase ATM OS=Mus mu... | 320 | 0.000000000009 | 73.6 | 23 | 39 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0047485; F:protein N-terminus binding; ISS:UniProtKB. | | | | | | | | | | GO:0007420; P:brain development; IGI:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0006281; P:DNA repair; IDA:MGI.::GO:0007292; P:female gamete generation; IMP:MGI.::GO:0007507; P:heart development; IGI:MGI.::GO:0071044; P:histone mRNA catabolic process; ISS:UniProtKB.::GO:0042159; P:lipoprotein catabolic process; IGI:MGI.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0051402; P:neuron apoptotic process; IGI:MGI.::GO:0043525; P:positive regulation of neuron apoptotic process; IGI:MGI.::GO:0002331; P:pre-B cell allelic exclusion; IMP:UniProtKB.::GO:0001756; P:somitogenesis; IGI:MGI. | 76 | Q9FR53 | 2481 | TOR_ARATH Serine/threonine-protein kinase TOR... | 287 | 0.00000000001 | 73.2 | 25 | 39 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0043621; F:protein self-association; IPI:TAIR.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0000975; F:regulatory region DNA binding; IDA:UniProtKB. | | | | | | | | | | GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0010507; P:negative regulation of autophagy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IGI:UniProtKB.::GO:0040019; P:positive regulation of embryonic development; IMP:UniProtKB.::GO:2000234; P:positive regulation of rRNA processing; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0009303; P:rRNA transcription; IMP:TAIR. | 77 | Q9JLN9 | 2549 | MTOR_MOUSE Serine/threonine-protein kinase mT... | 289 | 0.00000000002 | 72.8 | 24 | 41 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB. | | | | | | | | | | GO:0071456; P:cellular response to hypoxia; IDA:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; IDA:UniProtKB.::GO:0007281; P:germ cell development; IDA:MGI.::GO:0045792; P:negative regulation of cell size; IGI:MGI.::GO:0016242; P:negative regulation of macroautophagy; IMP:MGI.::GO:0051534; P:negative regulation of NFAT protein import into nucleus; IMP:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:MGI.::GO:0010592; P:positive regulation of lamellipodium assembly; IDA:MGI.::GO:0046889; P:positive regulation of lipid biosynthetic process; ISS:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051496; P:positive regulation of stress fiber assembly; IDA:MGI.::GO:0045859; P:regulation of protein kinase activity; IGI:MGI.::GO:0032314; P:regulation of Rac GTPase activity; IMP:MGI.::GO:0043200; P:response to amino acid stimulus; IDA:MGI.::GO:0032868; P:response to insulin stimulus; IDA:MGI.::GO:0031529; P:ruffle organization; IDA:MGI. | 78 | Q6BV76 | 2948 | ATM_DEBHA Serine/threonine-protein kinase TEL... | 286 | 0.00000000002 | 72.4 | 24 | 41 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 79 | Q9VK45 | 2470 | TOR_DROME Target of rapamycin OS=Drosophila m... | 289 | 0.00000000002 | 72.4 | 24 | 42 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; NAS:FlyBase.::GO:0043621; F:protein self-association; IDA:FlyBase. | | | | | | | | | | GO:0006914; P:autophagy; IMP:FlyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0048813; P:dendrite morphogenesis; IMP:FlyBase.::GO:0009594; P:detection of nutrient; TAS:FlyBase.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0032456; P:endocytic recycling; IDA:FlyBase.::GO:0008406; P:gonad development; IMP:FlyBase.::GO:0035264; P:multicellular organism growth; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; NAS:FlyBase.::GO:0045793; P:positive regulation of cell size; IMP:FlyBase.::GO:0040018; P:positive regulation of multicellular organism growth; TAS:FlyBase.::GO:0046622; P:positive regulation of organ growth; TAS:FlyBase.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:FlyBase.::GO:0090070; P:positive regulation of ribosome biogenesis; IMP:FlyBase.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IGI:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase. | 80 | Q6FX42 | 2379 | ATR_CANGA Serine/threonine-protein kinase MEC... | 296 | 0.00000000003 | 72 | 25 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 81 | P42345 | 2549 | MTOR_HUMAN Serine/threonine-protein kinase mT... | 289 | 0.00000000003 | 72 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.::GO:0005942; C:phosphatidylinositol 3-kinase complex; NAS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0031931; C:TORC1 complex; IDA:UniProtKB.::GO:0031932; C:TORC2 complex; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051219; F:phosphoprotein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0001030; F:RNA