rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
181 | Q9XT00 | 259 | DHB8_PIG Estradiol 17-beta-dehydrogenase 8 OS... | 200 | 0.0000000000003 | 74.3 | 33 | 50 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004303; F:estradiol 17-beta-dehydrogenase activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0050327; F:testosterone 17-beta-dehydrogenase (NAD+) activity; IEA:EC. | | | | | | | | | | GO:0006703; P:estrogen biosynthetic process; ISS:UniProtKB.::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 182 | Q9BTZ2 | 278 | DHRS4_HUMAN Dehydrogenase/reductase SDR famil... | 254 | 0.00000000000002 | 78.2 | 29 | 47 | GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000253; F:3-keto sterol reductase activity; IDA:UniProtKB.::GO:0018455; F:alcohol dehydrogenase [NAD(P)+ activity; IDA:UniProtKB.::GO:0004090; F:carbonyl reductase (NADPH) activity; IDA:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016655; F:oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; IDA:UniProtKB. | | | | | | | | | | GO:0006066; P:alcohol metabolic process; IDA:UniProtKB.::GO:0042180; P:cellular ketone metabolic process; IDA:UniProtKB.::GO:0051262; P:protein tetramerization; IDA:UniProtKB.::GO:0008202; P:steroid metabolic process; IDA:UniProtKB.] | 183 | O02691 | 261 | HCD2_BOVIN 3-hydroxyacyl-CoA dehydrogenase ty... | 233 | 0.0000000000007 | 73.2 | 29 | 44 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 184 | Q6DCT3 | 341 | RD10A_XENLA Retinol dehydrogenase 10-A OS=Xen... | 251 | 0.00000000003 | 69.7 | 24 | 43 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0052650; F:NADP-retinol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 185 | P47227 | 277 | BPHB_BURXL Cis-2,3-dihydrobiphenyl-2,3-diol d... | 184 | 0.0000000000005 | 73.9 | 33 | 47 | | | | | | | | | | | GO:0018509; F:cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0019439; P:aromatic compound catabolic process; IEA:UniProtKB-KW. | 186 | P40398 | 299 | YHXD_BACSU Uncharacterized oxidoreductase yhx... | 259 | 0.000000006 | 62 | 26 | 44 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 187 | Q68ER2 | 236 | CBR4_XENTR Carbonyl reductase family member 4... | 125 | 0.00000000000007 | 76.3 | 34 | 54 | GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW. | 188 | P39071 | 261 | DHBA_BACSU 2,3-dihydro-2,3-dihydroxybenzoate ... | 191 | 0.0000000000004 | 73.9 | 28 | 48 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008667; F:2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0009239; P:enterobactin biosynthetic process; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 189 | P50199 | 256 | GNO_GLUOX Gluconate 5-dehydrogenase OS=Glucon... | 203 | 0.00000000000008 | 76.3 | 30 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008874; F:gluconate 5-dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 190 | P06235 | 244 | NODG_RHIML Nodulation protein G OS=Rhizobium ... | 107 | 0.00000000000008 | 76.3 | 36 | 59 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0009877; P:nodulation; IEA:UniProtKB-KW. | 191 | P40397 | 285 | YHXC_BACSU Uncharacterized oxidoreductase yhx... | 229 | 0.00000000000003 | 78.2 | 28 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 192 | P0C0Y5 | 267 | MTDH_DAVTA Probable NADP-dependent mannitol d... | 210 | 0.0000000000007 | 73.6 | 30 | 45 | | | | | | | | | | | GO:0050085; F:mannitol 2-dehydrogenase (NADP+) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 193 | Q9BUT1 | 245 | BDH2_HUMAN 3-hydroxybutyrate dehydrogenase ty... | 196 | 0.0000000000001 | 75.9 | 30 | 47 | GO:0005737; C:cytoplasm; IDA:HGNC. | | | | | | | | | | GO:0003858; F:3-hydroxybutyrate dehydrogenase activity; IDA:HGNC.::GO:0051287; F:NAD binding; IDA:HGNC.::GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; ISS:UniProtKB. | | | | | | | | | | GO:0006635; P:fatty acid beta-oxidation; IDA:HGNC.::GO:0042168; P:heme metabolic process; ISS:UniProtKB.::GO:0055072; P:iron ion homeostasis; ISS:UniProtKB.::GO:0019290; P:siderophore biosynthetic process; ISS:UniProtKB. | 194 | Q9C826 | 285 | ABA2_ARATH Xanthoxin dehydrogenase OS=Arabido... | 215 | 0.00000000000006 | 77 | 27 | 50 | GO:0005829; C:cytosol; IDA:TAIR. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0010301; F:xanthoxin dehydrogenase activity; IDA:TAIR. | | | | | | | | | | GO:0009688; P:abscisic acid biosynthetic process; IMP:TAIR.::GO:0006561; P:proline biosynthetic process; IMP:TAIR.::GO:0010115; P:regulation of abscisic acid biosynthetic process; IMP:TAIR.::GO:0009750; P:response to fructose stimulus; IMP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.::GO:0009414; P:response to water deprivation; IMP:TAIR.::GO:0010182; P:sugar mediated signaling pathway; TAS:TAIR. | 195 | Q99LB2 | 279 | DHRS4_MOUSE Dehydrogenase/reductase SDR famil... | 259 | 0.0000000000005 | 73.9 | 28 | 44 | GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0004090; F:carbonyl reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 196 | O34717 | 254 | FADH_BACSU Probable 2,4-dienoyl-CoA reductase... | 229 | 