rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
121 | Q2QLG9 | 1655 | CTTB2_OTOGA Cortactin-binding protein 2 OS=Ot... | 194 | 0.0001 | 50.4 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 122 | B1AK53 | 854 | ESPN_HUMAN Espin OS=Homo sapiens (Human). GN=... | 196 | 0.047 | 41.6 | 24 | 37 | GO:0005903; C:brush border; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0031941; C:filamentous actin; ISS:UniProtKB.::GO:0032420; C:stereocilium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB. | | | | | | | | | | GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW. | 123 | Q99728 | 777 | BARD1_HUMAN BRCA1-associated RING domain prot... | 79 | 0.0001 | 50.1 | 39 | 58 | GO:0070531; C:BRCA1-A complex; IDA:UniProtKB.::GO:0031436; C:BRCA1-BARD1 complex; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003723; F:RNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; NAS:UniProtKB.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0031441; P:negative regulation of mRNA 3'-end processing; NAS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; NAS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0042325; P:regulation of phosphorylation; IMP:UniProtKB.::GO:0001894; P:tissue homeostasis; TAS:UniProtKB. | 124 | Q09YI1 | 1641 | CTTB2_SHEEP Cortactin-binding protein 2 OS=Ov... | 190 | 0.0001 | 50.4 | 29 | 43 | | | | | | | | | | | | | | | | | | | | | | 125 | Q59H18 | 835 | TNI3K_HUMAN Serine/threonine-protein kinase T... | 56 | 0.13 | 40.4 | 41 | 55 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031013; F:troponin I binding; IPI:UniProtKB. | | | | | | | | | | | 126 | A0M8S4 | 1663 | CTTB2_PAPAN Cortactin-binding protein 2 OS=Pa... | 191 | 0.0001 | 50.1 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 127 | Q2IBA2 | 1662 | CTTB2_CHLAE Cortactin-binding protein 2 OS=Ch... | 191 | 0.0002 | 50.1 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 128 | Q07DY4 | 1663 | CTTB2_COLGU Cortactin-binding protein 2 OS=Co... | 191 | 0.0002 | 50.1 | 28 | 44 | | | | | | | | | | | | | | | | | | | | | | 129 | Q9D119 | 154 | PPR27_MOUSE Protein phosphatase 1 regulatory ... | 159 | 0.0002 | 47 | 27 | 46 | | | | | | | | | | | GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. | 130 | Q6AWW5 | 524 | Y5262_ARATH Ankyrin repeat-containing protein... | 148 | 0.0002 | 49.7 | 26 | 48 | GO:0005783; C:endoplasmic reticulum; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | | 131 | O89019 | 1062 | INVS_MOUSE Inversin OS=Mus musculus (Mouse). ... | 156 | 0.006 | 44.7 | 29 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060971; P:embryonic heart tube left/right pattern formation; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 132 | Q8N6D5 | 301 | ANR29_HUMAN Ankyrin repeat domain-containing ... | 192 | 0.0002 | 48.5 | 25 | 44 | | | | | | | | | | | | | | | | | | | | | | 133 | Q86WC6 | 154 | PPR27_HUMAN Protein phosphatase 1 regulatory ... | 160 | 0.0002 | 46.6 | 27 | 45 | | | | | | | | | | | GO:0019902; F:phosphatase binding; IDA:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB. | 134 | Q09YJ3 | 1642 | CTTB2_MUNMU Cortactin-binding protein 2 OS=Mu... | 191 | 0.0002 | 49.7 | 28 | 43 | | | | | | | | | | | | | | | | | | | | | | 135 | P42773 | 168 | CDN2C_HUMAN Cyclin-dependent kinase 4 inhibit... | 89 | 0.0002 | 47 | 36 | 52 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0006917; P:induction of apoptosis; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL. | 136 | Q5DU14 | 1919 | MYO16_MOUSE Unconventional myosin-XVI OS=Mus ... | 232 | 0.0002 | 49.7 | 25 | 41 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0005654; C:nucleoplasm; ISS:HGNC.