rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q5R685 | 724 | P85A_PONAB Phosphatidylinositol 3-kinase regu... | 178 | 0.000002 | 55.1 | 24 | 52 | GO:0005942; C:phosphatidylinositol 3-kinase complex; IEA:InterPro. | | | | | | | | | | GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 212 | O74335 | 361 | RGA5_SCHPO Rho-GTPase-activating protein 5 OS... | 188 | 0.000003 | 53.1 | 28 | 45 | GO:0051286; C:cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:PomBase. | | | | | | | | | | GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 213 | Q55CK2 | 877 | MGP2_DICDI Mental retardation GTPase activati... | 214 | 0.000004 | 53.9 | 28 | 43 | GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033298; P:contractile vacuole organization; IGI:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase. | 214 | Q9C0H5 | 1083 | RHG39_HUMAN Rho GTPase-activating protein 39 ... | 169 | 0.000005 | 53.5 | 28 | 43 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 215 | Q54GD0 | 920 | MGP1_DICDI Mental retardation GTPase activati... | 218 | 0.000006 | 53.1 | 24 | 44 | GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033298; P:contractile vacuole organization; IMP:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 216 | B2RWW0 | 714 | TAGAP_MOUSE T-cell activation Rho GTPase-acti... | 190 | 0.000009 | 52.4 | 28 | 49 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 217 | P59281 | 1107 | RHG39_MOUSE Rho GTPase-activating protein 39 ... | 138 | 0.00001 | 52 | 29 | 43 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 218 | Q8K2H3 | 851 | FA13B_MOUSE Protein FAM13B OS=Mus musculus (M... | 181 | 0.00002 | 52 | 26 | 48 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 219 | O43027 | 733 | RGA6_SCHPO Probable Rho-GTPase-activating pro... | 188 | 0.00003 | 51.2 | 23 | 44 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 220 | Q9NYF5 | 915 | FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H... | 181 | 0.00003 | 50.8 | 26 | 48 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 221 | P26450 | 724 | P85A_MOUSE Phosphatidylinositol 3-kinase regu... | 156 | 0.0002 | 48.5 | 24 | 49 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:MGI.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB. | | | | | | | | | | GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0034644; P:cellular response to UV; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0001953; P:negative regulation of cell-matrix adhesion; IGI:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IGI:MGI.::GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI. | 222 | P23727 | 724 | P85A_BOVIN Phosphatidylinositol 3-kinase regu... | 158 | 0.0004 | 47 | 25 | 49 | GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB. | | | | | | | | | | GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; IMP:BHF-UCL. | 223 | Q12128 | 409 | BAG7_YEAST Rho-GTPase-activating protein BAG7... | 186 | 0.0005 | 46.6 | 26 | 46 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 224 | Q553X3 | 799 | GACI_DICDI Rho GTPase-activating protein gacI... | 213 | 0.002 | 45.1 | 21 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 225 | Q9P3B1 | 374 | YIL2_SCHPO Putative Rho GTPase-activating pro... | 137 | 0.002 | 44.3 | 28 | 45 | GO:0005794; C:Golgi apparatus; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 226 | Q1ZXE1 | 896 | GACM_DICDI Rho GTPase-activating protein gacM... | 89 | 0.007 | 43.1 | 27 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 227 | Q01968 | 901 | OCRL_HUMAN Inositol polyphosphate 5-phosphata... | 153 | 0.019 | 42 | 24 | 43 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; TAS:ProtInc.::GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc. | | | | | | | | | | GO:0004437; F:inositol or phosphatidylinositol phosphatase activity; TAS:ProtInc.