| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
421 | Q8CH72 | 655 | TRI32_MOUSE E3 ubiquitin-protein ligase TRIM3... | 47 | 0.57 | 38.1 | 36 | 62 | GO:0005737; C:cytoplasm; ISS:BHF-UCL.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0017022; F:myosin binding; IPI:MGI.::GO:0043621; F:protein self-association; ISS:BHF-UCL.::GO:0003723; F:RNA binding; IDA:BHF-UCL.::GO:0031369; F:translation initiation factor binding; IPI:MGI.::GO:0043130; F:ubiquitin binding; ISS:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045444; P:fat cell differentiation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; IEP:BHF-UCL.::GO:0045787; P:positive regulation of cell cycle; ISS:BHF-UCL.::GO:0030307; P:positive regulation of cell growth; ISS:BHF-UCL.::GO:0030335; P:positive regulation of cell migration; ISS:BHF-UCL.::GO:0050769; P:positive regulation of neurogenesis; IDA:BHF-UCL.::GO:0045666; P:positive regulation of neuron differentiation; IDA:BHF-UCL.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0045732; P:positive regulation of protein catabolic process; IDA:BHF-UCL.::GO:0045862; P:positive regulation of proteolysis; ISS:BHF-UCL.::GO:0000209; P:protein polyubiquitination; ISS:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IDA:BHF-UCL.::GO:0009411; P:response to UV; IDA:BHF-UCL. | 422 | P09309 | 467 | IE61_VZVD E3 ubiquitin-protein ligase IE61 OS... | 84 | 0.63 | 38.1 | 29 | 39 | | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 423 | Q969Q1 | 353 | TRI63_HUMAN E3 ubiquitin-protein ligase TRIM6... | 69 | 0.66 | 37.7 | 26 | 41 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005874; C:microtubule; NAS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004871; F:signal transducer activity; NAS:UniProtKB.::GO:0031432; F:titin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 424 | E7FAP1 | 630 | RN169_DANRE E3 ubiquitin-protein ligase RNF16... | 66 | 0.73 | 37.7 | 29 | 39 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 425 | Q9CK01 | 967 | RAPA_PASMU RNA polymerase-associated protein ... | 106 | 0.74 | 38.1 | 26 | 43 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 426 | Q8IYW5 | 571 | RN168_HUMAN E3 ubiquitin-protein ligase RNF16... | 124 | 0.77 | 37.7 | 26 | 39 | GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; IDA:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB. | 427 | Q810I1 | 483 | TRI50_RAT E3 ubiquitin-protein ligase TRIM50 ... | 64 | 0.81 | 37.7 | 27 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 428 | Q7YRV4 | 469 | RO52_BOVIN E3 ubiquitin-protein ligase TRIM21... | 61 | 0.84 | 37.7 | 34 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB. | 429 | Q0I5G1 | 966 | RAPA_HAES1 RNA polymerase-associated protein ... | 140 | 0.86 | 37.7 | 25 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 430 | Q95153 | 1878 | BRCA1_CANFA Breast cancer type 1 susceptibili... | 102 | 0.86 | 37.7 | 25 | 47 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0045717; P:negative regulation of fatty acid biosynthetic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB. | 431 | Q9R1A8 | 733 | RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2... | 64 | 0.88 | 37.7 | 28 | 48 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 432 | Q5PQN2 | 450 | BFAR_RAT Bifunctional apoptosis regulator OS=... | 69 | 0.95 | 37.4 | 29 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 433 | Q8R079 | 450 | BFAR_MOUSE Bifunctional apoptosis regulator O... | 69 | 0.95 | 37.4 | 29 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 434 | Q8NHY2 | 731 | RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2... | 64 | 0.96 | 37.7 | 28 | 48 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome. | 435 | B0BLU1 | 535 | RN168_XENTR E3 ubiquitin-protein ligase RNF16... | 105 | 0.98 | 37.4 | 24 | 37 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB. | 436 | Q8BZT2 | 735 | SH3R2_MOUSE Putative E3 ubiquitin-protein lig... | 58 | 1 | 37.4 | 26 | 41 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 437 | Q498M5 | 735 | SH3R2_RAT Putative E3 ubiquitin-protein ligas... | 30 | 1 | 37.4 | 37 | 57 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 438 | O94972 | 964 | TRI37_HUMAN E3 ubiquitin-protein ligase TRIM3... | 79 | 1 | 37.7 | 27 | 41 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 439 | Q6PJ69 | 517 | TRI65_HUMAN Tripartite motif-containing prote... | 30 | 1.1 | 37.4 | 47 | 53 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 440 | Q6INB3 | 246 | RN182_XENLA E3 ubiquitin-protein ligase RNF18... | 66 | 1.1 | 36.6 | 30 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 441 | Q8CEF8 | 211 | RN222_MOUSE RING finger protein 222 OS=Mus mu... | 67 | 1.1 | 36.6 | 30 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 442 | Q8BFW4 | 522 | TRI65_MOUSE Tripartite motif-containing prote... | 66 | 1.1 | 37.4 | 30 | 45 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 443 | B8B5U8 | 321 | BAHL2_ORYSI Probable E3 ubiquitin-protein lig... | 74 | 1.1 | 37 | 28 | 45 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 444 | Q7XI73 | 321 | BAHL2_ORYSJ Probable E3 ubiquitin-protein lig... | 74 | 1.1 | 37 | 28 | 45 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 445 | Q865W2 | 486 | TRI50_PIG E3 ubiquitin-protein ligase TRIM50 ... | 64 | 1.2 | 37 | 27 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 446 | Q9NZS9 | 450 | BFAR_HUMAN Bifunctional apoptosis regulator O... | 59 | 1.2 | 37 | 31 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; IDA:MGI. | | | | | | | | | | GO:0005198; F:structural molecule activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:MGI.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW. | 447 | Q87XS2 | 948 | RAPA_PSESM RNA polymerase-associated protein ... | 119 | 1.2 | 37.4 | 24 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 448 | Q5C8T6 | 493 | TRIM5_GORGO Tripartite motif-containing prote... | 61 | 1.2 | 37 | 33 | 46 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 449 | Q8TEC5 | 729 | SH3R2_HUMAN Putative E3 ubiquitin-protein lig... | 63 | 1.2 | 37.4 | 25 | 41 | | | | | | | | | | | GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; IDA:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 450 | Q9FKD5 | 276 | SINL9_ARATH Putative E3 ubiquitin-protein lig... | 73 | 1.3 | 36.6 | 29 | 44 | GO:0005634; C:nucleus; IEA:InterPro. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. | 451 | Q2TBT8 | 240 | RN151_BOVIN RING finger protein 151 OS=Bos ta... | 77 | 1.3 | 36.2 | 22 | 43 | | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | |
