rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | Q5UQI7 | 276 | YR838_MIMIV Putative ankyrin repeat protein R... | 104 | 0.004 | 44.3 | 32 | 48 | | | | | | | | | | | | | | | | | | | | | | 92 | Q91WD2 | 727 | TRPV6_MOUSE Transient receptor potential cati... | 156 | 1.5 | 36.6 | 30 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005262; F:calcium channel activity; IDA:MGI.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | | 93 | Q5UPF8 | 879 | YL088_MIMIV Putative ankyrin repeat protein L... | 201 | 0.54 | 38.1 | 21 | 43 | | | | | | | | | | | | | | | | | | | | | | 94 | Q59H18 | 835 | TNI3K_HUMAN Serine/threonine-protein kinase T... | 91 | 0.047 | 41.6 | 33 | 51 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0031013; F:troponin I binding; IPI:UniProtKB. | | | | | | | | | | | 95 | Q812A3 | 306 | ANR23_MOUSE Ankyrin repeat domain-containing ... | 178 | 0.00007 | 50.1 | 30 | 43 | GO:0031674; C:I band; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IDA:MGI. | 96 | O75832 | 226 | PSD10_HUMAN 26S proteasome non-ATPase regulat... | 187 | 0.00007 | 49.3 | 30 | 46 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005838; C:proteasome regulatory particle; TAS:ProtInc. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; IDA:UniProtKB.::GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:Reactome.::GO:0010467; P:gene expression; TAS:Reactome.::GO:0000216; P:M/G1 transition of mitotic cell cycle; TAS:Reactome.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; IDA:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; IMP:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; IDA:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070682; P:proteasome regulatory particle assembly; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; TAS:Reactome.::GO:0006521; P:regulation of cellular amino acid metabolic process; TAS:Reactome.::GO:0000084; P:S phase of mitotic cell cycle; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 97 | Q6PFX9 | 1320 | TNKS1_MOUSE Tankyrase-1 OS=Mus musculus (Mous... | 121 | 8.7 | 34.3 | 31 | 43 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; ISS:UniProtKB. | | | | | | | | | | GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 98 | Q502K3 | 1071 | ANR52_DANRE Serine/threonine-protein phosphat... | 257 | 0.45 | 38.5 | 26 | 39 | | | | | | | | | | | | | | | | | | | | | | 99 | Q6JAN1 | 1081 | INVS_CANFA Inversin OS=Canis familiaris (Dog)... | 168 | 9.9 | 34.3 | 27 | 41 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 100 | Q9Z2X3 | 231 | PSD10_RAT 26S proteasome non-ATPase regulator... | 187 | 0.00009 | 48.9 | 30 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 101 | Q9Y283 | 1065 | INVS_HUMAN Inversin OS=Homo sapiens (Human). ... | 59 | 5.1 | 35 | 37 | 54 | GO:0005929; C:cilium; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 102 | Q876L4 | 730 | AKR2_SACBA Probable palmitoyltransferase AKR2... | 182 | 0.00009 | 50.4 | 30 | 41 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 103 | O95271 | 1327 | TNKS1_HUMAN Tankyrase-1 OS=Homo sapiens (Huma... | 121 | 8.4 | 34.3 | 31 | 43 | GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:BHF-UCL.::GO:0000784; C:nuclear chromosome, telomeric region; IDA:BHF-UCL.::GO:0031965; C:nuclear membrane; TAS:BHF-UCL.::GO:0005643; C:nuclear pore; TAS:BHF-UCL.::GO:0000242; C:pericentriolar material; TAS:BHF-UCL. | | | | | | | | | | GO:0003950; F:NAD+ ADP-ribosyltransferase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:BHF-UCL. | | | | | | | | | | GO:0007052; P:mitotic spindle organization; TAS:BHF-UCL.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0043392; P:negative regulation of DNA binding; IDA:BHF-UCL.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0032212; P:positive regulation of telomere maintenance via telomerase; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0070213; P:protein auto-ADP-ribosylation; IDA:UniProtKB.::GO:0070198; P:protein localization to chromosome, telomeric region; IMP:BHF-UCL.::GO:0070212; P:protein poly-ADP-ribosylation; IDA:BHF-UCL.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; TAS:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 104 | P40480 | 1083 | HOS4_YEAST Protein HOS4 OS=Saccharomyces cere... | 111 | 0.078 | 41.2 | 30 | 45 | GO:0034967; C:Set3 complex; IDA:SGD. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0016575; P:histone deacetylation; IDA:SGD.::GO:0045835; P:negative regulation of meiosis; IPI:SGD. | 105 | Q8WWX0 | 329 | ASB5_HUMAN Ankyrin repeat and SOCS box protei... | 62 | 0.71 | 37.4 | 37 | 56 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 106 | Q7XUW4 | 719 | KOR2_ORYSJ Potassium channel KOR2 OS=Oryza sa... | 174 | 0.0001 | 50.4 | 30 | 42 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro. | | | | | | | | | | | 107 | Q96Q27 | 587 | ASB2_HUMAN Ankyrin repeat and SOCS box protei... | 145 | 2.2 | 36.2 | 27 | 42 | | | | | | | | | | | | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 108 | Q8VHQ3 | 568 | PP16B_MOUSE Protein phosphatase 1 regulatory ... | 227 | 0.0001 | 50.1 | 26 | 41 | GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0051489; P:regulation of filopodium assembly; ISS:UniProtKB. | 109 | P39010 | 764 | AKR1_YEAST Palmitoyltransferase AKR1 OS=Sacch... | 167 | 0.0001 | 50.1 | 28 | 44 | GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016409; F:palmitoyltransferase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0018345; P:protein palmitoylation; IDA:SGD.::GO:0006612; P:protein targeting to membrane; IMP:SGD.::GO:0030100; P:regulation of endocytosis; IMP:SGD.::GO:0010969; P:regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion; IGI:SGD. | 110 | Q9DBR7 | 1029 | MYPT1_MOUSE Protein phosphatase 1 regulatory ... | 243 | 0.0001 | 50.1 | 28 | 40 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; IMP:MGI.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB.::GO:0046822; P:regulation of nucleocytoplasmic transport; IMP:MGI. | 111 | Q9Z2X2 | 231 | PSD10_MOUSE 26S proteasome non-ATPase regulat... | 205 | 0.0001 | 48.5 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007253; P:cytoplasmic sequestering of NF-kappaB; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0043518; P:negative regulation of DNA damage response, signal transduction by p53 class mediator; ISS:UniProtKB.::GO:0043409; P:negative regulation of MAPK cascade; ISS:UniProtKB.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090201; P:negative regulation of release of cytochrome c from mitochondria; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0045737; P:positive regulation of cyclin-dependent protein kinase activity; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0070682; P:proteasome regulatory particle assembly; ISS:UniProtKB. | 112 | Q5UP39 | 468 | YR873_MIMIV Putative ankyrin repeat protein R... | 259 | 0.43 | 38.5 | 21 | 41 | | | | | | | | | | | | | | | | | | | | | | 113 | E5RJM6 | 399 | ANR65_HUMAN Ankyrin repeat domain-containing ... | 81 | 4.1 | 35 | 36 | 49 | | | | | | | | | | | | | | | | | | | | | | 114 | Q9NQA5 | 729 | TRPV5_HUMAN Transient receptor potential cati... | 254 | 0.0001 | 50.1 | 26 | 41 | GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005262; F:calcium channel activity; ISS:UniProtKB.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051262; P:protein tetramerization; ISS:UniProtKB. | 115 | Q5BKI6 | 318 | ANKR1_XENTR Ankyrin repeat domain-containing ... | 170 | 0.0001 | 48.9 | 28 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 116 | Q8UVC1 | 1021 | INVS_DANRE Inversin OS=Danio rerio (Zebrafish... | 59 | 4.9 | 35 | 36 | 56 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 117 | Q10728 | 1032 | MYPT1_RAT Protein phosphatase 1 regulatory su... | 243 | 0.0002 | 50.1 | 28 | 40 | GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0000776; C:kinetochore; ISS:UniProtKB.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0004857; F:enzyme inhibitor activity; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB.::GO:0004721; F:phosphoprotein phosphatase activity; IDA:RGD. | | | | | | | | | | GO:0051297; P:centrosome organization; ISS:UniProtKB.::GO:0007067; P:mitosis; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB. | 118 | P55273 | 166 | CDN2D_HUMAN Cyclin-dependent kinase 4 inhibit... | 119 | 0.089 | 38.9 | 30 | 50 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0004861; F:cyclin-dependent protein kinase inhibitor activity; IDA:BHF-UCL.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:BHF-UCL.::GO:0048102; P:autophagic cell death; IMP:BHF-UCL.::GO:0007050; P:cell cycle arrest; IDA:BHF-UCL.::GO:0000731; P:DNA synthesis involved in DNA repair; IMP:BHF-UCL.::GO:0000080; P:G1 phase of mitotic cell cycle; TAS:Reactome.::GO:0000082; P:G1/S transition of mitotic cell cycle; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:BHF-UCL.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IDA:BHF-UCL.::GO:0032526; P:response to retinoic acid; IMP:BHF-UCL.::GO:0009411; P:response to UV; IMP:BHF-UCL.::GO:0033280; P:response to vitamin D; IMP:BHF-UCL. | 119 | Q8T2Q0 | 698 | ZDHC6_DICDI Putative ZDHHC-type palmitoyltran... | 99 | 2 | 36.2 | 27 | 46 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 120 | O89019 | 1062 | INVS_MOUSE Inversin OS=Mus musculus (Mouse). ... | 195 | 9.8 | 34.3 | 27 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0060971; P:embryonic heart tube left/right pattern formation; IMP:MGI.::GO:0001822; P:kidney development; IMP:MGI.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0031016; P:pancreas development; IMP:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 121 | Q9ULH0 | 1771 | KDIS_HUMAN Kinase D-interacting substrate of ... | 139 | 0.69 | 38.1 | 27 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome. |