| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | P54736 | 830 | PKN2_MYXXA Serine/threonine-protein kinase pk... | 132 | 0.011 | 43.9 | 26 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 392 | Q9QY01 | 1037 | ULK2_MOUSE Serine/threonine-protein kinase UL... | 154 | 0.00000000005 | 71.2 | 29 | 48 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0048675; P:axon extension; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010506; P:regulation of autophagy; IMP:UniProtKB.::GO:0042594; P:response to starvation; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 393 | O14047 | 312 | PPK11_SCHPO Serine/threonine-protein kinase p... | 243 | 0.00000002 | 61.2 | 26 | 40 | GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051519; P:activation of bipolar cell growth; IMP:PomBase. | 394 | P45894 | 589 | AAPK1_CAEEL 5'-AMP-activated protein kinase c... | 169 | 0.001 | 47.4 | 24 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase. | 395 | Q8IW41 | 473 | MAPK5_HUMAN MAP kinase-activated protein kina... | 139 | 0.14 | 40 | 24 | 38 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004708; F:MAP kinase kinase activity; TAS:ProtInc.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0032007; P:negative regulation of TOR signaling cascade; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IDA:UniProtKB.::GO:0090400; P:stress-induced premature senescence; IDA:UniProtKB. | 396 | Q9JI10 | 497 | STK3_MOUSE Serine/threonine-protein kinase 3 ... | 63 | 0.001 | 47 | 33 | 62 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0060706; P:cell differentiation involved in embryonic placenta development; IGI:MGI.::GO:0007417; P:central nervous system development; IGI:MGI.::GO:0003157; P:endocardium development; IGI:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IGI:MGI.::GO:0046621; P:negative regulation of organ growth; IGI:MGI.::GO:0001841; P:neural tube formation; IGI:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0060215; P:primitive hemopoiesis; IGI:MGI. | 397 | A8X6H4 | 344 | CMK1_CAEBR Calcium/calmodulin-dependent prote... | 226 | 0.000001 | 55.8 | 26 | 45 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 398 | Q9S9V0 | 484 | CDPKV_ARATH Calcium-dependent protein kinase ... | 203 | 0.00000000003 | 71.2 | 28 | 49 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009751; P:response to salicylic acid stimulus; IEP:TAIR. | 399 | Q03407 | 766 | PKH1_YEAST Serine/threonine-protein kinase PK... | 143 | 0.007 | 44.7 | 23 | 45 | GO:0005829; C:cytosol; IDA:SGD.::GO:0032126; C:eisosome; IDA:SGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD. | 400 | Q9V3Q6 | 678 | M3K7_DROME Mitogen-activated protein kinase k... | 178 | 0.000008 | 54.3 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004706; F:JUN kinase kinase kinase activity; IMP:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IGI:FlyBase.::GO:0071222; P:cellular response to lipopolysaccharide; IMP:FlyBase.::GO:0050829; P:defense response to Gram-negative bacterium; IMP:FlyBase.::GO:0051607; P:defense response to virus; IMP:FlyBase.::GO:0007391; P:dorsal closure; IMP:FlyBase.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0048802; P:notum morphogenesis; IMP:FlyBase.::GO:0016318; P:ommatidial rotation; IMP:FlyBase.::GO:0006963; P:positive regulation of antibacterial peptide biosynthetic process; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IMP:FlyBase. | 401 | Q6IP06 | 493 | STK3_XENLA Serine/threonine-protein kinase 3 ... | 63 | 0.015 | 43.1 | 32 | 60 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB. | 402 | Q8BPM2 | 847 | M4K5_MOUSE Mitogen-activated protein kinase k... | 61 | 0.004 | 45.4 | 33 | 59 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB. | 403 | Q38773 | 280 | CDC2B_ANTMA Cell division control protein 2 h... | 107 | 0.0003 | 48.1 | 28 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 404 | P27704 | 720 | MK06_RAT Mitogen-activated protein kinase 6 O... | 172 | 0.0005 | 48.5 | 22 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 405 | Q802A6 | 491 | STK4_SQUAC Serine/threonine-protein kinase 3/... | 63 | 0.0009 | 47.4 | 33 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 406 | Q61532 | 720 | MK06_MOUSE Mitogen-activated protein kinase 6... | 172 | 0.0005 | 48.1 | 22 | 47 