rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | Q54KE6 | 699 | MCCA_DICDI Methylcrotonoyl-CoA carboxylase su... | 310 | 4e-29 | 121 | 31 | 49 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; ISS:dictyBase. | | | | | | | | | | GO:0006552; P:leucine catabolic process; ISS:dictyBase. | 2 | Q96RQ3 | 725 | MCCA_HUMAN Methylcrotonoyl-CoA carboxylase su... | 302 | 3e-24 | 107 | 28 | 49 | GO:0005743; C:mitochondrial inner membrane; TAS:Reactome.::GO:0005759; C:mitochondrial matrix; NAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009374; F:biotin binding; NAS:UniProtKB.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; NAS:UniProtKB. | | | | | | | | | | GO:0006768; P:biotin metabolic process; NAS:UniProtKB.::GO:0006552; P:leucine catabolic process; NAS:UniProtKB. | 3 | Q99MR8 | 717 | MCCA_MOUSE Methylcrotonoyl-CoA carboxylase su... | 302 | 1e-22 | 102 | 28 | 47 | GO:0005743; C:mitochondrial inner membrane; IDA:MGI.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 4 | Q5I0C3 | 715 | MCCA_RAT Methylcrotonoyl-CoA carboxylase subu... | 302 | 7e-20 | 93.6 | 27 | 46 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 5 | Q2QMG2 | 737 | MCCA_ORYSJ Methylcrotonoyl-CoA carboxylase su... | 320 | 3e-17 | 85.9 | 26 | 45 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 6 | Q19842 | 724 | PCCA_CAEEL Propionyl-CoA carboxylase alpha ch... | 309 | 0.000000000002 | 70.9 | 28 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 7 | P14882 | 737 | PCCA_RAT Propionyl-CoA carboxylase alpha chai... | 302 | 0.000000000003 | 70.5 | 25 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; TAS:RGD. | | | | | | | | | | GO:0009063; P:cellular amino acid catabolic process; TAS:RGD.::GO:0009062; P:fatty acid catabolic process; TAS:RGD. | 8 | P05165 | 728 | PCCA_HUMAN Propionyl-CoA carboxylase alpha ch... | 300 | 0.000000000006 | 69.3 | 23 | 43 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; TAS:ProtInc. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; TAS:Reactome.::GO:0019626; P:short-chain fatty acid catabolic process; TAS:Reactome. | 9 | Q42777 | 731 | MCCA_SOYBN Methylcrotonoyl-CoA carboxylase su... | 64 | 0.0001 | 47 | 38 | 63 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 10 | O27939 | 491 | PYCA_METTH Pyruvate carboxylase subunit A OS=... | 69 | 0.00000000007 | 66.2 | 48 | 67 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 11 | Q06862 | 447 | ACCC_NOSS1 Biotin carboxylase OS=Nostoc sp. (... | 58 | 0.0000000002 | 64.7 | 52 | 69 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 12 | Q612F5 | 738 | PCCA_CAEBR Propionyl-CoA carboxylase alpha ch... | 307 | 0.0000000004 | 63.9 | 25 | 43 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IEA:EC. | | | | | | | | | | | 13 | P0A508 | 654 | BCCA_MYCTU Acetyl-/propionyl-coenzyme A carbo... | 300 | 0.0000000005 | 63.5 | 26 | 41 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 14 | P0A509 | 654 | BCCA_MYCBO Acetyl-/propionyl-coenzyme A carbo... | 300 | 0.0000000005 | 63.5 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 15 | Q05920 | 1178 | PYC_MOUSE Pyruvate carboxylase, mitochondrial... | 72 | 0.000002 | 53.1 | 39 | 58 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 16 | Q42523 | 734 | MCCA_ARATH Methylcrotonoyl-CoA carboxylase su... | 64 | 0.0002 | 46.6 | 36 | 63 | GO:0022626; C:cytosolic ribosome; IDA:TAIR.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0050897; F:cobalt ion binding; IDA:TAIR.::GO:0004485; F:methylcrotonoyl-CoA carboxylase activity; IDA:TAIR. | | | | | | | | | | GO:0006552; P:leucine catabolic process; IDA:TAIR. | 17 | Q58626 | 501 | PYCA_METJA Pyruvate carboxylase subunit A OS=... | 64 | 0.00000001 | 59.7 | 44 | 64 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 18 | P52873 | 1178 | PYC_RAT Pyruvate carboxylase, mitochondrial O... | 72 | 0.000003 | 52.4 | 39 | 58 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:RGD.::GO:0009374; F:biotin binding; IMP:RGD.