| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O43149 | 2961 | ZZEF1_HUMAN Zinc finger ZZ-type and EF-hand d... | 100 | 0.034 | 40 | 32 | 47 | | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 2 | O15020 | 2390 | SPTN2_HUMAN Spectrin beta chain, brain 2 OS=H... | 137 | 0.18 | 37.7 | 23 | 36 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0008091; C:spectrin; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005200; F:structural constituent of cytoskeleton; TAS:UniProtKB. | | | | | | | | | | GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0016192; P:vesicle-mediated transport; IDA:UniProtKB. | 3 | Q8CDM4 | 1066 | CCD73_MOUSE Coiled-coil domain-containing pro... | 133 | 0.19 | 37.4 | 26 | 48 | | | | | | | | | | | | | | | | | | | | | | 4 | Q7Z333 | 2677 | SETX_HUMAN Probable helicase senataxin OS=Hom... | 175 | 0.34 | 36.6 | 24 | 34 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IC:UniProtKB.::GO:0003678; F:DNA helicase activity; TAS:UniProtKB. | | | | | | | | | | GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0006396; P:RNA processing; TAS:UniProtKB. | 5 | Q9P219 | 2028 | DAPLE_HUMAN Protein Daple OS=Homo sapiens (Hu... | 162 | 0.41 | 36.6 | 25 | 38 | GO:0005737; C:cytoplasm; IEA:InterPro.::GO:0005626; C:insoluble fraction; ISS:UniProtKB. | | | | | | | | | | GO:0008017; F:microtubule binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0043621; F:protein self-association; ISS:UniProtKB. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IEA:InterPro.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.::GO:0001932; P:regulation of protein phosphorylation; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 6 | Q6PCJ1 | 1232 | DCTN1_XENLA Dynactin subunit 1 OS=Xenopus lae... | 95 | 0.43 | 36.2 | 29 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030286; C:dynein complex; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003774; F:motor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 7 | Q9QXZ0 | 7354 | MACF1_MOUSE Microtubule-actin cross-linking f... | 156 | 0.48 | 36.2 | 24 | 43 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IDA:MGI.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; IDA:MGI. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0006928; P:cellular component movement; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0001707; P:mesoderm formation; IMP:MGI.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0006620; P:posttranslational protein targeting to membrane; IMP:MGI.::GO:0010632; P:regulation of epithelial cell migration; IMP:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; IMP:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IMP:MGI.::GO:0042060; P:wound healing; IMP:UniProtKB. | 8 | Q9JIX5 | 2581 | CHD8_RAT Chromodomain-helicase-DNA-binding pr... | 128 | 0.96 | 35.4 | 29 | 42 | GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0070016; F:armadillo repeat domain binding; IPI:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008013; F:beta-catenin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0008094; F:DNA-dependent ATPase activity; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB. | | | | | | | | | | GO:0043044; P:ATP-dependent chromatin remodeling; ISS:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 9 | Q09XV5 | 2582 | CHD8_MOUSE Chromodomain-helicase-DNA-binding ... | 229 | 1.1 | 35 | 24 | 37 | GO:0071339; C:MLL1 complex; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0008013; F:beta-catenin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0003678; F:DNA helicase activity; ISS:UniProtKB.::GO:0008094; F:DNA-dependent ATPase activity; ISS:UniProtKB.::GO:0035064; F:methylated histone residue binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB. | | | | | | | | | | GO:0043044; P:ATP-dependent chromatin remodeling; ISS:UniProtKB.::GO:0060070; P:canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045945; P:positive regulation of transcription from RNA polymerase III promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 10 | D3ZHV2 | 5430 | MACF1_RAT Microtubule-actin cross-linking fac... | 156 | 1.7 | 34.7 | 24 | 42 | GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005874; C:microtubule; ISS:UniProtKB.::GO:0032587; C:ruffle