rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
541 | P58546 | 118 | MTPN_HUMAN Myotrophin OS=Homo sapiens (Human)... | 57 | 0.38 | 36.2 | 39 | 53 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0008290; C:F-actin capping protein complex; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0016049; P:cell growth; IDA:UniProtKB.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; IDA:UniProtKB.::GO:0016202; P:regulation of striated muscle tissue development; NAS:UniProtKB.::GO:0006417; P:regulation of translation; NAS:UniProtKB. | 542 | Q863Z4 | 118 | MTPN_CANFA Myotrophin OS=Canis familiaris (Do... | 57 | 0.38 | 36.2 | 39 | 53 | GO:0030424; C:axon; ISS:AgBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB. | 543 | Q3T0F7 | 118 | MTPN_BOVIN Myotrophin OS=Bos taurus (Bovine).... | 57 | 0.38 | 36.2 | 39 | 53 | GO:0030424; C:axon; ISS:AgBase.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB. | 544 | Q6AFL2 | 254 | Y958_LEIXX Putative ankyrin-containing lipopr... | 161 | 0.009 | 43.1 | 28 | 45 | GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 545 | P62775 | 118 | MTPN_RAT Myotrophin OS=Rattus norvegicus (Rat... | 57 | 0.4 | 36.2 | 39 | 53 | GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0006584; P:catecholamine metabolic process; IEP:RGD.::GO:0021707; P:cerebellar granule cell differentiation; IEP:RGD.::GO:0010613; P:positive regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0030307; P:positive regulation of cell growth; IDA:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; IDA:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; IDA:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB.::GO:0043403; P:skeletal muscle tissue regeneration; IEP:RGD.::GO:0051146; P:striated muscle cell differentiation; IEP:RGD. | 546 | P62774 | 118 | MTPN_MOUSE Myotrophin OS=Mus musculus (Mouse)... | 57 | 0.4 | 36.2 | 39 | 53 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0010613; P:positive regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; ISS:UniProtKB.::GO:0010557; P:positive regulation of macromolecule biosynthetic process; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0051247; P:positive regulation of protein metabolic process; ISS:UniProtKB.::GO:2000812; P:regulation of barbed-end actin filament capping; ISS:UniProtKB. | 547 | Q5JPF3 | 1778 | AN36C_HUMAN Ankyrin repeat domain-containing ... | 265 | 0.0003 | 49.3 | 25 | 40 | | | | | | | | | | | GO:0008200; F:ion channel inhibitor activity; NAS:UniProtKB. | | | | | | | | | | | 548 | P83757 | 489 | CACT_DROYA NF-kappa-B inhibitor cactus OS=Dro... | 144 | 0.023 | 42.4 | 28 | 45 | GO:0005737; C:cytoplasm; ISS:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0046843; P:dorsal appendage formation; ISS:UniProtKB.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 549 | Q6TNT2 | 228 | ANR46_DANRE Ankyrin repeat domain-containing ... | 117 | 0.037 | 40.8 | 32 | 47 | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. | | | | | | | | | | | | | | | | | | | | | 550 | Q8WVL7 | 239 | ANR49_HUMAN Ankyrin repeat domain-containing ... | 93 | 0.005 | 43.5 | 28 | 49 | GO:0005634; C:nucleus; IC:UniProtKB. | | | | | | | | | | | | | | | | | | | | GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB. | 551 | Q6DRG7 | 1049 | MYPT1_DANRE Protein phosphatase 1 regulatory ... | 217 | 0.0006 | 47.8 | 26 | 40 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0072357; C:PTW/PP1 phosphatase complex; ISS:UniProtKB. | | | | | | | | | | GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0019208; F:phosphatase regulator activity; ISS:UniProtKB. | | | | | | | | | | GO:0051017; P:actin filament bundle assembly; IMP:ZFIN.::GO:0001889; P:liver development; IMP:ZFIN.::GO:0030155; P:regulation of cell adhesion; ISS:UniProtKB.::GO:0035507; P:regulation of myosin-light-chain-phosphatase activity; ISS:UniProtKB. | 552 | Q9BE45 | 719 | IKBZ_BOVIN NF-kappa-B inhibitor zeta OS=Bos t... | 221 | 0.41 | 38.5 | 26 | 42 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 553 | Q6UB98 | 2062 | ANR12_HUMAN Ankyrin repeat domain-containing ... | 97 | 1.5 | 37 | 31 | 45 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA. | | | | | | | | | | | | | | | | | | | | | 554 | Q24145 | 939 | SHARK_DROME Tyrosine-protein kinase shark OS=... | 142 | 0.11 | 40.4 | 24 | 43 | GO:0005938; C:cell cortex; IDA:FlyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; NAS:FlyBase. | | | | | | | | | | GO:0043277; P:apoptotic cell clearance; IMP:FlyBase.::GO:0046843; P:dorsal appendage formation; IMP:FlyBase.::GO:0007394; P:dorsal closure, elongation of leading edge cells; IMP:FlyBase.::GO:0007254; P:JNK cascade; IMP:FlyBase.