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0005886; C:plasma membrane; ISS:HGNC. | | | | | | | | | | GO:0051015; F:actin filament binding; ISS:HGNC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | GO:0021549; P:cerebellum development; ISS:HGNC.::GO:0008285; P:negative regulation of cell proliferation; ISS:HGNC.::GO:0045749; P:negative regulation of S phase of mitotic cell cycle; ISS:HGNC. | 137 | Q865U8 | 319 | ANKR1_PIG Ankyrin repeat domain-containing pr... | 196 | 0.017 | 42.4 | 27 | 46 | GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL. | | | | | | | | | | GO:0003779; F:actin binding; IPI:BHF-UCL.::GO:0031432; F:titin binding; IPI:BHF-UCL. | | | | | | | | | | | 138 | Q8N9V6 | 530 | ANR53_HUMAN Ankyrin repeat domain-containing ... | 126 | 0.0002 | 48.9 | 30 | 47 | | | | | | | | | | | | | | | | | | | | | | 139 | Q9TU71 | 319 | ANKR1_RABIT Ankyrin repeat domain-containing ... | 196 | 0.11 | 40 | 26 | 46 | | | | | | | | | | | | | | | | | | | | | | 140 | F8W2M1 | 904 | HACE1_DANRE E3 ubiquitin-protein ligase HACE1... | 244 | 0.0003 | 49.3 | 27 | 43 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006944; P:cellular membrane fusion; ISS:UniProtKB.::GO:0007030; P:Golgi organization; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0030334; P:regulation of cell migration; ISS:UniProtKB. | 141 | Q4UKJ3 | 124 | Y1087_RICFE Putative ankyrin repeat protein R... | 82 | 0.0003 | 46.2 | 33 | 56 | | | | | | | | | | | | | | | | | | | | | | 142 | Q7TQP6 | 835 | TNI3K_RAT Serine/threonine-protein kinase TNN... | 88 | 1.4 | 37 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 143 | Q04861 | 983 | NFKB1_CHICK Nuclear factor NF-kappa-B p105 su... | 170 | 0.0003 | 48.9 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0051059; F:NF-kappaB binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0035419; P:activation of MAPK activity involved in innate immune response; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0035681; P:toll-like receptor 15 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0035682; P:toll-like receptor 21 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0034146; P:toll-like receptor 5 signaling pathway; TAS:Reactome.::GO:0034154; P:toll-like receptor 7 signaling pathway; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 144 | Q502K3 | 1071 | ANR52_DANRE Serine/threonine-protein phosphat... | 55 | 7.9 | 34.7 | 35 | 49 | | | | | | | | | | | | | | | | | | | | | | 145 | Q2QL82 | 1647 | CTTB2_MICMU Cortactin-binding protein 2 OS=Mi... | 192 | 0.0003 | 48.9 | 29 | 43 | | | | | | | | | | | | | | | | | | | | | | 146 | P59672 | 1150 | ANS1A_MOUSE Ankyrin repeat and SAM domain-con... | 226 | 0.09 | 40.8 | 27 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:UniProtKB. | | | | | | | | | | GO:0046875; F:ephrin receptor binding; IPI:UniProtKB. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0016322; P:neuron remodeling; IMP:UniProtKB.::GO:0006929; P:substrate-dependent cell migration; IDA:UniProtKB. | 147 | O75832 | 226 | PSD10_HUMAN 26S proteasome non-ATPase regulat... | 200 | 0.0004 | 47 | 28 | 42 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 148 | Q505D1 | 1053 | ANR28_MOUSE Serine/threonine-protein phosphat... | 226 | 9.9 | 34.3 | 23 | 41 | GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 149 | Q9ZU96 | 532 | Y2168_ARATH Ankyrin repeat-containing protein... | 76 | 0.0004 | 48.1 | 38 | 54 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | | 150 | Q9FIT8 | 828 | AGD1_ARATH ADP-ribosylation factor GTPase-act... | 97 | 0.0004 | 48.5 | 33 | 48 | GO:0030139; C:endocytic vesicle; IDA:TAIR.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IMP:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 151 | O70445 | 765 | BARD1_MOUSE BRCA1-associated RING domain prot... | 69 | 0.0006 | 47.8 | 41 | 59 | GO:0031436; C:BRCA1-BARD1 complex; ISS:UniProtKB.::GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0046826; P:negative regulation of protein export from nucleus; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0042325; P:regulation of phosphorylation; ISS:UniProtKB. |