| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
901 | Q5S007 | 2527 | LRRK2_HUMAN Leucine-rich repeat serine/threon... | 164 | 0.0002 | 45.1 | 25 | 41 | GO:0032473; C:external side of mitochondrial outer membrane; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0034211; F:GTP-dependent protein kinase activity; IMP:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0004708; F:MAP kinase kinase activity; IDA:BHF-UCL.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0017048; F:Rho GTPase binding; IPI:BHF-UCL.::GO:0015631; F:tubulin binding; IDA:BHF-UCL. | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; IDA:BHF-UCL.::GO:0008340; P:determination of adult lifespan; IMP:BHF-UCL.::GO:0035640; P:exploration behavior; IMP:BHF-UCL.::GO:0048312; P:intracellular distribution of mitochondria; IMP:BHF-UCL.::GO:2000173; P:negative regulation of branching morphogenesis of a nerve; IMP:BHF-UCL.::GO:0061002; P:negative regulation of dendritic spine morphogenesis; IMP:BHF-UCL.::GO:0007406; P:negative regulation of neuroblast proliferation; IMP:BHF-UCL.::GO:0014043; P:negative regulation of neuron maturation; IMP:BHF-UCL.::GO:0007528; P:neuromuscular junction development; IMP:BHF-UCL.::GO:0070997; P:neuron death; IMP:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:BHF-UCL.::GO:0010508; P:positive regulation of autophagy; ISS:BHF-UCL.::GO:0060161; P:positive regulation of dopamine receptor signaling pathway; IMP:BHF-UCL.::GO:0043068; P:positive regulation of programmed cell death; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:BHF-UCL.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0035564; P:regulation of kidney size; ISS:BHF-UCL.::GO:0040012; P:regulation of locomotion; IMP:BHF-UCL.::GO:0042391; P:regulation of membrane potential; IMP:BHF-UCL.::GO:0006979; P:response to oxidative stress; IMP:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IMP:BHF-UCL. | 902 | O95661 | 229 | DIRA3_HUMAN GTP-binding protein Di-Ras3 OS=Ho... | 172 | 0.0003 | 43.9 | 23 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc. | | | | | | | | | | GO:0000079; P:regulation of cyclin-dependent protein kinase activity; TAS:ProtInc.::GO:0006349; P:regulation of gene expression by genetic imprinting; TAS:ProtInc.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 903 | Q1ZXB9 | 148 | RABK3_DICDI Ras-related protein RabK3 OS=Dict... | 112 | 0.0004 | 42.7 | 29 | 46 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 904 | Q7ZYF1 | 273 | DJ27A_XENLA DnaJ homolog subfamily C member 2... | 132 | 0.0004 | 43.5 | 20 | 45 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro. | | | | | | | | | | GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 905 | Q9SJZ5 | 176 | RAA4E_ARATH Putative Ras-related protein RABA... | 179 | 0.0005 | 42.7 | 26 | 41 | | | | | | | | | | | GO:0005525; F:GTP binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 906 | P61208 | 192 | ARL4C_MOUSE ADP-ribosylation factor-like prot... | 125 | 0.0005 | 42.7 | 31 | 46 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0032456; P:endocytic recycling; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 907 | P56559 | 192 | ARL4C_HUMAN ADP-ribosylation factor-like prot... | 125 | 0.0005 | 42.7 | 31 | 46 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc. | | | | | | | | | | GO:0032456; P:endocytic recycling; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 908 | Q8MVR1 | 2631 | GBPC_DICDI Cyclic GMP-binding protein C OS=Di... | 98 | 0.0006 | 43.9 | 32 | 52 | GO:0005737; C:cytoplasm; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IDA:dictyBase.::GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0005543; F:phospholipid binding; IDA:dictyBase.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005088; F:Ras guanyl-nucleotide exchange factor activity; IDA:dictyBase. | | | | | | | | | | GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0019934; P:cGMP-mediated signaling; IDA:dictyBase.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:dictyBase.::GO:0051272; P:positive regulation of cellular component movement; TAS:dictyBase.::GO:0045860; P:positive regulation of protein kinase activity; IMP:dictyBase.::GO:0046579; P:positive regulation of Ras protein signal transduction; IDA:dictyBase.::GO:0050920; P:regulation of chemotaxis; IMP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 909 | Q6DGN0 | 205 | RERGL_DANRE Ras-related and estrogen-regulate... | 126 | 0.0007 | 42.7 | 27 | 41 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 910 | Q1ZXD6 | 2800 | ROCO5_DICDI Probable serine/threonine-protein... | 71 | 0.0009 | 43.1 | 35 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. | 911 | P39722 | 662 | GEM1_YEAST Mitochondrial Rho GTPase 1 OS=Sacc... | 127 | 0.28 | 35.4 | 25 | 44 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD. | | | | | | | | | | GO:0005509; F:calcium ion binding; IDA:SGD.