| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O94323 | 485 | YGK5_SCHPO Uncharacterized pyrophosphatase/ph... | 464 | 9e-119 | 373 | 43 | 60 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047429; F:nucleoside-triphosphate diphosphatase activity; ISS:PomBase.::GO:0004551; F:nucleotide diphosphatase activity; ISS:PomBase. | | | | | | | | | | GO:0009141; P:nucleoside triphosphate metabolic process; ISS:PomBase. | 2 | Q924C3 | 906 | ENPP1_RAT Ectonucleotide pyrophosphatase/phos... | 424 | 2e-74 | 265 | 36 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0006955; P:immune response; IEA:InterPro. | 3 | P22413 | 925 | ENPP1_HUMAN Ectonucleotide pyrophosphatase/ph... | 402 | 3e-74 | 264 | 36 | 55 | GO:0016323; C:basolateral plasma membrane; NAS:BHF-UCL.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; TAS:ProtInc. | | | | | | | | | | GO:0050656; F:3'-phosphoadenosine 5'-phosphosulfate binding; IC:BHF-UCL.::GO:0005524; F:ATP binding; IDA:BHF-UCL.::GO:0005158; F:insulin receptor binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:BHF-UCL.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0050427; P:3'-phosphoadenosine 5'-phosphosulfate metabolic process; IDA:BHF-UCL.::GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0030643; P:cellular phosphate ion homeostasis; IDA:BHF-UCL.::GO:0032869; P:cellular response to insulin stimulus; IDA:BHF-UCL.::GO:0006091; P:generation of precursor metabolites and energy; IDA:BHF-UCL.::GO:0006955; P:immune response; IEA:InterPro.::GO:0030505; P:inorganic diphosphate transport; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0045599; P:negative regulation of fat cell differentiation; IDA:BHF-UCL.::GO:0046325; P:negative regulation of glucose import; IDA:BHF-UCL.::GO:0045719; P:negative regulation of glycogen biosynthetic process; IDA:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IDA:BHF-UCL.::GO:0031953; P:negative regulation of protein autophosphorylation; IDA:BHF-UCL.::GO:0009143; P:nucleoside triphosphate catabolic process; IDA:BHF-UCL.::GO:0006796; P:phosphate-containing compound metabolic process; IDA:BHF-UCL.::GO:0030500; P:regulation of bone mineralization; IC:BHF-UCL.::GO:0006771; P:riboflavin metabolic process; TAS:Reactome.::GO:0030730; P:sequestering of triglyceride; IDA:BHF-UCL. | 4 | P15396 | 874 | ENPP3_BOVIN Ectonucleotide pyrophosphatase/ph... | 400 | 3e-74 | 263 | 35 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006955; P:immune response; IEA:InterPro. | 5 | P06802 | 906 | ENPP1_MOUSE Ectonucleotide pyrophosphatase/ph... | 438 | 1e-73 | 263 | 35 | 54 | GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0031214; P:biomineral tissue development; IEA:UniProtKB-KW.::GO:0046849; P:bone remodeling; IMP:MGI.::GO:0006955; P:immune response; IEA:InterPro.::GO:0045599; P:negative regulation of fat cell differentiation; IMP:BHF-UCL.::GO:0030279; P:negative regulation of ossification; IMP:MGI. | 6 | P25353 | 742 | NPP1_YEAST Ectonucleotide pyrophosphatase/pho... | 516 | 4e-70 | 250 | 33 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0017111; F:nucleoside-triphosphatase activity; IMP:SGD.::GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:SGD.::GO:0004528; F:phosphodiesterase I activity; ISS:SGD. | | | | | | | | | | GO:0016036; P:cellular response to phosphate starvation; IEP:SGD.::GO:0009141; P:nucleoside triphosphate metabolic process; IMP:SGD.::GO:0006796; P:phosphate-containing compound metabolic process; ISS:SGD. | 7 | O14638 | 875 | ENPP3_HUMAN Ectonucleotide pyrophosphatase/ph... | 400 | 7e-70 | 251 | 35 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IDA:BHF-UCL.::GO:0004528; F:phosphodiesterase I activity; TAS:ProtInc.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006955; P:immune response; IEA:InterPro.::GO:0009143; P:nucleoside triphosphate catabolic process; IDA:BHF-UCL.::GO:0006796; P:phosphate-containing compound metabolic process; IDA:BHF-UCL. | 8 | Q6DYE8 | 874 | ENPP3_MOUSE Ectonucleotide pyrophosphatase/ph... | 462 | 1e-69 | 250 | 32 | 51 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006955; P:immune response; IEA:InterPro. | 9 | P97675 | 875 | ENPP3_RAT Ectonucleotide pyrophosphatase/phos... | 400 | 2e-69 | 250 | 34 | 54 | GO:0009986; C:cell surface; TAS:RGD.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; TAS:RGD.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006955; P:immune response; IEA:InterPro.::GO:0051150; P:regulation of smooth muscle cell differentiation; NAS:RGD. | 10 | Q5R5M5 | 873 | ENPP3_PONAB Ectonucleotide pyrophosphatase/ph... | 400 | 1e-68 | 248 | 35 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004528; F:phosphodiesterase I activity; IEA:EC.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro. | | | | | | | | | | GO:0006955; P:immune response; IEA:InterPro. | 11 | Q6AX80 | 452 | ENPP4_XENLA Ectonucleotide pyrophosphatase/ph... | 433 | 7e-66 | 231 | 33 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 12 | Q8BTJ4 | 456 | ENPP4_MOUSE Ectonucleotide pyrophosphatase/ph... | 408 | 1e-64 | 228 | 34 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 13 | Q6DDP3 | 441 | ENPP6_XENLA Ectonucleotide pyrophosphatase/ph... | 404 | 1e-63 | 224 | 34 | 55 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 14 | Q566N0 | 459 | ENPP4_DANRE Ectonucleotide pyrophosphatase/ph... | 431 | 2e-63 | 224 | 32 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q9R1E6 | 862 | ENPP2_MOUSE Ectonucleotide pyrophosphatase/ph... | 401 | 3e-63 | 231 | 34 | 54 | GO:0005615; C:extracellular space; IDA:UniProtKB. | | | | | | | | | | GO:0047391; F:alkylglycerophosphoethanolamine phosphodiesterase activity; IEA:EC.