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IDA:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 407 | Q9C9U4 | 576 | MPK15_ARATH Mitogen-activated protein kinase ... | 121 | 0.00002 | 53.1 | 24 | 46 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 408 | Q9NB31 | 497 | CST1_CAEEL Serine/threonine-protein kinase cs... | 62 | 0.035 | 42 | 34 | 58 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0008340; P:determination of adult lifespan; IMP:UniProtKB.::GO:0048747; P:muscle fiber development; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 409 | Q61035 | 509 | SYHC_MOUSE Histidine--tRNA ligase, cytoplasmi... | 305 | 0.00000000004 | 71.2 | 26 | 44 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004821; F:histidine-tRNA ligase activity; IEA:EC. | | | | | | | | | | GO:0006427; P:histidyl-tRNA aminoacylation; IEA:InterPro. | 410 | Q9Y4K4 | 846 | M4K5_HUMAN Mitogen-activated protein kinase k... | 61 | 0.004 | 45.4 | 33 | 59 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005083; F:small GTPase regulator activity; IEA:InterPro. | | | | | | | | | | GO:0007257; P:activation of JUN kinase activity; TAS:ProtInc. | 411 | A1A5Q6 | 654 | SMK_RAT Sperm motility kinase OS=Rattus norve... | 243 | 0.015 | 43.5 | 20 | 40 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 412 | Q8IYT8 | 1036 | ULK2_HUMAN Serine/threonine-protein kinase UL... | 178 | 0.00000000004 | 71.6 | 28 | 44 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:0042594; P:response to starvation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 413 | Q61846 | 643 | MELK_MOUSE Maternal embryonic leucine zipper ... | 202 | 0.00000000004 | 71.2 | 30 | 46 | GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; ISS:UniProtKB.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.::GO:0061351; P:neural precursor cell proliferation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB. | 414 | O18209 | 677 | PMY13_CAEEL Membrane-associated tyrosine- and... | 214 | 0.0002 | 49.7 | 25 | 44 | GO:0019898; C:extrinsic to membrane; TAS:UniProtKB.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB. | | | | | | | | | | GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0019915; P:lipid storage; IMP:WormBase.::GO:0051327; P:M phase of meiotic cell cycle; IMP:UniProtKB.::GO:0051447; P:negative regulation of meiotic cell cycle; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:UniProtKB.::GO:0001556; P:oocyte maturation; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW. | 415 | Q55GC2 | 1142 | DST2_DICDI Serine/threonine-protein kinase ds... | 195 | 0.000003 | 55.8 | 26 | 41 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006950; P:response to stress; ISS:dictyBase. | 416 | Q16659 | 721 | MK06_HUMAN Mitogen-activated protein kinase 6... | 172 | 0.0008 | 47.8 | 22 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 417 | Q3U214 | 1321 | MAST3_MOUSE Microtubule-associated serine/thr... | 275 | 0.00007 | 51.2 | 22 | 39 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 418 | A4K2M3 | 487 | STK4_PAPAN Serine/threonine-protein kinase 4 ... | 63 | 0.002 | 46.2 | 32 | 62 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB. | 419 | Q5R7U1 | 721 | MK06_PONAB Mitogen-activated protein kinase 6... | 172 | 0.0008 | 47.8 | 22 | 47 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 420 | Q53N72 | 498 | MPK15_ORYSJ Mitogen-activated protein kinase ... | 121 | 0.000002 | 55.8 | 25 | 47 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004707; F:MAP kinase activity; IEA:EC. | | | | | | | | | | | 421 | Q04759 | 706 | KPCT_HUMAN Protein kinase C theta type OS=Hom... | 170 | 0.00004 | 52 | 26 | 42 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; ISS:BHF-UCL.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; IMP:UniProtKB.::GO:0070233; P:negative regulation of T cell apoptotic process; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032740; P:positive regulation of interleukin-17 production; ISS:UniProtKB.::GO:0032753; P:positive regulation of interleukin-4 production; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:2000318; P:positive regulation of T-helper 17 type immune response; ISS:UniProtKB.::GO:2000570; P:positive regulation of T-helper 2 cell activation; ISS:UniProtKB.::GO:0001558; P:regulation of cell growth; NAS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome. |
