| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | P20724 | 378 | ELYA_BACYA Alkaline elastase YaB OS=Bacillus ... | 163 | 0.00002 | 50.8 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 62 | P16519 | 638 | NEC2_HUMAN Neuroendocrine convertase 2 OS=Hom... | 96 | 0.00002 | 51.2 | 36 | 53 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0016020; C:membrane; IDA:BHF-UCL.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0005625; C:soluble fraction; IDA:BHF-UCL.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0034230; P:enkephalin processing; ISS:BHF-UCL.::GO:0030070; P:insulin processing; IDA:BHF-UCL.::GO:0034231; P:islet amyloid polypeptide processing; ISS:BHF-UCL.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 63 | Q5REC2 | 638 | NEC2_PONAB Neuroendocrine convertase 2 OS=Pon... | 96 | 0.00002 | 51.2 | 36 | 53 | GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 64 | P28841 | 637 | NEC2_RAT Neuroendocrine convertase 2 OS=Rattu... | 95 | 0.00003 | 50.8 | 37 | 52 | GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0004252; F:serine-type endopeptidase activity; IMP:BHF-UCL. | | | | | | | | | | GO:0034231; P:islet amyloid polypeptide processing; IMP:BHF-UCL.::GO:0006508; P:proteolysis; IMP:RGD. | 65 | Q03333 | 638 | NEC2_PIG Neuroendocrine convertase 2 OS=Sus s... | 96 | 0.00003 | 50.4 | 36 | 52 | GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 66 | P31339 | 621 | ASPA_AERSA Microbial serine proteinase OS=Aer... | 99 | 0.00003 | 50.4 | 38 | 47 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 67 | P21661 | 637 | NEC2_MOUSE Neuroendocrine convertase 2 OS=Mus... | 95 | 0.00003 | 50.4 | 37 | 52 | GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0034230; P:enkephalin processing; IDA:BHF-UCL.::GO:0007399; P:nervous system development; IEP:HGNC.::GO:0016540; P:protein autoprocessing; IDA:HGNC.::GO:0006508; P:proteolysis; IMP:MGI. | 68 | P08594 | 513 | AQL1_THEAQ Aqualysin-1 OS=Thermus aquaticus. ... | 104 | 0.00004 | 50.1 | 31 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 69 | A1XIH3 | 401 | SUB7_TRIEQ Subtilisin-like protease 7 OS=Tric... | 185 | 0.00004 | 50.1 | 29 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 70 | P29120 | 753 | NEC1_HUMAN Neuroendocrine convertase 1 OS=Hom... | 123 | 0.00004 | 50.1 | 32 | 49 | GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005794; C:Golgi apparatus; IBA:RefGenome.::GO:0030141; C:secretory granule; TAS:Reactome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:BHF-UCL. | | | | | | | | | | GO:0007267; P:cell-cell signaling; TAS:ProtInc.::GO:0034641; P:cellular nitrogen compound metabolic process; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0043043; P:peptide biosynthetic process; ISS:BHF-UCL.::GO:0016486; P:peptide hormone processing; TAS:Reactome.::GO:0006508; P:proteolysis; TAS:ProtInc.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome. | 71 | P28840 | 752 | NEC1_RAT Neuroendocrine convertase 1 OS=Rattu... | 123 | 0.00005 | 50.1 | 32 | 49 | GO:0043679; C:axon terminus; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005615; C:extracellular space; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0005791; C:rough endoplasmic reticulum; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0005802; C:trans-Golgi network; IDA:RGD.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0051087; F:chaperone binding; IPI:RGD.::GO:0043559; F:insulin binding; IPI:RGD.::GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0009790; P:embryo development; IEP:RGD.::GO:0022008; P:neurogenesis; IEP:RGD.::GO:0031016; P:pancreas development; IEP:RGD.::GO:0016486; P:peptide hormone processing; IDA:RGD.::GO:0021983; P:pituitary gland development; IEP:RGD.::GO:0050714; P:positive regulation of protein secretion; IDA:RGD.::GO:0016540; P:protein autoprocessing; IMP:RGD.::GO:0006508; P:proteolysis; IMP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0051592; P:response to calcium ion; IEP:RGD.::GO:0010157; P:response to chlorate; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0070542; P:response to fatty acid; IEP:RGD.::GO:0051384; P:response to glucocorticoid stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0070555; P:response to interleukin-1; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0043278; P:response to morphine; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0043434; P:response to peptide hormone stimulus; IEP:RGD. | 72 | C5PFR5 | 400 | SU11B_COCP7 Subtilisin-like protease CPC735_0... | 188 | 0.0001 | 48.5 | 26 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 73 | P30432 | 1679 | FUR2_DROME Furin-like protease 2 OS=Drosophil... | 109 | 0.0001 | 49.3 | 33 | 52 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IDA:FlyBase.