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IDA:RGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IDA:RGD.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW.::GO:0006107; P:oxaloacetate metabolic process; IDA:RGD.::GO:0006090; P:pyruvate metabolic process; IDA:RGD. | 19 | Q29RK2 | 1178 | PYC_BOVIN Pyruvate carboxylase, mitochondrial... | 72 | 0.000001 | 53.5 | 39 | 58 | GO:0005743; C:mitochondrial inner membrane; ISS:AgBase.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 20 | O17732 | 1175 | PYC1_CAEEL Pyruvate carboxylase 1 OS=Caenorha... | 62 | 0.00008 | 47.8 | 34 | 58 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 21 | P11498 | 1178 | PYC_HUMAN Pyruvate carboxylase, mitochondrial... | 72 | 0.000002 | 53.1 | 39 | 58 | GO:0005759; C:mitochondrial matrix; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0009374; F:biotin binding; TAS:ProtInc.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; TAS:Reactome. | | | | | | | | | | GO:0006094; P:gluconeogenesis; TAS:Reactome.::GO:0008610; P:lipid biosynthetic process; IEA:UniProtKB-KW. | 22 | Q9ZAA7 | 145 | GCDC_ACIFV Glutaconyl-CoA decarboxylase subun... | 70 | 0.00000007 | 54.3 | 39 | 60 | | | | | | | | | | | GO:0018801; F:glutaconyl-CoA decarboxylase activity; IEA:EC. | | | | | | | | | | GO:0006814; P:sodium ion transport; IEA:UniProtKB-KW. | 23 | O34544 | 444 | ACCC2_BACSU Biotin carboxylase 2 OS=Bacillus ... | 60 | 0.0000001 | 56.2 | 43 | 67 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 24 | Q91ZA3 | 724 | PCCA_MOUSE Propionyl-CoA carboxylase alpha ch... | 73 | 0.0002 | 46.6 | 33 | 59 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0004658; F:propionyl-CoA carboxylase activity; IMP:MGI. | | | | | | | | | | | 25 | Q9KDS9 | 452 | ACCC_BACHD Biotin carboxylase OS=9153 / C-125... | 57 | 0.0000005 | 54.3 | 44 | 65 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 26 | P49787 | 450 | ACCC1_BACSU Biotin carboxylase 1 OS=Bacillus ... | 60 | 0.000001 | 53.5 | 42 | 63 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 27 | Q9UUE1 | 1185 | PYC_SCHPO Pyruvate carboxylase OS=Schizosacch... | 58 | 0.021 | 40 | 36 | 53 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; ISS:PomBase. | | | | | | | | | | GO:0006091; P:generation of precursor metabolites and energy; NAS:PomBase.::GO:0006094; P:gluconeogenesis; ISS:PomBase. | 28 | O30019 | 506 | PYCA_ARCFU Pyruvate carboxylase subunit A OS=... | 58 | 0.000002 | 52.4 | 47 | 64 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004736; F:pyruvate carboxylase activity; IEA:EC. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IEA:UniProtKB-KW. | 29 | D3DJ41 | 652 | 2OCL_HYDTT 2-oxoglutarate carboxylase large s... | 69 | 0.000002 | 52.4 | 39 | 62 | | | | | | | | | | | GO:0034029; F:2-oxoglutarate carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 30 | P11154 | 1178 | PYC1_YEAST Pyruvate carboxylase 1 OS=Saccharo... | 58 | 0.001 | 44.3 | 40 | 53 | GO:0005829; C:cytosol; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004736; F:pyruvate carboxylase activity; IMP:SGD. | | | | | | | | | | GO:0006094; P:gluconeogenesis; IMP:SGD. | 31 | O52058 | 449 | ACCC_ALLVD Biotin carboxylase OS=(Chromatium ... | 60 | 0.000004 | 51.6 | 40 | 63 | | | | | | | | | | | GO:0003989; F:acetyl-CoA carboxylase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004075; F:biotin carboxylase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. |