| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | P10830 | 736 | KPCE_RABIT Protein kinase C epsilon type OS=O... | 379 | 7e-42 | 165 | 30 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; ISS:UniProtKB. | 182 | Q5PU49 | 674 | KPCD_CANFA Protein kinase C delta type OS=Can... | 413 | 8e-42 | 164 | 27 | 45 | GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB. | 183 | P16054 | 737 | KPCE_MOUSE Protein kinase C epsilon type OS=M... | 378 | 9e-42 | 165 | 30 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; IPI:UniProtKB.::GO:0003785; F:actin monomer binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:MGI.::GO:0035276; F:ethanol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030546; F:receptor activator activity; IDA:MGI. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071361; P:cellular response to ethanol; IGI:MGI.::GO:0071456; P:cellular response to hypoxia; IDA:MGI.::GO:0007635; P:chemosensory behavior; TAS:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0035641; P:locomotory exploration behavior; IGI:MGI.::GO:0002281; P:macrophage activation involved in immune response; IMP:MGI.::GO:0030838; P:positive regulation of actin filament polymerization; IDA:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010811; P:positive regulation of cell-substrate adhesion; IMP:MGI.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0032024; P:positive regulation of insulin secretion; IMP:MGI.::GO:0050996; P:positive regulation of lipid catabolic process; IMP:MGI.::GO:0043410; P:positive regulation of MAPK cascade; IDA:MGI.::GO:0070257; P:positive regulation of mucus secretion; IMP:MGI.::GO:0032230; P:positive regulation of synaptic transmission, GABAergic; IMP:MGI.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0061178; P:regulation of insulin secretion involved in cellular response to glucose stimulus; IMP:MGI.::GO:0050730; P:regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:MGI.::GO:0043278; P:response to morphine; IMP:MGI.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; IMP:UniProtKB. | 184 | Q6PFQ0 | 740 | KS6A6_DANRE Ribosomal protein S6 kinase alpha... | 283 | 0.00000000009 | 68.9 | 23 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 185 | Q9WTQ0 | 707 | KPCT_RAT Protein kinase C theta type OS=Rattu... | 359 | 1e-41 | 164 | 29 | 49 | GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031594; C:neuromuscular junction; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0042383; C:sarcolemma; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0051491; P:positive regulation of filopodium assembly; IMP:RGD.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0042346; P:positive regulation of NF-kappaB import into nucleus; IMP:RGD.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:RGD.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0010389; P:regulation of G2/M transition of mitotic cell cycle; IMP:RGD.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0019229; P:regulation of vasoconstriction; IEP:RGD.::GO:0045730; P:respiratory burst; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0042246; P:tissue regeneration; IEP:RGD. | 186 | O43930 | 277 | PRKY_HUMAN Serine/threonine-protein kinase PR... | 246 | 2e-41 | 156 | 33 | 53 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | | 187 | F1M7Y5 | 596 | KPCI_RAT Protein kinase C iota type OS=Rattus... | 351 | 2e-41 | 162 | 30 | 47 | GO:0031252; C:cell leading edge; IDA:RGD.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0004697; F:protein kinase C activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; IMP:RGD.::GO:0034613; P:cellular protein localization; IMP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IMP:RGD.::GO:0048194; P:Golgi vesicle budding; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0070555; P:response to interleukin-1; IMP:RGD. | 188 | Q62074 | 595 | KPCI_MOUSE Protein kinase C iota type OS=Mus ... | 351 | 2e-41 | 162 | 30 | 47 | GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0043220; C:Schmidt-Lanterman incisure; IDA:BHF-UCL. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007015; P:actin filament organization; IMP:MGI.::GO:0045216; P:cell-cell junction organization; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IMP:BHF-UCL.::GO:0035089; P:establishment of apical/basal cell polarity; IMP:MGI.::GO:0042462; P:eye photoreceptor cell development; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 189 | Q5R4K9 | 596 | KPCI_PONAB Protein kinase C iota type OS=Pong... | 351 | 2e-41 | 162 | 30 | 47 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0060252; P:positive regulation of glial cell proliferation; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB. | 190 | P41743 | 596 | KPCI_HUMAN Protein kinase C iota type OS=Homo... | 351 | 2e-41 | 162 | 30 | 47 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000133; C:polarisome; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0032869; P:cellular response to insulin stimulus; ISS:BHF-UCL.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; TAS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0043524; P:negative regulation of neuron apoptotic process; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:2000353; P:positive regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0060252; P:positive regulation of glial cell proliferation; IMP:UniProtKB.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0010976; P:positive regulation of neuron projection development; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0006612; P:protein targeting to membrane; NAS:UniProtKB.::GO:0046903; P:secretion; NAS:UniProtKB.::GO:0070830; P:tight junction assembly; TAS:Reactome. | 191 | Q98TY9 | 481 | AKT1_XENLA RAC-alpha serine/threonine-protein... | 351 | 3e-41 | 160 | 29 | 48 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0015758; P:glucose transport; ISS:UniProtKB.