rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
31 | Q9V5L3 | 589 | C49A1_DROME Probable cytochrome P450 49a1 OS=... | 213 | 0.00000008 | 58.5 | 25 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 32 | Q9LTM3 | 502 | C71BK_ARATH Cytochrome P450 71B20 OS=Arabidop... | 379 | 0.0000001 | 58.2 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 33 | Q64581 | 497 | CP3AI_RAT Cytochrome P450 3A18 OS=Rattus norv... | 275 | 0.0000001 | 57.4 | 23 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008390; F:testosterone 16-alpha-hydroxylase activity; IDA:RGD.::GO:0050649; F:testosterone 6-beta-hydroxylase activity; IDA:RGD. | | | | | | | | | | | 34 | Q8SPK1 | 504 | CP4AO_PIG Cytochrome P450 4A24 OS=Sus scrofa ... | 187 | 0.0000002 | 57.4 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 35 | P24464 | 508 | CP4AC_RAT Cytochrome P450 4A12 OS=Rattus norv... | 206 | 0.0000002 | 57 | 26 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IDA:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD. | 36 | O18993 | 503 | CP3AL_CALJA Cytochrome P450 3A21 OS=Callithri... | 223 | 0.0000002 | 57 | 24 | 40 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 37 | P50859 | 533 | CP51_CANGA Lanosterol 14-alpha demethylase OS... | 217 | 0.0000003 | 57 | 25 | 42 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 38 | P58048 | 506 | C71B8_ARATH Cytochrome P450 71B8 OS=Arabidops... | 225 | 0.0000003 | 56.6 | 22 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 39 | Q6XQ14 | 511 | C71E7_MANES 2-methylbutanal oxime monooxygena... | 354 | 0.0000004 | 56.2 | 19 | 40 | GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016709; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen; IEA:EC. | | | | | | | | | | | 40 | Q9V4U7 | 509 | C6A14_DROME Probable cytochrome P450 6a14 OS=... | 232 | 0.0000004 | 56.2 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 41 | P24463 | 503 | CP3AC_CANFA Cytochrome P450 3A12 OS=Canis fam... | 224 | 0.0000004 | 56.2 | 25 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 42 | Q42797 | 506 | TCMO_SOYBN Trans-cinnamate 4-monooxygenase OS... | 219 | 0.0000004 | 56.2 | 26 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:EC. | | | | | | | | | | | 43 | Q8SPK0 | 504 | CP4AP_PIG Cytochrome P450 4A25 OS=Sus scrofa ... | 187 | 0.0000004 | 56.2 | 26 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 44 | O81973 | 510 | C93A3_SOYBN Cytochrome P450 93A3 OS=Glycine m... | 338 | 0.0000004 | 56.2 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 45 | O23365 | 580 | C97B3_ARATH Cytochrome P450 97B3, chloroplast... | 241 | 0.0000005 | 56.2 | 25 | 40 | GO:0031969; C:chloroplast membrane; IEA:UniProtKB-SubCell.::GO:0009570; C:chloroplast stroma; IDA:TAIR. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | GO:0016117; P:carotenoid biosynthetic process; IEA:UniProtKB-KW. | 46 | Q60991 | 507 | CP7B1_MOUSE 25-hydroxycholesterol 7-alpha-hyd... | 215 | 0.0000005 | 55.8 | 26 | 44 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0033783; F:25-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0007586; P:digestion; TAS:UniProtKB.::GO:0033147; P:negative regulation of intracellular estrogen receptor signaling pathway; IMP:MGI.::GO:0050679; P:positive regulation of epithelial cell proliferation; IMP:MGI.::GO:0060740; P:prostate gland epithelium morphogenesis; IMP:MGI. | 47 | Q9LIP6 | 500 | C71BV_ARATH Cytochrome P450 71B34 OS=Arabidop... | 373 | 0.0000006 | 55.5 | 23 | 39 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 48 | Q07217 | 514 | CP11A_ONCMY Cholesterol side-chain cleavage e... | 191 | 0.0000006 | 55.5 | 25 | 40 | GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008386; F:cholesterol monooxygenase (side-chain-cleaving) activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0008203; P:cholesterol metabolic process; IEA:UniProtKB-KW.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 49 | P49602 | 561 | CP51_USTMA Lanosterol 14-alpha demethylase OS... | 393 | 0.0000006 | 55.5 | 23 | 39 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008398; F:sterol 14-demethylase activity; IEA:EC. | | | | | | | | | | GO:0016126; P:sterol biosynthetic process; IEA:UniProtKB-KW. | 50 | Q9NYL5 | 469 | CP39A_HUMAN 24-hydroxycholesterol 7-alpha-hyd... | 248 | 0.0000007 | 55.5 | 23 | 40 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005792; C:microsome; TAS:UniProtKB. | | | | | | | | | | GO:0033782; F:24-hydroxycholesterol 7alpha-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006699; P:bile acid biosynthetic process; IDA:UniProtKB.::GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW.::GO:0007586; P:digestion; TAS:UniProtKB.