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0000001; P:mitochondrion inheritance; IMP:SGD.::GO:0010821; P:regulation of mitochondrion organization; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 912 | P24498 | 209 | RAS_GEOCY Ras-like protein OS=Geodia cydonium... | 142 | 0.001 | 41.6 | 28 | 42 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 913 | Q54WS5 | 2147 | ROCO6_DICDI Probable serine/threonine-protein... | 74 | 0.003 | 41.6 | 30 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 914 | O59781 | 630 | GEM1_SCHPO Mitochondrial Rho GTPase 1 OS=Schi... | 121 | 4.5 | 31.6 | 28 | 39 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007005; P:mitochondrion organization; ISS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase. | 915 | P40994 | 183 | ARF3_YEAST ADP-ribosylation factor 3 OS=Sacch... | 126 | 0.01 | 38.9 | 26 | 41 | GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0051017; P:actin filament bundle assembly; IGI:SGD.::GO:0000282; P:cellular bud site selection; IMP:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 916 | Q6FIR8 | 649 | GEM1_CANGA Mitochondrial Rho GTPase 1 OS=NRRL... | 181 | 0.56 | 34.7 | 24 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 917 | Q6CY37 | 659 | GEM1_KLULA Mitochondrial Rho GTPase 1 OS=1267... | 122 | 0.021 | 38.9 | 28 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 918 | Q47RV1 | 955 | IF2_THEFY Translation initiation factor IF-2 ... | 119 | 0.023 | 38.9 | 33 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 919 | Q46HI4 | 464 | MNME_PROMT tRNA modification GTPase MnmE OS=P... | 129 | 0.028 | 38.5 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006400; P:tRNA modification; IEA:InterPro. | 920 | B2J955 | 1056 | IF2_NOSP7 Translation initiation factor IF-2 ... | 118 | 0.033 | 38.5 | 31 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 921 | Q54HK2 | 190 | ARFF_DICDI ADP-ribosylation factor F OS=Dicty... | 124 | 0.034 | 37.7 | 23 | 44 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 922 | P34212 | 178 | ARL5_CAEEL ADP-ribosylation factor-like prote... | 138 | 0.037 | 37.4 | 25 | 39 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0000226; P:microtubule cytoskeleton organization; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 923 | B7J1B2 | 464 | MNME_BORBZ tRNA modification GTPase MnmE OS=B... | 141 | 0.041 | 37.7 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006400; P:tRNA modification; IEA:InterPro. | 924 | P53364 | 464 | MNME_BORBU tRNA modification GTPase MnmE OS=4... | 141 | 0.041 | 37.7 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006400; P:tRNA modification; IEA:InterPro. | 925 | Q7RZA2 | 629 | GEM1_NEUCR Mitochondrial Rho GTPase 1 OS=1257... | 181 | 0.041 | 38.1 | 25 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 926 | Q1IIT3 | 1011 | IF2_KORVE Translation initiation factor IF-2 ... | 111 | 0.043 | 38.1 | 29 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 927 | Q9BU20 | 258 | RSG1_HUMAN REM2- and Rab-like small GTPase 1 ... | 125 | 0.046 | 37.4 | 25 | 40 | GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0005932; C:microtubule basal body; ISS:UniProtKB. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0034613; P:cellular protein localization; ISS:UniProtKB.::GO:0042384; P:cilium assembly; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0031338; P:regulation of vesicle fusion; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 928 | Q4I2W2 | 627 | GEM1_GIBZE Mitochondrial Rho GTPase 1 OS=(Whe... | 182 | 0.055 | 37.7 | 25 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro. | | | | | | | | | | GO:0019725; P:cellular homeostasis; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 929 | B1XI09 | 979 | IF2_SYNP2 Translation initiation factor IF-2 ... | 118 | 0.071 | 37.4 | 31 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 930 | P39110 | 191 | CIN4_YEAST GTP-binding protein CIN4 OS=Saccha... | 188 | 0.071 | 36.6 | 21 | 42 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0005525; F:GTP binding; ISS:SGD. | | | | | | | | | | GO:0006457; P:protein folding; IGI:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 931 | Q8BXK8 | 857 | AGAP1_MOUSE Arf-GAP with GTPase, ANK repeat a... | 186 | 0.084 | 37 | 23 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. |