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IEP:UniProtKB. | 555 | Q02979 | 1223 | GDE1_YEAST Glycerophosphodiester phosphodiest... | 220 | 0.001 | 46.6 | 24 | 38 | GO:0005737; C:cytoplasm; IDA:SGD. | | | | | | | | | | GO:0047389; F:glycerophosphocholine phosphodiesterase activity; IMP:SGD.::GO:0008889; F:glycerophosphodiester phosphodiesterase activity; IEA:EC.::GO:0004629; F:phospholipase C activity; IEA:InterPro. | | | | | | | | | | GO:0006071; P:glycerol metabolic process; IEA:InterPro.::GO:0046475; P:glycerophospholipid catabolic process; IMP:SGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 556 | Q7T2B9 | 118 | MTPN_DANRE Myotrophin OS=Danio rerio (Zebrafi... | 70 | 0.004 | 42.4 | 40 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 557 | Q5UPG6 | 413 | YL092_MIMIV Putative ankyrin repeat protein L... | 152 | 0.002 | 45.8 | 22 | 43 | | | | | | | | | | | | | | | | | | | | | | 558 | Q6TNJ1 | 736 | KRIT1_BOVIN Krev interaction trapped protein ... | 73 | 0.1 | 40.4 | 29 | 53 | GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0016525; P:negative regulation of angiogenesis; ISS:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; ISS:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; ISS:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; ISS:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; ISS:UniProtKB. | 559 | O60237 | 982 | MYPT2_HUMAN Protein phosphatase 1 regulatory ... | 197 | 0.74 | 37.7 | 26 | 37 | GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA. | | | | | | | | | | GO:0008047; F:enzyme activator activity; TAS:ProtInc. | | | | | | | | | | GO:0006937; P:regulation of muscle contraction; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc. | 560 | O00522 | 736 | KRIT1_HUMAN Krev interaction trapped protein ... | 75 | 6.7 | 34.7 | 32 | 44 | GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005083; F:small GTPase regulator activity; TAS:ProtInc. | | | | | | | | | | GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IMP:UniProtKB.::GO:0016525; P:negative regulation of angiogenesis; IMP:UniProtKB.::GO:2000352; P:negative regulation of endothelial cell apoptotic process; IMP:UniProtKB.::GO:0010596; P:negative regulation of endothelial cell migration; IMP:UniProtKB.::GO:0001937; P:negative regulation of endothelial cell proliferation; IMP:UniProtKB.::GO:2000114; P:regulation of establishment of cell polarity; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:ProtInc. | 561 | Q4R739 | 496 | ANR53_MACFA Ankyrin repeat domain-containing ... | 82 | 0.01 | 43.5 | 30 | 46 | | | | | | | | | | | | | | | | | | | | | | 562 | Q8BG95 | 976 | MYPT2_MOUSE Protein phosphatase 1 regulatory ... | 192 | 2 | 36.2 | 27 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 563 | Q54LF0 | 778 | SIR2B_DICDI NAD-dependent deacetylase sir2B O... | 333 | 0.00002 | 52.4 | 21 | 37 | | | | | | | | | | | GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0070403; F:NAD+ binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006476; P:protein deacetylation; IEA:InterPro. | 564 | Q60773 | 166 | CDN2D_MOUSE Cyclin-dependent kinase 4 inhibit... | 75 | 1.1 | 35.8 | 33 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW. | 565 | Q9Z205 | 269 | RFXK_MOUSE DNA-binding protein RFXANK OS=Mus ... | 126 | 0.000006 | 52.8 | 31 | 43 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IDA:MGI. | | | | | | | | | | GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007265; P:Ras protein signal transduction; IPI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 566 | P25799 | 971 | NFKB1_MOUSE Nuclear factor NF-kappa-B p105 su... | 87 | 3.6 | 35.4 | 33 | 46 | GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IDA:MGI.::GO:0000975; F:regulatory region DNA binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0048535; P:lymph node development; TAS:MGI.::GO:0001818; P:negative regulation of cytokine production; IMP:BHF-UCL.::GO:0045083; P:negative regulation of interleukin-12 biosynthetic process; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 567 | Q9J505 | 188 | V230_FOWPN Putative ankyrin repeat protein FP... | 183 | 0.16 | 38.5 | 22 | 39 | | | | | | | | | | | | | | | | | | | | | | 568 | Q8N9V6 | 530 | ANR53_HUMAN Ankyrin repeat domain-containing ... | 110 | 0.48 | 38.1 | 30 | 45 | | | | | | | | | | | | | | | | | | | | | | 569 | Q10311 | 234 | YD58_SCHPO Ankyrin repeat-containing protein ... | 164 | 0.000001 | 54.7 | 28 | 41 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005838; C:proteasome regulatory particle; ISS:PomBase. | | | | | | | | | | | | | | | | | | | | GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; NAS:PomBase. | 570 | Q86AT8 | 638 | SPKA_DICDI Stress-activated protein kinase al... | 99 | 0.001 | 47 | 31 | 49 | GO:0015629; C:actin cytoskeleton; IDA:dictyBase.::GO:0005737; C:cytoplasm; IDA:dictyBase. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0050793; P:regulation of developmental process; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IDA:dictyBase. | 571 | A9JR78 | 1427 | TONSL_DANRE Tonsoku-like protein OS=Danio rer... | 122 | 0.00006 | 51.2 | 30 | 42 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043596; C:nuclear replication fork; ISS:UniProtKB. | | | | | | | | | | GO:0042393; F:histone binding; ISS:UniProtKB. | | | | | | | | | | GO:0000724; P:double-strand break repair via homologous recombination; ISS:UniProtKB.::GO:0031297; P:replication fork processing; ISS:UniProtKB. |