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0004622; F:lysophospholipase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006955; P:immune response; IEA:InterPro.::GO:0034638; P:phosphatidylcholine catabolic process; IDA:UniProtKB. | 16 | B0BND0 | 440 | ENPP6_RAT Ectonucleotide pyrophosphatase/phos... | 399 | 8e-62 | 219 | 34 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 17 | Q0VA77 | 452 | ENPP4_XENTR Ectonucleotide pyrophosphatase/ph... | 434 | 9e-62 | 219 | 32 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 18 | Q64610 | 887 | ENPP2_RAT Ectonucleotide pyrophosphatase/phos... | 399 | 2e-61 | 226 | 34 | 52 | GO:0005615; C:extracellular space; IDA:UniProtKB. | | | | | | | | | | GO:0047391; F:alkylglycerophosphoethanolamine phosphodiesterase activity; IEA:EC.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0004622; F:lysophospholipase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:UniProtKB. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006955; P:immune response; IEA:InterPro.::GO:0034638; P:phosphatidylcholine catabolic process; IDA:UniProtKB. | 19 | Q5BKW7 | 438 | ENPP6_DANRE Ectonucleotide pyrophosphatase/ph... | 398 | 2e-61 | 218 | 32 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 20 | Q8BGN3 | 440 | ENPP6_MOUSE Ectonucleotide pyrophosphatase/ph... | 398 | 4e-61 | 218 | 33 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IDA:MGI. | | | | | | | | | | GO:0019695; P:choline metabolic process; IDA:MGI.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 21 | Q6UWR7 | 440 | ENPP6_HUMAN Ectonucleotide pyrophosphatase/ph... | 398 | 1e-60 | 216 | 33 | 54 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 22 | Q58D68 | 440 | ENPP6_BOVIN Ectonucleotide pyrophosphatase/ph... | 401 | 2e-60 | 216 | 33 | 53 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 23 | Q13822 | 863 | ENPP2_HUMAN Ectonucleotide pyrophosphatase/ph... | 399 | 2e-60 | 223 | 33 | 52 | GO:0005615; C:extracellular space; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047391; F:alkylglycerophosphoethanolamine phosphodiesterase activity; IEA:EC.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004622; F:lysophospholipase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0004551; F:nucleotide diphosphatase activity; TAS:ProtInc.::GO:0004528; F:phosphodiesterase I activity; TAS:ProtInc.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006928; P:cellular component movement; TAS:ProtInc.::GO:0006935; P:chemotaxis; NAS:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0006955; P:immune response; IEA:InterPro.::GO:0006796; P:phosphate-containing compound metabolic process; TAS:ProtInc.::GO:0034638; P:phosphatidylcholine catabolic process; IDA:UniProtKB.::GO:0030334; P:regulation of cell migration; IDA:UniProtKB. | 24 | A1A4K5 | 888 | ENPP2_BOVIN Ectonucleotide pyrophosphatase/ph... | 406 | 1e-59 | 221 | 33 | 51 | GO:0005615; C:extracellular space; ISS:UniProtKB. | | | | | | | | | | GO:0047391; F:alkylglycerophosphoethanolamine phosphodiesterase activity; IEA:EC.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004622; F:lysophospholipase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0030247; F:polysaccharide binding; IEA:InterPro.::GO:0005044; F:scavenger receptor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; ISS:UniProtKB. | | | | | | | | | | GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006955; P:immune response; IEA:InterPro.::GO:0034638; P:phosphatidylcholine catabolic process; ISS:UniProtKB. | 25 | Q9Y6X5 | 453 | ENPP4_HUMAN Ectonucleotide pyrophosphatase/ph... | 405 | 3e-59 | 213 | 33 | 51 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 26 | Q5RAC0 | 452 | ENPP4_PONAB Ectonucleotide pyrophosphatase/ph... | 405 | 3e-58 | 210 | 33 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 27 | A2VDP5 | 453 | ENPP4_BOVIN Ectonucleotide pyrophosphatase/ph... | 404 | 2e-56 | 204 | 32 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | Q9UJA9 | 477 | ENPP5_HUMAN Ectonucleotide pyrophosphatase/ph... | 424 | 3e-56 | 204 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 29 | Q9EQG7 | 477 | ENPP5_MOUSE Ectonucleotide pyrophosphatase/ph... | 392 | 4e-54 | 198 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | P84039 | 477 | ENPP5_RAT Ectonucleotide pyrophosphatase/phos... | 396 | 7e-53 | 195 | 31 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007154; P:cell communication; IDA:UniProtKB. | 31 | P39997 | 493 | NPP2_YEAST Ectonucleotide pyrophosphatase/pho... | 488 | 5e-52 | 193 | 32 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035529; F:NADH pyrophosphatase activity; IEA:EC.::GO:0017111; F:nucleoside-triphosphatase activity; IMP:SGD.::GO:0047429; F:nucleoside-triphosphate diphosphatase activity; IMP:SGD.::GO:0004528; F:phosphodiesterase I activity; ISS:SGD. | | | | | | | | | | GO:0009141; P:nucleoside triphosphate metabolic process; IMP:SGD. |