membrane; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; ISS:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB. | 11 | Q5REF4 | 1174 | F178A_PONAB Protein FAM178A OS=Pongo abelii (... | 140 | 2 | 34.3 | 21 | 38 | | | | | | | | | | | | | | | | | | | | | | 12 | A4GSN8 | 2093 | NUA_ARATH Nuclear-pore anchor OS=Arabidopsis ... | 175 | 2.8 | 33.9 | 25 | 38 | GO:0009507; C:chloroplast; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR. | | | | | | | | | | GO:0005515; F:protein binding; IPI:TAIR. | | | | | | | | | | GO:0009910; P:negative regulation of flower development; IMP:TAIR.::GO:0033234; P:negative regulation of protein sumoylation; IMP:TAIR.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:TAIR.::GO:0006606; P:protein import into nucleus; IEA:InterPro.::GO:0048443; P:stamen development; IMP:TAIR. | 13 | Q6FMJ3 | 1252 | MYO3_CANGA Myosin-3 OS=NRRL Y-65) (Yeast) (To... | 121 | 3 | 33.5 | 24 | 38 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 14 | A1VG83 | 1079 | IF2_DESVV Translation initiation factor IF-2 ... | 94 | 3.5 | 33.5 | 30 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 15 | Q72ER1 | 1079 | IF2_DESVH Translation initiation factor IF-2 ... | 94 | 3.7 | 33.5 | 30 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW. | | | | | | | | | | | 16 | Q2KN99 | 1118 | CYTSA_RAT Cytospin-A OS=Rattus norvegicus (Ra... | 167 | 3.8 | 33.1 | 28 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005921; C:gap junction; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW. | 17 | Q8IX21 | 1173 | F178A_HUMAN Protein FAM178A OS=Homo sapiens (... | 140 | 4 | 33.1 | 21 | 38 | | | | | | | | | | | | | | | | | | | | | | 18 | P19158 | 3079 | IRA2_YEAST Inhibitory regulator protein IRA2 ... | 118 | 5.2 | 33.1 | 25 | 45 | GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD. | | | | | | | | | | GO:0005099; F:Ras GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0030818; P:negative regulation of cAMP biosynthetic process; IMP:SGD.::GO:0046580; P:negative regulation of Ras protein signal transduction; IMP:SGD.::GO:0006950; P:response to stress; IMP:SGD.::GO:0007165; P:signal transduction; IEA:InterPro. | 19 | Q01970 | 1234 | PLCB3_HUMAN 1-phosphatidylinositol 4,5-bispho... | 51 | 7.3 | 32.3 | 39 | 49 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IPI:BHF-UCL.::GO:0004435; F:phosphatidylinositol phospholipase C activity; IEA:EC.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.::GO:0007268; P:synaptic transmission; TAS:Reactome. | 20 | Q9UPN3 | 7388 | MACF1_HUMAN Microtubule-actin cross-linking f... | 156 | 8.2 | 32.3 | 23 | 42 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005874; C:microtubule; IDA:UniProtKB.::GO:0032587; C:ruffle membrane; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; NAS:UniProtKB.::GO:0016887; F:ATPase activity; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008017; F:microtubule binding; NAS:UniProtKB. | | | | | | | | | | GO:0007050; P:cell cycle arrest; IEA:InterPro.::GO:0043001; P:Golgi to plasma membrane protein transport; IDA:UniProtKB.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0010632; P:regulation of epithelial cell migration; ISS:UniProtKB.::GO:0051893; P:regulation of focal adhesion assembly; ISS:UniProtKB.::GO:0032886; P:regulation of microtubule-based process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.::GO:0042060; P:wound healing; ISS:UniProtKB. | 21 | Q9LVN1 | 1266 | FH13_ARATH Formin-like protein 13 OS=Arabidop... | 118 | 8.5 | 32.3 | 25 | 42 | | | | | | | | | | | GO:0003779; F:actin binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IEA:InterPro. | 22 | Q14203 | 1278 | DCTN1_HUMAN Dynactin subunit 1 OS=Homo sapien... | 135 | 8.5 | 32.3 | 27 | 39 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0000776; C:kinetochore; IDA:UniProtKB.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0000922; C:spindle pole; IDA:UniProtKB. | | | | | | | | | | GO:0003774; F:motor activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0007067; P:mitosis; NAS:ProtInc.::GO:0007399; P:nervous system development; NAS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 23 | Q4IL82 | 1904 | INO80_GIBZE Putative DNA helicase INO80 OS=(W... | 143 | 9.6 | 32 | 22 | 41 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