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 228 | Q54BP9 | 520 | GACV_DICDI Rho GTPase-activating protein gacV... | 113 | 0.023 | 41.6 | 30 | 49 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 229 | Q09697 | 777 | RGA8_SCHPO Rho-GTPase-activating protein 8 OS... | 176 | 0.028 | 41.2 | 26 | 44 | GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase. | | | | | | | | | | GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IGI:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 230 | Q54VW7 | 1203 | GACGG_DICDI Rho GTPase-activating protein gac... | 183 | 0.032 | 41.2 | 24 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 231 | Q8K337 | 993 | I5P2_MOUSE Type II inositol 1,4,5-trisphospha... | 91 | 0.26 | 38.1 | 27 | 45 | GO:0005829; C:cytosol; IDA:MGI.::GO:0016021; C:integral to membrane; IDA:MGI. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0070613; P:regulation of protein processing; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 232 | Q54QB9 | 1312 | GACG_DICDI Rho GTPase-activating protein gacG... | 188 | 0.28 | 38.1 | 20 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 233 | Q8K285 | 873 | FCHO1_MOUSE FCH domain only protein 1 OS=Mus ... | 151 | 0.3 | 38.1 | 25 | 42 | | | | | | | | | | | | | | | | | | | | | | 234 | P32019 | 993 | I5P2_HUMAN Type II inositol 1,4,5-trisphospha... | 91 | 0.35 | 37.7 | 29 | 46 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 235 | O14526 | 889 | FCHO1_HUMAN FCH domain only protein 1 OS=Homo... | 151 | 0.86 | 36.6 | 25 | 41 | GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0048268; P:clathrin coat assembly; IMP:UniProtKB.::GO:0072583; P:clathrin-mediated endocytosis; IMP:UniProtKB. | 236 | Q8IY33 | 904 | MILK2_HUMAN MICAL-like protein 2 OS=Homo sapi... | 111 | 0.99 | 36.2 | 28 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 237 | P10587 | 1979 | MYH11_CHICK Myosin-11 OS=Gallus gallus (Chick... | 109 | 1.2 | 36.2 | 27 | 53 | GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB. | | | | | | | | | | GO:0048739; P:cardiac muscle fiber development; ISS:UniProtKB.::GO:0048251; P:elastic fiber assembly; ISS:UniProtKB.::GO:0030241; P:skeletal muscle myosin thick filament assembly; ISS:UniProtKB.::GO:0006939; P:smooth muscle contraction; ISS:UniProtKB. | 238 | P36022 | 4092 | DYHC_YEAST Dynein heavy chain, cytoplasmic OS... | 37 | 1.4 | 36.2 | 46 | 62 | GO:0000235; C:astral microtubule; IDA:SGD.::GO:0005938; C:cell cortex; IDA:SGD.::GO:0005868; C:cytoplasmic dynein complex; TAS:SGD.::GO:0005816; C:spindle pole body; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0003777; F:microtubule motor activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000132; P:establishment of mitotic spindle orientation; IGI:SGD.::GO:0000741; P:karyogamy; IEA:UniProtKB-KW.::GO:0000022; P:mitotic spindle elongation; TAS:SGD.::GO:0030473; P:nuclear migration along microtubule; TAS:SGD. | 239 | P35749 | 1972 | MYH11_HUMAN Myosin-11 OS=Homo sapiens (Human)... | 129 | 1.4 | 35.8 | 26 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005859; C:muscle myosin complex; TAS:ProtInc.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; IMP:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048739; P:cardiac muscle fiber development; IMP:UniProtKB.::GO:0048251; P:elastic fiber assembly; IMP:UniProtKB.::GO:0030241; P:skeletal muscle myosin thick filament assembly; ISS:UniProtKB.::GO:0006939; P:smooth muscle contraction; ISS:UniProtKB. | 240 | O08638 | 1972 | MYH11_MOUSE Myosin-11 OS=Mus musculus (Mouse)... | 111 | 1.8 | 35.4 | 26 | 53 | GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030016; C:myofibril; IEA:UniProtKB-SubCell.::GO:0032982; C:myosin filament; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0008307; F:structural constituent of muscle; ISS:UniProtKB. | | | | | | | | | | GO:0048739; P:cardiac muscle fiber development; ISS:UniProtKB.::GO:0048251; P:elastic fiber assembly; ISS:UniProtKB.::GO:0030241; P:skeletal muscle myosin thick filament assembly; ISS:UniProtKB.::GO:0006939; P:smooth muscle contraction; ISS:UniProtKB. | 241 | Q8CBC4 | 711 | CNST_MOUSE Consortin OS=Mus musculus (Mouse).... | 111 | 2.4 | 35 | 27 | 45 | GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.::GO:0030133; C:transport vesicle; ISS:UniProtKB. | | | | | | | | | | GO:0071253; F:connexin binding; IDA:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0042998; P:positive regulation of Golgi to plasma membrane protein transport; ISS:UniProtKB. |