| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P49049 | 468 | IMP2_CAEEL Intramembrane protease 2 OS=Caenor... | 260 | 6e-23 | 105 | 30 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0018996; P:molting cycle, collagen and cuticulin-based cuticle; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 2 | Q9UTA3 | 295 | YL8H_SCHPO Probable intramembrane protease C2... | 71 | 0.005 | 42.7 | 38 | 55 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; NAS:PomBase. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 3 | P34248 | 587 | YKK0_YEAST Probable intramembrane protease YK... | 118 | 0.000000000000004 | 82 | 36 | 57 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 4 | Q9D8V0 | 378 | HM13_MOUSE Minor histocompatibility antigen H... | 65 | 0.000000007 | 61.6 | 43 | 60 | GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; ISS:UniProtKB. | 5 | Q8TCT9 | 377 | HM13_HUMAN Minor histocompatibility antigen H... | 98 | 0.000000004 | 62.4 | 35 | 51 | GO:0009986; C:cell surface; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0033619; P:membrane protein proteolysis; IDA:UniProtKB. | 6 | Q9JJF9 | 523 | SPP2A_MOUSE Signal peptide peptidase-like 2A ... | 113 | 0.034 | 40.8 | 26 | 41 | GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0031902; C:late endosome membrane; IDA:MGI.::GO:0005765; C:lysosomal membrane; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 7 | Q8TCT8 | 520 | SPP2A_HUMAN Signal peptide peptidase-like 2A ... | 79 | 0.99 | 36.2 | 33 | 44 | GO:0030660; C:Golgi-associated vesicle membrane; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005765; C:lysosomal membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; IDA:UniProtKB.::GO:0050776; P:regulation of immune response; IMP:UniProtKB. | 8 | Q5PQL3 | 577 | SPP2B_RAT Signal peptide peptidase-like 2B OS... | 110 | 0.0007 | 46.2 | 35 | 51 | GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 9 | Q8TCT6 | 385 | SPPL3_HUMAN Signal peptide peptidase-like 3 O... | 57 | 0.01 | 42.4 | 35 | 54 | GO:0030660; C:Golgi-associated vesicle membrane; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 10 | Q9CUS9 | 384 | SPPL3_MOUSE Signal peptide peptidase-like 3 O... | 57 | 0.01 | 42.4 | 35 | 54 | GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 11 | Q8TCT7 | 592 | SPP2B_HUMAN Signal peptide peptidase-like 2B ... | 112 | 0.073 | 39.7 | 35 | 51 | GO:0010008; C:endosome membrane; IDA:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; IDA:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005765; C:lysosomal membrane; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; IMP:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; IDA:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; IDA:UniProtKB.::GO:0050776; P:regulation of immune response; IMP:UniProtKB. | 12 | Q5F383 | 596 | SPP2B_CHICK Signal peptide peptidase-like 2B ... | 112 | 0.001 | 45.4 | 34 | 48 | GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 13 | Q3TD49 | 578 | SPP2B_MOUSE Signal peptide peptidase-like 2B ... | 110 | 0.0003 | 47.4 | 35 | 51 | GO:0010008; C:endosome membrane; ISS:UniProtKB.::GO:0030660; C:Golgi-associated vesicle membrane; ISS:UniProtKB.::GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005765; C:lysosomal membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0042500; F:aspartic endopeptidase activity, intramembrane cleaving; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0031293; P:membrane protein intracellular domain proteolysis; ISS:UniProtKB.::GO:0050776; P:regulation of immune response; ISS:UniProtKB. | 14 | Q8IUH8 | 684 | SPP2C_HUMAN Signal peptide peptidase-like 2C ... | 34 | 1.2 | 35.8 | 47 | 68 | GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 15 | A2A6C4 | 690 | SPP2C_MOUSE Signal peptide peptidase-like 2C ... | 34 | 1.1 | 35.8 | 44 | 68 | GO:0071458; C:integral to cytosolic side of endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0071556; C:integral to lumenal side of endoplasmic reticulum membrane; ISS:UniProtKB. | | | | | | | | | | GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 16 | Q9NX61 | 479 | T161A_HUMAN Transmembrane protein 161A OS=Hom... | 95 | 0.98 | 35.8 | 28 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0034599; P:cellular response to oxidative stress; IDA:BHF-UCL.::GO:0034644; P:cellular response to UV; IDA:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; IMP:BHF-UCL.::GO:0045739; P:positive regulation of DNA repair; IMP:BHF-UCL.::GO:0032526; P:response to retinoic acid; IDA:BHF-UCL. | 17 | P31565 | 65 | CCSA_OENBE Cytochrome c biogenesis protein cc... | 61 | 2.5 | 32 | 34 | 54 | GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.::GO:0008535; P:respiratory chain complex IV assembly; IEA:InterPro. | 18 | O75452 | 317 | RDH16_HUMAN Retinol dehydrogenase 16 OS=Homo ... | 47 | 2.9 | 34.3 | 36 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; TAS:ProtInc. | | | | | | | | | | GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0006629; P:lipid metabolic process; TAS:ProtInc. |