polymerase III type 1 promoter DNA binding; IDA:UniProtKB.::GO:0001031; F:RNA polymerase III type 2 promoter DNA binding; IDA:UniProtKB.::GO:0001032; F:RNA polymerase III type 3 promoter DNA binding; IDA:UniProtKB.::GO:0001156; F:TFIIIC-class transcription factor binding; IDA:UniProtKB. | | | | | | | | | | GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0071456; P:cellular response to hypoxia; ISS:UniProtKB.::GO:0031669; P:cellular response to nutrient levels; ISS:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0046889; P:positive regulation of lipid biosynthetic process; IMP:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0030163; P:protein catabolic process; TAS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IDA:UniProtKB.::GO:0007584; P:response to nutrient; NAS:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0031929; P:TOR signaling cascade; IMP:UniProtKB. | 82 | Q0DJS1 | 2465 | TOR_ORYSJ Serine/threonine-protein kinase TOR... | 286 | 0.00000000003 | 71.6 | 24 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 83 | Q95Q95 | 2697 | TOR_CAEEL Target of rapamycin homolog OS=Caen... | 257 | 0.00000000004 | 71.2 | 26 | 42 | GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro. | | | | | | | | | | GO:0000492; P:box C/D snoRNP assembly; IMP:WormBase.::GO:0043053; P:dauer entry; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006629; P:lipid metabolic process; IMP:WormBase.::GO:0045727; P:positive regulation of translation; IMP:WormBase.::GO:0009408; P:response to heat; IMP:WormBase.::GO:0031929; P:TOR signaling cascade; IMP:WormBase.::GO:0006412; P:translation; IMP:WormBase. | 84 | Q13315 | 3056 | ATM_HUMAN Serine-protein kinase ATM OS=Homo s... | 340 | 0.00000000005 | 70.9 | 23 | 39 | GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; IMP:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004677; F:DNA-dependent protein kinase activity; IDA:BHF-UCL.::GO:0032403; F:protein complex binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IDA:BHF-UCL.::GO:0047485; F:protein N-terminus binding; IDA:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IMP:BHF-UCL.::GO:0071480; P:cellular response to gamma radiation; IDA:BHF-UCL.::GO:0006975; P:DNA damage induced protein phosphorylation; IDA:BHF-UCL.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000724; P:double-strand break repair via homologous recombination; TAS:Reactome.::GO:0031572; P:G2/M transition DNA damage checkpoint; IMP:BHF-UCL.::GO:0071044; P:histone mRNA catabolic process; IDA:UniProtKB.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:UniProtKB.::GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.::GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IMP:BHF-UCL.::GO:0002331; P:pre-B cell allelic exclusion; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0007131; P:reciprocal meiotic recombination; TAS:ProtInc.::GO:0090399; P:replicative senescence; IMP:BHF-UCL. | 85 | Q6CAD2 | 2282 | ATM_YARLI Serine/threonine-protein kinase TEL... | 252 | 0.00000000006 | 70.5 | 25 | 41 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 86 | Q59LR2 | 2325 | ATR_CANAL Serine/threonine-protein kinase MEC... | 306 | 0.00000000008 | 70.5 | 23 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 87 | Q6FRZ9 | 2763 | ATM_CANGA Serine/threonine-protein kinase TEL... | 289 | 0.00000000008 | 70.1 | 26 | 42 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. | 88 | P38111 | 2368 | ATR_YEAST Serine/threonine-protein kinase MEC... | 278 | 0.0000000002 | 69.3 | 24 | 42 | GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005634; C:nucleus; IC:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0000077; P:DNA damage checkpoint; TAS:SGD.::GO:0006975; P:DNA damage induced protein phosphorylation; IMP:SGD.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IMP:SGD.::GO:0016572; P:histone phosphorylation; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0000722; P:telomere maintenance via recombination; IGI:SGD. | 89 | Q75DB8 | 2324 | ATR_ASHGO Serine/threonine-protein kinase MEC... | 261 | 0.0000000002 | 69.3 | 26 | 43 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 90 | Q9DE14 | 2654 | ATR_XENLA Serine/threonine-protein kinase atr... | 248 | 0.0000000003 | 68.6 | 24 | 47 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:UniProtKB. | 91 | Q7RZT9 | 2939 | ATM_NEUCR Serine/threonine-protein kinase tel... | 258 | 0.0000000004 | 68.2 | 24 | 41 | GO:0000781; C:chromosome, telomeric region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW. |
