| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | P65615 | 306 | PYRB_NEIMA Aspartate carbamoyltransferase OS=... | 281 | 8e-18 | 84.7 | 31 | 47 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 422 | Q46DA6 | 308 | PYRB_METBF Aspartate carbamoyltransferase OS=... | 264 | 2e-17 | 83.6 | 30 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 423 | A0KQG0 | 306 | PYRB_AERHH Aspartate carbamoyltransferase OS=... | 282 | 7e-17 | 82 | 31 | 47 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 424 | A4SHP8 | 306 | PYRB_AERS4 Aspartate carbamoyltransferase OS=... | 282 | 1e-16 | 81.3 | 31 | 47 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 425 | Q8THL2 | 308 | PYRB_METAC Aspartate carbamoyltransferase OS=... | 264 | 1e-16 | 80.9 | 30 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 426 | C4LBX2 | 307 | PYRB_TOLAT Aspartate carbamoyltransferase OS=... | 284 | 2e-16 | 80.5 | 33 | 48 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 427 | Q8PXK5 | 309 | PYRB_METMA Aspartate carbamoyltransferase OS=... | 264 | 2e-16 | 80.5 | 29 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 428 | Q7P145 | 302 | PYRB_CHRVO Aspartate carbamoyltransferase OS=... | 282 | 0.000000000000001 | 78.6 | 30 | 48 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 429 | Q2FN12 | 298 | PYRB_METHJ Aspartate carbamoyltransferase OS=... | 281 | 0.000000000000002 | 77.8 | 27 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 430 | P27708 | 2225 | PYR1_HUMAN CAD protein OS=Homo sapiens (Human... | 275 | 0.000000000000003 | 79.7 | 28 | 44 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; ISS:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL.::GO:0043195; C:terminal button; ISS:BHF-UCL. | | | | | | | | | | GO:0070335; F:aspartate binding; ISS:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; ISS:BHF-UCL.::GO:0005524; F:ATP binding; ISS:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; ISS:BHF-UCL.::GO:0004151; F:dihydroorotase activity; ISS:BHF-UCL.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0042802; F:identical protein binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; ISS:BHF-UCL. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; ISS:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0017144; P:drug metabolic process; ISS:BHF-UCL.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; ISS:BHF-UCL.::GO:0046777; P:protein autophosphorylation; ISS:BHF-UCL.::GO:0046134; P:pyrimidine nucleoside biosynthetic process; TAS:Reactome.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 431 | B8GF03 | 298 | PYRB_METPE Aspartate carbamoyltransferase OS=... | 280 | 0.000000000000004 | 77 | 27 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 432 | Q8TVB2 | 309 | PYRB_METKA Aspartate carbamoyltransferase OS=... | 279 | 0.000000000000004 | 77 | 28 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 433 | B0TST3 | 310 | PYRB2_SHEHH Aspartate carbamoyltransferase 2 ... | 283 | 0.00000000000001 | 75.9 | 29 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 434 | A8MIU1 | 331 | PYRB_ALKOO Aspartate carbamoyltransferase OS=... | 288 | 0.00000000000004 | 74.7 | 28 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 435 | P08955 | 2225 | PYR1_MESAU CAD protein OS=Mesocricetus auratu... | 275 | 0.00000000000006 | 75.5 | 28 | 43 | GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0005739; C:mitochondrion; IDA:BHF-UCL.::GO:0016363; C:nuclear matrix; IDA:BHF-UCL. | | | | | | | | | | GO:0070335; F:aspartate binding; IDA:BHF-UCL.::GO:0004070; F:aspartate carbamoyltransferase activity; IDA:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IDA:BHF-UCL.::GO:0004151; F:dihydroorotase activity; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IDA:BHF-UCL.::GO:0002134; F:UTP binding; IDA:MGI. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IDA:BHF-UCL.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:BHF-UCL.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 436 | A0B8L1 | 304 | PYRB_METTP Aspartate carbamoyltransferase OS=... | 243 | 0.00000000000007 | 73.6 | 28 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 437 | C1D9A7 | 308 | PYRB_LARHH Aspartate carbamoyltransferase OS=... | 285 | 0.00000000000007 | 73.6 | 29 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 438 | A9KNJ3 | 307 | PYRB_CLOPH Aspartate carbamoyltransferase OS=... | 280 | 0.00000000000007 | 73.6 | 28 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 439 | P96174 | 310 | PYRB_VIBS2 Aspartate carbamoyltransferase cat... | 284 | 0.0000000000001 | 73.2 | 31 | 47 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 440 | Q91437 | 2242 | PYR1_SQUAC CAD protein OS=Squalus acanthias (... | 275 | 0.0000000000002 | 74.3 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004088; F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity; IEA:EC.::GO:0004151; F:dihydroorotase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0070409; P:carbamoyl phosphate biosynthetic process; IEA:InterPro.::GO:0006543; P:glutamine catabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 441 | A9A2Q5 | 309 | PYRB_NITMS Aspartate carbamoyltransferase OS=... | 278 | 0.0000000000002 | 72.4 | 29 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 442 | B6YXW4 | 310 | PYRB_THEON Aspartate carbamoyltransferase OS=... | 262 | 0.0000000000003 | 72 | 28 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 443 | C5A2H1 | 308 | PYRB_THEGJ Aspartate carbamoyltransferase OS=... | 262 | 0.0000000000006 | 70.9 | 28 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 444 | A3CW66 | 298 | PYRB_METMJ Aspartate carbamoyltransferase OS=... | 269 | 0.0000000000006 | 70.9 | 27 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 445 | B2TNG3 | 307 | PYRB_CLOBB Aspartate carbamoyltransferase OS=... | 272 | 0.0000000000007 | 70.9 | 29 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 446 | P77918 | 308 | PYRB_PYRAB Aspartate carbamoyltransferase OS=... | 274 | 0.0000000000007 | 70.9 | 27 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:HAMAP. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:HAMAP. | 447 | B2UW93 | 307 | PYRB_CLOBA Aspartate carbamoyltransferase OS=... | 272 | 0.0000000000008 | 70.5 | 29 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 448 | O58451 | 308 | PYRB_PYRHO Aspartate carbamoyltransferase OS=... | 274 | 0.000000000001 | 70.5 | 26 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 449 | Q9HHN4 | 310 | PYRB_HALSA Aspartate carbamoyltransferase OS=... | 286 | 0.000000000001 | 70.1 | 26 | 44 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 450 | B0TPF3 | 310 | PYRB3_SHEHH Aspartate carbamoyltransferase 3 ... | 283 | 0.000000000002 | 69.7 | 28 | 46 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. | 451 | P19910 | 306 | PYRB_SERMA Aspartate carbamoyltransferase cat... | 284 | 0.000000000002 | 69.3 | 29 | 45 | | | | | | | | | | | GO:0016597; F:amino acid binding; IEA:InterPro.::GO:0004070; F:aspartate carbamoyltransferase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0006520; P:cellular amino acid metabolic process; IEA:InterPro.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:UniProtKB-KW. |