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0045768; P:positive regulation of anti-apoptosis; ISS:UniProtKB.::GO:0010975; P:regulation of neuron projection development; ISS:UniProtKB. | 192 | Q13237 | 762 | KGP2_HUMAN cGMP-dependent protein kinase 2 OS... | 349 | 4e-41 | 163 | 31 | 50 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 193 | Q6IP76 | 485 | AKT2B_XENLA RAC-beta serine/threonine-protein... | 375 | 4e-41 | 160 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 194 | Q05655 | 676 | KPCD_HUMAN Protein kinase C delta type OS=Hom... | 423 | 7e-41 | 162 | 26 | 43 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; TAS:BHF-UCL.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB. | | | | | | | | | | GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0090398; P:cellular senescence; IMP:BHF-UCL.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; IMP:UniProtKB.::GO:0050728; P:negative regulation of inflammatory response; IC:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:BHF-UCL.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; ISS:BHF-UCL.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0032091; P:negative regulation of protein binding; TAS:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0042119; P:neutrophil activation; IDA:UniProtKB.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:2000304; P:positive regulation of ceramide biosynthetic process; IMP:BHF-UCL.::GO:2000753; P:positive regulation of glucosylceramide catabolic process; IMP:BHF-UCL.::GO:1900163; P:positive regulation of phospholipid scramblase activity; IMP:UniProtKB.::GO:0035307; P:positive regulation of protein dephosphorylation; IMP:BHF-UCL.::GO:2001022; P:positive regulation of response to DNA damage stimulus; IMP:UniProtKB.::GO:2000755; P:positive regulation of sphingomyelin catabolic process; IMP:BHF-UCL.::GO:0032930; P:positive regulation of superoxide anion generation; IMP:UniProtKB.::GO:0050821; P:protein stabilization; NAS:UniProtKB.::GO:0010469; P:regulation of receptor activity; TAS:BHF-UCL.::GO:0023021; P:termination of signal transduction; IMP:BHF-UCL. | 195 | P09215 | 673 | KPCD_RAT Protein kinase C delta type OS=Rattu... | 421 | 8e-41 | 161 | 27 | 45 | GO:0005829; C:cytosol; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004699; F:calcium-independent protein kinase C activity; IDA:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0070976; F:TIR domain binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007568; P:aging; IEP:RGD.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0015810; P:aspartate transport; IMP:RGD.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042149; P:cellular response to glucose starvation; IEP:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0032963; P:collagen metabolic process; IMP:RGD.::GO:0006917; P:induction of apoptosis; IDA:RGD.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0030837; P:negative regulation of actin filament polymerization; ISS:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; ISS:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0090331; P:negative regulation of platelet aggregation; ISS:UniProtKB.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0043406; P:positive regulation of MAP kinase activity; IMP:RGD.::GO:0043410; P:positive regulation of MAPK cascade; IMP:RGD.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0042542; P:response to hydrogen peroxide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0009612; P:response to mechanical stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD. | 196 | Q8QZV4 | 488 | ST32C_MOUSE Serine/threonine-protein kinase 3... | 330 | 9e-41 | 159 | 31 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 197 | P47197 | 481 | AKT2_RAT RAC-beta serine/threonine-protein ki... | 358 | 1e-40 | 159 | 28 | 47 | GO:0005829; C:cytosol; IDA:RGD.::GO:0032593; C:insulin-responsive compartment; IDA:RGD.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IPI:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD. | | | | | | | | | | GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:RGD.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:RGD.::GO:0033119; P:negative regulation of RNA splicing; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0046326; P:positive regulation of glucose import; IMP:RGD.::GO:0045429; P:positive regulation of nitric oxide biosynthetic process; IMP:RGD.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IMP:RGD.::GO:0050927; P:positive regulation of positive chemotaxis; IDA:RGD.::GO:0009967; P:positive regulation of signal transduction; IMP:RGD.::GO:0010765; P:positive regulation of sodium ion transport; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0043491; P:protein kinase B signaling cascade; IMP:RGD.