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IEA:InterPro. | 74 | P29122 | 969 | PCSK6_HUMAN Proprotein convertase subtilisin/... | 101 | 0.0001 | 48.9 | 32 | 50 | GO:0009986; C:cell surface; IDA:BHF-UCL.::GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031012; C:extracellular matrix; IDA:BHF-UCL.::GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005796; C:Golgi lumen; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005625; C:soluble fraction; IDA:BHF-UCL. | | | | | | | | | | GO:0043499; F:eukaryotic cell surface binding; IDA:BHF-UCL.::GO:0008201; F:heparin binding; IDA:BHF-UCL.::GO:0048406; F:nerve growth factor binding; IDA:BHF-UCL.::GO:0004252; F:serine-type endopeptidase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0009100; P:glycoprotein metabolic process; IDA:BHF-UCL.::GO:0032455; P:nerve growth factor processing; TAS:Reactome.::GO:0032902; P:nerve growth factor production; IDA:BHF-UCL.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0030510; P:regulation of BMP signaling pathway; TAS:BHF-UCL.::GO:0032940; P:secretion by cell; IDA:BHF-UCL. | 75 | C5FJA5 | 400 | SUB7_ARTOC Subtilisin-like protease 7 OS=cani... | 183 | 0.0001 | 48.5 | 31 | 48 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 76 | Q9GLR0 | 638 | NEC2_BOVIN Neuroendocrine convertase 2 OS=Bos... | 95 | 0.0001 | 48.9 | 35 | 51 | GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0007399; P:nervous system development; ISS:AgBase.::GO:0016486; P:peptide hormone processing; ISS:AgBase.::GO:0016540; P:protein autoprocessing; ISS:AgBase.::GO:0006508; P:proteolysis; ISS:AgBase. | 77 | Q63415 | 937 | PCSK6_RAT Proprotein convertase subtilisin/ke... | 101 | 0.0001 | 48.9 | 32 | 50 | GO:0005615; C:extracellular space; IBA:RefGenome.::GO:0005794; C:Golgi apparatus; IBA:RefGenome. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0016486; P:peptide hormone processing; IEP:RGD.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 78 | Q64K36 | 400 | SUB7_ARTBE Subtilisin-like protease 7 OS=Arth... | 194 | 0.0001 | 48.1 | 30 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 79 | D4DIS6 | 522 | SUB10_TRIVH Subtilisin-like protease 10 OS=Tr... | 198 | 0.0001 | 48.5 | 27 | 41 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 80 | Q5VJ71 | 400 | SUB7_TRIVC Subtilisin-like protease 7 OS=Tric... | 189 | 0.0001 | 48.1 | 30 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 81 | D4CZQ4 | 420 | SUB7_TRIVH Subtilisin-like protease 7 OS=Tric... | 189 | 0.0001 | 48.1 | 30 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 82 | D4APA9 | 420 | SUB7_ARTBC Subtilisin-like protease 7 OS=(Tri... | 189 | 0.0001 | 48.1 | 30 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 83 | C5FH27 | 395 | SUB9_ARTOC Subtilisin-like protease 9 OS=cani... | 183 | 0.0002 | 47.8 | 28 | 45 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 84 | D4B5N1 | 402 | SUB9_ARTBC Subtilisin-like protease 9 OS=(Tri... | 190 | 0.0002 | 47.4 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 85 | P16588 | 534 | PROA_VIBAL Alkaline serine exoprotease A OS=V... | 191 | 0.0002 | 47.8 | 27 | 44 | | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 86 | P29121 | 655 | PCSK4_MOUSE Proprotein convertase subtilisin/... | 102 | 0.0002 | 47.8 | 35 | 52 | GO:0002080; C:acrosomal membrane; IDA:MGI.::GO:0005788; C:endoplasmic reticulum lumen; TAS:Reactome. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0007340; P:acrosome reaction; IMP:MGI.::GO:0007339; P:binding of sperm to zona pellucida; IMP:MGI.::GO:0006508; P:proteolysis; IBA:RefGenome.::GO:0048240; P:sperm capacitation; IMP:MGI. | 87 | D4D674 | 397 | SUB9_TRIVH Subtilisin-like protease 9 OS=Tric... | 190 | 0.0002 | 47.4 | 28 | 43 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 88 | Q9GLR1 | 753 | NEC1_BOVIN Neuroendocrine convertase 1 OS=Bos... | 123 | 0.0002 | 47.8 | 31 | 50 | GO:0005615; C:extracellular space; ISS:RefGenome.::GO:0005794; C:Golgi apparatus; ISS:RefGenome.::GO:0030133; C:transport vesicle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; ISS:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 89 | Q78EH2 | 678 | PCSK4_RAT Proprotein convertase subtilisin/ke... | 102 | 0.0003 | 47.4 | 34 | 53 | | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IBA:RefGenome. | | | | | | | | | | GO:0006508; P:proteolysis; IBA:RefGenome. | 90 | Q68GV9 | 382 | ALP_LECPS Alkaline serine protease ver112 OS=... | 188 | 0.0003 | 47 | 28 | 44 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0043086; P:negative regulation of catalytic activity; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW. | 91 | P09489 | 1045 | PRTS_SERMA Extracellular serine protease OS=S... | 110 | 0.0004 | 47.4 | 32 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0019867; C:outer membrane; IEA:InterPro. | | | | | | | | | | GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro. | | | | | | | | | | GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
