rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
391 | Q99J47 | 323 | DRS7B_MOUSE Dehydrogenase/reductase SDR famil... | 132 | 0.072 | 37.7 | 33 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 392 | O74628 | 292 | YQ53_SCHPO Uncharacterized oxidoreductase C16... | 121 | 0.073 | 37.7 | 25 | 41 | GO:0005829; C:cytosol; IDA:PomBase. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 393 | Q92781 | 318 | RDH1_HUMAN 11-cis retinol dehydrogenase OS=Ho... | 117 | 0.073 | 37.7 | 29 | 44 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0007601; P:visual perception; TAS:ProtInc. | 394 | P16152 | 277 | CBR1_HUMAN Carbonyl reductase [NADPH] 1 OS=Ho... | 35 | 0.079 | 37.7 | 46 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; IDA:UniProtKB.::GO:0042373; P:vitamin K metabolic process; IDA:UniProtKB. | 395 | Q5RCU5 | 277 | CBR1_PONAB Carbonyl reductase [NADPH] 1 OS=Po... | 35 | 0.082 | 37.7 | 46 | 63 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 396 | P69936 | 248 | YDFG_SALTY NADP-dependent L-serine/L-allo-thr... | 126 | 0.093 | 37.4 | 23 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 397 | P69935 | 248 | YDFG_SALTI NADP-dependent L-serine/L-allo-thr... | 126 | 0.093 | 37.4 | 23 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 398 | Q9Y140 | 326 | DHRS7_DROME Dehydrogenase/reductase SDR famil... | 123 | 0.11 | 37.4 | 27 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 399 | Q5F389 | 414 | WWOX_CHICK WW domain-containing oxidoreductas... | 136 | 0.11 | 37.4 | 28 | 43 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 400 | Q3U0B3 | 260 | DHR11_MOUSE Dehydrogenase/reductase SDR famil... | 155 | 0.11 | 37 | 26 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 401 | O75828 | 277 | CBR3_HUMAN Carbonyl reductase [NADPH] 3 OS=Ho... | 99 | 0.11 | 37 | 29 | 44 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0070402; F:NADPH binding; IDA:UniProtKB. | | | | | | | | | | | 402 | O07399 | 255 | FABG_MYCAV 3-oxoacyl-[acyl-carrier-protein] r... | 60 | 0.12 | 37 | 33 | 53 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; ISS:UniProtKB.::GO:0050661; F:NADP binding; ISS:UniProtKB. | | | | | | | | | | GO:0030497; P:fatty acid elongation; ISS:UniProtKB.] | 403 | P47227 | 277 | BPHB_BURXL Cis-2,3-dihydrobiphenyl-2,3-diol d... | 135 | 0.13 | 37 | 29 | 43 | | | | | | | | | | | GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 404 | Q5ZJG8 | 331 | HSDL1_CHICK Hydroxysteroid dehydrogenase-like... | 105 | 0.13 | 37 | 30 | 46 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 405 | P73826 | 240 | FABG2_SYNY3 3-oxoacyl-[acyl-carrier-protein] ... | 259 | 0.13 | 37 | 24 | 39 | | | | | | | | | | | GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.] | 406 | Q6R0J2 | 292 | DHI1_MESAU Corticosteroid 11-beta-dehydrogena... | 123 | 0.13 | 37 | 27 | 45 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW. | 407 | P16232 | 288 | DHI1_RAT Corticosteroid 11-beta-dehydrogenase... | 127 | 0.14 | 37 | 30 | 46 | GO:0045177; C:apical part of cell; IDA:RGD.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD. | | | | | | | | | | GO:0070524; F:11-beta-hydroxysteroid dehydrogenase (NADP+) activity; IEA:EC.::GO:0003845; F:11-beta-hydroxysteroid dehydrogenase [NAD(P) activity; IDA:RGD.::GO:0050661; F:NADP binding; IDA:RGD.::GO:0005496; F:steroid binding; IPI:RGD. | | | | | | | | | | GO:0071392; P:cellular response to estradiol stimulus; IEP:RGD.::GO:0006704; P:glucocorticoid biosynthetic process; IDA:RGD.::GO:0006713; P:glucocorticoid catabolic process; IDA:RGD.::GO:0018963; P:phthalate metabolic process; IEP:RGD.::GO:0043456; P:regulation of pentose-phosphate shunt; IDA:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.] | 408 | Q28IU1 | 320 | DHB12_XENTR Estradiol 17-beta-dehydrogenase 1... | 125 | 0.14 | 37 | 25 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 409 | O00058 | 256 | MTDH_UROFA Probable NADP-dependent mannitol d... | 256 | 0.15 | 36.6 | 20 | 38 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 410 | P50167 | 278 | ARDH_PICST D-arabinitol 2-dehydrogenase [ribu... | 276 | 0.15 | 36.6 | 22 | 41 | | | | | | | | | | | GO:0047038; F:D-arabinitol 2-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0005975; P:carbohydrate metabolic process; ISS:UniProtKB. | 411 | Q5R7K0 | 330 | HSDL1_PONAB Inactive hydroxysteroid dehydroge... | 127 | 0.16 | 37 | 30 | 45 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 412 | P39577 | 252 | DLTE_BACSU Uncharacterized oxidoreductase dlt... | 94 | 0.16 | 36.6 | 28 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 413 | P72220 | 277 | BPHB_PSEPU Cis-2,3-dihydrobiphenyl-2,3-diol d... | 128 | 0.16 | 36.6 | 29 | 45 | | | | | | | | | | | GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 414 | Q6UWP2 | 260 | DHR11_HUMAN Dehydrogenase/reductase SDR famil... | 98 | 0.19 | 36.2 | 31 | 49 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 415 | A5PJF6 | 330 | HSDL1_BOVIN Inactive hydroxysteroid dehydroge... | 105 | 0.25 | 36.2 | 31 | 47 | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro. | | | | | | | | | | | 416 | P18297 | 262 | SPRE_RAT Sepiapterin reductase OS=Rattus norv... | 121 | 0.26 | 35.8 | 33 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004757; F:sepiapterin reductase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010033; P:response to organic substance; IMP:RGD.::GO:0006729; P:tetrahydrobiopterin biosynthetic process; IMP:RGD. | 417 | Q4JK73 | 300 | DHB11_MACFA Estradiol 17-beta-dehydrogenase 1... | 123 | 0.26 | 36.2 | 23 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 418 | Q5NVG2 | 300 | DHB11_PONAB Estradiol 17-beta-dehydrogenase 1... | 128 | 0.27 | 36.2 | 22 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 419 | Q8NBQ5 | 300 | DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1... | 128 | 0.29 | 35.8 | 22 | 40 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 420 | P47844 | 277 | CBR1_RABIT Carbonyl reductase [NADPH] 1 OS=Or... | 126 | 0.29 | 35.8 | 29 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047021; F:15-hydroxyprostaglandin dehydrogenase (NADP+) activity; IEA:EC.::GO:0004090; F:carbonyl reductase (NADPH) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050221; F:prostaglandin-E2 9-reductase activity; IEA:EC. | | | | | | | | | | GO:0017144; P:drug metabolic process; ISS:UniProtKB.::GO:0042373; P:vitamin K metabolic process; ISS:UniProtKB. | 421 | A4IGM4 | 286 | DHI1L_XENTR Hydroxysteroid 11-beta-dehydrogen... | 99 | 0.37 | 35.4 | 32 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | |