| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | P97433 | 1693 | RGNEF_MOUSE Rho-guanine nucleotide exchange f... | 212 | 0.0001 | 50.4 | 23 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0021955; P:central nervous system neuron axonogenesis; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060052; P:neurofilament cytoskeleton organization; IMP:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 122 | Q58EX7 | 1191 | PKHG4_HUMAN Puratrophin-1 OS=Homo sapiens (Hu... | 291 | 0.0001 | 50.4 | 23 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 123 | Q9H7P9 | 1386 | PKHG2_HUMAN Pleckstrin homology domain-contai... | 168 | 0.0001 | 50.4 | 26 | 43 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 124 | A1IGU5 | 675 | ARH37_HUMAN Rho guanine nucleotide exchange f... | 189 | 0.0001 | 50.1 | 28 | 46 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 125 | Q09763 | 753 | GEF1_SCHPO Rho guanine nucleotide exchange fa... | 213 | 0.0001 | 50.1 | 22 | 48 | GO:0030428; C:cell septum; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:PomBase. | | | | | | | | | | GO:0000917; P:barrier septum assembly; IEA:UniProtKB-KW.::GO:0032488; P:Cdc42 protein signal transduction; NAS:PomBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032955; P:regulation of barrier septum assembly; IMP:PomBase.::GO:2000100; P:regulation of establishment or maintenance of bipolar cell polarity regulating cell shape; IMP:PomBase.::GO:0032319; P:regulation of Rho GTPase activity; IDA:PomBase. | 126 | O15068 | 1137 | MCF2L_HUMAN Guanine nucleotide exchange facto... | 206 | 0.0001 | 50.1 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 127 | Q7TT49 | 1713 | MRCKB_RAT Serine/threonine-protein kinase MRC... | 345 | 0.0001 | 50.1 | 19 | 41 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0017048; F:Rho GTPase binding; IDA:RGD.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 128 | Q15052 | 776 | ARHG6_HUMAN Rho guanine nucleotide exchange f... | 210 | 0.0002 | 49.7 | 24 | 43 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; NAS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0007254; P:JNK cascade; NAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 129 | O94887 | 1054 | FARP2_HUMAN FERM, RhoGEF and pleckstrin domai... | 317 | 0.0002 | 49.7 | 24 | 38 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0019898; C:extrinsic to membrane; IEA:InterPro. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0016322; P:neuron remodeling; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 130 | Q8AVG0 | 862 | ABR_XENLA Active breakpoint cluster region-re... | 409 | 0.0003 | 49.3 | 24 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 131 | P0C6P5 | 1700 | RGNEF_RAT Rho-guanine nucleotide exchange fac... | 206 | 0.0003 | 49.3 | 22 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 132 | Q80VK6 | 219 | ARH38_MOUSE Rho guanine nucleotide exchange f... | 96 | 0.0003 | 47.4 | 31 | 51 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 133 | Q80UW5 | 1551 | MRCKG_MOUSE Serine/threonine-protein kinase M... | 354 | 0.0003 | 49.3 | 23 | 38 | GO:0031252; C:cell leading edge; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 134 | A1L390 | 1219 | PKHG3_HUMAN Pleckstrin homology domain-contai... | 283 | 0.0003 | 49.3 | 25 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 135 | Q5XXR3 | 772 | ARHG6_RAT Rho guanine nucleotide exchange fac... | 210 | 0.0003 | 48.9 | 23 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 136 | Q6P720 | 579 | ARHGP_RAT Rho guanine nucleotide exchange fac... | 189 | 0.0004 | 48.1 | 24 | 47 | GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 137 | Q9NHV9 | 793 | VAV_DROME Protein vav OS=Drosophila melanogas... | 377 | 0.0005 | 48.1 | 20 | 40 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:FlyBase.::GO:0007015; P:actin filament organization; IMP:FlyBase.::GO:0007155; P:cell adhesion; IMP:FlyBase.::GO:0016477; P:cell migration; IMP:FlyBase.::GO:0007417; P:central nervous system development; IGI:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007520; P:myoblast fusion; IMP:FlyBase.::GO:0007424; P:open tracheal system development; IMP:FlyBase.::GO:0072499; P:photoreceptor cell axon guidance; IMP:FlyBase.::GO:0008360; P:regulation of cell shape; IMP:FlyBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 138 | Q64096 | 1149 | MCF2L_MOUSE Guanine nucleotide exchange facto... | 206 | 0.0007 | 47.8 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005545; F:1-phosphatidylinositol binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IDA:MGI. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007266; P:Rho protein signal transduction; IDA:MGI. | 139 | Q9CWR0 | 618 | ARHGP_MOUSE Rho guanine nucleotide exchange f... | 189 | 0.0007 | 47.8 | 23 | 46 | GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0030017; C:sarcomere; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 140 | Q8K4I3 | 771 | ARHG6_MOUSE Rho guanine nucleotide exchange f... | 210 | 0.0009 | 47.4 | 23 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 141 | P27671 | 1262 | RGRF1_MOUSE Ras-specific guanine nucleotide-r... | 256 | 0.001 | 47.4 | 21 | 42 | GO:0005829; C:cytosol; IDA:HGNC.::GO:0030426; C:growth cone; IDA:HGNC. | | | | | | | | | | GO:0035254; F:glutamate receptor binding; IPI:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; IDA:HGNC.::GO:0008283; P:cell proliferation; IMP:MGI.::GO:0031175; P:neuron projection development; IDA:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0048168; P:regulation of neuronal synaptic plasticity; IMP:MGI.::GO:0035020; P:regulation of Rac protein signal transduction; IDA:HGNC.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 142 | Q21653 | 1182 | YNG2_CAEEL Uncharacterized protein R02F2.2 OS... | 198 | 0.001 | 47.4 | 24 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 143 | P28818 | 1244 | RGRF1_RAT Ras-specific guanine nucleotide-rel... | 256 | 0.001 | 47.4 | 21 | 42 | GO:0005829; C:cytosol; ISS:HGNC.::GO:0030426; C:growth cone; ISS:HGNC. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005099; F:Ras GTPase activator activity; TAS:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0032863; P:activation of Rac GTPase activity; ISS:HGNC.::GO:0031175; P:neuron projection development; ISS:HGNC.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:UniProtKB.::GO:0035020; P:regulation of Rac protein signal transduction; ISS:HGNC.::GO:0048167; P:regulation of synaptic plasticity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 144 | Q6ZNL6 | 1462 | FGD5_HUMAN FYVE, RhoGEF and PH domain-contain... | 312 | 0.001 | 47.4 | 20 | 41 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0031267; F:small GTPase binding; ISS:UniProtKB. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; ISS:UniProtKB.::GO:0043088; P:regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB. | 145 | Q6DT37 | 1551 | MRCKG_HUMAN Serine/threonine-protein kinase M... | 355 | 0.001 | 47 | 23 | 38 | GO:0031252; C:cell leading edge; IDA:UniProtKB.::GO:0005813; C:centrosome; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 146 | Q63406 | 1149 | MCF2L_RAT Guanine nucleotide exchange factor ... | 207 | 0.001 | 47 | 27 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 147 | P91621 | 2072 | SIF1_DROME Protein still life, isoform SIF ty... | 208 | 0.001 | 47 | 24 | 42 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase. | 148 | Q9ES28 | 862 | ARHG7_MOUSE Rho guanine nucleotide exchange f... | 181 | 0.002 | 46.6 | 23 | 43 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 149 | P91620 | 2061 | SIF2_DROME Protein still life, isoforms C/SIF... | 210 | 0.002 | 46.6 | 24 | 42 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005057; F:receptor signaling protein activity; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050770; P:regulation of axonogenesis; IGI:FlyBase.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0050803; P:regulation of synapse structure and activity; TAS:FlyBase. | 150 | A6QNS3 | 859 | ABR_BOVIN Active breakpoint cluster region-re... | 197 | 0.002 | 46.2 | 23 | 45 | | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 151 | Q9Y5S2 | 1711 | MRCKB_HUMAN Serine/threonine-protein kinase M... | 351 | 0.003 | 46.2 | 20 | 41 | GO:0042641; C:actomyosin; IDA:UniProtKB.::GO:0031252; C:cell leading edge; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0031032; P:actomyosin structure organization; IMP:UniProtKB.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007163; P:establishment or maintenance of cell polarity; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. |