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0014850; P:response to muscle activity; IEP:RGD.::GO:0006970; P:response to osmotic stress; IEP:RGD. | 198 | P43057 | 1097 | KPC1_CANAX Protein kinase C-like 1 OS=Candida... | 365 | 1e-40 | 163 | 29 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 199 | Q02111 | 707 | KPCT_MOUSE Protein kinase C theta type OS=Mus... | 351 | 2e-40 | 161 | 28 | 48 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001772; C:immunological synapse; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004697; F:protein kinase C activity; IDA:MGI. | | | | | | | | | | GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006509; P:membrane protein ectodomain proteolysis; IDA:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; ISS:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; ISS:UniProtKB.::GO:0032740; P:positive regulation of interleukin-17 production; IMP:UniProtKB.::GO:0045086; P:positive regulation of interleukin-2 biosynthetic process; IMP:MGI.::GO:0032753; P:positive regulation of interleukin-4 production; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:2000318; P:positive regulation of T-helper 17 type immune response; IMP:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB. | 200 | P09216 | 737 | KPCE_RAT Protein kinase C epsilon type OS=Rat... | 379 | 2e-40 | 161 | 30 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:RGD.::GO:0000139; C:Golgi membrane; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:RGD. | | | | | | | | | | GO:0003785; F:actin monomer binding; ISS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:RGD.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0030838; P:positive regulation of actin filament polymerization; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0010634; P:positive regulation of epithelial cell migration; ISS:UniProtKB.::GO:0010763; P:positive regulation of fibroblast migration; ISS:UniProtKB.::GO:0090303; P:positive regulation of wound healing; ISS:UniProtKB.::GO:0035669; P:TRAM-dependent toll-like receptor 4 signaling pathway; ISS:UniProtKB. | 201 | P28867 | 674 | KPCD_MOUSE Protein kinase C delta type OS=Mus... | 421 | 2e-40 | 160 | 26 | 44 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043560; F:insulin receptor substrate binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0042100; P:B cell proliferation; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016064; P:immunoglobulin mediated immune response; IMP:MGI.::GO:0032613; P:interleukin-10 production; IMP:MGI.::GO:0032615; P:interleukin-12 production; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030837; P:negative regulation of actin filament polymerization; IMP:UniProtKB.::GO:0051490; P:negative regulation of filopodium assembly; IMP:UniProtKB.::GO:0034351; P:negative regulation of glial cell apoptotic process; ISS:UniProtKB.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:BHF-UCL.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.::GO:0090331; P:negative regulation of platelet aggregation; IMP:UniProtKB.::GO:0032930; P:positive regulation of superoxide anion generation; ISS:UniProtKB. | 202 | Q7ZX15 | 486 | AKT2A_XENLA RAC-beta serine/threonine-protein... | 369 | 2e-40 | 157 | 28 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 203 | Q64595 | 762 | KGP2_RAT cGMP-dependent protein kinase 2 OS=R... | 343 | 3e-40 | 161 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 204 | O94324 | 1032 | PPK31_SCHPO Serine/threonine-protein kinase p... | 397 | 3e-40 | 162 | 30 | 46 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0007126; P:meiosis; IEA:UniProtKB-KW. | 205 | P38938 | 1338 | CEK1_SCHPO Serine/threonine-protein kinase ce... | 408 | 3e-40 | 162 | 29 | 47 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.::GO:0004871; F:signal transducer activity; IEA:InterPro. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase. | 206 | Q18846 | 772 | KS6A2_CAEEL Putative ribosomal protein S6 kin... | 251 | 0.000000002 | 64.7 | 24 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0002119; P:nematode larval development; IMP:WormBase. | 207 | Q12236 | 1081 | PKH2_YEAST Serine/threonine-protein kinase PK... | 338 | 3e-40 | 162 | 30 | 49 | GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD. | 208 | P31751 | 481 | AKT2_HUMAN RAC-beta serine/threonine-protein ... | 364 | 3e-40 | 157 | 28 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0045444; P:fat cell differentiation; TAS:UniProtKB.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0008286; P:insulin receptor signaling pathway; TAS:UniProtKB.::GO:0060644; P:mammary gland epithelial cell differentiation; TAS:UniProtKB.::GO:0010748; P:negative regulation of plasma membrane long-chain fatty acid transport; IMP:BHF-UCL.::GO:0032000; P:positive regulation of fatty acid beta-oxidation; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL.::GO:0045725; P:positive regulation of glycogen biosynthetic process; IMP:BHF-UCL.::GO:0071156; P:regulation of cell cycle arrest; TAS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 209 | Q54PK9 | 908 | PDPKB_DICDI 3-phosphoinositide-dependent prot... | 327 | 4e-40 | 161 | 28 | 48 | | | | | | | | | | | GO:0004676; F:3-phosphoinositide-dependent protein kinase activity; ISS:dictyBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | | 210 | Q61410 | 762 | KGP2_MOUSE cGMP-dependent protein kinase 2 OS... | 343 | 5e-40 | 160 | 31 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030553; F:cGMP binding; IEA:UniProtKB-KW.::GO:0004692; F:cGMP-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 211 | Q60823 | 481 | AKT2_MOUSE RAC-beta serine/threonine-protein ... | 358 | 6e-40 | 156 | 27 | 47 | GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008643; P:carbohydrate transport; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.::GO:0005978; P:glycogen biosynthetic process; IEA:UniProtKB-KW.::GO:0032287; P:peripheral nervous system myelin maintenance; IMP:MGI.::GO:2001275; P:positive regulation of glucose import in response to insulin stimulus; IGI:MGI.::GO:0072659; P:protein localization in plasma membrane; IGI:MGI.::GO:0046328; P:regulation of JNK cascade; IDA:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. |