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 51 | O35728 | 507 | CP4AE_MOUSE Cytochrome P450 4A14 OS=Mus muscu... | 187 | 0.0000007 | 55.5 | 27 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IEA:EC.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 52 | Q64481 | 504 | CP3AG_MOUSE Cytochrome P450 3A16 OS=Mus muscu... | 223 | 0.0000008 | 55.5 | 21 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | | 53 | O64636 | 512 | C76C1_ARATH Cytochrome P450 76C1 OS=Arabidops... | 274 | 0.000001 | 55.1 | 24 | 40 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 54 | P63719 | 430 | CP139_MYCTU Putative cytochrome P450 139 OS=M... | 272 | 0.000001 | 54.7 | 25 | 40 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 55 | P63720 | 430 | CP139_MYCBO Putative cytochrome P450 139 OS=M... | 272 | 0.000001 | 54.7 | 25 | 40 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 56 | O15528 | 508 | CP27B_HUMAN 25-hydroxyvitamin D-1 alpha hydro... | 231 | 0.000001 | 54.7 | 26 | 40 | GO:0005741; C:mitochondrial outer membrane; TAS:Reactome. | | | | | | | | | | GO:0004498; F:calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0030282; P:bone mineralization; IEP:BHF-UCL.::GO:0055074; P:calcium ion homeostasis; IMP:BHF-UCL.::GO:0006816; P:calcium ion transport; ISS:BHF-UCL.::GO:0046697; P:decidualization; IEP:BHF-UCL.::GO:0070314; P:G1 to G0 transition; IMP:BHF-UCL.::GO:0010956; P:negative regulation of calcidiol 1-monooxygenase activity; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IMP:BHF-UCL.::GO:0008285; P:negative regulation of cell proliferation; IDA:BHF-UCL.::GO:0045618; P:positive regulation of keratinocyte differentiation; IMP:BHF-UCL.::GO:0010980; P:positive regulation of vitamin D 24-hydroxylase activity; IDA:BHF-UCL.::GO:0070564; P:positive regulation of vitamin D receptor signaling pathway; IDA:BHF-UCL.::GO:0030500; P:regulation of bone mineralization; IMP:BHF-UCL.::GO:0043627; P:response to estrogen stimulus; IEP:BHF-UCL.::GO:0034341; P:response to interferon-gamma; IDA:BHF-UCL.::GO:0032496; P:response to lipopolysaccharide; IEP:BHF-UCL.::GO:0034612; P:response to tumor necrosis factor; IEP:BHF-UCL.::GO:0033280; P:response to vitamin D; IEP:BHF-UCL.::GO:0042368; P:vitamin D biosynthetic process; IDA:BHF-UCL.::GO:0006805; P:xenobiotic metabolic process; TAS:Reactome. | 57 | Q91WL5 | 508 | CP4CA_MOUSE Cytochrome P450 4A12A OS=Mus musc... | 214 | 0.000001 | 54.7 | 25 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IDA:MGI.::GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB. | 58 | Q64464 | 503 | CP3AD_MOUSE Cytochrome P450 3A13 OS=Mus muscu... | 224 | 0.000001 | 54.7 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0070330; F:aromatase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0010628; P:positive regulation of gene expression; IMP:MGI. | 59 | P20817 | 507 | CP4AE_RAT Cytochrome P450 4A14 OS=Rattus norv... | 227 | 0.000001 | 54.7 | 26 | 39 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:RGD. | | | | | | | | | | GO:0018685; F:alkane 1-monooxygenase activity; IMP:RGD.::GO:0008391; F:arachidonic acid monooxygenase activity; IMP:RGD.::GO:0052869; F:arachidonic acid omega-hydroxylase activity; IEA:EC.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro. | | | | | | | | | | GO:0019369; P:arachidonic acid metabolic process; IMP:RGD.::GO:0046456; P:icosanoid biosynthetic process; IMP:RGD.::GO:0001822; P:kidney development; IEP:RGD.::GO:0048252; P:lauric acid metabolic process; IDA:RGD.::GO:0043651; P:linoleic acid metabolic process; IDA:RGD. | 60 | Q96514 | 504 | C71B7_ARATH Cytochrome P450 71B7 OS=Arabidops... | 359 | 0.000001 | 54.3 | 21 | 37 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0016705; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen; IEA:InterPro. | | | | | | | | | | | 61 | P48522 | 505 | TCMO_CATRO Trans-cinnamate 4-monooxygenase OS... | 211 | 0.000001 | 54.3 | 26 | 43 | | | | | | | | | | | GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0020037; F:heme binding; IEA:InterPro.::GO:0016710; F:trans-cinnamate 4-monooxygenase activity; IEA:EC. | | | | | | | | | | |