| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q9PUN2 | 731 | SMUF1_XENLA E3 ubiquitin-protein ligase SMURF... | 92 | 0.23 | 35.8 | 26 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0007398; P:ectoderm development; TAS:UniProtKB.::GO:0030514; P:negative regulation of BMP signaling pathway; TAS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 92 | Q8C0D4 | 838 | RHG12_MOUSE Rho GTPase-activating protein 12 ... | 86 | 0.23 | 35.8 | 34 | 42 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 93 | B6RSP1 | 1197 | PKHA7_DANRE Pleckstrin homology domain-contai... | 86 | 0.33 | 35.4 | 22 | 42 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB. | | | | | | | | | | GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB. | 94 | Q9VDW6 | 3598 | DMDA_DROME Dystrophin, isoforms A/C/F/G/H OS=... | 37 | 0.36 | 35.4 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:UniProtKB.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 95 | Q9VCR6 | 608 | SAV_DROME Scaffold protein salvador OS=Drosop... | 84 | 0.52 | 34.7 | 25 | 40 | | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0051726; P:regulation of cell cycle; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IGI:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; TAS:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0046666; P:retinal cell programmed cell death; IMP:FlyBase.::GO:0048863; P:stem cell differentiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase. | 96 | Q7YU29 | 1051 | DMDE_DROME Dystrophin, isoform E OS=Drosophil... | 37 | 0.52 | 34.7 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 97 | Q05AA6 | 957 | DRP2_MOUSE Dystrophin-related protein 2 OS=Mu... | 35 | 0.89 | 34.3 | 40 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 98 | Q5TCQ9 | 1506 | MAGI3_HUMAN Membrane-associated guanylate kin... | 38 | 0.9 | 34.3 | 32 | 58 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB. | 99 | Q13474 | 957 | DRP2_HUMAN Dystrophin-related protein 2 OS=Ho... | 35 | 0.91 | 33.9 | 40 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007417; P:central nervous system development; TAS:ProtInc. | 100 | Q9EPA0 | 957 | DRP2_RAT Dystrophin-related protein 2 OS=Ratt... | 35 | 0.96 | 33.9 | 40 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0050808; P:synapse organization; IMP:RGD. | 101 | Q9VDW3 | 1669 | DMDB_DROME Dystrophin, isoform B OS=Drosophil... | 37 | 1 | 33.9 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 102 | Q9BYW2 | 2564 | SETD2_HUMAN Histone-lysine N-methyltransferas... | 33 | 1.2 | 33.9 | 42 | 61 | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0046914; F:transition metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 103 | Q0KI50 | 1854 | DMDD_DROME Dystrophin, isoform D OS=Drosophil... | 37 | 1.5 | 33.5 | 35 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IDA:UniProtKB.::GO:0016010; C:dystrophin-associated glycoprotein complex; IPI:FlyBase.::GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0050699; F:WW domain binding; IPI:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030010; P:establishment of cell polarity; IMP:FlyBase.::GO:0008586; P:imaginal disc-derived wing vein morphogenesis; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0046716; P:muscle cell homeostasis; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:UniProtKB.::GO:0007274; P:neuromuscular synaptic transmission; IDA:FlyBase.::GO:0046928; P:regulation of neurotransmitter secretion; IMP:UniProtKB.