0.0000000000002 | 75.1 | 29 | 46 | | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW. | 197 | Q8N3Y7 | 309 | RDHE2_HUMAN Epidermal retinol dehydrogenase 2... | 232 | 0.00000000000004 | 77.8 | 29 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004745; F:retinol dehydrogenase activity; IDA:UniProtKB. | | | | | | | | | | GO:0050908; P:detection of light stimulus involved in visual perception; NAS:UniProtKB.::GO:0043616; P:keratinocyte proliferation; IMP:UniProtKB.::GO:0042574; P:retinal metabolic process; IDA:UniProtKB.::GO:0042572; P:retinol metabolic process; IDA:UniProtKB. | 198 | O70351 | 261 | HCD2_RAT 3-hydroxyacyl-CoA dehydrogenase type... | 237 | 0.0000000000008 | 73.2 | 30 | 44 | | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; IEA:EC.::GO:0018454; F:acetoacetyl-CoA reductase activity; IDA:RGD.::GO:0001540; F:beta-amyloid binding; IDA:RGD.::GO:0004303; F:estradiol 17-beta-dehydrogenase activity; IDA:RGD.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0042802; F:identical protein binding; IDA:RGD.::GO:0051287; F:NAD binding; IDA:RGD.::GO:0005496; F:steroid binding; IDA:RGD. | | | | | | | | | | GO:0007569; P:cell aging; IEP:RGD.::GO:0033327; P:Leydig cell differentiation; IEP:RGD.::GO:0051289; P:protein homotetramerization; IDA:RGD.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 199 | Q56840 | 250 | HCDR_XANP2 2-(R)-hydroxypropyl-CoM dehydrogen... | 183 | 0.000000000002 | 72 | 30 | 49 | | | | | | | | | | | GO:0050574; F:2-(R)-hydroxypropyl-CoM dehydrogenase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 200 | P31808 | 252 | YCIK_ECOLI Uncharacterized oxidoreductase yci... | 246 | 0.000000009 | 60.8 | 23 | 46 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 201 | Q5RA68 | 418 | HSDL2_PONAB Hydroxysteroid dehydrogenase-like... | 146 | 0.000000000003 | 73.2 | 36 | 50 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 202 | Q9MYP6 | 270 | DHB14_BOVIN 17-beta-hydroxysteroid dehydrogen... | 179 | 0.0000000000002 | 74.7 | 33 | 51 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 203 | P37079 | 267 | SORD_KLEPN Sorbitol-6-phosphate 2-dehydrogena... | 206 | 0.000000000005 | 70.9 | 28 | 47 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0009010; F:sorbitol-6-phosphate 2-dehydrogenase activity; IEA:EC. | | | | | | | | | | | 204 | Q2KIJ5 | 331 | KDSR_BOVIN 3-ketodihydrosphingosine reductase... | 196 | 0.000000000002 | 72.8 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 205 | Q5RBV3 | 292 | DECR2_PONAB Peroxisomal 2,4-dienoyl-CoA reduc... | 199 | 0.000005 | 52.8 | 26 | 40 | GO:0005777; C:peroxisome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008670; F:2,4-dienoyl-CoA reductase (NADPH) activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | | 206 | Q99714 | 261 | HCD2_HUMAN 3-hydroxyacyl-CoA dehydrogenase ty... | 208 | 0.0000000000003 | 74.3 | 31 | 47 | GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:ProtInc. | | | | | | | | | | GO:0047015; F:3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity; IEA:EC.::GO:0003857; F:3-hydroxyacyl-CoA dehydrogenase activity; EXP:Reactome.::GO:0008709; F:cholate 7-alpha-dehydrogenase activity; TAS:ProtInc. | | | | | | | | | | GO:0009083; P:branched chain family amino acid catabolic process; TAS:Reactome.::GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0008033; P:tRNA processing; IEA:UniProtKB-KW. | 207 | Q06136 | 332 | KDSR_HUMAN 3-ketodihydrosphingosine reductase... | 196 | 0.000000000001 | 73.6 | 28 | 48 | GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0005615; C:extracellular space; TAS:ProtInc.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0047560; F:3-dehydrosphinganine reductase activity; IDA:MGI.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0006666; P:3-keto-sphinganine metabolic process; IDA:MGI.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome. | 208 | Q6YN16 | 418 | HSDL2_HUMAN Hydroxysteroid dehydrogenase-like... | 146 | 0.000000000005 | 72.8 | 36 | 49 | GO:0005777; C:peroxisome; IDA:UniProtKB. | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0032934; F:sterol binding; IEA:InterPro. | | | | | | | | | | | 209 | P50200 | 267 | HDHA_CLOSO NADP-dependent 7-alpha-hydroxyster... | 262 | 0.0000000006 | 64.7 | 24 | 43 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030573; P:bile acid catabolic process; IEA:UniProtKB-KW. | 210 | P50160 | 336 | TS2_MAIZE Sex determination protein tasselsee... | 199 | 0.000000000002 | 73.2 | 30 | 48 | | | | | | | | | | | GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 211 | Q8NK50 | 266 | DCXR_HYPJE L-xylulose reductase OS=Hypocrea j... | 189 | 0.0000000006 | 64.3 | 31 | 45 | | | | | | | | | | | GO:0050038; F:L-xylulose reductase (NADP+) activity; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro. | | | | | | | | | | GO:0042732; P:D-xylose metabolic process; IEA:UniProtKB-KW.::GO:0006006; P:glucose metabolic process; ISS:UniProtKB.::GO:0051289; P:protein homotetramerization; ISS:UniProtKB.::GO:0005997; P:xylulose metabolic process; ISS:UniProtKB. |