rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
241 | P66775 | 258 | BUTA_STAAM Diacetyl reductase [(S)-acetoin fo... | 214 | 0.000000000003 | 71.2 | 29 | 47 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 242 | Q5HJP2 | 258 | BUTA_STAAC Diacetyl reductase [(S)-acetoin fo... | 214 | 0.000000000003 | 71.2 | 29 | 47 | | | | | | | | | | | GO:0052588; F:diacetyl reductase ((S)-acetoin forming) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0045150; P:acetoin catabolic process; IEA:InterPro. | 243 | Q9BPX1 | 270 | DHB14_HUMAN 17-beta-hydroxysteroid dehydrogen... | 152 | 0.0000000002 | 65.9 | 28 | 47 | GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; IDA:HGNC. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:HGNC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0047045; F:testosterone 17-beta-dehydrogenase (NADP+) activity; IDA:HGNC. | | | | | | | | | | GO:0006706; P:steroid catabolic process; IDA:HGNC. | 244 | Q6PKH6 | 230 | DR4L2_HUMAN Dehydrogenase/reductase SDR famil... | 189 | 0.000000005 | 61.2 | 27 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 245 | Q8VCH7 | 341 | RDH10_MOUSE Retinol dehydrogenase 10 OS=Mus m... | 238 | 0.0000000001 | 67.4 | 24 | 41 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IMP:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IMP:MGI. | | | | | | | | | | GO:0060449; P:bud elongation involved in lung branching; IMP:MGI.::GO:0043583; P:ear development; IMP:MGI.::GO:0031076; P:embryonic camera-type eye development; IMP:MGI.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0048703; P:embryonic viscerocranium morphogenesis; IMP:MGI.::GO:0008406; P:gonad development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001656; P:metanephros development; IMP:MGI.::GO:0014032; P:neural crest cell development; IMP:MGI.::GO:0043584; P:nose development; IMP:MGI.::GO:0060431; P:primary lung bud formation; IMP:MGI.::GO:0002138; P:retinoic acid biosynthetic process; IMP:MGI. | 246 | Q80ZF7 | 341 | RDH10_RAT Retinol dehydrogenase 10 OS=Rattus ... | 238 | 0.00000000008 | 68.2 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 247 | P16543 | 249 | DHK2_STRVN Granaticin polyketide synthase put... | 182 | 0.00000000003 | 68.2 | 32 | 51 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW. | 248 | Q53217 | 548 | Y4VI_RHISN Uncharacterized short-chain type d... | 197 | 0.15 | 39.3 | 24 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 249 | Q8IZV5 | 341 | RDH10_HUMAN Retinol dehydrogenase 10 OS=Homo ... | 238 | 0.00000000006 | 68.6 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:UniProtKB.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB.::GO:0007601; P:visual perception; IDA:MGI. | 250 | Q8HZT6 | 341 | RDH10_BOVIN Retinol dehydrogenase 10 OS=Bos t... | 238 | 0.00000000006 | 68.6 | 24 | 42 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:MGI. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 251 | P50163 | 260 | TRN2_DATST Tropinone reductase 2 OS=Datura st... | 235 | 0.0000000002 | 65.9 | 29 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050358; F:tropinone reductase activity; IEA:EC. | | | | | | | | | | | 252 | Q5NVG2 | 300 | DHB11_PONAB Estradiol 17-beta-dehydrogenase 1... | 176 | 0.0000000002 | 66.2 | 28 | 47 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 253 | P87219 | 281 | SOU1_CANAL Sorbose reductase SOU1 OS=Candida ... | 227 | 0.000000000008 | 70.5 | 30 | 44 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IDA:CGD.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0032115; F:sorbose reductase activity; IDA:CGD. | | | | | | | | | | GO:0042850; P:L-sorbose catabolic process; IDA:CGD. | 254 | P05707 | 259 | SRLD_ECOLI Sorbitol-6-phosphate 2-dehydrogena... | 209 | 0.00000000001 | 69.7 | 26 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0009010; F:sorbitol-6-phosphate 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 255 | Q6P0H7 | 237 | CBR4_DANRE Carbonyl reductase family member 4... | 196 | 0.000000000009 | 69.7 | 32 | 48 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 256 | Q13268 | 258 | DHRS2_HUMAN Dehydrogenase/reductase SDR famil... | 186 | 0.00000006 | 58.2 | 28 | 45 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005635; C:nuclear envelope; IDA:UniProtKB. