rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q14847 | 261 | LASP1_HUMAN LIM and SH3 domain protein 1 OS=H... | 55 | 3.3 | 32.7 | 35 | 58 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 212 | Q99MZ8 | 263 | LASP1_RAT LIM and SH3 domain protein 1 OS=Rat... | 55 | 3.3 | 32.7 | 35 | 58 | GO:0030864; C:cortical actin cytoskeleton; IDA:UniProtKB. | | | | | | | | | | GO:0015075; F:ion transmembrane transporter activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 213 | P16885 | 1265 | PLCG2_HUMAN 1-phosphatidylinositol 4,5-bispho... | 65 | 3.4 | 33.1 | 37 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:UniProtKB. | | | | | | | | | | GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0050853; P:B cell receptor signaling pathway; ISS:UniProtKB.::GO:0019722; P:calcium-mediated signaling; NAS:UniProtKB.::GO:0006661; P:phosphatidylinositol biosynthetic process; IDA:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0051209; P:release of sequestered calcium ion into cytosol; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; TAS:UniProtKB. | 214 | Q5R5W0 | 261 | LASP1_PONAB LIM and SH3 domain protein 1 OS=P... | 55 | 3.5 | 32.7 | 35 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 215 | Q9JHL4 | 436 | DBNL_RAT Drebrin-like protein OS=Rattus norve... | 58 | 3.5 | 33.1 | 36 | 53 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB. | 216 | Q61792 | 263 | LASP1_MOUSE LIM and SH3 domain protein 1 OS=M... | 55 | 3.6 | 32.7 | 35 | 58 | GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 217 | P41239 | 450 | CSK_CHICK Tyrosine-protein kinase CSK OS=Gall... | 58 | 3.6 | 33.1 | 29 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC. | | | | | | | | | | | 218 | Q3B7M5 | 260 | LASP1_BOVIN LIM and SH3 domain protein 1 OS=B... | 55 | 3.7 | 32.7 | 35 | 58 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006811; P:ion transport; IEA:UniProtKB-KW. | 219 | Q5BBL4 | 581 | HSE1_EMENI Class E vacuolar protein-sorting m... | 57 | 3.8 | 33.1 | 33 | 54 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 220 | Q9JJS5 | 961 | SH3B4_RAT SH3 domain-binding protein 4 OS=Rat... | 60 | 3.8 | 33.1 | 35 | 50 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 221 | A6H7G2 | 423 | DBNL_BOVIN Drebrin-like protein OS=Bos taurus... | 58 | 3.9 | 32.7 | 36 | 53 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 222 | Q921I6 | 962 | SH3B4_MOUSE SH3 domain-binding protein 4 OS=M... | 60 | 3.9 | 33.1 | 35 | 50 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 223 | Q75JD4 | 533 | Y1676_DICDI SH3 and FCH domain-containing pro... | 55 | 3.9 | 32.7 | 38 | 58 | | | | | | | | | | | | | | | | | | | | | | 224 | Q62418 | 436 | DBNL_MOUSE Drebrin-like protein OS=Mus muscul... | 58 | 4 | 32.7 | 36 | 53 | GO:0005938; C:cell cortex; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; IDA:MGI. | 225 | Q6CHN0 | 1136 | SLA1_YARLI Actin cytoskeleton-regulatory comp... | 53 | 4.2 | 33.1 | 32 | 53 | GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 226 | Q9ES28 | 862 | ARHG7_MOUSE Rho guanine nucleotide exchange f... | 52 | 4.4 | 32.7 | 37 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. | 227 | Q08DK5 | 395 | SHLB2_BOVIN Endophilin-B2 OS=Bos taurus (Bovi... | 80 | 4.6 | 32.7 | 29 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 228 | Q6NRL2 | 550 | SNX33_XENLA Sorting nexin-33 OS=Xenopus laevi... | 55 | 4.8 | 32.7 | 35 | 65 | | | | | | | | | | | GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro. | 229 | O55043 | 646 | ARHG7_RAT Rho guanine nucleotide exchange fac... | 52 | 5 | 32.7 | 37 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:RGD.::GO:0030426; C:growth cone; IDA:RGD.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0043615; P:astrocyte cell migration; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IDA:RGD. | 230 | Q14155 | 803 | ARHG7_HUMAN Rho guanine nucleotide exchange f... | 52 | 5 | 32.7 | 37 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 231 | Q86WN1 | 690 | FCSD1_HUMAN FCH and double SH3 domains protei... | 57 | 5 | 32.7 | 32 | 54 | | | | | | | | | | | | | | | | | | | | | | 232 | P10569 | 1168 | MYSC_ACACA Myosin IC heavy chain OS=Acanthamo... | 57 | 5.3 | 32.7 | 30 | 61 | GO:0016459; C:myosin complex; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro. | | | | | | | | | | | 233 | Q9UJU6 | 430 | DBNL_HUMAN Drebrin-like protein OS=Homo sapie... | 58 | 5.3 | 32.3 | 36 | 53 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0008047; F:enzyme activator activity; TAS:ProtInc. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB. | 234 | Q6BNP6 | 512 | HSE1_DEBHA Class E vacuolar protein-sorting m... | 57 | 5.3 | 32.3 | 40 | 56 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 235 | P24604 | 630 | TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus ... | 53 | 5.4 | 32.3 | 32 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 236 | Q6PFY1 | 688 | FCSD1_MOUSE FCH and double SH3 domains protei... | 57 | 5.8 | 32.3 | 32 | 54 | | | | | | | | | | | | | | | | | | | | | | 237 | Q9NR46 | 395 | SHLB2_HUMAN Endophilin-B2 OS=Homo sapiens (Hu... | 80 | 5.9 | 32.3 | 28 | 49 | GO:0005737; C:cytoplasm; IDA:HGNC.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro. | | | | | | | | | | GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro. | 238 | Q6FN49 | 450 | HSE1_CANGA Class E vacuolar protein-sorting m... | 54 | 6.5 | 32.3 | 37 | 54 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 239 | A1CEK6 | 599 | HSE1_ASPCL Class E vacuolar protein-sorting m... | 57 | 7.2 | 32 | 33 | 54 | GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 240 | Q9P0V3 | 963 | SH3B4_HUMAN SH3 domain-binding protein 4 OS=H... | 60 | 7.4 | 32.3 | 35 | 48 | GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.::GO:0005905; C:coated pit; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW. | 241 | Q99JB8 | 424 | PACN3_MOUSE Protein kinase C and casein kinas... | 55 | 7.4 | 32 | 33 | 62 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008092; F:cytoskeletal protein binding; IDA:MGI. | | | | | | | | | | GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0045806; P:negative regulation of endocytosis; IDA:MGI. |