| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | O43001 | 1076 | SYJ1_SCHPO Inositol-1,4,5-trisphosphate 5-pho... | 109 | 0.00005 | 49.3 | 33 | 51 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0006897; P:endocytosis; NAS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 2 | P32019 | 993 | I5P2_HUMAN Type II inositol 1,4,5-trisphospha... | 90 | 0.0001 | 48.1 | 31 | 50 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0016020; C:membrane; IDA:UniProtKB.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 3 | Q01968 | 901 | OCRL_HUMAN Inositol polyphosphate 5-phosphata... | 142 | 0.0002 | 47.4 | 30 | 44 | GO:0030136; C:clathrin-coated vesicle; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005795; C:Golgi stack; TAS:ProtInc.::GO:0005798; C:Golgi-associated vesicle; TAS:ProtInc. | | | | | | | | | | GO:0004437; F:inositol or phosphatidylinositol phosphatase activity; TAS:ProtInc.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 4 | Q8K337 | 993 | I5P2_MOUSE Type II inositol 1,4,5-trisphospha... | 89 | 0.001 | 45.1 | 31 | 48 | GO:0005829; C:cytosol; IDA:MGI.::GO:0016021; C:integral to membrane; IDA:MGI. | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:UniProtKB.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:UniProtKB. | | | | | | | | | | GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0070613; P:regulation of protein processing; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030317; P:sperm motility; IMP:MGI.::GO:0007283; P:spermatogenesis; IMP:MGI. | 5 | O15056 | 1496 | SYNJ2_HUMAN Synaptojanin-2 OS=Homo sapiens (H... | 93 | 0.067 | 39.3 | 28 | 45 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 6 | O55207 | 1496 | SYNJ2_RAT Synaptojanin-2 OS=Rattus norvegicus... | 93 | 0.086 | 38.9 | 29 | 45 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0005881; C:cytoplasmic microtubule; IDA:RGD.::GO:0031315; C:extrinsic to mitochondrial outer membrane; IDA:RGD.::GO:0005626; C:insoluble fraction; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0032587; C:ruffle membrane; IDA:RGD. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IDA:RGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0052744; F:phosphatidylinositol monophosphate phosphatase activity; IDA:RGD.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IPI:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:RGD.::GO:0048312; P:intracellular distribution of mitochondria; IDA:RGD.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 7 | P40559 | 946 | INP51_YEAST Phosphatidylinositol 4,5-bisphosp... | 207 | 0.16 | 38.1 | 21 | 40 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:SGD. | | | | | | | | | | GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046856; P:phosphatidylinositol dephosphorylation; IDA:SGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 8 | Q9D2G5 | 1434 | SYNJ2_MOUSE Synaptojanin-2 OS=Mus musculus (M... | 93 | 0.24 | 37.4 | 30 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 9 | Q8CHC4 | 1574 | SYNJ1_MOUSE Synaptojanin-1 OS=Mus musculus (M... | 97 | 0.26 | 37.4 | 28 | 42 | GO:0030118; C:clathrin coat; TAS:MGI. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IMP:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IMP:MGI.::GO:0007612; P:learning; IMP:MGI.::GO:0046856; P:phosphatidylinositol dephosphorylation; IMP:MGI.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:MGI.::GO:0016082; P:synaptic vesicle priming; IMP:MGI.::GO:0016191; P:synaptic vesicle uncoating; IMP:MGI. | 10 | Q62910 | 1574 | SYNJ1_RAT Synaptojanin-1 OS=Rattus norvegicus... | 97 | 0.28 | 37.4 | 28 | 42 | GO:0019717; C:synaptosome; IDA:RGD. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IDA:RGD. | | | | | | | | | | GO:0007420; P:brain development; IEP:RGD.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0014015; P:positive regulation of gliogenesis; IMP:RGD.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; IMP:RGD.::GO:0034097; P:response to cytokine stimulus; IMP:RGD.::GO:0032526; P:response to retinoic acid; IMP:RGD. | 11 | Q9USQ6 | 889 | SYJ2_SCHPO Inositol-1,4,5-trisphosphate 5-pho... | 107 | 0.3 | 37 | 26 | 43 | GO:0005737; C:cytoplasm; IDA:PomBase. | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; ISS:PomBase.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC. | | | | | | | | | | GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0048017; P:inositol lipid-mediated signaling; IC:PomBase.::GO:0046856; P:phosphatidylinositol dephosphorylation; ISS:PomBase.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 12 | O43426 | 1573 | SYNJ1_HUMAN Synaptojanin-1 OS=Homo sapiens (H... | 97 | 0.32 | 37 | 28 | 42 | | | | | | | | | | | GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 13 | Q2I6J0 | 1226 | SHP2B_DANRE Phosphatidylinositol 3,4,5-trisph... | 145 | 0.36 | 37 | 25 | 41 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 14 | O18964 | 1324 | SYNJ1_BOVIN Synaptojanin-1 OS=Bos taurus (Bov... | 97 | 0.49 | 36.6 | 28 | 42 | GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:EC.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 15 | Q9SYK4 | 1136 | IP5PD_ARATH Type I inositol 1,4,5-trisphospha... | 104 | 1.1 | 35.4 | 31 | 45 | GO:0005634; C:nucleus; IDA:TAIR. | | | | | | | | | | GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:EC.::GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0010252; P:auxin homeostasis; IMP:TAIR.::GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IMP:TAIR.::GO:0009637; P:response to blue light; IEP:TAIR.::GO:0007584; P:response to nutrient; IMP:TAIR.::GO:0009611; P:response to wounding; IEP:TAIR.::GO:0048364; P:root development; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; IMP:TAIR. | 16 | Q9SKB7 | 1144 | IP5PE_ARATH Type II inositol 1,4,5-trisphosph... | 78 | 1.2 | 35 | 32 | 53 | | | | | | | | | | | GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0034485; F:phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity; IDA:TAIR.::GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IDA:TAIR. | | | | | | | | | | GO:0046855; P:inositol phosphate dephosphorylation; IDA:TAIR.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 17 | Q2I6J1 | 1266 | SHP2A_DANRE Phosphatidylinositol 3,4,5-trisph... | 96 | 3.1 | 33.9 | 27 | 45 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030509; P:BMP signaling pathway; IMP:ZFIN.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0040037; P:negative regulation of fibroblast growth factor receptor signaling pathway; IMP:ZFIN.::GO:0046854; P:phosphatidylinositol phosphorylation; IEA:InterPro. | 18 | Q9EYV3 | 234 | PYRF_RHIFH Orotidine 5'-phosphate decarboxyla... | 66 | 5.8 | 32.3 | 33 | 50 | | | | | | | | | | | GO:0004590; F:orotidine-5'-phosphate decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0006207; P:'de novo' pyrimidine base biosynthetic process; IEA:InterPro.::GO:0044205; P:'de novo' UMP biosynthetic process; IEA:InterPro. | 19 | Q9LBG3 | 1653 | PAA_STRCG Probable cell-surface antigen I/II ... | 89 | 8.3 | 32.3 | 29 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-KW.::GO:0009274; C:peptidoglycan-based cell wall; IEA:InterPro. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0044406; P:adhesion to host; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:InterPro. |
