| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P78970 | 390 | LAG1_SCHPO Sphingosine N-acyltransferase lag1... | 410 | 3e-68 | 230 | 35 | 50 | GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:PomBase.::GO:0005773; C:vacuole; IGI:GOC. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; ISS:PomBase.::GO:0042493; P:response to drug; IMP:PomBase.::GO:0009636; P:response to toxin; IMP:PomBase.::GO:0007035; P:vacuolar acidification; IGI:PomBase. | 2 | A6ZSP9 | 411 | LAG1_YEAS7 Sphingosine N-acyltransferase LAG1... | 310 | 9e-31 | 127 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC. | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 3 | P38703 | 411 | LAG1_YEAST Sphingosine N-acyltransferase LAG1... | 310 | 1e-30 | 126 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:SGD. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:SGD.::GO:0001302; P:replicative cell aging; IMP:SGD. | 4 | P28496 | 418 | LAC1_YEAST Sphingosine N-acyltransferase LAC1... | 299 | 3e-28 | 119 | 29 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:SGD. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:SGD. | 5 | A6ZZV7 | 418 | LAC1_YEAS7 Sphingosine N-acyltransferase LAC1... | 299 | 3e-28 | 119 | 29 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC. | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 6 | O59735 | 384 | LAC1_SCHPO Sphingosine N-acyltransferase lac1... | 240 | 2e-23 | 105 | 29 | 48 | GO:0030176; C:integral to endoplasmic reticulum membrane; NAS:PomBase.::GO:0005773; C:vacuole; IMP:GOC. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IEA:EC. | | | | | | | | | | GO:0071277; P:cellular response to calcium ion; IMP:PomBase.::GO:0034605; P:cellular response to heat; IMP:PomBase.::GO:0071294; P:cellular response to zinc ion; IMP:PomBase.::GO:0046513; P:ceramide biosynthetic process; ISS:PomBase.::GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0007009; P:plasma membrane organization; IMP:PomBase.::GO:0042493; P:response to drug; IMP:PomBase.::GO:0009636; P:response to toxin; IGI:PomBase.::GO:0007035; P:vacuolar acidification; IMP:PomBase.::GO:0070072; P:vacuolar proton-transporting V-type ATPase complex assembly; ISS:PomBase. | 7 | Q9LJK3 | 296 | LAG12_ARATH LAG1 longevity assurance homolog ... | 262 | 4e-20 | 94.4 | 29 | 46 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IMP:TAIR. | | | | | | | | | | GO:0042759; P:long-chain fatty acid biosynthetic process; IMP:TAIR.::GO:0002238; P:response to molecule of fungal origin; IMP:TAIR. | 8 | Q84QC0 | 284 | ASCL3_ORYSJ ASC1-like protein 3 OS=Oryza sati... | 261 | 2e-18 | 89.7 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 9 | Q9M6A3 | 308 | ASC1_SOLLC Protein ASC1 OS=Solanum lycopersic... | 182 | 4e-17 | 85.5 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 10 | Q6NQI8 | 308 | LAG13_ARATH LAG1 longevity assurance homolog ... | 273 | 6e-17 | 85.1 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IGI:TAIR. | | | | | | | | | | GO:0042761; P:very long-chain fatty acid biosynthetic process; IGI:TAIR. | 11 | Q6ZMG9 | 384 | CERS6_HUMAN Ceramide synthase 6 OS=Homo sapie... | 253 | 8e-17 | 85.9 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 12 | Q8N5B7 | 392 | CERS5_HUMAN Ceramide synthase 5 OS=Homo sapie... | 151 | 2e-16 | 84.7 | 30 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:HGNC.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:HGNC. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:HGNC.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 13 | Q6EUN0 | 309 | ASCL1_ORYSJ ASC1-like protein 1 OS=Oryza sati... | 271 | 3e-16 | 83.2 | 25 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 14 | Q5E9R6 | 393 | CERS4_BOVIN Ceramide synthase 4 OS=Bos taurus... | 265 | 4e-16 | 83.6 | 23 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 15 | Q924Z4 | 380 | CERS2_MOUSE Ceramide synthase 2 OS=Mus muscul... | 249 | 6e-16 | 83.2 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:MGI. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:MGI. | 16 | Q8C172 | 384 | CERS6_MOUSE Ceramide synthase 6 OS=Mus muscul... | 152 | 7e-16 | 82.8 | 29 | 49 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:MGI. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:MGI. | 17 | Q3ZBF8 | 380 | CERS2_BOVIN Ceramide synthase 2 OS=Bos taurus... | 250 | 0.000000000000001 | 82 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | | 18 | Q9LDF2 | 310 | LAG11_ARATH LAG1 longevity assurance homolog ... | 270 | 0.000000000000002 | 80.9 | 27 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR. | | | | | | | | | | | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 19 | Q9D6K9 | 414 | CERS5_MOUSE Ceramide synthase 5 OS=Mus muscul... | 252 | 0.000000000000002 | 82 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:HGNC.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:HGNC. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:HGNC. | 20 | Q96G23 | 380 | CERS2_HUMAN Ceramide synthase 2 OS=Homo sapie... | 249 | 0.000000000000004 | 80.5 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IDA:HPA. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 21 | Q9D6J1 | 393 | CERS4_MOUSE Ceramide synthase 4 OS=Mus muscul... | 257 | 0.00000000000001 | 79.3 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0050291; F:sphingosine N-acyltransferase activity; IDA:MGI. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:MGI. | 22 | Q6YWS8 | 303 | ASCL2_ORYSJ ASC1-like protein 2 OS=Oryza sati... | 192 | 0.0000000000002 | 74.7 | 27 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 23 | Q9HA82 | 394 | CERS4_HUMAN Ceramide synthase 4 OS=Homo sapie... | 172 | 0.0000000000004 | 74.7 | 23 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 24 | Q8W4Y5 | 303 | ASCL_SOLLC ASC1-like protein OS=Solanum lycop... | 274 | 0.000000000002 | 71.2 | 26 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 25 | Q8IU89 | 383 | CERS3_HUMAN Ceramide synthase 3 OS=Homo sapie... | 133 | 0.0000000005 | 65.1 | 26 | 47 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 26 | Q15035 | 370 | TRAM2_HUMAN Translocating chain-associated me... | 125 | 0.0000001 | 57 | 31 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0032964; P:collagen biosynthetic process; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 27 | Q924Z5 | 370 | TRAM2_MOUSE Translocating chain-associated me... | 125 | 0.0000002 | 56.6 | 32 | 50 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 28 | Q6DED0 | 373 | TR1L1_XENLA Translocating chain-associated me... | 216 | 0.0000003 | 56.2 | 23 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 29 | P27545 | 350 | CERS1_MOUSE Ceramide synthase 1 OS=Mus muscul... | 146 | 0.000002 | 53.1 | 29 | 47 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:HGNC. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; IDA:HGNC. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; IDA:HGNC. | 30 | P27544 | 350 | CERS1_HUMAN Ceramide synthase 1 OS=Homo sapie... | 145 | 0.000005 | 52.4 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; ISS:HGNC. | | | | | | | | | | GO:0050291; F:sphingosine N-acyltransferase activity; ISS:HGNC. | | | | | | | | | | GO:0046513; P:ceramide biosynthetic process; ISS:HGNC.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 31 | Q01685 | 374 | TRAM1_CANFA Translocating chain-associated me... | 123 | 0.0003 | 46.6 | 26 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | GO:0015031; P:protein transport; IEA:UniProtKB-KW. |