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008207; P:C21-steroid hormone metabolic process; NAS:UniProtKB.::GO:0034599; P:cellular response to oxidative stress; IDA:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; IEP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; NAS:UniProtKB.::GO:0009636; P:response to toxin; IDA:UniProtKB. | 257 | P15047 | 248 | ENTA_ECOLI 2,3-dihydro-2,3-dihydroxybenzoate ... | 190 | 0.000000000009 | 69.7 | 28 | 45 | | | | | | | | | | | GO:0008667; F:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity; IDA:EcoCyc.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009239; P:enterobactin biosynthetic process; IMP:EcoCyc. | 258 | Q29529 | 244 | CBR2_PIG Carbonyl reductase [NADPH] 2 OS=Sus ... | 194 | 0.000007 | 52 | 27 | 44 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 259 | P00335 | 249 | RIDH_ENTAE Ribitol 2-dehydrogenase OS=Enterob... | 185 | 0.0000000007 | 63.9 | 24 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050255; F:ribitol 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 260 | Q2TPA8 | 490 | HSDL2_MOUSE Hydroxysteroid dehydrogenase-like... | 197 | 0.000000000009 | 72 | 30 | 47 | GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 261 | P19871 | 254 | 3BHD_COMTE 3-beta-hydroxysteroid dehydrogenas... | 191 | 0.0001 | 48.5 | 25 | 40 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0030283; F:testosterone dehydrogenase [NAD(P) activity; IEA:EC. | | | | | | | | | | GO:0008202; P:steroid metabolic process; IEA:UniProtKB-KW.] | 262 | O05919 | 263 | Y927C_MYCTU Uncharacterized oxidoreductase Rv... | 201 | 0.0000000004 | 65.1 | 31 | 46 | GO:0005886; C:plasma membrane; IDA:MTBBASE. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 263 | Q6PAY8 | 417 | HSDL2_XENLA Hydroxysteroid dehydrogenase-like... | 175 | 0.00000000002 | 70.9 | 30 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 264 | Q8VCC1 | 269 | PGDH_MOUSE 15-hydroxyprostaglandin dehydrogen... | 198 | 0.0000000002 | 65.9 | 29 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; ISS:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; IMP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; ISS:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 265 | Q56318 | 256 | Y019_THEMA Uncharacterized oxidoreductase TM_... | 191 | 0.00000000006 | 67.4 | 29 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 266 | Q3T0C2 | 266 | PGDH_BOVIN 15-hydroxyprostaglandin dehydrogen... | 198 | 0.00000004 | 58.9 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; IDA:UniProtKB.::GO:0070403; F:NAD+ binding; ISS:UniProtKB.::GO:0004957; F:prostaglandin E receptor activity; ISS:UniProtKB. | | | | | | | | | | GO:0097070; P:ductus arteriosus closure; ISS:UniProtKB.::GO:0060206; P:estrous cycle phase; IEP:UniProtKB.::GO:0007565; P:female pregnancy; ISS:UniProtKB.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0030728; P:ovulation; ISS:UniProtKB.::GO:0007567; P:parturition; ISS:UniProtKB.::GO:0006693; P:prostaglandin metabolic process; IDA:UniProtKB.::GO:0070493; P:thrombin receptor signaling pathway; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB. | 267 | Q4V8F9 | 524 | HSDL2_RAT Hydroxysteroid dehydrogenase-like p... | 194 | 0.00000000009 | 68.9 | 28 | 45 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 268 | Q9EQ06 | 298 | DHB11_MOUSE Estradiol 17-beta-dehydrogenase 1... | 178 | 0.000000005 | 62.4 | 26 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. | 269 | Q66KC4 | 417 | HSDL2_XENTR Hydroxysteroid dehydrogenase-like... | 199 | 0.00000000005 | 69.7 | 31 | 46 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 270 | Q9BY49 | 303 | PECR_HUMAN Peroxisomal trans-2-enoyl-CoA redu... | 194 | 0.000000009 | 61.6 | 25 | 48 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0019166; F:trans-2-enoyl-CoA reductase (NADPH) activity; IDA:UniProtKB. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.::GO:0033306; P:phytol metabolic process; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro. | 271 | Q8NBQ5 | 300 | DHB11_HUMAN Estradiol 17-beta-dehydrogenase 1... | 176 | 0.0000000002 | 66.6 | 28 | 46 | GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006710; P:androgen catabolic process; IDA:HGNC.::GO:0006694; P:steroid biosynthetic process; IEA:UniProtKB-KW. |