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IDA:FlyBase. | 104 | O75400 | 957 | PR40A_HUMAN Pre-mRNA-processing factor 40 hom... | 92 | 5.9 | 31.6 | 23 | 40 | GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 105 | Q9R1C7 | 953 | PR40A_MOUSE Pre-mRNA-processing factor 40 hom... | 92 | 6.1 | 31.6 | 23 | 40 | GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0032465; P:regulation of cytokinesis; ISS:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 106 | Q9JLV1 | 577 | BAG3_MOUSE BAG family molecular chaperone reg... | 35 | 2.8 | 32.3 | 49 | 60 | | | | | | | | | | | GO:0051087; F:chaperone binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IDA:MGI. | 107 | Q6ZUM4 | 889 | RHG27_HUMAN Rho GTPase-activating protein 27 ... | 92 | 2.9 | 32.3 | 33 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:HGNC.::GO:0017124; F:SH3 domain binding; ISS:HGNC. | | | | | | | | | | GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:HGNC.::GO:0006898; P:receptor-mediated endocytosis; ISS:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro. | 108 | Q13526 | 163 | PIN1_HUMAN Peptidyl-prolyl cis-trans isomeras... | 37 | 3.3 | 31.6 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IDA:MGI.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0032794; F:GTPase activating protein binding; IPI:BHF-UCL.::GO:0031434; F:mitogen-activated protein kinase kinase binding; IPI:BHF-UCL.::GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:BHF-UCL.::GO:0050815; F:phosphoserine binding; IDA:BHF-UCL.::GO:0050816; F:phosphothreonine binding; IDA:BHF-UCL. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:2000146; P:negative regulation of cell motility; IDA:BHF-UCL.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:BHF-UCL.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0001934; P:positive regulation of protein phosphorylation; IGI:MGI.::GO:0032321; P:positive regulation of Rho GTPase activity; IMP:BHF-UCL.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0032465; P:regulation of cytokinesis; IMP:MGI.::GO:0007088; P:regulation of mitosis; TAS:ProtInc.::GO:0060393; P:regulation of pathway-restricted SMAD protein phosphorylation; IDA:BHF-UCL. | 109 | Q5BIN5 | 163 | PIN1_BOVIN Peptidyl-prolyl cis-trans isomeras... | 37 | 3.4 | 31.6 | 35 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; ISS:AgBase. | 110 | Q8CGF7 | 1100 | TCRG1_MOUSE Transcription elongation regulato... | 44 | 3.5 | 32.3 | 32 | 50 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 111 | O14776 | 1098 | TCRG1_HUMAN Transcription elongation regulato... | 44 | 3.6 | 32.3 | 32 | 50 | GO:0005634; C:nucleus; TAS:ProtInc. | | | | | | | | | | GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc. | | | | | | | | | | | 112 | Q9VLU5 | 409 | WWOX_DROME WW domain-containing oxidoreductas... | 40 | 5.1 | 31.6 | 38 | 50 | GO:0005737; C:cytoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 113 | Q9GZV5 | 400 | WWTR1_HUMAN WW domain-containing transcriptio... | 34 | 5.8 | 31.2 | 32 | 56 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0003713; F:transcription coactivator activity; IDA:UniProtKB. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProtKB.::GO:0060390; P:regulation of SMAD protein import into nucleus; IDA:UniProtKB.::GO:0017145; P:stem cell division; IDA:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome. | 114 | Q9EPK5 | 395 | WWTR1_MOUSE WW domain-containing transcriptio... | 34 | 6.5 | 31.2 | 32 | 56 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0003714; F:transcription corepressor activity; IGI:MGI. | | | | | | | | | | GO:0060271; P:cilium morphogenesis; IMP:MGI.::GO:0032835; P:glomerulus development; IMP:MGI.::GO:0045599; P:negative regulation of fat cell differentiation; IGI:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0001649; P:osteoblast differentiation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 115 | Q9QUR7 | 165 | PIN1_MOUSE Peptidyl-prolyl cis-trans isomeras... | 35 | 7.1 | 30.4 | 37 | 54 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0032465; P:regulation of cytokinesis; IMP:MGI. | 116 | Q8IWW6 | 846 | RHG12_HUMAN Rho GTPase-activating protein 12 ... | 86 | 7.5 | 31.2 | 29 | 40 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 117 | Q80W14 | 870 | PR40B_MOUSE Pre-mRNA-processing factor 40 hom... | 47 | 8.3 | 31.2 | 30 | 53 | GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. |
